Janine Schuurman (J Schuurman)

ORCID

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 24

Top Venues

Journal of immunology (Baltimore, Md. : 1950)

Nature communications

eLife

Proceedings of the National Academy of Sciences of the United States of America

Genmab BV

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Genmab BV

Netherlands

Corporate VP, research & innovation

Publications

Jim Middelburg, Marjolein Sluijter, Gaby Schaap, Büşra Göynük, Katy Lloyd, Vitalijs Ovcinnikovs, Gijs G Zom, Renoud J Marijnissen, Christianne Groeneveldt, Lisa Griffioen, Gerwin G W Sandker, Sandra Heskamp, Sjoerd H van der Burg, Tsolere Arakelian, Ferry Ossendorp, Ramon Arens, Janine Schuurman, Kristel Kemper, Thorbald van Hall
T-cell stimulating vaccines empower CD3 bispecific antibody therapy in solid tumors. Nature communications 15 (1) (2024)
Sjors P A van der Lans, Bart W Bardoel, Maartje Ruyken, Carla J C de Haas, Stan Baijens, Remy M Muts, Lisette M Scheepmaker, Piet C Aerts, Marije F L van 't Wout, Johannes Preiner, Renoud J Marijnissen, Janine Schuurman, Frank J Beurskens, Priscilla F Kerkman, Suzan H M Rooijakkers
Agnostic B cell selection approach identifies antibodies against K. pneumoniae that synergistically drive complement activation. Nature communications 15 (1) (2024)
Jim Middelburg, Marjolein Sluijter, Gaby Schaap, Büşra Göynük, Katy Lloyd, Vitalijs Ovcinnikovs, Gijs G Zom, Renoud J Marijnissen, Christianne Groeneveldt, Lisa Griffioen, Gerwin G W Sandker, Sandra Heskamp, Sjoerd H van der Burg, Tsolere Arakelian, Ferry Ossendorp, Ramon Arens, Janine Schuurman, Kristel Kemper, Thorbald van Hall
T-cell stimulating vaccines empower CD3 bispecific antibody therapy in solid tumors. Nature communications 15 (1) (2024)
Jim Middelburg, Marjolein Sluijter, Gaby Schaap, Büşra Göynük, Katy Lloyd, Vitalijs Ovcinnikovs, Gijs G Zom, Renoud J Marijnissen, Christianne Groeneveldt, Lisa Griffioen, Gerwin G W Sandker, Sandra Heskamp, Sjoerd H van der Burg, Tsolere Arakelian, Ferry Ossendorp, Ramon Arens, Janine Schuurman, Kristel Kemper, Thorbald van Hall
T-cell stimulating vaccines empower CD3 bispecific antibody therapy in solid tumors. Nature communications 15 (1) (2024)
Leire Aguinagalde, Maurits A den Boer, Suzanne M Castenmiller, Seline A Zwarthoff, Carla de Haas, Piet C Aerts, Frank J Beurskens, Janine Schuurman, Albert J R Heck, Kok van Kessel, Suzan H M Rooijakkers
Promoting Fc-Fc interactions between anti-capsular antibodies provides strong immune protection against Streptococcus pneumoniae . eLife 12 (2023)
Timon Damelang, Steven W de Taeye, Rosa Rentenaar, Kasra Roya-Kouchaki, Esther Cw de Boer, Ninotska I L Derksen, Kok van Kessel, Suzanne Lissenberg-Thunnissen, Suzan H M Rooijakkers, Ilse Jongerius, Mirjam M Mebius, Janine Schuurman, Aran F Labrijn, Gestur Vidarsson, Theo Rispens
The Influence of Human IgG Subclass and Allotype on Complement Activation. Journal of immunology (Baltimore, Md. : 1950) (2023)
Leire Aguinagalde, Maurits A den Boer, Suzanne M Castenmiller, Seline A Zwarthoff, Carla de Haas, Piet C Aerts, Frank J Beurskens, Janine Schuurman, Albert J R Heck, Kok van Kessel, Suzan H M Rooijakkers
Promoting Fc-Fc interactions between anti-capsular antibodies provides strong immune protection against Streptococcus pneumoniae . eLife 12 (2023)
Leire Aguinagalde, Maurits A den Boer, Suzanne M Castenmiller, Seline A Zwarthoff, Carla de Haas, Piet C Aerts, Frank J Beurskens, Janine Schuurman, Albert J R Heck, Kok van Kessel, Suzan H M Rooijakkers
Promoting Fc-Fc interactions between anti-capsular antibodies provides strong immune protection against Streptococcus pneumoniae . eLife 12 (2023)
Willemijn van der Wulp, Dennis F G Remst, Michel G D Kester, Renate S Hagedoorn, Paul W H I Parren, Sander I van Kasteren, Janine Schuurman, Wytske M van Weerden, Maaike E Ressing, Boris Bleijlevens, Mirjam H M Heemskerk
Antibody-mediated delivery of viral epitopes to redirect EBV-specific CD8 + T-cell immunity towards cancer cells. Cancer gene therapy (2023)
Simone C Oostindie, Derek A Rinaldi, Gijs G Zom, Michael J Wester, Desiree Paulet, Kusai Al-Tamimi, Els van der Meijden, Jennifer R Scheick, Tessa Wilpshaar, Bart de Jong, Marloes Hoff-van den Broek, Rachel M Grattan, Janita J Oosterhoff, Julie Vignau, Sandra Verploegen, Peter Boross, Frank J Beurskens, Diane S Lidke, Janine Schuurman, Rob N de Jong
Logic-gated antibody pairs that selectively act on cells co-expressing two antigens. Nature biotechnology 40 (10) (2022)
Simone C Oostindie, Greg A Lazar, Janine Schuurman, Paul W H I Parren
Avidity in antibody effector functions and biotherapeutic drug design. Nature reviews. Drug discovery 21 (10) (2022)
Seline A Zwarthoff, Kevin Widmer, Annemarie Kuipers, Juergen Strasser, Maartje Ruyken, Piet C Aerts, Carla J C de Haas, Deniz Ugurlar, Maurits A den Boer, Gestur Vidarsson, Jos A G van Strijp, Piet Gros, Paul W H I Parren, Kok P M van Kessel, Johannes Preiner, Frank J Beurskens, Janine Schuurman, Daniel Ricklin, Suzan H M Rooijakkers
C1q binding to surface-bound IgG is stabilized by C1r2s2 proteases. Proceedings of the National Academy of Sciences of the United States of America 118 (26) (2021)
Ana Rita Cruz, Maurits A den Boer, Juergen Strasser, Seline A Zwarthoff, Frank J Beurskens, Carla J C de Haas, Piet C Aerts, Guanbo Wang, Rob N de Jong, Fabio Bagnoli, Jos A G van Strijp, Kok P M van Kessel, Janine Schuurman, Johannes Preiner, Albert J R Heck, Suzan H M Rooijakkers
Staphylococcal protein A inhibits complement activation by interfering with IgG hexamer formation. Proceedings of the National Academy of Sciences of the United States of America 118 (7) (2021)
Jim Middelburg, Kristel Kemper, Patrick J Engelberts, Aran F Labrijn, Janine Schuurman, Thorbald van Hall
Overcoming Challenges for CD3-Bispecific Antibody Therapy in Solid Tumors. Cancers 13 (2) (2021)
Marije B Overdijk, Kristin Strumane, Frank J Beurskens, Antonio Ortiz Buijsse, Claudine Vermot-Desroches, Boris S Vuillermoz, Thessa Kroes, Rob N de Jong, Naomi Hoevenaars, Richard G Hibbert, Andreas Lingnau, Ulf Forssmann, Janine Schuurman, Paul W H I Parren, Esther C W Breij
Dual Epitope Targeting and Enhanced Hexamerization by DR5 Antibodies as a Novel Approach to Induce Potent Antitumor Activity Through DR5 Agonism. Molecular cancer therapeutics 19 (10) (2020)
Sunita Gulati, Frank J Beurskens, Bart-Jan de Kreuk, Marcel Roza, Bo Zheng, Rosane B DeOliveira, Jutamas Shaughnessy, Nancy A Nowak, Ronald P Taylor, Marina Botto, Xianbao He, Robin R Ingalls, Trent M Woodruff, Wen-Chao Song, Janine Schuurman, Peter A Rice, Sanjay Ram
Complement alone drives efficacy of a chimeric antigonococcal monoclonal antibody. PLoS biology 17 (6) (2019)
Patrick J Engelberts, Esther C W Breij, Thomas Valerius, Janine Schuurman, Paul W H I Parren, Frank J Beurskens
Response to Comment on "Type I CD20 Antibodies Recruit the B Cell Receptor for Complement-Dependent Lysis of Malignant B Cells". Journal of immunology (Baltimore, Md. : 1950) 200 (8) (2019)
Deniz Ugurlar, Stuart C Howes, Bart-Jan de Kreuk, Roman I Koning, Rob N de Jong, Frank J Beurskens, Janine Schuurman, Abraham J Koster, Thomas H Sharp, Paul W H I Parren, Piet Gros
Structures of C1-IgG1 provide insights into how danger pattern recognition activates complement. Science (New York, N.Y.) 359 (6377) (2018)
Hreinn Benonisson, Işıl Altıntaş, Marjolein Sluijter, Sandra Verploegen, Aran F Labrijn, Danita H Schuurhuis, Mischa A Houtkamp, J Sjef Verbeek, Janine Schuurman, Thorbald van Hall
CD3-Bispecific Antibody Therapy Turns Solid Tumors into Inflammatory Sites but Does Not Install Protective Memory. Molecular cancer therapeutics 18 (2) (2018)
Annalina Tammen, Stefanie Derer, Ralf Schwanbeck, Thies Rösner, Anna Kretschmer, Frank J Beurskens, Janine Schuurman, Paul W H I Parren, Thomas Valerius
Monoclonal Antibodies against Epidermal Growth Factor Receptor Acquire an Ability To Kill Tumor Cells through Complement Activation by Mutations That Selectively Facilitate the Hexamerization of IgG on Opsonized Cells. Journal of immunology (Baltimore, Md. : 1950) 198 (4) (2017)
Mario Losen, Aran F Labrijn, Vivianne H van Kranen-Mastenbroek, Maarten L Janmaat, Krista G Haanstra, Frank J Beurskens, Tom Vink, Margreet Jonker, Bert A 't Hart, Marina Mané-Damas, Peter C Molenaar, Pilar Martinez-Martinez, Eline van der Esch, Janine Schuurman, Marc H de Baets, Paul W H I Parren
Hinge-deleted IgG4 blocker therapy for acetylcholine receptor myasthenia gravis in rhesus monkeys. Scientific reports 7 (1) (2017)
Aran F Labrijn, Joyce I Meesters, Matthew Bunce, Anthony A Armstrong, Sandeep Somani, Tom C Nesspor, Mark L Chiu, Işil Altintaş, Sandra Verploegen, Janine Schuurman, Paul W H I Parren
Efficient Generation of Bispecific Murine Antibodies for Pre-Clinical Investigations in Syngeneic Rodent Models. Scientific reports 7 (1) (2017)
Patrick J Engelberts, Marleen Voorhorst, Janine Schuurman, Tom van Meerten, Joost M Bakker, Tom Vink, Wendy J M Mackus, Esther C W Breij, Stefanie Derer, Thomas Valerius, Jan G J van de Winkel, Paul W H I Parren, Frank J Beurskens
Type I CD20 Antibodies Recruit the B Cell Receptor for Complement-Dependent Lysis of Malignant B Cells. Journal of immunology (Baltimore, Md. : 1950) 197 (12) (2016)
Erika M Cook, Margaret A Lindorfer, Hilma van der Horst, Simone Oostindie, Frank J Beurskens, Janine Schuurman, Clive S Zent, Richard Burack, Paul W H I Parren, Ronald P Taylor
Antibodies That Efficiently Form Hexamers upon Antigen Binding Can Induce Complement-Dependent Cytotoxicity under Complement-Limiting Conditions. Journal of immunology (Baltimore, Md. : 1950) 197 (5) (2016)
Aran F Labrijn, Joyce I Meesters, Patrick Priem, Rob N de Jong, Ewald T J van den Bremer, Muriel D van Kampen, Arnout F Gerritsen, Janine Schuurman, Paul W H I Parren
Controlled Fab-arm exchange for the generation of stable bispecific IgG1. Nature protocols 9 (10) (2014)

Janine Schuurman.css-eqlu8i{font-size:small;padding-left:4px;} (J Schuurman)

Publication Activity (10 Years)

Top Topics

Top Venues

Janine Schuurman (J Schuurman)