Jean-Louis Reymond

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 81

Top Venues

Journal of chemical information and modeling

Chemical science

ACS synthetic biology

Chimia

Universität Bern

Université de Lausanne (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Universität Bern

Switzerland

Professor :: Departement für Chemie und Biochemie

Scripps Research Institute

United States

Assistant Professor :: Molecular Biology

Scripps Research Institute

United States

Post-doc :: Molecular Biology

Education History

Université de Lausanne

Switzerland

PHD :: Chimie

Publications

Andrea Marco Amati, Stefan Urs Moning, Sacha Javor, Sandra Schär, Sabina Deutschmann, Jean-Louis Reymond, Christoph von Ballmoos
Overcoming Protein Orientation Mismatch Enables Efficient Nanoscale Light-Driven ATP Production. ACS synthetic biology 13 (4) (2024)
Andrea Marco Amati, Stefan Urs Moning, Sacha Javor, Sandra Schär, Sabina Deutschmann, Jean-Louis Reymond, Christoph von Ballmoos
Overcoming Protein Orientation Mismatch Enables Efficient Nanoscale Light-Driven ATP Production. ACS synthetic biology 13 (4) (2024)
Andrea Marco Amati, Stefan Urs Moning, Sacha Javor, Sandra Schär, Sabina Deutschmann, Jean-Louis Reymond, Christoph von Ballmoos
Overcoming Protein Orientation Mismatch Enables Efficient Nanoscale Light-Driven ATP Production. ACS synthetic biology 13 (4) (2024)
Andrea Marco Amati, Stefan Urs Moning, Sacha Javor, Sandra Schär, Sabina Deutschmann, Jean-Louis Reymond, Christoph von Ballmoos
Overcoming Protein Orientation Mismatch Enables Efficient Nanoscale Light-Driven ATP Production. ACS synthetic biology (2024)
Olivier Jordan, Bee-Ha Gan, Sari Alwan, Karl Perron, Emmanuelle Sublet, Verena Ducret, Hua Ye, Gerrit Borchard, Jean-Louis Reymond, Viorica Patrulea
Highly Potent Cationic Chitosan Derivatives Coupled to Antimicrobial Peptide Dendrimers to Combat Pseudomonas aeruginosa. Advanced healthcare materials 13 (19) (2024)
Olivier Jordan, Bee-Ha Gan, Sari Alwan, Karl Perron, Emmanuelle Sublet, Verena Ducret, Hua Ye, Gerrit Borchard, Jean-Louis Reymond, Viorica Patrulea
Highly Potent Cationic Chitosan Derivatives Coupled to Antimicrobial Peptide Dendrimers to Combat Pseudomonas aeruginosa. Advanced healthcare materials (2024)
Andrea Marco Amati, Stefan Urs Moning, Sacha Javor, Sandra Schär, Sabina Deutschmann, Jean-Louis Reymond, Christoph von Ballmoos
Overcoming Protein Orientation Mismatch Enables Efficient Nanoscale Light-Driven ATP Production. ACS synthetic biology 13 (4) (2024)
Markus Orsi, Jean-Louis Reymond
Can large language models predict antimicrobial peptide activity and toxicity? RSC medicinal chemistry 15 (6) (2024)
Olivier Jordan, Bee-Ha Gan, Sari Alwan, Karl Perron, Emmanuelle Sublet, Verena Ducret, Hua Ye, Gerrit Borchard, Jean-Louis Reymond, Viorica Patrulea
Highly Potent Cationic Chitosan Derivatives Coupled to Antimicrobial Peptide Dendrimers to Combat Pseudomonas Aeruginosa. Advanced healthcare materials (2024)
Andrea Marco Amati, Stefan Urs Moning, Sacha Javor, Sandra Schär, Sabina Deutschmann, Jean-Louis Reymond, Christoph von Ballmoos
Overcoming Protein Orientation Mismatch Enables Efficient Nanoscale Light-Driven ATP Production. ACS synthetic biology 13 (4) (2024)
Susanna Zamolo, Elena Zakharova, Lise Boursinhac, Florian Hollfelder, Tamis Darbre, Jean-Louis Reymond
Peptide dendrimers transfecting CRISPR/Cas9 plasmid DNA: optimization and mechanism. RSC chemical biology 5 (9) (2024)
Markus Orsi, Jean-Louis Reymond
Can large language models predict antimicrobial peptide activity and toxicity? RSC medicinal chemistry 15 (6) (2024)
Markus Orsi, Daniel Probst, Philippe Schwaller, Jean-Louis Reymond
Alchemical analysis of FDA approved drugs. Digital discovery 2 (5) (2023)
Hippolyte Personne, Thissa N Siriwardena, Sacha Javor, Jean-Louis Reymond
Dipropylamine for 9-Fluorenylmethyloxycarbonyl (Fmoc) Deprotection with Reduced Aspartimide Formation in Solid-Phase Peptide Synthesis. ACS omega 8 (5) (2023)
Joël S Bloch, Alan John, Runyu Mao, Somnath Mukherjee, Jérémy Boilevin, Rossitza N Irobalieva, Tamis Darbre, Nichollas E Scott, Jean-Louis Reymond, Anthony A Kossiakoff, Ethan D Goddard-Borger, Kaspar P Locher
Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase. Nature chemical biology (2023)
Hippolyte Personne, Thierry Paschoud, Sofia Fulgencio, Stéphane Baeriswyl, Thilo Köhler, Christian van Delden, Achim Stocker, Sacha Javor, Jean-Louis Reymond
To Fold or Not to Fold: Diastereomeric Optimization of an α-Helical Antimicrobial Peptide. Journal of medicinal chemistry (2023)
David Kreutter, Jean-Louis Reymond
Multistep retrosynthesis combining a disconnection aware triple transformer loop with a route penalty score guided tree search. Chemical science 14 (36) (2023)
Etienne Bonvin, Hippolyte Personne, Thierry Paschoud, Jérémie Reusser, Bee-Ha Gan, Alexandre Luscher, Thilo Köhler, Christian van Delden, Jean-Louis Reymond
Antimicrobial Peptide-Peptoid Hybrids with and without Membrane Disruption. ACS infectious diseases 9 (12) (2023)
Joël S Bloch, Alan John, Runyu Mao, Somnath Mukherjee, Jérémy Boilevin, Rossitza N Irobalieva, Tamis Darbre, Nichollas E Scott, Jean-Louis Reymond, Anthony A Kossiakoff, Ethan D Goddard-Borger, Kaspar P Locher
Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase. Nature chemical biology (2023)
Hippolyte Personne, Thissa N Siriwardena, Sacha Javor, Jean-Louis Reymond
Dipropylamine for 9-Fluorenylmethyloxycarbonyl (Fmoc) Deprotection with Reduced Aspartimide Formation in Solid-Phase Peptide Synthesis. ACS omega 8 (5) (2023)
Ye Buehler, Jean-Louis Reymond
Expanding Bioactive Fragment Space with the Generated Database GDB-13s. Journal of chemical information and modeling (2023)
Valentina Rossetti, Jean-Louis Reymond
Vitaport: A Learning and Artistic Path for Public Outreach on Transporter Biology, Health and Drug Discovery. Chimia 76 (12) (2022)
Johannes Morstein, Alice Capecchi, Konstantin Hinnah, ByungUk Park, Jerome Petit-Jacques, Reid C Van Lehn, Jean-Louis Reymond, Dirk H Trauner
Medium-Chain Lipid Conjugation Facilitates Cell-Permeability and Bioactivity. Journal of the American Chemical Society 144 (40) (2022)
Manh Tin Ho, Stephan Berger, Philipp Müller, Céline Simonin, Jean-Louis Reymond, Christoph Von Ballmoos, Daniel G Fuster
Physiological and Molecular Function of the Sodium/Hydrogen Exchanger NHA2 (SLC9B2). Chimia 76 (12) (2022)
Ye Buehler, Jean-Louis Reymond
Molecular Framework Analysis of the Generated Database GDB-13s. Journal of chemical information and modeling 63 (2) (2022)
Ye Buehler, Jean-Louis Reymond
Molecular Framework Analysis of the Generated Database GDB-13s. Journal of chemical information and modeling (2022)
Ye Buehler, Jean-Louis Reymond
Molecular Framework Analysis of the Generated Database GDB-13s. Journal of chemical information and modeling 63 (2) (2022)
Jean-Louis Reymond
Molecular Similarity for Drug Discovery, Target Prediction and Chemical Space Visualization. Chimia 76 (12) (2022)
Elena Zakharova, Markus Orsi, Alice Capecchi, Jean-Louis Reymond
Machine Learning Guided Discovery of Non-Hemolytic Membrane Disruptive Anticancer Peptides. ChemMedChem 17 (17) (2022)
Ye Buehler, Jean-Louis Reymond
Molecular Framework Analysis of the Generated Database GDB-13s. Journal of chemical information and modeling 63 (2) (2022)
Ye Buehler, Jean-Louis Reymond
Molecular Framework Analysis of the Generated Database GDB-13s. Journal of chemical information and modeling 63 (2) (2022)
Daniel Probst, Philippe Schwaller, Jean-Louis Reymond
Reaction classification and yield prediction using the differential reaction fingerprint DRFP. Digital discovery 1 (2) (2022)
Hugues Abriel, Jean-Louis Reymond
NCCR TransCure - Excellence in Membrane Transport Research from 2010 until 2022. Chimia 76 (12) (2022)
Dina Erzina, Alice Capecchi, Sacha Javor, Jean-Louis Reymond
An Immunomodulatory Peptide Dendrimer Inspired from Glatiramer Acetate. Angewandte Chemie (International ed. in English) 60 (50) (2021)
Stéphane Baeriswyl, Hippolyte Personne, Ivan Di Bonaventura, Thilo Köhler, Christian van Delden, Achim Stocker, Sacha Javor, Jean-Louis Reymond
A mixed chirality α-helix in a stapled bicyclic and a linear antimicrobial peptide revealed by X-ray crystallography. RSC chemical biology 2 (6) (2021)
Amol Thakkar, Veronika Chadimová, Esben Jannik Bjerrum, Ola Engkvist, Jean-Louis Reymond
Retrosynthetic accessibility score (RAscore) - rapid machine learned synthesizability classification from AI driven retrosynthetic planning. Chemical science 12 (9) (2021)
Alice Capecchi, Jean-Louis Reymond
Classifying natural products from plants, fungi or bacteria using the COCONUT database and machine learning. Journal of cheminformatics 13 (1) (2021)
David Kreutter, Philippe Schwaller, Jean-Louis Reymond
Predicting enzymatic reactions with a molecular transformer. Chemical science 12 (25) (2021)
Haneen Daralnakhla, Osama Saher, Susanna Zamolo, Tõnis Lehto, Jeremy P Bost, Marc Heitz, Karin E Lundin, Samir El Andaloussi, Tamis Darbre, Jean-Louis Reymond, Rula Zain, Carl Inge Edvard Smith
Lipophilic Peptide Dendrimers for Delivery of Splice-Switching Oligonucleotides. Pharmaceutics 13 (1) (2021)
Xingguang Cai, Sacha Javor, Bee Ha Gan, Thilo Köhler, Jean-Louis Reymond
The antibacterial activity of peptide dendrimers and polymyxin B increases sharply above pH 7.4. Chemical communications (Cambridge, England) 57 (46) (2021)
Philippe Schwaller, Benjamin Hoover, Jean-Louis Reymond, Hendrik Strobelt, Teodoro Laino
Extraction of organic chemistry grammar from unsupervised learning of chemical reactions. Science advances 7 (15) (2021)
Alice Capecchi, Xingguang Cai, Hippolyte Personne, Thilo Köhler, Christian van Delden, Jean-Louis Reymond
Machine learning designs non-hemolytic antimicrobial peptides. Chemical science 12 (26) (2021)
Paris Jafari, Alexandre Luscher, Thissa Siriwardena, Murielle Michetti, Yok-Ai Que, Laurence G Rahme, Jean-Louis Reymond, Wassim Raffoul, Christian Van Delden, Lee Ann Applegate, Thilo Köhler
Antimicrobial Peptide Dendrimers and Quorum-Sensing Inhibitors in Formulating Next-Generation Anti-Infection Cell Therapy Dressings for Burns. Molecules (Basel, Switzerland) 26 (13) (2021)
Alice Capecchi, Jean-Louis Reymond
Assigning the Origin of Microbial Natural Products by Chemical Space Map and Machine Learning. Biomolecules 10 (10) (2020)
Marion Poirier, Jonai Pujol-Giménez, Cristina Manatschal, Sven Bühlmann, Ahmed Embaby, Sacha Javor, Matthias A Hediger, Jean-Louis Reymond
Pyrazolyl-pyrimidones inhibit the function of human solute carrier protein SLC11A2 (hDMT1) by metal chelation. RSC medicinal chemistry 11 (9) (2020)
Marc Heitz, Susanna Zamolo, Sacha Javor, Jean-Louis Reymond
Fluorescent Peptide Dendrimers for siRNA Transfection: Tracking pH Responsive Aggregation, siRNA Binding, and Cell Penetration. Bioconjugate chemistry 31 (6) (2020)
Alice Capecchi, Daniel Probst, Jean-Louis Reymond
One molecular fingerprint to rule them all: drugs, biomolecules, and the metabolome. Journal of cheminformatics 12 (1) (2020)
Bee-Ha Gan, Xingguang Cai, Sacha Javor, Thilo Köhler, Jean-Louis Reymond
Synergistic Effect of Propidium Iodide and Small Molecule Antibiotics with the Antimicrobial Peptide Dendrimer G3KL against Gram-Negative Bacteria. Molecules (Basel, Switzerland) 25 (23) (2020)
Giorgio Pesciullesi, Philippe Schwaller, Teodoro Laino, Jean-Louis Reymond
Transfer learning enables the molecular transformer to predict regio- and stereoselective reactions on carbohydrates. Nature communications 11 (1) (2020)
Amol Thakkar, Nidhal Selmi, Jean-Louis Reymond, Ola Engkvist, Esben Jannik Bjerrum
"Ring Breaker": Neural Network Driven Synthesis Prediction of the Ring System Chemical Space. Journal of medicinal chemistry 63 (16) (2020)
Daniel Probst, Jean-Louis Reymond
Visualization of very large high-dimensional data sets as minimum spanning trees. Journal of cheminformatics 12 (1) (2020)
Kris Meier, Josep Arús-Pous, Jean-Louis Reymond
A Potent and Selective Janus Kinase Inhibitor with a Chiral 3D-Shaped Triquinazine Ring System from Chemical Space. Angewandte Chemie (International ed. in English) 60 (4) (2020)
Micael Rodrigues Cunha, Rajesh Bhardwaj, Aline Lucie Carrel, Sonja Lindinger, Christoph Romanin, Roberto Parise-Filho, Matthias A Hediger, Jean-Louis Reymond
Natural product inspired optimization of a selective TRPV6 calcium channel inhibitor. RSC medicinal chemistry 11 (9) (2020)
Martin Fitzner, Georg Wuitschik, Raffael J Koller, Jean-Michel Adam, Torsten Schindler, Jean-Louis Reymond
What can reaction databases teach us about Buchwald-Hartwig cross-couplings? Chemical science 11 (48) (2020)
Alice Capecchi, Alain Zhang, Jean-Louis Reymond
Populating Chemical Space with Peptides Using a Genetic Algorithm. Journal of chemical information and modeling 60 (1) (2020)
Rajesh Bhardwaj, Sonja Lindinger, Arthur Neuberger, Kirill D Nadezhdin, Appu K Singh, Micael Rodrigues Cunha, Isabella Derler, Gergely Gyimesi, Jean-Louis Reymond, Matthias A Hediger, Christoph Romanin, Alexander I Sobolevsky
Inactivation-mimicking block of the epithelial calcium channel TRPV6. Science advances 6 (48) (2020)
Mahendra Awale, Finton Sirockin, Nikolaus Stiefl, Jean-Louis Reymond
Drug Analogs from Fragment-Based Long Short-Term Memory Generative Neural Networks. Journal of chemical information and modeling 59 (4) (2019)
Bee-Ha Gan, Thissa N Siriwardena, Sacha Javor, Tamis Darbre, Jean-Louis Reymond
Fluorescence Imaging of Bacterial Killing by Antimicrobial Peptide Dendrimer G3KL. ACS infectious diseases 5 (12) (2019)
Stéphane Baeriswyl, Bee-Ha Gan, Thissa N Siriwardena, Ricardo Visini, Maurane Robadey, Sacha Javor, Achim Stocker, Tamis Darbre, Jean-Louis Reymond
X-ray Crystal Structures of Short Antimicrobial Peptides as Pseudomonas aeruginosa Lectin B Complexes. ACS chemical biology 14 (4) (2019)
Mahendra Awale, Finton Sirockin, Nikolaus Stiefl, Jean-Louis Reymond
Medicinal Chemistry Aware Database GDBMedChem. Molecular informatics 38 (8-9) (2019)
Cristina Manatschal, Jonai Pujol-Giménez, Marion Poirier, Jean-Louis Reymond, Matthias A Hediger, Raimund Dutzler
Mechanistic basis of the inhibition of SLC11/NRAMP-mediated metal ion transport by bis-isothiourea substituted compounds. eLife 8 (2019)
Alice Capecchi, Mahendra Awale, Daniel Probst, Jean-Louis Reymond
PubChem and ChEMBL beyond Lipinski. Molecular informatics 38 (5) (2019)
Marc Heitz, Sacha Javor, Tamis Darbre, Jean-Louis Reymond
Stereoselective pH Responsive Peptide Dendrimers for siRNA Transfection. Bioconjugate chemistry 30 (8) (2019)
Marwa Taouai, Khouloud Chakroun, Roman Sommer, Gaelle Michaud, David Giacalone, Mohamed Amine Ben Maaouia, Aurélie Vallin-Butruille, David Mathiron, Rym Abidi, Tamis Darbre, Peter J Cragg, Catherine Mullié, Jean-Louis Reymond, George A O'Toole, Mohammed Benazza
Glycocluster Tetrahydroxamic Acids Exhibiting Unprecedented Inhibition of Pseudomonas aeruginosa Biofilms. Journal of medicinal chemistry 62 (17) (2019)
Amol Thakkar, Thierry Kogej, Jean-Louis Reymond, Ola Engkvist, Esben Jannik Bjerrum
Datasets and their influence on the development of computer assisted synthesis planning tools in the pharmaceutical domain. Chemical science 11 (1) (2019)
Daniel Probst, Jean-Louis Reymond
Exploring DrugBank in Virtual Reality Chemical Space. Journal of chemical information and modeling 58 (9) (2018)
Maja Napiórkowska, Jérémy Boilevin, Tamis Darbre, Jean-Louis Reymond, Kaspar P Locher
Structure of bacterial oligosaccharyltransferase PglB bound to a reactive LLO and an inhibitory peptide. Scientific reports 8 (1) (2018)
Daniel Probst, Jean-Louis Reymond
SmilesDrawer: Parsing and Drawing SMILES-Encoded Molecular Structures Using Client-Side JavaScript. Journal of chemical information and modeling 58 (1) (2018)
Ana S Ramírez, Jérémy Boilevin, Ahmad Reza Mehdipour, Gerhard Hummer, Tamis Darbre, Jean-Louis Reymond, Kaspar P Locher
Structural basis of the molecular ruler mechanism of a bacterial glycosyltransferase. Nature communications 9 (1) (2018)
Mahendra Awale, Jean-Louis Reymond
Polypharmacology Browser PPB2: Target Prediction Combining Nearest Neighbors with Machine Learning. Journal of chemical information and modeling 59 (1) (2018)
Thissa N Siriwardena, Alice Capecchi, Bee-Ha Gan, Xian Jin, Runze He, Dengwen Wei, Lan Ma, Thilo Köhler, Christian van Delden, Sacha Javor, Jean-Louis Reymond
Optimizing Antimicrobial Peptide Dendrimers in Chemical Space. Angewandte Chemie (International ed. in English) 57 (28) (2018)
Marion Poirier, Mahendra Awale, Matthias A Roelli, Guy T Giuffredi, Lars Ruddigkeit, Lasse Evensen, Amandine Stooss, Serafina Calarco, James B Lorens, Roch-Philippe Charles, Jean-Louis Reymond
Identifying Lysophosphatidic Acid Acyltransferase β (LPAAT-β) as the Target of a Nanomolar Angiogenesis Inhibitor from a Phenotypic Screen Using the Polypharmacology Browser PPB2. ChemMedChem 14 (2) (2018)
Ricardo Visini, Mahendra Awale, Jean-Louis Reymond
Fragment Database FDB-17. Journal of chemical information and modeling 57 (4) (2017)
Víctor Sebastián-Pérez, Carlos Roca, Mahendra Awale, Jean-Louis Reymond, Ana Martinez, Carmen Gil, Nuria Eugenia Campillo
Medicinal and Biological Chemistry (MBC) Library: An Efficient Source of New Hits. Journal of chemical information and modeling 57 (9) (2017)
Ricardo Visini, Josep Arús-Pous, Mahendra Awale, Jean-Louis Reymond
Virtual Exploration of the Ring Systems Chemical Universe. Journal of chemical information and modeling 57 (11) (2017)
Ivan Di Bonaventura, Xian Jin, Ricardo Visini, Daniel Probst, Sacha Javor, Bee-Ha Gan, Gaëlle Michaud, Antonino Natalello, Silvia Maria Doglia, Thilo Köhler, Christian van Delden, Achim Stocker, Tamis Darbre, Jean-Louis Reymond
Chemical space guided discovery of antimicrobial bridged bicyclic peptides against Pseudomonas aeruginosa and its biofilms. Chemical science 8 (10) (2017)
Maja Napiórkowska, Jérémy Boilevin, Tina Sovdat, Tamis Darbre, Jean-Louis Reymond, Markus Aebi, Kaspar P Locher
Molecular basis of lipid-linked oligosaccharide recognition and processing by bacterial oligosaccharyltransferase. Nature structural & molecular biology 24 (12) (2017)
Thissa N Siriwardena, Michaela Stach, Runze He, Bee-Ha Gan, Sacha Javor, Marc Heitz, Lan Ma, Xiangju Cai, Peng Chen, Dengwen Wei, Hongtao Li, Jun Ma, Thilo Köhler, Christian van Delden, Tamis Darbre, Jean-Louis Reymond
Lipidated Peptide Dendrimers Killing Multidrug-Resistant Bacteria. Journal of the American Chemical Society 140 (1) (2017)
Daniel Probst, Marc Heitz, Marion Poirier, Bee Ha Gan, Clémence Delalande, Jean-Louis Reymond
Frontiers in Medicinal Chemistry 2017 in Bern, Switzerland. ChemMedChem 12 (19) (2017)
Mahendra Awale, Daniel Probst, Jean-Louis Reymond
WebMolCS: A Web-Based Interface for Visualizing Molecules in Three-Dimensional Chemical Spaces. Journal of chemical information and modeling 57 (4) (2017)
Runze He, Ivan Di Bonaventura, Ricardo Visini, Bee-Ha Gan, Yongchun Fu, Daniel Probst, Alexandre Lüscher, Thilo Köhler, Christian van Delden, Achim Stocker, Wenjing Hong, Tamis Darbre, Jean-Louis Reymond
Design, crystal structure and atomic force microscopy study of thioether ligated d,l-cyclic antimicrobial peptides against multidrug resistant Pseudomonas aeruginosa. Chemical science 8 (11) (2017)
Marco Bartoloni, Xian Jin, Maria José Marcaida, João Banha, Ivan Dibonaventura, Swathi Bongoni, Kathrin Bartho, Olivia Gräbner, Michael Sefkow, Tamis Darbre, Jean-Louis Reymond
Bridged bicyclic peptides as potential drug scaffolds: synthesis, structure, protein binding and stability. Chemical science 6 (10) (2015)

Jean-Louis Reymond.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Jean-Louis Reymond