Helen I Zgurskaya

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 66

Top Topics

Pseudomonas Aeruginosa

Molecular Dynamics

Top Venues

ACS infectious diseases

Antimicrobial agents and chemotherapy

Journal of bacteriology

Journal of medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Pedro D Manrique, Inga V Leus, César A López, Jitender Mehla, Giuliano Malloci, Silvia Gervasoni, Attilio V Vargiu, Rama K Kinthada, Liam Herndon, Nicolas W Hengartner, John K Walker, Valentin V Rybenkov, Paolo Ruggerone, Helen I Zgurskaya, Sandrasegaram Gnanakaran
Predicting permeation of compounds across the outer membrane of P. aeruginosa using molecular descriptors. Communications chemistry 7 (1) (2024)
Pedro D Manrique, Inga V Leus, César A López, Jitender Mehla, Giuliano Malloci, Silvia Gervasoni, Attilio V Vargiu, Rama K Kinthada, Liam Herndon, Nicolas W Hengartner, John K Walker, Valentin V Rybenkov, Paolo Ruggerone, Helen I Zgurskaya, Sandrasegaram Gnanakaran
Predicting permeation of compounds across the outer membrane of P. aeruginosa using molecular descriptors. Communications chemistry 7 (1) (2024)
Justyna W Adamiak, Laiba Ajmal, Helen I Zgurskaya
Non-interchangeable functions of efflux transporters of Pseudomonas aeruginosa in survival under infection-associated stress. Journal of bacteriology (2024)
Rushikesh Tambat, Rama Kumar Kinthada, Aysegul Saral Sariyer, Inga V Leus, Emrah Sariyer, Napoleon D'Cunha, Hinman Zhou, Makaila Leask, John K Walker, Helen I Zgurskaya
AdeIJK Pump-Specific Inhibitors Effective against Multidrug Resistant Acinetobacter baumannii . ACS infectious diseases (2024)
Justyna W Adamiak, Laiba Ajmal, Helen I Zgurskaya
Non-interchangeable functions of efflux transporters of Pseudomonas aeruginosa in survival under infection-associated stress. Journal of bacteriology 206 (7) (2024)
Justyna W Adamiak, Laiba Ajmal, Helen I Zgurskaya
Non-interchangeable functions of efflux transporters of Pseudomonas aeruginosa in survival under infection-associated stress. Journal of bacteriology 206 (7) (2024)
Svitlana Babii, Wei Li, Lixinhao Yang, Anna E Grzegorzewicz, Mary Jackson, James C Gumbart, Helen I Zgurskaya
Allosteric coupling of substrate binding and proton translocation in MmpL3 transporter from Mycobacterium tuberculosis . mBio (2024)
Justyna W Adamiak, Laiba Ajmal, Helen I Zgurskaya
Non-interchangeable functions of efflux transporters of Pseudomonas aeruginosa in survival under infection-associated stress. Journal of bacteriology (2024)
Justyna W Adamiak, Laiba Ajmal, Helen I Zgurskaya
Non-interchangeable functions of efflux transporters of Pseudomonas aeruginosa in survival under infection-associated stress. Journal of bacteriology 206 (7) (2024)
Rushikesh Tambat, Rama Kumar Kinthada, Aysegul Saral Sariyer, Inga V Leus, Emrah Sariyer, Napoleon D'Cunha, Hinman Zhou, Makaila Leask, John K Walker, Helen I Zgurskaya
AdeIJK Pump-Specific Inhibitors Effective against Multidrug Resistant Acinetobacter baumannii . ACS infectious diseases 10 (6) (2024)
Benjamin Russell Lewis, Muhammad R Uddin, Katie M Kuo, Laila M N Shah, Nicola J Harris, Paula J Booth, Dietmar Hammerschmid, James C Gumbart, Helen I Zgurskaya, Eamonn Reading
Mg 2+ -dependent mechanism of environmental versatility in a multidrug efflux pump. bioRxiv : the preprint server for biology (2024)
Justyna W Adamiak, Laiba Ajmal, Helen I Zgurskaya
Non-interchangeable functions of efflux transporters of Pseudomonas aeruginosa in survival under infection-associated stress. Journal of bacteriology 206 (7) (2024)
Pedro D Manrique, Inga V Leus, César A López, Jitender Mehla, Giuliano Malloci, Silvia Gervasoni, Attilio V Vargiu, Rama K Kinthada, Liam Herndon, Nicolas W Hengartner, John K Walker, Valentin V Rybenkov, Paolo Ruggerone, Helen I Zgurskaya, Sandrasegaram Gnanakaran
Predicting permeation of compounds across the outer membrane of P. aeruginosa using molecular descriptors. Communications chemistry 7 (1) (2024)
Benjamin Russell Lewis, Muhammad R Uddin, Katie M Kuo, Laila M N Shah, Nicola J Harris, Paula J Booth, Dietmar Hammerschmid, James C Gumbart, Helen I Zgurskaya, Eamonn Reading
Mg 2+ -dependent mechanism of environmental versatility in a multidrug efflux pump. bioRxiv : the preprint server for biology (2024)
Justyna W Adamiak, Laiba Ajmal, Helen I Zgurskaya
Non-interchangeable functions of efflux transporters of Pseudomonas aeruginosa in survival under infection-associated stress. Journal of bacteriology 206 (7) (2024)
Inga V Leus, Justyna Adamiak, Brinda Chandar, Vincent Bonifay, Shibin Zhao, Scott S Walker, Brian Squadroni, Carl J Balibar, Nihar Kinarivala, Lisa C Standke, Henning U Voss, Derek S Tan, Valentin V Rybenkov, Helen I Zgurskaya
Functional Diversity of Gram-Negative Permeability Barriers Reflected in Antibacterial Activities and Intracellular Accumulation of Antibiotics. Antimicrobial agents and chemotherapy 67 (2) (2023)
Inga V Leus, Justyna Adamiak, Brinda Chandar, Vincent Bonifay, Shibin Zhao, Scott S Walker, Brian Squadroni, Carl J Balibar, Nihar Kinarivala, Lisa C Standke, Henning U Voss, Derek S Tan, Valentin V Rybenkov, Helen I Zgurskaya
Functional Diversity of Gram-Negative Permeability Barriers Reflected in Antibacterial Activities and Intracellular Accumulation of Antibiotics. Antimicrobial agents and chemotherapy 67 (2) (2023)
Benjamin Russell Lewis, Muhammad R Uddin, Mohammad Moniruzzaman, Katie M Kuo, Anna J Higgins, Laila M N Shah, Frank Sobott, Jerry M Parks, Dietmar Hammerschmid, James C Gumbart, Helen I Zgurskaya, Eamonn Reading
Conformational restriction shapes the inhibition of a multidrug efflux adaptor protein. Nature communications 14 (1) (2023)
Inga V Leus, Justyna Adamiak, Brinda Chandar, Vincent Bonifay, Shibin Zhao, Scott S Walker, Brian Squadroni, Carl J Balibar, Nihar Kinarivala, Lisa C Standke, Henning U Voss, Derek S Tan, Valentin V Rybenkov, Helen I Zgurskaya
Functional Diversity of Gram-Negative Permeability Barriers Reflected in Antibacterial Activities and Intracellular Accumulation of Antibiotics. Antimicrobial agents and chemotherapy 67 (2) (2023)
Marianna Stampolaki, Ioannis P Papanastasiou, Helen I Zgurskaya, Antonios D Kolocouris
Study of SQ109 analogs binding to mycobacterium MmpL3 transporter using MD simulations and alchemical relative binding free energy calculations. Journal of computer-aided molecular design (2023)
Inga V Leus, Justyna Adamiak, Brinda Chandar, Vincent Bonifay, Shibin Zhao, Scott S Walker, Brian Squadroni, Carl J Balibar, Nihar Kinarivala, Lisa C Standke, Henning U Voss, Derek S Tan, Valentin V Rybenkov, Helen I Zgurskaya
Functional Diversity of Gram-Negative Permeability Barriers Reflected in Antibacterial Activities and Intracellular Accumulation of Antibiotics. Antimicrobial agents and chemotherapy (2023)
Marianna Stampolaki, Satish R Malwal, Nadine Alvarez-Cabrera, Zijun Gao, Mohammad Moniruzzaman, Svitlana O Babii, Nikolaos Naziris, André Rey-Cibati, Mariana Valladares-Delgado, Andreea L Turcu, Kyung-Hwa Baek, Trong-Nhat Phan, Hyeryon Lee, Mattheo Alcaraz, Savannah Watson, Mariette van der Watt, Dina Coertzen, Natasa Efstathiou, Maria Chountoulesi, Carolyn M Shoen, Ioannis P Papanastasiou, Jose Brea, Michael H Cynamon, Lyn-Marié Birkholtz, Laurent Kremer, Joo Hwan No, Santiago Vázquez, Gustavo Benaim, Costas Demetzos, Helen I Zgurskaya, Thomas Dick, Eric Oldfield, Antonios D Kolocouris
Synthesis and Testing of Analogs of the Tuberculosis Drug Candidate SQ109 against Bacteria and Protozoa: Identification of Lead Compounds against Mycobacterium abscessus and Malaria Parasites. ACS infectious diseases 9 (2) (2023)
Inga V Leus, Justyna Adamiak, Brinda Chandar, Vincent Bonifay, Shibin Zhao, Scott S Walker, Brian Squadroni, Carl J Balibar, Nihar Kinarivala, Lisa C Standke, Henning U Voss, Derek S Tan, Valentin V Rybenkov, Helen I Zgurskaya
Functional Diversity of Gram-Negative Permeability Barriers Reflected in Antibacterial Activities and Intracellular Accumulation of Antibiotics. Antimicrobial agents and chemotherapy (2023)
Marianna Stampolaki, Satish R Malwal, Nadine Alvarez-Cabrera, Zijun Gao, Mohammad Moniruzzaman, Svitlana O Babii, Nikolaos Naziris, André Rey-Cibati, Mariana Valladares-Delgado, Andreea L Turcu, Kyung-Hwa Baek, Trong-Nhat Phan, Hyeryon Lee, Mattheo Alcaraz, Savannah Watson, Mariette van der Watt, Dina Coertzen, Natasa Efstathiou, Maria Chountoulesi, Carolyn M Shoen, Ioannis P Papanastasiou, Jose Brea, Michael H Cynamon, Lyn-Marié Birkholtz, Laurent Kremer, Joo Hwan No, Santiago Vázquez, Gustavo Benaim, Costas Demetzos, Helen I Zgurskaya, Thomas Dick, Eric Oldfield, Antonios D Kolocouris
Synthesis and Testing of Analogs of the Tuberculosis Drug Candidate SQ109 against Bacteria and Protozoa: Identification of Lead Compounds against Mycobacterium abscessus and Malaria Parasites. ACS infectious diseases 9 (2) (2023)
Marianna Stampolaki, Satish R Malwal, Nadine Alvarez-Cabrera, Zijun Gao, Mohammad Moniruzzaman, Svitlana O Babii, Nikolaos Naziris, André Rey-Cibati, Mariana Valladares-Delgado, Andreea L Turcu, Kyung-Hwa Baek, Trong-Nhat Phan, Hyeryon Lee, Mattheo Alcaraz, Savannah Watson, Mariette van der Watt, Dina Coertzen, Natasa Efstathiou, Maria Chountoulesi, Carolyn M Shoen, Ioannis P Papanastasiou, Jose Brea, Michael H Cynamon, Lyn-Marié Birkholtz, Laurent Kremer, Joo Hwan No, Santiago Vázquez, Gustavo Benaim, Costas Demetzos, Helen I Zgurskaya, Thomas Dick, Eric Oldfield, Antonios D Kolocouris
Synthesis and Testing of Analogs of the Tuberculosis Drug Candidate SQ109 against Bacteria and Protozoa: Identification of Lead Compounds against Mycobacterium abscessus and Malaria Parasites. ACS infectious diseases 9 (2) (2023)
Inga V Leus, Justyna Adamiak, Brinda Chandar, Vincent Bonifay, Shibin Zhao, Scott S Walker, Brian Squadroni, Carl J Balibar, Nihar Kinarivala, Lisa C Standke, Henning U Voss, Derek S Tan, Valentin V Rybenkov, Helen I Zgurskaya
Functional Diversity of Gram-Negative Permeability Barriers Reflected in Antibacterial Activities and Intracellular Accumulation of Antibiotics. Antimicrobial agents and chemotherapy 67 (2) (2023)
Inga V Leus, Sean R Roberts, Anhthu Trinh, Edward W Yu, Helen I Zgurskaya
Nonadditive functional interactions between ligand-binding sites of the multidrug efflux pump AdeB from Acinetobacter baumannii . Journal of bacteriology (2023)
Marianna Stampolaki, Satish R Malwal, Nadine Alvarez-Cabrera, Zijun Gao, Mohammad Moniruzzaman, Svitlana O Babii, Nikolaos Naziris, André Rey-Cibati, Mariana Valladares-Delgado, Andreea L Turcu, Kyung-Hwa Baek, Trong-Nhat Phan, Hyeryon Lee, Mattheo Alcaraz, Savannah Watson, Mariette van der Watt, Dina Coertzen, Natasa Efstathiou, Maria Chountoulesi, Carolyn M Shoen, Ioannis P Papanastasiou, Jose Brea, Michael H Cynamon, Lyn-Marié Birkholtz, Laurent Kremer, Joo Hwan No, Santiago Vázquez, Gustavo Benaim, Costas Demetzos, Helen I Zgurskaya, Thomas Dick, Eric Oldfield, Antonios D Kolocouris
Synthesis and Testing of Analogs of the Tuberculosis Drug Candidate SQ109 against Bacteria and Protozoa: Identification of Lead Compounds against Mycobacterium abscessus and Malaria Parasites. ACS infectious diseases (2023)
Inga V Leus, Justyna Adamiak, Brinda Chandar, Vincent Bonifay, Shibin Zhao, Scott S Walker, Brian Squadroni, Carl J Balibar, Nihar Kinarivala, Lisa C Standke, Henning U Voss, Derek S Tan, Valentin V Rybenkov, Helen I Zgurskaya
Functional Diversity of Gram-Negative Permeability Barriers Reflected in Antibacterial Activities and Intracellular Accumulation of Antibiotics. Antimicrobial agents and chemotherapy 67 (2) (2023)
Inga V Leus, Justyna Adamiak, Brinda Chandar, Vincent Bonifay, Shibin Zhao, Scott S Walker, Brian Squadroni, Carl J Balibar, Nihar Kinarivala, Lisa C Standke, Henning U Voss, Derek S Tan, Valentin V Rybenkov, Helen I Zgurskaya
Functional Diversity of Gram-Negative Permeability Barriers Reflected in Antibacterial Activities and Intracellular Accumulation of Antibiotics. Antimicrobial agents and chemotherapy (2023)
Marianna Stampolaki, Satish R Malwal, Nadine Alvarez-Cabrera, Zijun Gao, Mohammad Moniruzzaman, Svitlana O Babii, Nikolaos Naziris, André Rey-Cibati, Mariana Valladares-Delgado, Andreea L Turcu, Kyung-Hwa Baek, Trong-Nhat Phan, Hyeryon Lee, Mattheo Alcaraz, Savannah Watson, Mariette van der Watt, Dina Coertzen, Natasa Efstathiou, Maria Chountoulesi, Carolyn M Shoen, Ioannis P Papanastasiou, Jose Brea, Michael H Cynamon, Lyn-Marié Birkholtz, Laurent Kremer, Joo Hwan No, Santiago Vázquez, Gustavo Benaim, Costas Demetzos, Helen I Zgurskaya, Thomas Dick, Eric Oldfield, Antonios D Kolocouris
Synthesis and Testing of Analogs of the Tuberculosis Drug Candidate SQ109 against Bacteria and Protozoa: Identification of Lead Compounds against Mycobacterium abscessus and Malaria Parasites. ACS infectious diseases 9 (2) (2023)
Ziwei Hu, Inga V Leus, Brinda Chandar, Bradley S Sherborne, Quentin P Avila, Valentin V Rybenkov, Helen I Zgurskaya, Adam S Duerfeldt
Correction to "Structure-Uptake Relationship Studies of Oxazolidinones in Gram-Negative ESKAPE Pathogens". Journal of medicinal chemistry (2023)
Marianna Stampolaki, Satish R Malwal, Nadine Alvarez-Cabrera, Zijun Gao, Mohammad Moniruzzaman, Svitlana O Babii, Nikolaos Naziris, André Rey-Cibati, Mariana Valladares-Delgado, Andreea L Turcu, Kyung-Hwa Baek, Trong-Nhat Phan, Hyeryon Lee, Mattheo Alcaraz, Savannah Watson, Mariette van der Watt, Dina Coertzen, Natasa Efstathiou, Maria Chountoulesi, Carolyn M Shoen, Ioannis P Papanastasiou, Jose Brea, Michael H Cynamon, Lyn-Marié Birkholtz, Laurent Kremer, Joo Hwan No, Santiago Vázquez, Gustavo Benaim, Costas Demetzos, Helen I Zgurskaya, Thomas Dick, Eric Oldfield, Antonios D Kolocouris
Synthesis and Testing of Analogs of the Tuberculosis Drug Candidate SQ109 against Bacteria and Protozoa: Identification of Lead Compounds against Mycobacterium abscessus and Malaria Parasites. ACS infectious diseases (2023)
Marianna Stampolaki, Satish R Malwal, Nadine Alvarez-Cabrera, Zijun Gao, Mohammad Moniruzzaman, Svitlana O Babii, Nikolaos Naziris, André Rey-Cibati, Mariana Valladares-Delgado, Andreea L Turcu, Kyung-Hwa Baek, Trong-Nhat Phan, Hyeryon Lee, Mattheo Alcaraz, Savannah Watson, Mariette van der Watt, Dina Coertzen, Natasa Efstathiou, Maria Chountoulesi, Carolyn M Shoen, Ioannis P Papanastasiou, Jose Brea, Michael H Cynamon, Lyn-Marié Birkholtz, Laurent Kremer, Joo Hwan No, Santiago Vázquez, Gustavo Benaim, Costas Demetzos, Helen I Zgurskaya, Thomas Dick, Eric Oldfield, Antonios D Kolocouris
Synthesis and Testing of Analogs of the Tuberculosis Drug Candidate SQ109 against Bacteria and Protozoa: Identification of Lead Compounds against Mycobacterium abscessus and Malaria Parasites. ACS infectious diseases (2023)
Silvia Gervasoni, Jitender Mehla, Charles R Bergen, Inga V Leus, Enrico Margiotta, Giuliano Malloci, Andrea Bosin, Attilio V Vargiu, Olga Lomovskaya, Valentin V Rybenkov, Paolo Ruggerone, Helen I Zgurskaya
Molecular determinants of avoidance and inhibition of Pseudomonas aeruginosa MexB efflux pump. mBio (2023)
Inga V Leus, Justyna Adamiak, Brinda Chandar, Vincent Bonifay, Shibin Zhao, Scott S Walker, Brian Squadroni, Carl J Balibar, Nihar Kinarivala, Lisa C Standke, Henning U Voss, Derek S Tan, Valentin V Rybenkov, Helen I Zgurskaya
Functional Diversity of Gram-Negative Permeability Barriers Reflected in Antibacterial Activities and Intracellular Accumulation of Antibiotics. Antimicrobial agents and chemotherapy 67 (2) (2023)
Pankaj Bhattarai, Pooja Hegde, Wei Li, Pavan Kumar Prathipati, Casey M Stevens, Lixinhao Yang, Hinman Zhou, Amit Pandya, Katie Cunningham, Jenny Grissom, Mariaelena Roman Sotelo, Melanie Sowards, Lilian Calisto, Christopher J Destache, Sonia Rocha-Sanchez, James C Gumbart, Helen I Zgurskaya, Mary Jackson, E Jeffrey North
Structural Determinants of Indole-2-carboxamides: Identification of Lead Acetamides with Pan Antimycobacterial Activity. Journal of medicinal chemistry (2022)
Silvia Gervasoni, Giuliano Malloci, Andrea Bosin, Attilio Vittorio Vargiu, Helen I Zgurskaya, Paolo Ruggerone
Recognition of quinolone antibiotics by the multidrug efflux transporter MexB of Pseudomonas aeruginosa . Physical chemistry chemical physics : PCCP 24 (27) (2022)
Mohammad Moniruzzaman, Connor J Cooper, Muhammad R Uddin, John K Walker, Jerry M Parks, Helen I Zgurskaya
Analysis of Orthogonal Efflux and Permeation Properties of Compounds Leads to the Discovery of New Efflux Pump Inhibitors. ACS infectious diseases 8 (10) (2022)
Pankaj Bhattarai, Pooja Hegde, Wei Li, Pavan Kumar Prathipati, Casey M Stevens, Lixinhao Yang, Hinman Zhou, Amit Pandya, Katie Cunningham, Jenny Grissom, Mariaelena Roman Sotelo, Melanie Sowards, Lilian Calisto, Christopher J Destache, Sonia Rocha-Sanchez, James C Gumbart, Helen I Zgurskaya, Mary Jackson, E Jeffrey North
Structural Determinants of Indole-2-carboxamides: Identification of Lead Acetamides with Pan Antimycobacterial Activity. Journal of medicinal chemistry 66 (1) (2022)
Pankaj Bhattarai, Pooja Hegde, Wei Li, Pavan Kumar Prathipati, Casey M Stevens, Lixinhao Yang, Hinman Zhou, Amit Pandya, Katie Cunningham, Jenny Grissom, Mariaelena Roman Sotelo, Melanie Sowards, Lilian Calisto, Christopher J Destache, Sonia Rocha-Sanchez, James C Gumbart, Helen I Zgurskaya, Mary Jackson, E Jeffrey North
Structural Determinants of Indole-2-carboxamides: Identification of Lead Acetamides with Pan Antimycobacterial Activity. Journal of medicinal chemistry 66 (1) (2022)
Pankaj Bhattarai, Pooja Hegde, Wei Li, Pavan Kumar Prathipati, Casey M Stevens, Lixinhao Yang, Hinman Zhou, Amit Pandya, Katie Cunningham, Jenny Grissom, Mariaelena Roman Sotelo, Melanie Sowards, Lilian Calisto, Christopher J Destache, Sonia Rocha-Sanchez, James C Gumbart, Helen I Zgurskaya, Mary Jackson, E Jeffrey North
Structural Determinants of Indole-2-carboxamides: Identification of Lead Acetamides with Pan Antimycobacterial Activity. Journal of medicinal chemistry 66 (1) (2022)
Pankaj Bhattarai, Pooja Hegde, Wei Li, Pavan Kumar Prathipati, Casey M Stevens, Lixinhao Yang, Hinman Zhou, Amit Pandya, Katie Cunningham, Jenny Grissom, Mariaelena Roman Sotelo, Melanie Sowards, Lilian Calisto, Christopher J Destache, Sonia Rocha-Sanchez, James C Gumbart, Helen I Zgurskaya, Mary Jackson, E Jeffrey North
Structural Determinants of Indole-2-carboxamides: Identification of Lead Acetamides with Pan Antimycobacterial Activity. Journal of medicinal chemistry (2022)
Casey M Stevens, Svitlana O Babii, Amitkumar N Pandya, Wei Li, Yupeng Li, Jitender Mehla, Robyn Scott, Pooja Hegde, Pavan Kumar Prathipati, Atanu Acharya, Jinchan Liu, James C Gumbart, Jeffrey North, Mary Jackson, Helen I Zgurskaya
Proton transfer activity of the reconstituted Mycobacterium tuberculosis MmpL3 is modulated by substrate mimics and inhibitors. Proceedings of the National Academy of Sciences of the United States of America 119 (30) (2022)
Ziwei Hu, Inga V Leus, Brinda Chandar, Bradley S Sherborne, Quentin P Avila, Valentin V Rybenkov, Helen I Zgurskaya, Adam S Duerfeldt
Structure-Uptake Relationship Studies of Oxazolidinones in Gram-Negative ESKAPE Pathogens. Journal of medicinal chemistry 65 (20) (2022)
Pankaj Bhattarai, Pooja Hegde, Wei Li, Pavan Kumar Prathipati, Casey M Stevens, Lixinhao Yang, Hinman Zhou, Amit Pandya, Katie Cunningham, Jenny Grissom, Mariaelena Roman Sotelo, Melanie Sowards, Lilian Calisto, Christopher J Destache, Sonia Rocha-Sanchez, James C Gumbart, Helen I Zgurskaya, Mary Jackson, E Jeffrey North
Structural Determinants of Indole-2-carboxamides: Identification of Lead Acetamides with Pan Antimycobacterial Activity. Journal of medicinal chemistry 66 (1) (2022)
Pedro D Manrique, Cesar A López, S Gnanakaran, Valentin V Rybenkov, Helen I Zgurskaya
New understanding of multidrug efflux and permeation in antibiotic resistance, persistence, and heteroresistance. Annals of the New York Academy of Sciences (2022)
Helen I Zgurskaya
An Old Problem in a New Light: Antibiotic Permeation Barriers. ACS infectious diseases 6 (12) (2021)
Valentin V Rybenkov, Helen I Zgurskaya, Chhandosee Ganguly, Inga V Leus, Zhen Zhang, Mohammad Moniruzzaman
The Whole Is Bigger than the Sum of Its Parts: Drug Transport in the Context of Two Membranes with Active Efflux. Chemical reviews 121 (9) (2021)
Jitender Mehla, Giuliano Malloci, Rachael Mansbach, Cesar A López, Ruslan Tsivkovski, Keith Haynes, Inga V Leus, Sally B Grindstaff, Robert H Cascella, Napoleon D'Cunha, Liam Herndon, Nicolas W Hengartner, Enrico Margiotta, Alessio Atzori, Attilio Vittorio Vargiu, Pedro D Manrique, John K Walker, Olga Lomovskaya, Paolo Ruggerone, S Gnanakaran, Valentin V Rybenkov, Helen I Zgurskaya
Predictive Rules of Efflux Inhibition and Avoidance in Pseudomonas aeruginosa. mBio 12 (1) (2021)
Helen I Zgurskaya, John K Walker, Jerry M Parks, Valentin V Rybenkov
Multidrug Efflux Pumps and the Two-Faced Janus of Substrates and Inhibitors. Accounts of chemical research 54 (4) (2021)
Justyna W Adamiak, Varsha Jhawar, Vincent Bonifay, Courtney E Chandler, Inga V Leus, Robert K Ernst, Herbert P Schweizer, Helen I Zgurskaya
Loss of RND-Type Multidrug Efflux Pumps Triggers Iron Starvation and Lipid A Modifications in Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy 65 (10) (2021)
Helen I Zgurskaya
Introduction: Transporters, Porins, and Efflux Pumps. Chemical reviews 121 (9) (2021)
Napoleon D'Cunha, Mohammad Moniruzzaman, Keith Haynes, Giuliano Malloci, Connor J Cooper, Enrico Margiotta, Attilio Vittorio Vargiu, Muhammad R Uddin, Inga V Leus, Feng Cao, Jerry M Parks, Valentin V Rybenkov, Paolo Ruggerone, Helen I Zgurskaya, John K Walker
Mechanistic Duality of Bacterial Efflux Substrates and Inhibitors: Example of Simple Substituted Cinnamoyl and Naphthyl Amides. ACS infectious diseases 7 (9) (2021)
Paramita Saha, Samapan Sikdar, Ganesh Krishnamoorthy, Helen I Zgurskaya, Valentin V Rybenkov
Drug Permeation against Efflux by Two Transporters. ACS infectious diseases 6 (4) (2020)
Inga V Leus, Justyna Adamiak, Anhthu N Trinh, Richard D Smith, Lauren Smith, Sophie Richardson, Robert K Ernst, Helen I Zgurskaya
Inactivation of AdeABC and AdeIJK efflux pumps elicits specific nonoverlapping transcriptional and phenotypic responses in Acinetobacter baumannii. Molecular microbiology 114 (6) (2020)
Mary Jackson, Casey M Stevens, Lei Zhang, Helen I Zgurskaya, Michael Niederweis
Transporters Involved in the Biogenesis and Functionalization of the Mycobacterial Cell Envelope. Chemical reviews 121 (9) (2020)
Rachael A Mansbach, Inga V Leus, Jitender Mehla, Cesar A Lopez, John K Walker, Valentin V Rybenkov, Nicolas W Hengartner, Helen I Zgurskaya, S Gnanakaran
Machine Learning Algorithm Identifies an Antibiotic Vocabulary for Permeating Gram-Negative Bacteria. Journal of chemical information and modeling 60 (6) (2020)
Shibin Zhao, Justyna W Adamiak, Vincent Bonifay, Jitender Mehla, Helen I Zgurskaya, Derek S Tan
Defining new chemical space for drug penetration into Gram-negative bacteria. Nature chemical biology 16 (12) (2020)
Wei Li, Casey M Stevens, Amitkumar N Pandya, Zbigniew Darzynkiewicz, Pankaj Bhattarai, Weiwei Tong, Mercedes Gonzalez-Juarrero, E Jeffrey North, Helen I Zgurskaya, Mary Jackson
Direct Inhibition of MmpL3 by Novel Antitubercular Compounds. ACS infectious diseases 5 (6) (2019)
Helen I Zgurskaya, Valentin V Rybenkov
Permeability barriers of Gram-negative pathogens. Annals of the New York Academy of Sciences 1459 (1) (2019)
Anthony J Hazel, Narges Abdali, Inga V Leus, Jerry M Parks, Micholas D Smith, Helen I Zgurskaya, James C Gumbart
Conformational Dynamics of AcrA Govern Multidrug Efflux Pump Assembly. ACS infectious diseases 5 (11) (2019)
Connor J Cooper, Ganesh Krishnamoorthy, David Wolloscheck, John K Walker, Valentin V Rybenkov, Jerry M Parks, Helen I Zgurskaya
Molecular Properties That Define the Activities of Antibiotics in Escherichia coli and Pseudomonas aeruginosa. ACS infectious diseases 4 (8) (2018)
Hang Zhao, Zoya M Petrushenko, John K Walker, Jerome Y Baudry, Helen I Zgurskaya, Valentin V Rybenkov
Small Molecule Condensin Inhibitors. ACS infectious diseases 4 (12) (2018)
Zhi Yue, Wei Chen, Helen I Zgurskaya, Jana Shen
Constant pH Molecular Dynamics Reveals How Proton Release Drives the Conformational Transition of a Transmembrane Efflux Pump. Journal of chemical theory and computation 13 (12) (2017)
David Wolloscheck, Ganesh Krishnamoorthy, Jennifer Nguyen, Helen I Zgurskaya
Kinetic Control of Quorum Sensing in Pseudomonas aeruginosa by Multidrug Efflux Pumps. ACS infectious diseases 4 (2) (2017)