Qiansen Zhang

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 23

Top Topics

Molecular Dynamics Simulations

Systemic Sclerosis

Top Venues

Journal of medicinal chemistry

Proceedings of the National Academy of Sciences of the United States of America

Nature chemical biology

This page only lists publications with an associated author ORCID identifier.

Publications

Huang Chen, Aiwu Bian, Wenbo Zhou, Ying Miao, Jiangnan Ye, Jiahui Li, Peng He, Qiansen Zhang, Yue Sun, Zhenliang Sun, Chaowen Ti, Yihua Chen, Zheng-Fang Yi, Mingyao Liu
Discovery of the Highly Selective and Potent STAT3 Inhibitor for Pancreatic Cancer Treatment. ACS central science 10 (3) (2024)
Huajian Lin, Junnan Li, Qiansen Zhang, Huaiyu Yang, Shanshuang Chen
C-type inactivation and proton modulation mechanisms of the TASK3 channel. Proceedings of the National Academy of Sciences of the United States of America 121 (17) (2024)
Huajian Lin, Junnan Li, Qiansen Zhang, Huaiyu Yang, Shanshuang Chen
C-type inactivation and proton modulation mechanisms of the TASK3 channel. Proceedings of the National Academy of Sciences of the United States of America 121 (17) (2024)
Huajian Lin, Junnan Li, Qiansen Zhang, Huaiyu Yang, Shanshuang Chen
C-type inactivation and proton modulation mechanisms of the TASK3 channel. Proceedings of the National Academy of Sciences of the United States of America 121 (17) (2024)
Huajian Lin, Junnan Li, Qiansen Zhang, Huaiyu Yang, Shanshuang Chen
C-type inactivation and proton modulation mechanisms of the TASK3 channel. Proceedings of the National Academy of Sciences of the United States of America 121 (17) (2024)
Huajian Lin, Junnan Li, Qiansen Zhang, Huaiyu Yang, Shanshuang Chen
C-type inactivation and proton modulation mechanisms of the TASK3 channel. Proceedings of the National Academy of Sciences of the United States of America 121 (17) (2024)
Shaoying Zhang, Demin Ma, Kun Wang, Ya Li, Zhenni Yang, Xiaoxiao Li, Junnan Li, Jiangnan He, Lianghe Mei, Yangliang Ye, Zongsheng Chen, Juwen Shen, Panpan Hou, Jiang Tao Guo, Qiansen Zhang, Huaiyu Yang
A small-molecule activation mechanism that directly opens the KCNQ2 channel. Nature chemical biology 20 (7) (2024)
Shaoying Zhang, Demin Ma, Kun Wang, Ya Li, Zhenni Yang, Xiaoxiao Li, Junnan Li, Jiangnan He, Lianghe Mei, Yangliang Ye, Zongsheng Chen, Juwen Shen, Panpan Hou, Jiang Tao Guo, Qiansen Zhang, Huaiyu Yang
A small-molecule activation mechanism that directly opens the KCNQ2 channel. Nature chemical biology (2024)
Huang Chen, Aiwu Bian, Wenbo Zhou, Ying Miao, Jiangnan Ye, Jiahui Li, Peng He, Qiansen Zhang, Yue Sun, Zhenliang Sun, Chaowen Ti, Yihua Chen, Zheng-Fang Yi, Mingyao Liu
Discovery of the Highly Selective and Potent STAT3 Inhibitor for Pancreatic Cancer Treatment. ACS central science 10 (3) (2024)
Shaoying Zhang, Demin Ma, Kun Wang, Ya Li, Zhenni Yang, Xiaoxiao Li, Junnan Li, Jiangnan He, Lianghe Mei, Yangliang Ye, Zongsheng Chen, Juwen Shen, Panpan Hou, Jiang Tao Guo, Qiansen Zhang, Huaiyu Yang
A small-molecule activation mechanism that directly opens the KCNQ2 channel. Nature chemical biology (2024)
Shaoying Zhang, Demin Ma, Kun Wang, Ya Li, Zhenni Yang, Xiaoxiao Li, Junnan Li, Jiangnan He, Lianghe Mei, Yangliang Ye, Zongsheng Chen, Juwen Shen, Panpan Hou, Jiang Tao Guo, Qiansen Zhang, Huaiyu Yang
A small-molecule activation mechanism that directly opens the KCNQ2 channel. Nature chemical biology 20 (7) (2024)
Shijie Liu, Peipei Guo, Kun Wang, Shaoying Zhang, Ya Li, Juwen Shen, Lianghe Mei, Yangliang Ye, Qiansen Zhang, Huaiyu Yang
General Pharmacological Activation Mechanism of K + Channels Bypassing Channel Gates. Journal of medicinal chemistry 65 (15) (2022)
Wei Wang, Jiacheng He, Jun-Jie Yang, Chan Zhang, Zhiyuan Cheng, Yao Zhang, Qiansen Zhang, Pei-Li Wang, Shuowen Tang, Xin Wang, Mingyao Liu, Weiqiang Lu, Han-Kun Zhang
Scaffold Hopping Strategy to Identify Prostanoid EP4 Receptor Antagonists for Cancer Immunotherapy. Journal of medicinal chemistry 65 (11) (2022)
Huang Chen, Wenbo Zhou, Aiwu Bian, Qiansen Zhang, Ying Miao, Shifen Xu, Jiangnan Ye, Shi-Fen Xu, Chaowen Ti, Zhenliang Sun, Jianghua Zheng, Yihua Chen, Mingyao Liu, Zheng-Fang Yi
Selectively targeting STAT3 using a small molecule inhibitor is a potential therapeutic strategy for pancreatic cancer. Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Qiansen Zhang, Yimin Ren, Yiqing Mo, Peipei Guo, Ping Liao, Yuncheng Luo, Jie Mu, Zhuo Chen, Yang Zhang, Ya Li, Linghui Yang, Daqing Liao, Jie Fu, Juwen Shen, Wei Huang, Xuewen Xu, Yanyan Guo, Lianghe Mei, Yunxia Zuo, Jin Liu, Huaiyu Yang, Ruo-Tian Jiang
Inhibiting Hv1 channel in peripheral sensory neurons attenuates chronic inflammatory pain and opioid side effects. Cell research 32 (5) (2022)
Bei-Er Jiang, Xingwu Jiang, Qiansen Zhang, Qiuwen Liang, Zi-Liang Qiu, Xiang-Bai Sun, Jun-Jie Yang, Si Chen, Chunyang Yi, Xiaolei Chai, Mingyao Liu, Li-Fang Yu, Weiqiang Lu, Han-Kun Zhang
From a Designer Drug to the Discovery of Selective Cannabinoid Type 2 Receptor Agonists with Favorable Pharmacokinetic Profiles for the Treatment of Systemic Sclerosis. Journal of medicinal chemistry 64 (1) (2020)
Weikai Guo, Yajing Xing, Qiansen Zhang, Jiuqing Xie, Dongxia Huang, Haijun Gu, Peng He, Miaoran Zhou, Shi-Fen Xu, Xiufeng Pang, Mingyao Liu, Zheng-Fang Yi, Yihua Chen
Synthesis and Biological Evaluation of B-Cell Lymphoma 6 Inhibitors of N-Phenyl-4-pyrimidinamine Derivatives Bearing Potent Activities against Tumor Growth. Journal of medicinal chemistry 63 (2) (2020)
Xiaoxiao Li, Qiansen Zhang, Peipei Guo, Jie Fu, Lianghe Mei, Dashuai Lv, Jiangqin Wang, Dongwu Lai, Sheng Ye, Huaiyu Yang, Jiangtao Guo
Molecular basis for ligand activation of the human KCNQ2 channel. Cell research 31 (1) (2020)
Huiying Li, Qiansen Zhang, Yiran Gu, Yingyin Wu, Yamei Wang, Liren Wang, Shijie Feng, Yaqiang Hu, Yansen Zheng, Yongmei Li, Haifeng Ye, Bin Zhou, Longnian Lin, Mingyao Liu, Huaiyu Yang, Dali Li
Efficient photoactivatable Dre recombinase for cell type-specific spatiotemporal control of genome engineering in the mouse. Proceedings of the National Academy of Sciences of the United States of America 117 (52) (2020)
Yuqin Ma, Qichao Luo, Jie Fu, Yanxin Che, Fei Guo, Lianghe Mei, Qiansen Zhang, Yang Li, Huaiyu Yang
Discovery of an Inhibitor for the TREK-1 Channel Targeting an Intermediate Transition State of Channel Gating. Journal of medicinal chemistry 63 (19) (2020)
Ping Liao, Yunguang Qiu, Yiqing Mo, Jie Fu, Zhenpeng Song, Lu Huang, Suwen Bai, Yang Wang, Jia-Jie Zhu, Fuyun Tian, Zhuo Chen, Nanfang Pan, Er-Yi Sun, Linghui Yang, Xi Lan, Yinbin Chen, Dongping Huang, Peihua Sun, Lifen Zhao, Dehua Yang, Weiqiang Lu, Tingting Yang, Junjie Xiao, Wei-Guang Li, Zhaobing Gao, Bing Shen, Qiansen Zhang, Jin Liu, Hualiang Jiang, Ruo-Tian Jiang, Huaiyu Yang
Selective activation of TWIK-related acid-sensitive K+ 3 subunit-containing channels is analgesic in rodent models. Science translational medicine 11 (519) (2020)
Yunguang Qiu, Lu Huang, Jie Fu, Chenxia Han, Jing Fang, Ping Liao, Zhuo Chen, Yiqing Mo, Peihua Sun, Daqing Liao, Linghui Yang, Jing Wang, Qiansen Zhang, Jin Liu, Feng Liu, Tingting Liu, Wei Huang, Huaiyu Yang, Ruo-Tian Jiang
TREK Channel Family Activator with a Well-Defined Structure-Activation Relationship for Pain and Neurogenic Inflammation. Journal of medicinal chemistry 63 (7) (2020)
Jun-Jie Yang, Wei-Wei Yu, Long-Long Hu, Wen-Juan Liu, Xian-Hua Lin, Wei Wang, Qiansen Zhang, Pei-Li Wang, Shuo-Wen Tang, Xin Wang, Mingyao Liu, Weiqiang Lu, Han-Kun Zhang
Discovery and Characterization of 1H-1,2,3-Triazole Derivatives as Novel Prostanoid EP4 Receptor Antagonists for Cancer Immunotherapy. Journal of medicinal chemistry 63 (2) (2020)