Ichio Shimada

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 15

Top Topics

Monoclonal Antibody

Structural Basis

Ischemia Reperfusion Injury

Molecular Dynamics Simulations

Top Venues

Science advances

Nature communications

Journal of the American Chemical Society

Nature chemical biology

This page only lists publications with an associated author ORCID identifier.

Publications

Michiko Tajiri, Shunsuke Imai, Tsuyoshi Konuma, Keiko Shimamoto, Ichio Shimada, Satoko Akashi
Evaluation of Drug Responses to Human β 2 AR Using Native Mass Spectrometry. ACS omega 8 (27) (2023)
Yutaro Shiraishi, Ichio Shimada
NMR Characterization of the Papain-like Protease from SARS-CoV-2 Identifies the Conformational Heterogeneity in Its Inhibitor-Binding Site. Journal of the American Chemical Society (2023)
Saeko Yanaka, Yoshiki Yamaguchi, Takeshi Takizawa, Yohei Miyanoiri, Rina Yogo, Ichio Shimada, Koichi Kato
NMR assignments of the N-glycans of the Fc fragment of mouse immunoglobulin G2b glycoprotein. Biomolecular NMR assignments 15 (1) (2021)
Koh Takeuchi, Imai Misaki, Yuji Tokunaga, Miwa Fujisaki, Hajime Kamoshida, Takeshi Takizawa, Hiroyuki Hanzawa, Ichio Shimada
Conformational Plasticity of Cyclic Ras-Inhibitor Peptides Defines Cell Permeabilization Activity. Angewandte Chemie (International ed. in English) 60 (12) (2021)
Shunsuke Imai, Tomoki Yokomizo, Yutaka Kofuku, Yutaro Shiraishi, Takumi Ueda, Ichio Shimada
Structural equilibrium underlying ligand-dependent activation of β2-adrenoreceptor. Nature chemical biology 16 (4) (2020)
Yumiko Mizukoshi, Koh Takeuchi, Yuji Tokunaga, Hitomi Matsuo, Misaki Imai, Miwa Fujisaki, Hajime Kamoshida, Takeshi Takizawa, Hiroyuki Hanzawa, Ichio Shimada
Targeting the cryptic sites: NMR-based strategy to improve protein druggability by controlling the conformational equilibrium. Science advances 6 (40) (2020)
Noritaka Nishida, Yuta Komori, Osamu Takarada, Atsushi Watanabe, Satoko Tamura, Satoshi Kubo, Ichio Shimada, Masahide Kikkawa
Structural basis for two-way communication between dynein and microtubules. Nature communications 11 (1) (2020)
Yuya Terashima, Etsuko Toda, Meiji Itakura, Mikiya Otsuji, Sosuke Yoshinaga, Kazuhiro Okumura, Francis H W Shand, Yoshihiro Komohara, Mitsuhiro Takeda, Kana Kokubo, Ming-Chen Chen, Sana Yokoi, Hirofumi Rokutan, Yutaka Kofuku, Koji Ohnishi, Miki Ohira, Toshihiko Iizasa, Hirofumi Nakano, Takayoshi Okabe, Hirotatsu Kojima, Akira Shimizu, Shiro Kanegasaki, Ming-Rong Zhang, Ichio Shimada, Hiroki Nagase, Hiroaki Terasawa, Kouji Matsushima
Targeting FROUNT with disulfiram suppresses macrophage accumulation and its tumor-promoting properties. Nature communications 11 (1) (2020)
Yuji Tokunaga, Koh Takeuchi, Junya Okude, Kazutomo Ori, Takuya Torizawa, Ichio Shimada
Structural Fingerprints of an Intact Monoclonal Antibody Acquired under Formulated Storage Conditions via 15N Direct Detection Nuclear Magnetic Resonance. Journal of medicinal chemistry 63 (10) (2020)
Yuta Iwahashi, Yuki Toyama, Shunsuke Imai, Hiroaki Itoh, Masanori Osawa, Masayuki Inoue, Ichio Shimada
Conformational equilibrium shift underlies altered K+ channel gating as revealed by NMR. Nature communications 11 (1) (2020)
Takuya Mizumura, Keita Kondo, Masatoshi Kurita, Yutaka Kofuku, Mei Natsume, Shunsuke Imai, Yutaro Shiraishi, Takumi Ueda, Ichio Shimada
Activation of adenosine A2A receptor by lipids from docosahexaenoic acid revealed by NMR. Science advances 6 (12) (2020)
Yuki Toyama, Kenji Kontani, Toshiaki Katada, Ichio Shimada
Decreased conformational stability in the oncogenic N92I mutant of Ras-related C3 botulinum toxin substrate 1. Science advances 5 (8) (2019)
Yuki Toyama, Kenji Kontani, Toshiaki Katada, Ichio Shimada
Conformational landscape alternations promote oncogenic activities of Ras-related C3 botulinum toxin substrate 1 as revealed by NMR. Science advances 5 (3) (2019)
Luhan Zhai, Siyuan Wang, Masayuki Nara, Koh Takeuchi, Ichio Shimada, Yuko Otani, Tomohiko Ohwada
Application of C-Terminal 7-Azabicyclo[2.2.1]heptane to Stabilize β-Strand-like Extended Conformation of a Neighboring α-Amino Acid. The Journal of organic chemistry 83 (21) (2018)
Ayano Mochizuki, Arata Saso, Qingci Zhao, Satoshi Kubo, Noritaka Nishida, Ichio Shimada
Balanced Regulation of Redox Status of Intracellular Thioredoxin Revealed by in-Cell NMR. Journal of the American Chemical Society 140 (10) (2018)