Hu Zeng

Scopus Author ID Scopus Author ID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 37

Top Venues

bioRxiv : the preprint server for biology

Research square

Science advances

ImmunoHorizons

Mayo Clinic Rochester

Nanjing University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Mayo Clinic Rochester

United States

Senior Associate Consultant I/Assistant Professor :: Rheumatology

St. Jude Children's Research Hospital

United States

Staff scientist :: Immunology

St. Jude Children's Research Hospital

United States

Postdoctoral fellow :: Immunology

RIKEN-RCAI

Japan

Specially appointed researcher

Blood Research Institute

United States

Pre-doctoral fellow

Education History

Nanjing University

China

PHD :: Molecular Biology

Publications

Hu Zeng, Xingxing Zhu, Yue Wu, Yanfeng Li, Xian Zhou, Jens Watzlawik, Yin Chen, Ariel Raybuck, Daniel Billadeau, Virginia Smith Shapiro, Wolfdieter Springer, Jie Sun, Mark Boothby
Rag-GTPase-TFEB/TFE3 axis controls B cell mitochondrial fitness and humoral immunity independent of mTORC1. Research square (2024)
Xian Zhou, Meilu Li, Minji Ai, Yanfeng Li, Xingxing Zhu, Michael J Hansen, Jun Zhong, Kenneth L Johnson, Roman Zenka, Akhilesh Pandey, Larry R Pease, Hu Zeng
PP2A catalytic subunit alpha is critically required for CD8 + T cell homeostasis and anti-bacterial responses. bioRxiv : the preprint server for biology (2024)
Xingxing Zhu, Yue Wu, Yanfeng Li, Xian Zhou, Jens O Watzlawik, Yin Maggie Chen, Ariel L Raybuck, Daniel Billadeau, Virginia Shapiro, Wolfdieter Springer, Jie Sun, Mark R Boothby, Hu Zeng
The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness. bioRxiv : the preprint server for biology (2024)
Meilu Li, Xian Zhou, Xingxing Zhu, Yanfeng Li, Taro Hitosugi, Yuzhen Li, Hu Zeng
CPT2 mediated fatty acid oxidation is dispensable for humoral immunity. bioRxiv : the preprint server for biology (2024)
Xingxing Zhu, Yue Wu, Yanfeng Li, Xian Zhou, Jens O Watzlawik, Yin Maggie Chen, Ariel L Raybuck, Daniel Billadeau, Virginia Smith Shapiro, Wolfdieter Springer, Jie Sun, Mark R Boothby, Hu Zeng
Rag-GTPase-TFEB/TFE3 axis controls B cell mitochondrial fitness and humoral immunity independent of mTORC1. Research square (2024)
Meilu Li, Xian Zhou, Xingxing Zhu, Yanfeng Li, Taro Hitosugi, Yuzhen Li, Hu Zeng
CPT2 mediated fatty acid oxidation is dispensable for humoral immunity. bioRxiv : the preprint server for biology (2024)
Xingxing Zhu, Yue Wu, Yanfeng Li, Xian Zhou, Jens O Watzlawik, Yin Maggie Chen, Ariel L Raybuck, Daniel Billadeau, Virginia Shapiro, Wolfdieter Springer, Jie Sun, Mark R Boothby, Hu Zeng
The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness. bioRxiv : the preprint server for biology (2024)
Minji Ai, Xian Zhou, Michele Carrer, Paymaan Jafar-Nejad, Yanfeng Li, Naomi Gades, Mariam P Alexander, Mario A Bautista, Ali A Duarte Garcia, Hu Zeng
Targeting mechanistic target of rapamycin complex 2 attenuates immunopathology in Systemic Lupus Erythematosus. bioRxiv : the preprint server for biology (2024)
Xian Zhou, Meilu Li, Minji Ai, Yanfeng Li, Xingxing Zhu, Michael J Hansen, Jun Zhong, Kenneth L Johnson, Roman Zenka, Akhilesh Pandey, Larry R Pease, Hu Zeng
PP2A catalytic subunit alpha is critically required for CD8 + T cell homeostasis and anti-bacterial responses. bioRxiv : the preprint server for biology (2024)
Xingxing Zhu, Yue Wu, Yanfeng Li, Xian Zhou, Jens O Watzlawik, Yin Maggie Chen, Ariel L Raybuck, Daniel Billadeau, Virginia Shapiro, Wolfdieter Springer, Jie Sun, Mark R Boothby, Hu Zeng
The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness. bioRxiv : the preprint server for biology (2024)
Xian Zhou, Meilu Li, Minji Ai, Yanfeng Li, Xingxing Zhu, Michael J Hansen, Jun Zhong, Kenneth L Johnson, Roman Zenka, Akhilesh Pandey, Larry R Pease, Hu Zeng
PP2A catalytic subunit alpha is critically required for CD8 + T cell homeostasis and anti-bacterial responses. bioRxiv : the preprint server for biology (2024)
Meilu Li, Xian Zhou, Yanfeng Li, Xingxing Zhu, Yuzhen Li, Taro Hitosugi, Hu Zeng
CPT2-mediated Fatty Acid Oxidation Is Dispensable for Humoral Immunity. Journal of immunology (Baltimore, Md. : 1950) (2024)
Meilu Li, Xian Zhou, Xingxing Zhu, Yanfeng Li, Taro Hitosugi, Yuzhen Li, Hu Zeng
CPT2 mediated fatty acid oxidation is dispensable for humoral immunity. bioRxiv : the preprint server for biology (2024)
Xingxing Zhu, Yue Wu, Yanfeng Li, Xian Zhou, Jens O Watzlawik, Yin Maggie Chen, Ariel L Raybuck, Daniel Billadeau, Virginia Shapiro, Wolfdieter Springer, Jie Sun, Mark R Boothby, Hu Zeng
The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness. bioRxiv : the preprint server for biology (2024)
Hu Zeng, Xingxing Zhu, Yue Wu, Yanfeng Li, Xian Zhou, Jens Watzlawik, Yin Chen, Ariel Raybuck, Daniel Billadeau, Virginia Smith Shapiro, Wolfdieter Springer, Jie Sun, Mark Boothby
Rag-GTPase-TFEB/TFE3 axis controls B cell mitochondrial fitness and humoral immunity independent of mTORC1. Research square (2024)
Xian Zhou, Meilu Li, Minji Ai, Yanfeng Li, Xingxing Zhu, Michael J Hansen, Jun Zhong, Kenneth L Johnson, Roman Zenka, Akhilesh Pandey, Larry R Pease, Hu Zeng
PP2A catalytic subunit alpha is critically required for CD8 + T cell homeostasis and anti-bacterial responses. bioRxiv : the preprint server for biology (2024)
Xingxing Zhu, Yue Wu, Yanfeng Li, Xian Zhou, Jens O Watzlawik, Yin Maggie Chen, Ariel L Raybuck, Daniel Billadeau, Virginia Smith Shapiro, Wolfdieter Springer, Jie Sun, Mark R Boothby, Hu Zeng
Rag-GTPase-TFEB/TFE3 axis controls B cell mitochondrial fitness and humoral immunity independent of mTORC1. Research square (2024)
Xian Zhou, Meilu Li, Minji Ai, Yanfeng Li, Xingxing Zhu, Michael J Hansen, Jun Zhong, Kenneth L Johnson, Roman Zenka, Akhilesh Pandey, Larry R Pease, Hu Zeng
PP2A catalytic subunit alpha is critically required for CD8 + T-cell homeostasis and antibacterial responses. European journal of immunology (2024)
Xingxing Zhu, Yue Wu, Yanfeng Li, Xian Zhou, Jens O Watzlawik, Yin Maggie Chen, Ariel L Raybuck, Daniel Billadeau, Virginia Shapiro, Wolfdieter Springer, Jie Sun, Mark R Boothby, Hu Zeng
The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness. bioRxiv : the preprint server for biology (2024)
Xingxing Zhu, Yue Wu, Yanfeng Li, Xian Zhou, Jens O Watzlawik, Yin Maggie Chen, Ariel L Raybuck, Daniel Billadeau, Virginia Shapiro, Wolfdieter Springer, Jie Sun, Mark R Boothby, Hu Zeng
The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness. bioRxiv : the preprint server for biology (2024)
Xian Zhou, Meilu Li, Minji Ai, Yanfeng Li, Xingxing Zhu, Michael J Hansen, Jun Zhong, Kenneth L Johnson, Roman Zenka, Akhilesh Pandey, Larry R Pease, Hu Zeng
PP2A catalytic subunit alpha is critically required for CD8 + T-cell homeostasis and antibacterial responses. European journal of immunology (2024)
Minji Ai, Xian Zhou, Michele Carrer, Paymaan Jafar-Nejad, Yanfeng Li, Naomi Gades D V M, Mariam P Alexander, Mario A Bautista, Ali A Duarte Garcia, Hu Zeng
Targeting mechanistic target of rapamycin complex 2 attenuates immunopathology in Systemic Lupus Erythematosus. bioRxiv : the preprint server for biology (2024)
Whitney Barham, Michelle Hsu, Xin Liu, Susan M Harrington, Jacob B Hirdler, Joanina K Gicobi, Xingxing Zhu, Hu Zeng, Kevin D Pavelko, Yiyi Yan, Aaron S Mansfield, Haidong Dong
A Novel Humanized PD-1/PD-L1 Mouse Model Permits Direct Comparison of Antitumor Immunity Generated by Food and Drug Administration-Approved PD-1 and PD-L1 Inhibitors. ImmunoHorizons 7 (1) (2023)
Joanina K Gicobi, Zhiming Mao, Grace DeFranco, Jacob B Hirdler, Ying Li, Vianca V Vianzon, Emilia R Dellacecca, Michelle A Hsu, Whitney Barham, Yiyi Yan, Aaron S Mansfield, Yi Lin, Xiaosheng Wu, Taro Hitosugi, Dawn Owen, Michael P Grams, Jacob J Orme, Fabrice Lucien, Hu Zeng, Sean S Park, Haidong Dong
Salvage therapy expands highly cytotoxic and metabolically fit resilient CD8 + T cells via ME1 up-regulation. Science advances 9 (46) (2023)
Zesheng An, Xian Zhou, Yanfeng Li, Jane Jaquith, Kathleen McCarthy-Fruin, Jennifer Sletten, Kenneth J Warrington, Cornelia Weyand, Cynthia S Crowson, Saranya Chumsri, Keith L Knutson, Gabriel Figueroa-Parra, Alain Sanchez-Rodriguez, Uma Thanarajasingam, Alí Duarte-García, Hu Zeng
Immune responses and disease biomarker long-term changes following COVID-19 mRNA vaccination in a cohort of rheumatic disease patients. medRxiv : the preprint server for health sciences (2023)
Whitney Barham, Michelle Hsu, Xin Liu, Susan M Harrington, Jacob B Hirdler, Joanina K Gicobi, Xingxing Zhu, Hu Zeng, Kevin D Pavelko, Yiyi Yan, Aaron S Mansfield, Haidong Dong
A Novel Humanized PD-1/PD-L1 Mouse Model Permits Direct Comparison of Antitumor Immunity Generated by Food and Drug Administration-Approved PD-1 and PD-L1 Inhibitors. ImmunoHorizons 7 (1) (2023)
Whitney Barham, Michelle Hsu, Xin Liu, Susan M Harrington, Jacob B Hirdler, Joanina K Gicobi, Xingxing Zhu, Hu Zeng, Kevin D Pavelko, Yiyi Yan, Aaron S Mansfield, Haidong Dong
A Novel Humanized PD-1/PD-L1 Mouse Model Permits Direct Comparison of Antitumor Immunity Generated by Food and Drug Administration-Approved PD-1 and PD-L1 Inhibitors. ImmunoHorizons 7 (1) (2023)
Melissa E Munroe, Derek Blankenship, Daniele DeFreese, Mohan Purushothaman, Wade DeJager, Susan Macwana, Joel M Guthridge, Stan Kamp, Nancy Redinger, Teresa Aberle, Eliza F Chakravarty, Cristina Arriens, Yanfeng Li, Hu Zeng, Kathleen A McCarthy-Fruin, Shirley-Ann Osei-Onomahm, Uma Thanarajasingam, Judith A James, Eldon Jupe
A Flare Risk Index Informed by Select Immune Mediators in Systemic Lupus Erythematosus. Arthritis & rheumatology (Hoboken, N.J.) (2022)
Xian Zhou, Haiyu Qi, Meilu Li, Yanfeng Li, Xingxing Zhu, Shreyasee Amin, Mariam Alexander, Catherine Diadhiou, Anne Davidson, Hu Zeng
mTORC2 contributes to systemic autoimmunity. Immunology (2022)
Xian Zhou, Xingxing Zhu, Hu Zeng
Fatty acid metabolism in adaptive immunity. The FEBS journal (2021)
Yuan Liu, Jane M Jaquith, Kathleen Mccarthy-Fruin, Xingxing Zhu, Xian Zhou, Yanfeng Li, Cynthia Crowson, John M Davis, Uma Thanarajasingam, Hu Zeng
Immune checkpoint inhibitor-induced inflammatory arthritis: a novel clinical entity with striking similarities to seronegative rheumatoid arthritis. Clinical rheumatology 39 (12) (2020)
Hu Zeng, Hongbo Chi
Metabolic sleuthing solves a rare immunodeficiency disease. Nature immunology 20 (10) (2020)
Jordy Saravia, Hu Zeng, Yogesh Dhungana, Daniel Bastardo Blanco, Thanh-Long M Nguyen, Nicole M Chapman, Yanyan Wang, Apurva Kanneganti, Shaofeng Liu, Jana L Raynor, Peter Vogel, Geoffrey A Neale, Peter Carmeliet, Hongbo Chi
Homeostasis and transitional activation of regulatory T cells require c-Myc. Science advances 6 (1) (2020)
Jonathan Jung, Hu Zeng, Tiffany Horng
Metabolism as a guiding force for immunity. Nature cell biology 21 (1) (2019)
Hu Zeng, Mei Yu, Haiyan Tan, Yuxin Li, Wei Su, Hao Shi, Yogesh Dhungana, Clifford S Guy, Geoffrey A Neale, Caryn Cloer, Junmin Peng, Demin Wang, Hongbo Chi
Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis. Science advances 4 (1) (2018)
Nicole M Chapman, Hu Zeng, Thanh-Long M Nguyen, Yanyan Wang, Peter Vogel, Yogesh Dhungana, Xiaojing Liu, Geoffrey A Neale, Jason W Locasale, Hongbo Chi
mTOR coordinates transcriptional programs and mitochondrial metabolism of activated Treg subsets to protect tissue homeostasis. Nature communications 9 (1) (2018)
Mei Yu, Yuhong Chen, Hu Zeng, Yongwei Zheng, Guoping Fu, Wen Zhu, Ulrich Broeckel, Praful Aggarwal, Amy Turner, Geoffrey A Neale, Cliff Guy, Nan Zhu, Hongbo Chi, Renren Wen, Demin Wang
PLCγ-dependent mTOR signalling controls IL-7-mediated early B cell development. Nature communications 8 (1) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Hu Zeng