Hendrik Gerhardus Kruger (Kruger Hendrik Gerhardus, Hendrik G Kruger, Gert Kruger)

ResearcherID Loop profile Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 38

Top Venues

RSC advances

ACS infectious diseases

Antibiotics (Basel, Switzerland)

Angewandte Chemie (International ed. in English)

University of KwaZulu-Natal

Potchefstroom University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of KwaZulu-Natal

South Africa

Research Professor :: Pharmaceutical Chemistry

University of KwaZulu-Natal

South Africa

Lecturer/researcher :: Chemistry

University of North Texas

United States

Visiting professor :: Chemistry

Education History

Potchefstroom University

South Africa

PHD :: Chemistry

Publications

Heidi N du Preez, Johnson Lin, Glenn E M Maguire, Colleen Aldous, Hendrik Gerhardus Kruger
COVID-19 vaccine adverse events: Evaluating the pathophysiology with an emphasis on sulfur metabolism and endotheliopathy. European journal of clinical investigation (2024)
Lloyd C Chetty, Hendrik Gerhardus Kruger, Per I Arvidsson, Tricia Naicker, Thavendran Govender
Investigating the efficacy of green solvents and solvent-free conditions in hydrogen-bonding mediated organocatalyzed model reactions. RSC advances 14 (12) (2024)
Lloyd C Chetty, Hendrik Gerhardus Kruger, Per I Arvidsson, Tricia Naicker, Thavendran Govender
Investigating the efficacy of green solvents and solvent-free conditions in hydrogen-bonding mediated organocatalyzed model reactions. RSC advances 14 (12) (2024)
Lloyd C Chetty, Hendrik Gerhardus Kruger, Per I Arvidsson, Glenn E M Maguire, Thavendran Govender, Tricia Naicker
The Oxidation of Electron-Rich Arenes Using a H 2 O 2 -Proline System. ACS omega 9 (35) (2024)
Byron K Peters, Nakita Reddy, Mbongeni Shungube, Letisha Girdhari, Sooraj Baijnath, Sipho Mdanda, Lloyd Chetty, Thandokuhle Ntombela, Thilona Arumugam, Linda A Bester, Sanil D Singh, Anil Amichund Chuturgoon, Per I Arvidsson, Glenn E M Maguire, Hendrik Gerhardus Kruger, Tricia Naicker, Thavendran Govender
In Vitro and In Vivo Development of a β-Lactam-Metallo-β-Lactamase Inhibitor: Targeting Carbapenem-Resistant Enterobacterales . ACS infectious diseases 9 (3) (2023)
Mbongeni Shungube, Ayanda K Hlophe, Letisha Girdhari, Victor T Sabe, Byron B Peters, Nakita Reddy, Kehinde F Omolabi, Lloyd Chetty, Thilona Arumugam, Anil Amichund Chuturgoon, Hendrik Gerhardus Kruger, Per I Arvidsson, Hua-Li Qin, Tricia Naicker, Thavendran Govender
Synthesis and biological evaluation of novel β-lactam-metallo β-lactamase inhibitors. RSC advances 13 (28) (2023)
Byron K Peters, Nakita Reddy, Mbongeni Shungube, Letisha Girdhari, Sooraj Baijnath, Sipho Mdanda, Lloyd Chetty, Thandokuhle Ntombela, Thilona Arumugam, Linda A Bester, Sanil D Singh, Anil Amichund Chuturgoon, Per I Arvidsson, Glenn E M Maguire, Hendrik Gerhardus Kruger, Tricia Naicker, Thavendran Govender
In Vitro and In Vivo Development of a β-Lactam-Metallo-β-Lactamase Inhibitor: Targeting Carbapenem-Resistant Enterobacterales . ACS infectious diseases (2023)
Byron K Peters, Nakita Reddy, Mbongeni Shungube, Letisha Girdhari, Sooraj Baijnath, Sipho Mdanda, Lloyd Chetty, Thandokuhle Ntombela, Thilona Arumugam, Linda A Bester, Sanil D Singh, Anil Amichund Chuturgoon, Per I Arvidsson, Glenn E M Maguire, Hendrik Gerhardus Kruger, Tricia Naicker, Thavendran Govender
In Vitro and In Vivo Development of a β-Lactam-Metallo-β-Lactamase Inhibitor: Targeting Carbapenem-Resistant Enterobacterales . ACS infectious diseases 9 (3) (2023)
Nakita Reddy, Letisha Girdhari, Mbongeni Shungube, Arno Christiaan Gouws, Byron K Peters, Kamal K Rajbongshi, Sooraj Bajinath, Sipho Mdanda, Thandokuhle Ntombela, Thilona Arumugam, Linda A Bester, Sanil D Singh, Anil Amichund Chuturgoon, Per I Arvidsson, Glenn E M Maguire, Hendrik Gerhardus Kruger, Thavendran Govender, Tricia Naicker
Neutralizing Carbapenem Resistance by Co-Administering Meropenem with Novel β-Lactam-Metallo-β-Lactamase Inhibitors. Antibiotics (Basel, Switzerland) 12 (4) (2023)
Byron K Peters, Nakita Reddy, Mbongeni Shungube, Letisha Girdhari, Sooraj Baijnath, Sipho Mdanda, Lloyd Chetty, Thandokuhle Ntombela, Thilona Arumugam, Linda A Bester, Sanil D Singh, Anil Amichund Chuturgoon, Per I Arvidsson, Glenn E M Maguire, Hendrik Gerhardus Kruger, Tricia Naicker, Thavendran Govender
In Vitro and In Vivo Development of a β-Lactam-Metallo-β-Lactamase Inhibitor: Targeting Carbapenem-Resistant Enterobacterales . ACS infectious diseases 9 (3) (2023)
Byron K Peters, Nakita Reddy, Mbongeni Shungube, Letisha Girdhari, Sooraj Baijnath, Sipho Mdanda, Lloyd Chetty, Thandokuhle Ntombela, Thilona Arumugam, Linda A Bester, Sanil D Singh, Anil Amichund Chuturgoon, Per I Arvidsson, Glenn E M Maguire, Hendrik Gerhardus Kruger, Tricia Naicker, Thavendran Govender
In Vitro and In Vivo Development of a β-Lactam-Metallo-β-Lactamase Inhibitor: Targeting Carbapenem-Resistant Enterobacterales . ACS infectious diseases (2023)
Mbongeni Shungube, Ayanda K Hlophe, Letisha Girdhari, Victor T Sabe, Byron B Peters, Nakita Reddy, Kehinde F Omolabi, Lloyd Chetty, Thilona Arumugam, Anil Amichund Chuturgoon, Hendrik Gerhardus Kruger, Per I Arvidsson, Hua-Li Qin, Tricia Naicker, Thavendran Govender
Synthesis and biological evaluation of novel β-lactam-metallo β-lactamase inhibitors. RSC advances 13 (28) (2023)
Nakita Reddy, Letisha Girdhari, Mbongeni Shungube, Arno Christiaan Gouws, Byron K Peters, Kamal K Rajbongshi, Sooraj Bajinath, Sipho Mdanda, Thandokuhle Ntombela, Thilona Arumugam, Linda A Bester, Sanil D Singh, Anil Amichund Chuturgoon, Per I Arvidsson, Glenn E M Maguire, Hendrik Gerhardus Kruger, Thavendran Govender, Tricia Naicker
Neutralizing Carbapenem Resistance by Co-Administering Meropenem with Novel β-Lactam-Metallo-β-Lactamase Inhibitors. Antibiotics (Basel, Switzerland) 12 (4) (2023)
Byron K Peters, Nakita Reddy, Mbongeni Shungube, Letisha Girdhari, Sooraj Baijnath, Sipho Mdanda, Lloyd Chetty, Thandokuhle Ntombela, Thilona Arumugam, Linda A Bester, Sanil D Singh, Anil Amichund Chuturgoon, Per I Arvidsson, Glenn E M Maguire, Hendrik Gerhardus Kruger, Tricia Naicker, Thavendran Govender
In Vitro and In Vivo Development of a β-Lactam-Metallo-β-Lactamase Inhibitor: Targeting Carbapenem-Resistant Enterobacterales . ACS infectious diseases 9 (3) (2023)
Heidi N du Preez, Colleen Aldous, Hendrik Gerhardus Kruger, Johnson Lin
N-Acetylcysteine and Other Sulfur-Donors as a Preventative and Adjunct Therapy for COVID-19. Advances in pharmacological and pharmaceutical sciences 2022 (2022)
Lucas Sousa Martins, Hendrik Gerhardus Kruger, Tricia Naicker, Cláudio Nahum Alves, Jeronimo Lameira, José Rogério A Silva
Computational insights for predicting the binding and selectivity of peptidomimetic plasmepsin IV inhibitors against cathepsin D. RSC advances 13 (1) (2022)
Arno Christiaan Gouws, Hendrik Gerhardus Kruger, Olivier Gheysens, Jan Rijn Zeevaart, Thavendran Govender, Tricia Naicker, Thomas Ebenhan
Antibiotic-Derived Radiotracers for Positron Emission Tomography: Nuclear or "Unclear" Infection Imaging? Angewandte Chemie (International ed. in English) 61 (45) (2022)
Thandokuhle Ntombela, Anya Seupersad, Sibusiso B Maseko, Collins U Ibeji, Gideon Tolufashe, Siyabonga Innocent Maphumulo, Tricia Naicker, Sooraj Bajinath, Glenn E M Maguire, Thavendran Govender, Gyanu Lamichhane, Bahareh Honarparvar, Hendrik Gerhardus Kruger
Mechanistic insight on the inhibition of D, D-carboxypeptidase from Mycobacterium tuberculosis by β-lactam antibiotics: an ONIOM acylation study. Journal of biomolecular structure & dynamics (2021)
José Rogério A Silva, Hendrik Gerhardus Kruger, Fábio A Molfetta
Drug repurposing and computational modeling for discovery of inhibitors of the main protease (M pro ) of SARS-CoV-2. RSC advances 11 (38) (2021)
Heidi N du Preez, Colleen Aldous, Melvin R Hayden, Hendrik Gerhardus Kruger, Johnson Lin
Pathogenesis of COVID-19 described through the lens of an undersulfated and degraded epithelial and endothelial glycocalyx. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 36 (1) (2021)
Zainab K Sanusi, Monsurat M Lawal, Thavendran Govender, Sooraj Bajinath, Tricia Naicker, Glenn E M Maguire, Bahareh Honarparvar, Hendrik Gerhardus Kruger
Concerted hydrolysis mechanism of HIV-1 natural substrate against subtypes B and C-SA PR: insight through molecular dynamics and hybrid QM/MM studies. Physical chemistry chemical physics : PCCP 22 (4) (2020)
Sphamandla Ntshangase, Sipho Mdanda, Tricia Naicker, Hendrik Gerhardus Kruger, Sooraj Bajinath, Thavendran Govender
Spatial distribution of elvitegravir and tenofovir in rat brain tissue: Application of matrix-assisted laser desorption/ionization mass spectrometry imaging and liquid chromatography/tandem mass spectrometry. Rapid communications in mass spectrometry : RCM 33 (21) (2020)
Zainab K Sanusi, Monsurat M Lawal, Pancham Lal Gupta, Thavendran Govender, Sooraj Bajinath, Tricia Naicker, Glenn E M Maguire, Bahareh Honarparvar, Adrian E Roitberg, Hendrik Gerhardus Kruger
Exploring the concerted mechanistic pathway for HIV-1 PR-substrate revealed by umbrella sampling simulation. Journal of biomolecular structure & dynamics (2020)
Kamini Govender, Tricia Naicker, Johnson Lin, Sooraj Bajinath, Anil Amichund Chuturgoon, Naeem Sheik Abdul, Taskeen Docrat, Hendrik Gerhardus Kruger, Thavendran Govender
A novel and more efficient biosynthesis approach for human insulin production in Escherichia coli (E. coli). AMB Express 10 (1) (2020)
Lucas Sousa Martins, Jeronimo Lameira, Hendrik Gerhardus Kruger, Cláudio Nahum Alves, José Rogério A Silva
Evaluating the Performance of a Non-Bonded Cu2+ Model Including Jahn-Teller Effect into the Binding of Tyrosinase Inhibitors. International journal of molecular sciences 21 (13) (2020)
Nakita Reddy, Mbongeni Shungube, Per I Arvidsson, Sooraj Bajinath, Hendrik Gerhardus Kruger, Thavendran Govender, Tricia Naicker
A 2018-2019 patent review of metallo beta-lactamase inhibitors. Expert opinion on therapeutic patents 30 (7) (2020)
Victor T Sabe, Gideon F Tolufashe, Collins U Ibeji, Sibusiso B Maseko, Thavendran Govender, Glenn E M Maguire, Gyanu Lamichhane, Bahareh Honarparvar, Hendrik Gerhardus Kruger
Identification of potent L,D-transpeptidase 5 inhibitors for Mycobacterium tuberculosis as potential anti-TB leads: virtual screening and molecular dynamics simulations. Journal of molecular modeling 25 (11) (2019)
Collins U Ibeji, Monsurat M Lawal, Gideon F Tolufashe, Thavendran Govender, Tricia Naicker, Glenn E M Maguire, Gyanu Lamichhane, Hendrik Gerhardus Kruger, Bahareh Honarparvar
The Driving Force for the Acylation of β-Lactam Antibiotics by L,D-Transpeptidase 2: Quantum Mechanics/Molecular Mechanics (QM/MM) Study. Chemphyschem : a European journal of chemical physics and physical chemistry 20 (9) (2019)
Sipho Mdanda, Sphamandla Ntshangase, Sanil D Singh, Tricia Naicker, Hendrik Gerhardus Kruger, Sooraj Bajinath, Thavendran Govender
Mass spectrometric investigations into the brain delivery of abacavir, stavudine and didanosine in a rodent model. Xenobiotica; the fate of foreign compounds in biological systems 50 (5) (2019)
Zainab K Sanusi, Monsurat M Lawal, Thavendran Govender, Glenn E M Maguire, Bahareh Honarparvar, Hendrik Gerhardus Kruger
Theoretical Model for HIV-1 PR That Accounts for Substrate Recognition and Preferential Cleavage of Natural Substrates. The journal of physical chemistry. B 123 (30) (2019)
Sibusiso B Maseko, Eden Padayachee, Siyabonga Maphumulo, Thavendran Govender, Yasien Sayed, Glenn Maguire, Johnson Lin, Tricia Naicker, Sooraj Baijnath, Hendrik Gerhardus Kruger
Kinetic and thermodynamic characterisation of HIV-protease inhibitors against E35D↑G↑S mutant in the South African HIV-1 subtype C protease. Journal of enzyme inhibition and medicinal chemistry 34 (1) (2019)
Annapurna Pamreddy, Sooraj Baijnath, Tricia Naicker, Sphamandla Ntshangase, Sipho Mdanda, Hlengekile Lubanyana, Hendrik Gerhardus Kruger, Thavendran Govender
Bedaquiline has potential for targeting tuberculosis reservoirs in the central nervous system. RSC advances 8 (22) (2018)
Mzilikazi F Khumalo, Ekemini D Akpan, Praveen K Chinthakindi, Edikarlos M Brasil, Kamal K Rajbongshi, Maya M Makatini, Thavendran Govender, Hendrik Gerhardus Kruger, Tricia Naicker, Per I Arvidsson
Synthesis of novel 1,2,4-thiadiazinane 1,1-dioxides via three component SuFEx type reaction. RSC advances 8 (65) (2018)
Siyabonga I Maphumulo, Amit K Halder, Thavendran Govender, Sibusiso Maseko, Glenn E M Maguire, Bahareh Honarparvar, Hendrik Gerhardus Kruger
Exploring the flap dynamics of the South African HIV subtype C protease in presence of FDA-approved inhibitors: MD study. Chemical biology & drug design 92 (5) (2018)
Belin G Teklezgi, Annapurna Pamreddy, Sooraj Baijnath, Hendrik Gerhardus Kruger, Tricia Naicker, Nirmala D Gopal, Thavendran Govender
Time-dependent regional brain distribution of methadone and naltrexone in the treatment of opioid addiction. Addiction biology 24 (3) (2018)
Zeynab Fakhar, Thavendran Govender, Glenn E M Maguire, Gyanu Lamichhane, Ross C Walker, Hendrik Gerhardus Kruger, Bahareh Honarparvar
Differential flap dynamics in l,d-transpeptidase2 from mycobacterium tuberculosis revealed by molecular dynamics. Molecular bioSystems 13 (6) (2017)
Praveen K Chinthakindi, Tricia Naicker, Niranjan Thota, Thavendran Govender, Hendrik Gerhardus Kruger, Per I Arvidsson
Sulfonimidamides in Medicinal and Agricultural Chemistry. Angewandte Chemie (International ed. in English) 56 (15) (2017)
Sibusiso B Maseko, Eden Padayachee, Thavendran Govender, Yasien Sayed, Hendrik Gerhardus Kruger, Glenn E M Maguire, Johnson Lin
I36T↑T mutation in South African subtype C (C-SA) HIV-1 protease significantly alters protease-drug interactions. Biological chemistry 398 (10) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Hendrik Gerhardus Kruger (Kruger Hendrik Gerhardus, Hendrik G Kruger, Gert Kruger)