Huaiyu Yang

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 22

Top Topics

Molecular Dynamics Simulations

Neuropathic Pain

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Nature chemical biology

Journal of medicinal chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Huajian Lin, Junnan Li, Qiansen Zhang, Huaiyu Yang, Shanshuang Chen
C-type inactivation and proton modulation mechanisms of the TASK3 channel. Proceedings of the National Academy of Sciences of the United States of America 121 (17) (2024)
Huajian Lin, Junnan Li, Qiansen Zhang, Huaiyu Yang, Shanshuang Chen
C-type inactivation and proton modulation mechanisms of the TASK3 channel. Proceedings of the National Academy of Sciences of the United States of America 121 (17) (2024)
Huajian Lin, Junnan Li, Qiansen Zhang, Huaiyu Yang, Shanshuang Chen
C-type inactivation and proton modulation mechanisms of the TASK3 channel. Proceedings of the National Academy of Sciences of the United States of America 121 (17) (2024)
Huajian Lin, Junnan Li, Qiansen Zhang, Huaiyu Yang, Shanshuang Chen
C-type inactivation and proton modulation mechanisms of the TASK3 channel. Proceedings of the National Academy of Sciences of the United States of America 121 (17) (2024)
Huajian Lin, Junnan Li, Qiansen Zhang, Huaiyu Yang, Shanshuang Chen
C-type inactivation and proton modulation mechanisms of the TASK3 channel. Proceedings of the National Academy of Sciences of the United States of America 121 (17) (2024)
Shaoying Zhang, Demin Ma, Kun Wang, Ya Li, Zhenni Yang, Xiaoxiao Li, Junnan Li, Jiangnan He, Lianghe Mei, Yangliang Ye, Zongsheng Chen, Juwen Shen, Panpan Hou, Jiang Tao Guo, Qiansen Zhang, Huaiyu Yang
A small-molecule activation mechanism that directly opens the KCNQ2 channel. Nature chemical biology 20 (7) (2024)
Ling Zhong, Zhenzhen Yan, Dexiang Jiang, Kuo-Chan Weng, Yue Ouyang, Hangyu Zhang, Xiaoqing Lin, Chenxin Xiao, Huaiyu Yang, Jing Yao, Xinjiang Kang, Changhe Wang, Chen Huang, Bing Shen, Sookja Kim Chung, Zhi-Hong Jiang, Wandi Zhu, Erwin Neher, Jonathan R Silva, Panpan Hou
Targeting the I Ks Channel PKA Phosphorylation Axis to Restore Its Function in High-Risk LQT1 Variants. Circulation research (2024)
Shaoying Zhang, Demin Ma, Kun Wang, Ya Li, Zhenni Yang, Xiaoxiao Li, Junnan Li, Jiangnan He, Lianghe Mei, Yangliang Ye, Zongsheng Chen, Juwen Shen, Panpan Hou, Jiang Tao Guo, Qiansen Zhang, Huaiyu Yang
A small-molecule activation mechanism that directly opens the KCNQ2 channel. Nature chemical biology (2024)
Shaoying Zhang, Demin Ma, Kun Wang, Ya Li, Zhenni Yang, Xiaoxiao Li, Junnan Li, Jiangnan He, Lianghe Mei, Yangliang Ye, Zongsheng Chen, Juwen Shen, Panpan Hou, Jiang Tao Guo, Qiansen Zhang, Huaiyu Yang
A small-molecule activation mechanism that directly opens the KCNQ2 channel. Nature chemical biology (2024)
Shaoying Zhang, Demin Ma, Kun Wang, Ya Li, Zhenni Yang, Xiaoxiao Li, Junnan Li, Jiangnan He, Lianghe Mei, Yangliang Ye, Zongsheng Chen, Juwen Shen, Panpan Hou, Jiang Tao Guo, Qiansen Zhang, Huaiyu Yang
A small-molecule activation mechanism that directly opens the KCNQ2 channel. Nature chemical biology 20 (7) (2024)
Shijie Liu, Peipei Guo, Kun Wang, Shaoying Zhang, Ya Li, Juwen Shen, Lianghe Mei, Yangliang Ye, Qiansen Zhang, Huaiyu Yang
General Pharmacological Activation Mechanism of K + Channels Bypassing Channel Gates. Journal of medicinal chemistry 65 (15) (2022)
Xiangyi Wen, Ping Liao, Yuncheng Luo, Linghui Yang, Huaiyu Yang, Longqian Liu, Ruo-Tian Jiang
Tandem pore domain acid-sensitive K channel 3 (TASK-3) regulates visual sensitivity in healthy and aging retina. Science advances 8 (36) (2022)
Qiansen Zhang, Yimin Ren, Yiqing Mo, Peipei Guo, Ping Liao, Yuncheng Luo, Jie Mu, Zhuo Chen, Yang Zhang, Ya Li, Linghui Yang, Daqing Liao, Jie Fu, Juwen Shen, Wei Huang, Xuewen Xu, Yanyan Guo, Lianghe Mei, Yunxia Zuo, Jin Liu, Huaiyu Yang, Ruo-Tian Jiang
Inhibiting Hv1 channel in peripheral sensory neurons attenuates chronic inflammatory pain and opioid side effects. Cell research 32 (5) (2022)
Jiang Wang, Dehua Yang, Xi Cheng, Linlin Yang, Zhaohui Wang, Antao Dai, Xiaoqing Cai, Chao Zhang, Elita Yuliantie, Qiaofeng Liu, Hualiang Jiang, Hong Liu, Ming-Wei Wang, Huaiyu Yang
Allosteric Modulators Enhancing GLP-1 Binding to GLP-1R via a Transmembrane Site. ACS chemical biology 16 (11) (2021)
Feng Tang, Mang Zhou, Ken Qin, Wei Shi, Ansor Yashinov, Yang Yang, Liyun Yang, Dongliang Guan, Lei Zhao, Yubo Tang, Yujie Chang, Lifen Zhao, Huaiyu Yang, Hu Zhou, Ruimin Huang, Wei Huang
Selective N-glycan editing on living cell surfaces to probe glycoconjugate function. Nature chemical biology 16 (7) (2020)
Huiying Li, Qiansen Zhang, Yiran Gu, Yingyin Wu, Yamei Wang, Liren Wang, Shijie Feng, Yaqiang Hu, Yansen Zheng, Yongmei Li, Haifeng Ye, Bin Zhou, Longnian Lin, Mingyao Liu, Huaiyu Yang, Dali Li
Efficient photoactivatable Dre recombinase for cell type-specific spatiotemporal control of genome engineering in the mouse. Proceedings of the National Academy of Sciences of the United States of America 117 (52) (2020)
Yuqin Ma, Qichao Luo, Jie Fu, Yanxin Che, Fei Guo, Lianghe Mei, Qiansen Zhang, Yang Li, Huaiyu Yang
Discovery of an Inhibitor for the TREK-1 Channel Targeting an Intermediate Transition State of Channel Gating. Journal of medicinal chemistry 63 (19) (2020)
Ping Liao, Yunguang Qiu, Yiqing Mo, Jie Fu, Zhenpeng Song, Lu Huang, Suwen Bai, Yang Wang, Jia-Jie Zhu, Fuyun Tian, Zhuo Chen, Nanfang Pan, Er-Yi Sun, Linghui Yang, Xi Lan, Yinbin Chen, Dongping Huang, Peihua Sun, Lifen Zhao, Dehua Yang, Weiqiang Lu, Tingting Yang, Junjie Xiao, Wei-Guang Li, Zhaobing Gao, Bing Shen, Qiansen Zhang, Jin Liu, Hualiang Jiang, Ruo-Tian Jiang, Huaiyu Yang
Selective activation of TWIK-related acid-sensitive K+ 3 subunit-containing channels is analgesic in rodent models. Science translational medicine 11 (519) (2020)
Yunguang Qiu, Lu Huang, Jie Fu, Chenxia Han, Jing Fang, Ping Liao, Zhuo Chen, Yiqing Mo, Peihua Sun, Daqing Liao, Linghui Yang, Jing Wang, Qiansen Zhang, Jin Liu, Feng Liu, Tingting Liu, Wei Huang, Huaiyu Yang, Ruo-Tian Jiang
TREK Channel Family Activator with a Well-Defined Structure-Activation Relationship for Pain and Neurogenic Inflammation. Journal of medicinal chemistry 63 (7) (2020)
Hao Chai, Xi Cheng, Bin Zhou, Lifen Zhao, Xianhua Lin, Dongping Huang, Weiqiang Lu, Hao Lv, Feng Tang, Qiansen Zhang, Wei Huang, Yang Li, Huaiyu Yang
Structure-Based Discovery of a Subtype-Selective Inhibitor Targeting a Transient Receptor Potential Vanilloid Channel. Journal of medicinal chemistry 62 (3) (2019)
Qiansen Zhang, Mang Zhou, Lifen Zhao, Hualiang Jiang, Huaiyu Yang
Dynamic States of the Ligand-Free Class A G Protein-Coupled Receptor Extracellular Side. Biochemistry 57 (32) (2018)
Tao Zhang, Yunguang Qiu, Qichao Luo, Lifen Zhao, Xin Yan, Qiaoce Ding, Hualiang Jiang, Huaiyu Yang
The Mechanism by Which Luteolin Disrupts the Cytoplasmic Membrane of Methicillin-Resistant Staphylococcus aureus. The journal of physical chemistry. B 122 (4) (2018)