John K Eaton

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 9

Top Topics

Iron Deficiency

Pluripotent Stem Cells

Crystal Structure

Top Venues

Nature chemical biology

bioRxiv : the preprint server for biology

Acta crystallographica. Section D, Structural biology

This page only lists publications with an associated author ORCID identifier.

Publications

Priya Chatterji, Gang Xing, Laura Furst, Krishna Dave, Qiong Zhou, Daniel V LaBarbera, Douglas H Thamm, John K Eaton, Mathias J Wawer, Vasanthi S Viswanathan
Validation of ferroptosis in canine cancer cells to enable comparative oncology and translational medicine. bioRxiv : the preprint server for biology (2024)
Priya Chatterji, Gang Xing, Laura Furst, Krishna Dave, Qiong Zhou, Daniel V LaBarbera, Douglas H Thamm, John K Eaton, Mathias J Wawer, Vasanthi S Viswanathan
Validation of ferroptosis in canine cancer cells to enable comparative oncology and translational medicine. bioRxiv : the preprint server for biology (2024)
Peter Tsvetkov, Shannon Coy, Boryana Petrova, Margaret Dreishpoon, Ana Verma, Mai Abdusamad, Jordan Rossen, Lena M Joesch-Cohen, Ranad Humeidi, Ryan D Spangler, John K Eaton, Evgeni Frenkel, Mustafa Kocak, Steven M Corsello, Svetlana Lutsenko, Naama Kanarek, Sandro Santagata, Todd R Golub
Copper induces cell death by targeting lipoylated TCA cycle proteins. Science (New York, N.Y.) 375 (6586) (2022)
Dieter Moosmayer, André Hilpmann, Jutta Hoffmann, Lennart Schnirch, Katja Zimmermann, Volker Badock, Laura Furst, John K Eaton, Vasanthi S Viswanathan, Stuart L Schreiber, Stefan Gradl, Roman Christian Hillig
Crystal structures of the selenoprotein glutathione peroxidase 4 in its apo form and in complex with the covalently bound inhibitor ML162. Acta crystallographica. Section D, Structural biology 77 (Pt 2) (2021)
Yilong Zou, Whitney S Henry, Emily L Ricq, Emily T Graham, Vaishnavi V Phadnis, Pema Maretich, Sateja Paradkar, Natalie Boehnke, Amy A Deik, Ferenc Reinhardt, John K Eaton, Bryan Ferguson, Wenyu Wang, Joshua Fairman, Heather R Keys, Vlado Dančík, Andrew T Chan, Paul A Clemons, Paula T Hammond, Laurie A Boyer, Robert A Weinberg, Stuart L Schreiber
Plasticity of ether lipids promotes ferroptosis susceptibility and evasion. Nature 585 (7826) (2020)
Yilong Zou, Haoxin Li, Emily T Graham, Amy A Deik, John K Eaton, Wenyu Wang, Gerardo Sandoval-Gomez, Andrew T Chan, John G Doench, Stuart L Schreiber
Cytochrome P450 oxidoreductase contributes to phospholipid peroxidation in ferroptosis. Nature chemical biology 16 (3) (2020)
John K Eaton, Laura Furst, Richard A Ruberto, Dieter Moosmayer, André Hilpmann, Matthew J Ryan, Katja Zimmermann, Luke L Cai, Michael Niehues, Volker Badock, Anneke Kramm, Sixun Chen, Roman C Hillig, Paul A Clemons, Stefan Gradl, Claire Montagnon, Kiel E Lazarski, Sven Christian, Besnik Bajrami, Roland Neuhaus, Ashley L Eheim, Vasanthi S Viswanathan, Stuart L Schreiber
Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles. Nature chemical biology 16 (5) (2020)
Yilong Zou, Michael J Palte, Amy A Deik, Haoxin Li, John K Eaton, Wenyu Wang, Yuen-Yi Tseng, Rebecca Deasy, Maria Kost-Alimova, Vlado Dančík, Elizaveta S Leshchiner, Vasanthi S Viswanathan, Sabina Signoretti, Toni K Choueiri, Jesse S Boehm, Bridget K Wagner, John G Doench, Andrew T Chan, Paul A Clemons, Stuart L Schreiber
A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis. Nature communications 10 (1) (2019)
John K Eaton, Richard A Ruberto, Anneke Kramm, Vasanthi S Viswanathan, Stuart L Schreiber
Diacylfuroxans Are Masked Nitrile Oxides That Inhibit GPX4 Covalently. Journal of the American Chemical Society 141 (51) (2019)