Frank Sobott

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 52

Top Venues

Journal of the American Society for Mass Spectrometry

Science advances

Journal of the American Chemical Society

Nature communications

University of Leeds

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Leeds Feb 01 2017

United Kingdom

Chair of Biomolecular Mass Spectrometry :: School of Molecular and Cellular Biology/Astbury Centre

University of Antwerp Nov 01 2009 - Jan 31 2017

Belgium

Professor of Biomolecular and Analytical Mass Spectrometry :: Chemistry

University of Oxford Nov 01 2004 - Oct 31 2009

United Kingdom

Team Leader, Senior Scientist, PI :: Structural Genomics Consortium, Chemistry, DPAG/Oxion, Biochemistry

University of Cambridge Oct 01 2001 - Oct 31 2004

United Kingdom

PDRA (Carol V Robinson) :: Chemistry

University of Oxford Aug 01 2000 - Sep 30 2001

United Kingdom

PDRA (Carol V Robinson) :: Chemistry/OCMS

Publications

Roos Van Elzen, Albert Konijnenberg, Pieter Van Der Veken, Matthew J Edgeworth, James H Scrivens, Vilmos Fülöp, Frank Sobott, Anne-Marie Lambeir
Study of the Conformational Dynamics of Prolyl Oligopeptidase by Mass Spectrometry: Lessons Learned. Journal of medicinal chemistry 67 (12) (2024)
Roos Van Elzen, Albert Konijnenberg, Pieter Van Der Veken, Matthew J Edgeworth, James H Scrivens, Vilmos Fülöp, Frank Sobott, Anne-Marie Lambeir
Study of the Conformational Dynamics of Prolyl Oligopeptidase by Mass Spectrometry: Lessons Learned. Journal of medicinal chemistry 67 (12) (2024)
Kyle I P Le Huray, Tobias P Wörner, Tiago Moreira, Marcin Dembek, Maria Reinhardt-Szyba, Paul W A Devine, Nicholas J Bond, Kyle L Fort, Alexander A Makarov, Frank Sobott
To 200,000 m / z and Beyond: Native Electron Capture Charge Reduction Mass Spectrometry Deconvolves Heterogeneous Signals in Large Biopharmaceutical Analytes. ACS central science 10 (8) (2024)
Roos Van Elzen, Albert Konijnenberg, Pieter Van Der Veken, Matthew J Edgeworth, James H Scrivens, Vilmos Fülöp, Frank Sobott, Anne-Marie Lambeir
Study of the Conformational Dynamics of Prolyl Oligopeptidase by Mass Spectrometry: Lessons Learned. Journal of medicinal chemistry 67 (12) (2024)
Gabriela Garcia Rodriguez, Yana Girardin, Ranjan Kumar Singh, Alexander N Volkov, Jeroen F van Dyck, Gopinath Muruganandam, Frank Sobott, Daniel Charlier, Remy Loris
Toxin:antitoxin ratio sensing autoregulation of the Vibrio cholerae parDE2 module. Science advances 10 (1) (2024)
Gabriela Garcia Rodriguez, Yana Girardin, Ranjan Kumar Singh, Alexander N Volkov, Jeroen F van Dyck, Gopinath Muruganandam, Frank Sobott, Daniel Charlier, Remy Loris
Toxin:antitoxin ratio sensing autoregulation of the Vibrio cholerae parDE2 module. Science advances 10 (1) (2024)
Jaime Santos, Jorge Cuellar, Irantzu Pallarès, Emily J Byrd, Alons Lends, Fernando Moro, Muhammed Bilal Abdul-Shukkoor, Jordi Pujols, Lorea Velasco-Carneros, Frank Sobott, Daniel Erik Otzen, Antonio N Calabrese, Arturo Muga, Jan Skov Pedersen, Antoine Loquet, Jose María Valpuesta, Sheena E Radford, Salvador Ventura
A Targetable N-Terminal Motif Orchestrates α-Synuclein Oligomer-to-Fibril Conversion. Journal of the American Chemical Society 146 (18) (2024)
Kyle I P Le Huray, Tobias P Wörner, Tiago Moreira, Marcin Dembek, Maria Reinhardt-Szyba, Paul W A Devine, Nicholas J Bond, Kyle L Fort, Alexander A Makarov, Frank Sobott
To 200,000 m / z and Beyond: Native Electron Capture Charge Reduction Mass Spectrometry Deconvolves Heterogeneous Signals in Large Biopharmaceutical Analytes. ACS central science 10 (8) (2024)
Gabriela Garcia Rodriguez, Yana Girardin, Ranjan Kumar Singh, Alexander N Volkov, Jeroen F van Dyck, Gopinath Muruganandam, Frank Sobott, Daniel Charlier, Remy Loris
Toxin:antitoxin ratio sensing autoregulation of the Vibrio cholerae parDE2 module. Science advances 10 (1) (2024)
Gabriela Garcia Rodriguez, Yana Girardin, Ranjan Kumar Singh, Alexander N Volkov, Jeroen F van Dyck, Gopinath Muruganandam, Frank Sobott, Daniel Charlier, Remy Loris
Toxin:antitoxin ratio sensing autoregulation of the Vibrio cholerae parDE2 module. Science advances 10 (1) (2024)
Jaime Santos, Jorge Cuellar, Irantzu Pallarès, Emily J Byrd, Alons Lends, Fernando Moro, Muhammed Bilal Abdul-Shukkoor, Jordi Pujols, Lorea Velasco-Carneros, Frank Sobott, Daniel Erik Otzen, Antonio N Calabrese, Arturo Muga, Jan Skov Pedersen, Antoine Loquet, Jose María Valpuesta, Sheena E Radford, Salvador Ventura
A Targetable N-Terminal Motif Orchestrates α-Synuclein Oligomer-to-Fibril Conversion. Journal of the American Chemical Society 146 (18) (2024)
Jaime Santos, Jorge Cuellar, Irantzu Pallarès, Emily J Byrd, Alons Lends, Fernando Moro, Muhammed Bilal Abdul-Shukkoor, Jordi Pujols, Lorea Velasco-Carneros, Frank Sobott, Daniel Erik Otzen, Antonio N Calabrese, Arturo Muga, Jan Skov Pedersen, Antoine Loquet, Jose María Valpuesta, Sheena E Radford, Salvador Ventura
A Targetable N-Terminal Motif Orchestrates α-Synuclein Oligomer-to-Fibril Conversion. Journal of the American Chemical Society 146 (18) (2024)
Roos Van Elzen, Albert Konijnenberg, Pieter Van Der Veken, Matthew J Edgeworth, James H Scrivens, Vilmos Fülöp, Frank Sobott, Anne-Marie Lambeir
Study of the Conformational Dynamics of Prolyl Oligopeptidase by Mass Spectrometry: Lessons Learned. Journal of medicinal chemistry 67 (12) (2024)
Jaime Santos, Jorge Cuellar, Irantzu Pallarès, Emily J Byrd, Alons Lends, Fernando Moro, Muhammed Bilal Abdul-Shukkoor, Jordi Pujols, Lorea Velasco-Carneros, Frank Sobott, Daniel Erik Otzen, Antonio N Calabrese, Arturo Muga, Jan Skov Pedersen, Antoine Loquet, Jose María Valpuesta, Sheena E Radford, Salvador Ventura
A Targetable N-Terminal Motif Orchestrates α-Synuclein Oligomer-to-Fibril Conversion. Journal of the American Chemical Society (2024)
Jaime Santos, Jorge Cuellar, Irantzu Pallarès, Emily J Byrd, Alons Lends, Fernando Moro, Muhammed Bilal Abdul-Shukkoor, Jordi Pujols, Lorea Velasco-Carneros, Frank Sobott, Daniel Erik Otzen, Antonio N Calabrese, Arturo Muga, Jan Skov Pedersen, Antoine Loquet, Jose María Valpuesta, Sheena E Radford, Salvador Ventura
A Targetable N-Terminal Motif Orchestrates α-Synuclein Oligomer-to-Fibril Conversion. Journal of the American Chemical Society 146 (18) (2024)
Roos Van Elzen, Albert Konijnenberg, Pieter Van Der Veken, Matthew J Edgeworth, James H Scrivens, Vilmos Fülöp, Frank Sobott, Anne-Marie Lambeir
Study of the Conformational Dynamics of Prolyl Oligopeptidase by Mass Spectrometry: Lessons Learned. Journal of medicinal chemistry (2024)
Benjamin Russell Lewis, Muhammad R Uddin, Mohammad Moniruzzaman, Katie M Kuo, Anna J Higgins, Laila M N Shah, Frank Sobott, Jerry M Parks, Dietmar Hammerschmid, James C Gumbart, Helen I Zgurskaya, Eamonn Reading
Conformational restriction shapes the inhibition of a multidrug efflux adaptor protein. Nature communications 14 (1) (2023)
Emily J Byrd, Martin Wilkinson, Sheena E Radford, Frank Sobott
Taking Charge: Metal Ions Accelerate Amyloid Aggregation in Sequence Variants of α-Synuclein. Journal of the American Society for Mass Spectrometry 34 (3) (2023)
Emily J Byrd, Martin Wilkinson, Sheena E Radford, Frank Sobott
Taking Charge: Metal Ions Accelerate Amyloid Aggregation in Sequence Variants of α-Synuclein. Journal of the American Society for Mass Spectrometry 34 (3) (2023)
Emily J Byrd, Martin Wilkinson, Sheena E Radford, Frank Sobott
Taking Charge: Metal Ions Accelerate Amyloid Aggregation in Sequence Variants of α-Synuclein. Journal of the American Society for Mass Spectrometry 34 (3) (2023)
Emily J Byrd, Martin Wilkinson, Sheena E Radford, Frank Sobott
Taking Charge: Metal Ions Accelerate Amyloid Aggregation in Sequence Variants of α-Synuclein. Journal of the American Society for Mass Spectrometry (2023)
Emily J Byrd, Martin Wilkinson, Sheena E Radford, Frank Sobott
Taking Charge: Metal Ions Accelerate Amyloid Aggregation in Sequence Variants of α-Synuclein. Journal of the American Society for Mass Spectrometry (2023)
Emily J Byrd, Martin Wilkinson, Sheena E Radford, Frank Sobott
Taking Charge: Metal Ions Accelerate Amyloid Aggregation in Sequence Variants of α-Synuclein. Journal of the American Society for Mass Spectrometry 34 (3) (2023)
Amberley D Stephens, Johanna Kölbel, Rani Moons, Chyi Wei Chung, Michael T Ruggiero, Najet Mahmoudi, Talia A Shmool, Thomas M McCoy, Daniel Nietlispach, Alexander F Routh, Frank Sobott, J Axel Zeitler, Gabriele S Kaminski Schierle
Decreased Water Mobility Contributes To Increased α-Synuclein Aggregation. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 135 (7) (2023)
Amberley D Stephens, Johanna Kölbel, Rani Moons, Chyi Wei Chung, Michael T Ruggiero, Najet Mahmoudi, Talia A Shmool, Thomas M McCoy, Daniel Nietlispach, Alexander F Routh, Frank Sobott, J Axel Zeitler, Gabriele S Kaminski Schierle
Decreased Water Mobility Contributes To Increased α-Synuclein Aggregation. Angewandte Chemie (Weinheim an der Bergstrasse, Germany) 135 (7) (2023)
Emily J Byrd, Martin Wilkinson, Sheena E Radford, Frank Sobott
Taking Charge: Metal Ions Accelerate Amyloid Aggregation in Sequence Variants of α-Synuclein. Journal of the American Society for Mass Spectrometry 34 (3) (2023)
Emily J Byrd, Martin Wilkinson, Sheena E Radford, Frank Sobott
Taking Charge: Metal Ions Accelerate Amyloid Aggregation in Sequence Variants of α-Synuclein. Journal of the American Society for Mass Spectrometry 34 (3) (2023)
Anna J Higgins, Alex J Flynn, Anaïs Marconnet, Laura J Musgrove, Vincent L G Postis, Jonathan D Lippiat, Chun-Wa Chung, Tom Ceska, Manuela Zoonens, Frank Sobott, Stephen P Muench
Author Correction: Cycloalkane-modified amphiphilic polymers provide direct extraction of membrane proteins for CryoEM analysis. Communications biology 5 (1) (2022)
Yong Xu, Roberto Maya-Martinez, Nicolas Guthertz, George R Heath, Iain W Manfield, Alexander L Breeze, Frank Sobott, Richard Foster, Sheena E Radford
Tuning the rate of aggregation of hIAPP into amyloid using small-molecule modulators of assembly. Nature communications 13 (1) (2022)
Michele Stofella, Simon P Skinner, Frank Sobott, Jeanine Houwing-Duistermaat, Emanuele Paci
High-Resolution Hydrogen-Deuterium Protection Factors from Sparse Mass Spectrometry Data Validated by Nuclear Magnetic Resonance Measurements. Journal of the American Society for Mass Spectrometry 33 (5) (2022)
Senthil T Kumar, Anne-Laure Mahul-Mellier, Ramanath Narayana Hegde, Gwladys Riviere, Rani Moons, Alain Ibáñez de Opakua, Pedro Magalhães, Iman Rostami, Sonia Donzelli, Frank Sobott, Markus Zweckstetter, Hilal A Lashuel
A NAC domain mutation (E83Q) unlocks the pathogenicity of human alpha-synuclein and recapitulates its pathological diversity. Science advances 8 (17) (2022)
Kyle I P Le Huray, He Wang, Frank Sobott, Antreas C Kalli
Systematic simulation of the interactions of pleckstrin homology domains with membranes. Science advances 8 (27) (2022)
Sabine M Ulamec, Roberto Maya Martinez, Emily J Byrd, Katherine M Dewison, Yong Xu, Leon F Willis, Frank Sobott, George R Heath, Patricija van Oosten Hawle, Vladimir L Buchman, Sheena E Radford, David J Brockwell
Single residue modulators of amyloid formation in the N-terminal P1-region of α-synuclein. Nature communications 13 (1) (2022)
Jeroen F van Dyck, Jonathan R Burns, Kyle I P Le Huray, Albert Konijnenberg, Stefan Howorka, Frank Sobott
Sizing up DNA nanostructure assembly with native mass spectrometry and ion mobility. Nature communications 13 (1) (2022)
Lorenzo Maso, Matteo Trande, Stefano Liberi, Giulia Moro, Elise Daems, Sara Linciano, Frank Sobott, Sonia Covaceuszach, Alberto Cassetta, Silvano Fasolato, Ligia Maria Moretto, Karolien De Wael, Laura Cendron, Alessandro Angelini
Unveiling the binding mode of perfluorooctanoic acid to human serum albumin. Protein science : a publication of the Protein Society 30 (4) (2021)
Inigo Urrutia-Irazabal, James R Ault, Frank Sobott, Nigel J Savery, Mark Simon Dillingham
Analysis of the PcrA-RNA polymerase complex reveals a helicase interaction motif and a role for PcrA/UvrD helicase in the suppression of R-loops. eLife 10 (2021)
David P Klebl, Howard D White, Frank Sobott, Stephen P Muench
On-grid and in-flow mixing for time-resolved cryo-EM. Acta crystallographica. Section D, Structural biology 77 (Pt 10) (2021)
Pieter De Bruyn, Maruša Prolič-Kalinšek, Alexandra Vandervelde, Milan Malfait, Yann G J Sterckx, Frank Sobott, San Hadži, Els Pardon, Jan Steyaert, Remy Loris
Nanobody-aided crystallization of the transcription regulator PaaR2 from Escherichia coli O157:H7. Acta crystallographica. Section F, Structural biology communications 77 (Pt 10) (2021)
Anna J Higgins, Alex J Flynn, Anaïs Marconnet, Laura J Musgrove, Vincent L G Postis, Jonathan D Lippiat, Chun-Wa Chung, Tom Ceska, Manuela Zoonens, Frank Sobott, Stephen P Muench
Cycloalkane-modified amphiphilic polymers provide direct extraction of membrane proteins for CryoEM analysis. Communications biology 4 (1) (2021)
Javier Lizarrondo, David P Klebl, Stephan Niebling, Marc Abella, Martin A Schroer, Haydyn D T Mertens, Katharina Veith, Roland Thuenauer, Dmitri I Svergun, Michal Skruzny, Frank Sobott, Stephen P Muench, Maria M Garcia Alai
Structure of the endocytic adaptor complex reveals the basis for efficient membrane anchoring during clathrin-mediated endocytosis. Nature communications 12 (1) (2021)
Arianna Luise, Elena De Cecco, Erika Ponzini, Martina Sollazzo, Pietro Luigi Mauri, Frank Sobott, Giuseppe Legname, Rita Grandori, Carlo Santambrogio
Profiling Dopamine-Induced Oxidized Proteoforms of β-synuclein by Top-Down Mass Spectrometry. Antioxidants (Basel, Switzerland) 10 (6) (2021)
Gabriela Garcia Rodriguez, Yana Girardin, Alexander N Volkov, Ranjan Kumar Singh, Gopinath Muruganandam, Jeroen F van Dyck, Frank Sobott, Wim Versées, Daniel Charlier, Remy Loris
Entropic pressure controls the oligomerization of the Vibrio cholerae ParD2 antitoxin. Acta crystallographica. Section D, Structural biology 77 (Pt 7) (2021)
Timothy M Allison, Perdita E Barran, Justin L P Benesch, Sarah Cianférani, Matteo T Degiacomi, Valerie Gabelica, Rita Grandori, Erik G Marklund, Thomas Menneteau, Lukasz G Migas, Argyris Politis, Michal Sharon, Frank Sobott, Konstantinos Thalassinos
Software Requirements for the Analysis and Interpretation of Native Ion Mobility Mass Spectrometry Data. Analytical chemistry 92 (16) (2020)
David P Klebl, Diana C F Monteiro, Dimitrios Kontziampasis, Florian Kopf, Frank Sobott, Howard D White, Martin Trebbin, Stephen P Muench
Sample deposition onto cryo-EM grids: from sprays to jets and back. Acta crystallographica. Section D, Structural biology 76 (Pt 4) (2020)
Fabio Bottari, Elise Daems, Anne-Mare de Vries, Pieter Van Wielendaele, Stanislav Trashin, Ronny Blust, Frank Sobott, Annemieke Madder, José C Martins, Karolien De Wael
Do Aptamers Always Bind? The Need for a Multifaceted Analytical Approach When Demonstrating Binding Affinity between Aptamer and Low Molecular Weight Compounds. Journal of the American Chemical Society 142 (46) (2020)
Gabriela Garcia Rodriguez, Ariel Talavera Perez, Albert Konijnenberg, Frank Sobott, Jan Michiels, Remy Loris
The Escherichia coli RnlA-RnlB toxin-antitoxin complex: production, characterization and crystallization. Acta crystallographica. Section F, Structural biology communications 76 (Pt 1) (2020)
Rani Moons, Renate van der Wekken-de Bruijne, Stuart Maudsley, Filip Lemière, Anne-Marie Lambeir, Frank Sobott
Effects of Detergent on α-Synuclein Structure. A Native MS-Ion Mobility Study. International journal of molecular sciences 21 (21) (2020)
Timothy M Allison, Perdita E Barran, Sarah Cianférani, Matteo T Degiacomi, Valerie Gabelica, Rita Grandori, Erik G Marklund, Thomas Menneteau, Lukasz G Migas, Argyris Politis, Michal Sharon, Frank Sobott, Konstantinos Thalassinos, Justin L P Benesch
Computational Strategies and Challenges for Using Native Ion Mobility Mass Spectrometry in Biophysics and Structural Biology. Analytical chemistry 92 (16) (2020)
Kristina Srzentić, Luca Fornelli, Yury O Tsybin, Joseph A Loo, Henrique Seckler, Jeffrey N Agar, Lissa C Anderson, Dina L Bai, Alain Beck, Jennifer S Brodbelt, Yuri E M van der Burgt, Julia Chamot-Rooke, Sneha Chatterjee, Yunqiu Chen, David James Clark, Paul O Danis, Jolene K Diedrich, Robert A D'Ippolito, Mathieu Dupré, Natalia Gasilova, Ying Ge, Young Ah Goo, David R Goodlett, Sylvester Greer, Kim F Haselmann, Lidong He, Christopher L Hendrickson, Joshua D Hinkle, Matthew V Holt, Sam Hughes, Donald F Hunt, Michael P Snyder, Anton N Kozhinov, Ziqing Lin, Christian Malosse, Alan G Marshall, Laure Menin, Robert J Millikin, Konstantin O Nagornov, Simone Nicolardi, Ljiljana Paša-Tolić, Stuart Pengelley, Neil R Quebbemann, Anja Resemann, Wendy Sandoval, Richa Sarin, Nicholas D Schmitt, Jeffrey Shabanowitz, Jared B Shaw, Michael R Shortreed, Lloyd M Smith, Frank Sobott, Detlev Suckau, Timothy Toby, Chad R Weisbrod, Norelle C Wildburger, John Yates Iii, Sung Hwan Yoon, Nicolas L Young, Mowei Zhou
Interlaboratory Study for Characterizing Monoclonal Antibodies by Top-Down and Middle-Down Mass Spectrometry. Journal of the American Society for Mass Spectrometry 31 (9) (2020)
Erika Ponzini, Antonella De Palma, Lucilla Cerboni, Antonino Natalello, Rossana Rossi, Rani Moons, Albert Konijnenberg, Joanna Narkiewicz, Giuseppe Legname, Frank Sobott, Pietro Luigi Mauri, Carlo Santambrogio, Rita Grandori
Methionine oxidation in α-synuclein inhibits its propensity for ordered secondary structure. The Journal of biological chemistry 294 (14) (2019)
Dimitrios Kontziampasis, David P Klebl, Matthew G Iadanza, Charlotte A Scarff, Florian Kopf, Frank Sobott, Diana C F Monteiro, Martin Trebbin, Stephen P Muench, Howard D White
A cryo-EM grid preparation device for time-resolved structural studies. IUCrJ 6 (Pt 6) (2019)
Ariel Talavera-Perez, Jelle Hendrix, Wim Versées, Dukas Jurėnas, Katleen Van Nerom, Niels Vandenberk, Ranjan Kumar Singh, Albert Konijnenberg, Steven De Gieter, Daniel Castro-Roa, Anders Barth, Henri De Greve, Frank Sobott, Johan Hofkens, Nikolay Zenkin, Remy Loris, Abel Garcia-Pino
Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors. Science advances 4 (3) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Frank Sobott