Jakub Tolar (J Tolar)

Scopus Author ID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 38

Top Venues

Blood

The British journal of dermatology

PloS one

Experimental dermatology

University of Minnesota System

University of Minnesota System (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Minnesota System Jul 11 2018

United States

Vice President :: Clinical Affairs

University of Minnesota System Oct 30 2017

United States

Dean :: Medical School

University of Minnesota System Sep 01 2003

United States

Professor :: Pediatrics

University of Minnesota System Jan 01 2013 - Mar 22 2019

United States

Director :: Stem Cell Institute

University of Minnesota System Sep 06 2016 - Oct 30 2017

United States

Executive Vice Dean :: Medical School

Education History

University of Minnesota System Sep 01 1992 - Jun 01 1996

United States

PHD :: Molecular, Cellular & Developmental Biology and Genetics

Publications

Asim Saha, Rahul Palchaudhuri, Leanne Lanieri, Sharon Hyzy, Megan J Riddle, Jamie Panthera, Cindy R Eide, Jakub Tolar, Angela Panoskaltsis-Mortari, Lev Gorfinkel, Victor Tkachev, Ulrike Gerdemann, Francesca Alvarez Calderon, Elisa Rojas Palato, Margaret L MacMillan, John E Wagner, Leslie S Kean, Mark J Osborn, Hans-Peter Kiem, David T Scadden, Lisa M Olson, Bruce R Blazar
Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate-conditioned Fanconi anemia mice. Blood 143 (21) (2024)
Asim Saha, Rahul Palchaudhuri, Leanne Lanieri, Sharon Hyzy, Megan J Riddle, Jamie Panthera, Cindy R Eide, Jakub Tolar, Angela Panoskaltsis-Mortari, Lev Gorfinkel, Victor Tkachev, Ulrike Gerdemann, Francesca Alvarez Calderon, Elisa Rojas Palato, Margaret L MacMillan, John E Wagner, Leslie S Kean, Mark Osborn, Hans-Peter Kiem, David T Scadden, Lisa M Olson, Bruce R Blazar
Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate conditioned Fanconi anemia mice. Blood (2024)
Asim Saha, Rahul Palchaudhuri, Leanne Lanieri, Sharon Hyzy, Megan J Riddle, Jamie Panthera, Cindy R Eide, Jakub Tolar, Angela Panoskaltsis-Mortari, Lev Gorfinkel, Victor Tkachev, Ulrike Gerdemann, Francesca Alvarez Calderon, Elisa Rojas Palato, Margaret L MacMillan, John E Wagner, Leslie S Kean, Mark Osborn, Hans-Peter Kiem, David T Scadden, Lisa M Olson, Bruce R Blazar
Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate conditioned Fanconi anemia mice. Blood (2024)
William Stone, Chloe Strege, William Miller, Aron M Geurts, Michael Grzybowski, Megan J Riddle, Christopher Lees, Cindy R Eide, Douglas R Keene, Sara F Tufa, Davis Seelig, John A McGrath, Jakub Tolar
Creation and characterization of novel rat model for recessive dystrophic epidermolysis bullosa: Frameshift mutation of the Col7a1 gene leads to severe blistered phenotype. PloS one 19 (5) (2024)
Asim Saha, Rahul Palchaudhuri, Leanne Lanieri, Sharon Hyzy, Megan J Riddle, Jamie Panthera, Cindy R Eide, Jakub Tolar, Angela Panoskaltsis-Mortari, Lev Gorfinkel, Victor Tkachev, Ulrike Gerdemann, Francesca Alvarez Calderon, Elisa Rojas Palato, Margaret L MacMillan, John E Wagner, Leslie S Kean, Mark Osborn, Hans-Peter Kiem, David T Scadden, Lisa M Olson, Bruce R Blazar
Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate conditioned Fanconi anemia mice. Blood (2024)
Asim Saha, Rahul Palchaudhuri, Leanne Lanieri, Sharon Hyzy, Megan J Riddle, Jamie Panthera, Cindy R Eide, Jakub Tolar, Angela Panoskaltsis-Mortari, Lev Gorfinkel, Victor Tkachev, Ulrike Gerdemann, Francesca Alvarez Calderon, Elisa Rojas Palato, Margaret L MacMillan, John E Wagner, Leslie S Kean, Mark J Osborn, Hans-Peter Kiem, David T Scadden, Lisa M Olson, Bruce R Blazar
Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate-conditioned Fanconi anemia mice. Blood 143 (21) (2024)
Smriti Pandey, Xin D Gao, Nicholas A Krasnow, Amber McElroy, Y Allen Tao, Jordyn E Duby, Benjamin J Steinbeck, Julia McCreary, Sarah E Pierce, Jakub Tolar, Torsten B Meissner, Elliot L Chaikof, Mark J Osborn, David R Liu
Efficient site-specific integration of large genes in mammalian cells via continuously evolved recombinases and prime editing. Nature biomedical engineering (2024)
William Stone, Chloe Strege, William Miller, Aron M Geurts, Michael Grzybowski, Megan J Riddle, Christopher Lees, Cindy R Eide, Douglas R Keene, Sara F Tufa, Davis Seelig, John A McGrath, Jakub Tolar
Creation and characterization of novel rat model for recessive dystrophic epidermolysis bullosa: Frameshift mutation of the Col7a1 gene leads to severe blistered phenotype. PloS one 19 (5) (2024)
William Stone, Chloe Strege, William Miller, Aron M Geurts, Michael Grzybowski, Megan J Riddle, Christopher Lees, Cindy R Eide, Douglas R Keene, Sara F Tufa, Davis Seelig, John A McGrath, Jakub Tolar
Creation and characterization of novel rat model for recessive dystrophic epidermolysis bullosa: Frameshift mutation of the Col7a1 gene leads to severe blistered phenotype. PloS one 19 (5) (2024)
Asim Saha, Rahul Palchaudhuri, Leanne Lanieri, Sharon Hyzy, Megan J Riddle, Jamie Panthera, Cindy R Eide, Jakub Tolar, Angela Panoskaltsis-Mortari, Lev Gorfinkel, Victor Tkachev, Ulrike Gerdemann, Francesca Alvarez Calderon, Elisa Rojas Palato, Margaret L MacMillan, John E Wagner, Leslie S Kean, Mark Osborn, Hans-Peter Kiem, David T Scadden, Lisa M Olson, Bruce R Blazar
Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate conditioned Fanconi anemia mice. Blood (2024)
Asim Saha, Rahul Palchaudhuri, Leanne Lanieri, Sharon Hyzy, Megan J Riddle, Jamie Panthera, Cindy R Eide, Jakub Tolar, Angela Panoskaltsis-Mortari, Lev Gorfinkel, Victor Tkachev, Ulrike Gerdemann, Francesca Alvarez Calderon, Elisa Rojas Palato, Margaret L MacMillan, John E Wagner, Leslie S Kean, Mark Osborn, Hans-Peter Kiem, David T Scadden, Lisa M Olson, Bruce R Blazar
Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate conditioned Fanconi anemia mice. Blood (2024)
Asim Saha, Rahul Palchaudhuri, Leanne Lanieri, Sharon Hyzy, Megan J Riddle, Jamie Panthera, Cindy R Eide, Jakub Tolar, Angela Panoskaltsis-Mortari, Lev Gorfinkel, Victor Tkachev, Ulrike Gerdemann, Francesca Alvarez Calderon, Elisa Rojas Palato, Margaret L MacMillan, John E Wagner, Leslie S Kean, Mark J Osborn, Hans-Peter Kiem, David T Scadden, Lisa M Olson, Bruce R Blazar
Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate-conditioned Fanconi anemia mice. Blood 143 (21) (2024)
Asim Saha, Rahul Palchaudhuri, Leanne Lanieri, Sharon Hyzy, Megan J Riddle, Jamie Panthera, Cindy R Eide, Jakub Tolar, Angela Panoskaltsis-Mortari, Lev Gorfinkel, Victor Tkachev, Ulrike Gerdemann, Francesca Alvarez Calderon, Elisa Rojas Palato, Margaret L MacMillan, John E Wagner, Leslie S Kean, Mark J Osborn, Hans-Peter Kiem, David T Scadden, Lisa M Olson, Bruce R Blazar
Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate-conditioned Fanconi anemia mice. Blood 143 (21) (2024)
Colby J Feser, James M Williams, Daniel T Lammers, Jason R Bingham, Matthew J Eckert, Jakub Tolar, Mark J Osborn
Engineering Human Cells Expressing CRISPR/Cas9-Synergistic Activation Mediators for Recombinant Protein Production. International journal of molecular sciences 24 (10) (2023)
Teresa Lopes Ramos, Sara Bolivar-Wagers, Sujeong Jin, Govindarajan Thangavelu, Federico Simonetta, Po-Yu Lin, Toshihito Hirai, Asim Saha, Brent H Koehn, Leon L Su, Lora K Picton, Jeanette Baker, Juliane K Lohmeyer, Megan Riddle, Cindy R Eide, Jakub Tolar, Angela Panoskaltsis-Mortari, John E Wagner, K Christopher Garcia, Robert S Negrin, Bruce R Blazar
Prevention of acute GVHD using an orthogonal IL-2/IL-2Rβ system to selectively expand regulatory T cells in vivo. Blood 141 (11) (2023)
Teresa Lopes Ramos, Sara Bolivar-Wagers, Sujeong Jin, Govindarajan Thangavelu, Federico Simonetta, Po-Yu Lin, Toshihito Hirai, Asim Saha, Brent H Koehn, Leon L Su, Lora K Picton, Jeanette Baker, Juliane K Lohmeyer, Megan Riddle, Cindy R Eide, Jakub Tolar, Angela Panoskaltsis-Mortari, John E Wagner, K Christopher Garcia, Robert S Negrin, Bruce R Blazar
Prevention of acute GVHD using an orthogonal IL-2/IL-2Rβ system to selectively expand regulatory T cells in vivo. Blood 141 (11) (2023)
Teresa Lopes Ramos, Sara Bolivar-Wagers, Sujeong Jin, Govindarajan Thangavelu, Federico Simonetta, Po-Yu Lin, Toshihito Hirai, Asim Saha, Brent H Koehn, Leon L Su, Lora K Picton, Jeanette Baker, Juliane K Lohmeyer, Megan J Riddle, Cindy R Eide, Jakub Tolar, Angela Panoskaltsis-Mortari, John E Wagner, K Christopher Garcia, Robert S Negrin, Bruce R Blazar
Prevention of acute GVHD disease using an orthogonal IL-2/IL-2Rβ system to selectively expand regulatory T-cells in vivo. Blood (2022)
Christopher J Sipe, Mitchell G Kluesner, Samuel P Bingea, Walker S Lahr, Aneesha A Andrew, Minjing Wang, Anthony P DeFeo, Timothy L Hinkel, Kanut Laoharawee, John E Wagner, Margaret L MacMillan, Gregory M Vercellotti, Jakub Tolar, Mark J Osborn, R Scott McIvor, Beau R Webber, Branden S Moriarity
Correction of Fanconi Anemia Mutations Using Digital Genome Engineering. International journal of molecular sciences 23 (15) (2022)
William Miller, Charles Lewis Humphrey Pruett, William Stone, Cindy Eide, Megan J Riddle, Courtney Popp, Matthew J Yousefzadeh, Christopher Lees, Davis Seelig, Elizabeth Thompson, Harry Orr, Laura Niedernhofer, Jakub Tolar
Accumulation of senescence observed in spinocerebellar ataxia type 7 mouse model. PloS one 17 (10) (2022)
Elizabeth L Schmidt, Michael Pickett-Leonard, Megan J Riddle, Weili Chen, Frank Wolfgang Albert, Jakub Tolar
Genes and compounds that increase type VII collagen expression as potential treatments for dystrophic epidermolysis bullosa. Experimental dermatology 31 (7) (2022)
Colby J Feser, Christopher J Lees, Daniel T Lammers, Megan J Riddle, Jason R Bingham, Matthew J Eckert, Jakub Tolar, Mark J Osborn
Engineering CRISPR/Cas9 for Multiplexed Recombinant Coagulation Factor Production. International journal of molecular sciences 23 (9) (2022)
Teresa Lopes Ramos, Sara Bolivar-Wagers, Sujeong Jin, Govindarajan Thangavelu, Federico Simonetta, Po-Yu Lin, Toshihito Hirai, Asim Saha, Brent H Koehn, Leon L Su, Lora K Picton, Jeanette Baker, Juliane K Lohmeyer, Megan J Riddle, Cindy R Eide, Jakub Tolar, Angela Panoskaltsis-Mortari, John E Wagner, K Christopher Garcia, Robert S Negrin, Bruce R Blazar
Prevention of acute GVHD disease using an orthogonal IL-2/IL-2Rβ system to selectively expand regulatory T-cells in vivo. Blood (2022)
Teresa Lopes Ramos, Sara Bolivar-Wagers, Sujeong Jin, Govindarajan Thangavelu, Federico Simonetta, Po-Yu Lin, Toshihito Hirai, Asim Saha, Brent H Koehn, Leon L Su, Lora K Picton, Jeanette Baker, Juliane K Lohmeyer, Megan J Riddle, Cindy R Eide, Jakub Tolar, Angela Panoskaltsis-Mortari, John E Wagner, K Christopher Garcia, Robert S Negrin, Bruce R Blazar
Prevention of acute GVHD disease using an orthogonal IL-2/IL-2Rβ system to selectively expand regulatory T-cells in vivo. Blood (2022)
Courtney M Popp, William C Miller, Cindy R Eide, Jakub Tolar
Future applications of 3D bioprinting: A promising technology for treating recessive dystrophic epidermolysis bullosa. Experimental dermatology (2021)
Julia Riedl, Michael Pickett-Leonard, Cindy Eide, Mark Andreas Kluth, Christoph Ganss, Natasha Y Frank, Markus H Frank, Christen L Ebens, Jakub Tolar
ABCB5+ dermal mesenchymal stromal cells with favorable skin homing and local immunomodulation for recessive dystrophic epidermolysis bullosa treatment. Stem cells (Dayton, Ohio) 39 (7) (2021)
Ashley C Kramer, Yuliana Astuti, Alexis Elfstrum, Michael Jonathan Lehrke, Jakub Tolar, Bruce R Blazar, Amanda L Blake, Mandy E Taisto, Justin W Furcich, Erin E Nolan, Wilaiwan Wisessmith Durose, Beau R Webber, Athena Geisness, David K Wood, Troy C Lund
An irradiated marrow niche reveals a small noncollagenous protein mediator of homing, dermatopontin. Blood advances 5 (18) (2021)
Kirk Twaroski, Weili Chen, Michael Pickett-Leonard, Jakub Tolar
Role of transforming growth factor-β1 in recessive dystrophic epidermolysis bullosa squamous cell carcinoma. Experimental dermatology 30 (5) (2021)
Michael Vanden Oever, Daniel M Muldoon, W Mathews, Jakub Tolar
Fludarabine modulates expression of type VII collagen during haematopoietic stem cell transplantation for recessive dystrophic epidermolysis bullosa. The British journal of dermatology 185 (2) (2021)
Mark J Osborn, Akshay Bhardwaj, Samuel P Bingea, Friederike Knipping, Colby J Feser, Christopher J Lees, Daniel P Collins, Clifford J Steer, Bruce R Blazar, Jakub Tolar
CRISPR/Cas9-Based Lateral Flow and Fluorescence Diagnostics. Bioengineering (Basel, Switzerland) 8 (2) (2021)
Christen L Ebens, John A McGrath, J A Riedl, A R Keith, G Lilja, S Rusch, D R Keene, S F Tufa, M J Riddle, R Shanley, A E Van Heest, Jakub Tolar
Immune tolerance of allogeneic haematopoietic cell transplantation supports donor epidermal grafting of recessive dystrophic epidermolysis bullosa chronic wounds. The British journal of dermatology 184 (6) (2020)
Jacob Peter Matson, Raluca Dumitru, Philip Coryell, Ryan M Baxley, Weili Chen, Kirk Twaroski, Beau R Webber, Jakub Tolar, Anja-Katrin Bielinsky, Jeremy E Purvis, Jeanette Gowen Cook
Correction: Rapid DNA replication origin licensing protects stem cell pluripotency. eLife 8 (2019)
K Twaroski, C Eide, M J Riddle, L Xia, C J Lees, W Chen, W Mathews, D R Keene, John A McGrath, Jakub Tolar
Revertant mosaic fibroblasts in recessive dystrophic epidermolysis bullosa. The British journal of dermatology 181 (6) (2019)
C L Ebens, John A McGrath, K Tamai, A Hovnanian, J E Wagner, M J Riddle, D R Keene, T E DeFor, R Tryon, M Chen, D T Woodley, K Hook, Jakub Tolar
Bone marrow transplant with post-transplant cyclophosphamide for recessive dystrophic epidermolysis bullosa expands the related donor pool and permits tolerance of nonhaematopoietic cellular grafts. The British journal of dermatology 181 (6) (2019)
Jangwook P Jung, Wei-Han Lin, Megan J Riddle, Jakub Tolar, Brenda M Ogle
A 3D in vitro model of the dermoepidermal junction amenable to mechanical testing. Journal of biomedical materials research. Part A 106 (12) (2018)
Jing Du, Ryan Flynn, Katelyn Paz, Hong-Gang Ren, Yuko Ogata, Qing Zhang, Philip R Gafken, Barry E Storer, Nathan H Roy, Janis K Burkhardt, Wendy Mathews, Jakub Tolar, Stephanie J Lee, Bruce R Blazar, Sophie Paczesny
Murine chronic graft-versus-host disease proteome profiling discovers CCL15 as a novel biomarker in patients. Blood 131 (15) (2018)
A L Bruckner, D L Fairclough, J A Feinstein, I Lara-Corrales, A W Lucky, Jakub Tolar, Elena Pope
Reliability and validity of the instrument for scoring clinical outcomes of research for epidermolysis bullosa (iscorEB). The British journal of dermatology 178 (5) (2018)
Yan Xing, Michelle J Smith, Christine A Goetz, Ron T McElmurry, Sarah L Parker, Dullei Min, Georg A Hollander, Kenneth I Weinberg, Jakub Tolar, Heather E Stefanski, Bruce R Blazar
Thymic Epithelial Cell Support of Thymopoiesis Does Not Require Klotho. Journal of immunology (Baltimore, Md. : 1950) 201 (11) (2018)
Jacob Peter Matson, Raluca Dumitru, Philip Coryell, Ryan M Baxley, Weili Chen, Kirk Twaroski, Beau R Webber, Jakub Tolar, Anja-Katrin Bielinsky, Jeremy E Purvis, Jeanette Gowen Cook
Rapid DNA replication origin licensing protects stem cell pluripotency. eLife 6 (2017)
Brent H Koehn, Petya Apostolova, Jessica M Haverkamp, Jeffrey S Miller, Valarie McCullar, Jakub Tolar, David H Munn, William J Murphy, Willie June Brickey, Jonathan S Serody, Dmitry I Gabrilovich, Vincenzo Bronte, Peter J Murray, Jenny P-Y Ting, Robert Zeiser, Bruce R Blazar
GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells. Blood 126 (13) (2015)
Jakub Tolar
Sickle cell and silent spleen. Blood 125 (17) (2015)

Jakub Tolar.css-eqlu8i{font-size:small;padding-left:4px;} (J Tolar)

Publication Activity (10 Years)

Top Topics

Top Venues

Jakub Tolar (J Tolar)