Jon S Thorson

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 32

Top Venues

Journal of natural products

ACS synthetic biology

ACS chemical biology

Acta crystallographica. Section F, Structural biology communications

University of Kentucky

University of Minnesota System (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Kentucky Oct 31 2011

United States

Professor :: Pharmacy

University of Wisconsin Madison

United States

Professor :: Pharmacy

Weill Cornell Medical College

United States

Professor :: Pharmacology

Memorial Sloan-Kettering Cancer Center

United States

Professor/Member :: Molecular Therapeutics

Education History

University of Minnesota System

United States

PHD :: Chemistry

Publications

Rongbin Wang, Benjamin Nji Wandi, Nora Schwartz, Jacob Hecht, Larissa Ponomareva, Kendall Paige, Alexis West, Kathryn Desanti, Jennifer Nguyen, Jarmo Niemi, Jon S Thorson, Khaled A Shaaban, Mikko Metsä-Ketelä, Stephen Eric Nybo
Diverse Combinatorial Biosynthesis Strategies for C-H Functionalization of Anthracyclinones. ACS synthetic biology 13 (5) (2024)
Elnaz Jalali, Fengbin Wang, Brooke R Overbay, Mitchell D Miller, Khaled A Shaaban, Larissa V Ponomareva, Qing Ye, Hoda Saghaeiannejad-Esfahani, Minakshi Bhardwaj, Andrew D Steele, Christiana N Teijaro, Ben Shen, Steven G Van Lanen, Qing-Bai She, S Randal Voss, George N Phillips, Jon S Thorson
Biochemical and Structural Studies of the Carminomycin 4- O -Methyltransferase DnrK. Journal of natural products (2024)
Elnaz Jalali, Fengbin Wang, Brooke R Overbay, Mitchell D Miller, Khaled A Shaaban, Larissa V Ponomareva, Qing Ye, Hoda Saghaeiannejad-Esfahani, Minakshi Bhardwaj, Andrew D Steele, Christiana N Teijaro, Ben Shen, Steven G Van Lanen, Qing-Bai She, S Randal Voss, George N Phillips, Jon S Thorson
Biochemical and Structural Studies of the Carminomycin 4- O -Methyltransferase DnrK. Journal of natural products 87 (4) (2024)
Elnaz Jalali, Fengbin Wang, Brooke R Overbay, Mitchell D Miller, Khaled A Shaaban, Larissa V Ponomareva, Qing Ye, Hoda Saghaeiannejad-Esfahani, Minakshi Bhardwaj, Andrew D Steele, Christiana N Teijaro, Ben Shen, Steven G Van Lanen, Qing-Bai She, S Randal Voss, George N Phillips, Jon S Thorson
Biochemical and Structural Studies of the Carminomycin 4- O -Methyltransferase DnrK. Journal of natural products 87 (4) (2024)
Rongbin Wang, Benjamin Nji Wandi, Nora Schwartz, Jacob Hecht, Larissa Ponomareva, Kendall Paige, Alexis West, Kathryn Desanti, Jennifer Nguyen, Jarmo Niemi, Jon S Thorson, Khaled A Shaaban, Mikko Metsä-Ketelä, Stephen Eric Nybo
Diverse Combinatorial Biosynthesis Strategies for C-H Functionalization of Anthracyclinones. ACS synthetic biology 13 (5) (2024)
Rongbin Wang, Benjamin Nji Wandi, Nora Schwartz, Jacob Hecht, Larissa Ponomareva, Kendall Paige, Alexis West, Kathryn Desanti, Jennifer Nguyen, Jarmo Niemi, Jon S Thorson, Khaled A Shaaban, Mikko Metsä-Ketelä, Stephen Eric Nybo
Diverse Combinatorial Biosynthesis Strategies for C-H Functionalization of Anthracyclinones. ACS synthetic biology (2024)
Rongbin Wang, Benjamin Nji Wandi, Nora Schwartz, Jacob Hecht, Larissa Ponomareva, Kendall Paige, Alexis West, Kathryn Desanti, Jennifer Nguyen, Jarmo Niemi, Jon S Thorson, Khaled A Shaaban, Mikko Metsä-Ketelä, Stephen Eric Nybo
Diverse Combinatorial Biosynthesis Strategies for C-H Functionalization of Anthracyclinones. ACS synthetic biology 13 (5) (2024)
Rongbin Wang, Benjamin Nji Wandi, Nora Schwartz, Jacob Hecht, Larissa Ponomareva, Kendall Paige, Alexis West, Kathryn Desanti, Jennifer Nguyen, Jarmo Niemi, Jon S Thorson, Khaled A Shaaban, Mikko Metsä-Ketelä, Stephen Eric Nybo
Diverse Combinatorial Biosynthesis Strategies for C-H Functionalization of Anthracyclinones. ACS synthetic biology 13 (5) (2024)
Heli Tirkkonen, Katelyn V Brown, Magdalena Niemczura, Zélie Faudemer, Courtney Brown, Larissa V Ponomareva, Yosra A Helmy, Jon S Thorson, Stephen Eric Nybo, Mikko Metsä-Ketelä, Khaled A Shaaban
Engineering BioBricks for Deoxysugar Biosynthesis and Generation of New Tetracenomycins. ACS omega 8 (23) (2023)
Rongbin Wang, Jennifer Nguyen, Jacob Hecht, Nora Schwartz, Katelyn V Brown, Larissa V Ponomareva, Magdalena Niemczura, Dino van Dissel, Gilles P van Wezel, Jon S Thorson, Mikko Metsä-Ketelä, Khaled A Shaaban, Stephen Eric Nybo
A BioBricks Metabolic Engineering Platform for the Biosynthesis of Anthracyclinones in Streptomyces coelicolor . ACS synthetic biology (2022)
Abigael J Kosgei, Mitchell D Miller, Minakshi Bhardwaj, Weijun Xu, Jon S Thorson, Steven G Van Lanen, George N Philips
The crystal structure of DynF from the dynemicin-biosynthesis pathway of Micromonospora chersina. Acta crystallographica. Section F, Structural biology communications 78 (Pt 1) (2022)
Mohsin T Cheema, Larissa V Ponomareva, Tao Liu, S Randal Voss, Jon S Thorson, Khaled A Shaaban, Imran Sajid
Taxonomic and Metabolomics Profiling of Actinobacteria Strains from Himalayan Collection Sites in Pakistan. Current microbiology 78 (8) (2021)
Zheng Cui, Han Nguyen, Minakshi Bhardwaj, Xia-Chang Wang, Martin Büschleb, Anke Lemke, Christian Schütz, Christian Rohrbacher, Pierre Junghanns, Stefan Koppermann, Christian Ducho, Jon S Thorson, Steven G Van Lanen
Enzymatic Cβ-H Functionalization of l-Arg and l-Leu in Nonribosomally Derived Peptidyl Natural Products: A Tale of Two Oxidoreductases. Journal of the American Chemical Society 143 (46) (2021)
Jonathan A Clinger, Yi-Nan Zhang, Yang Liu, Mitchell D Miller, Ronnie E Hall, Steven G Van Lanen, George N Phillips, Jon S Thorson, Sherif I Elshahawi
Structure and Function of a Dual Reductase-Dehydratase Enzyme System Involved in p-Terphenyl Biosynthesis. ACS chemical biology (2021)
Yongyong Zhang, Mohsin T Cheema, Larissa V Ponomareva, Qing Ye, Tao Liu, Imran Sajid, Jürgen Rohr, Qing-Bai She, S Randal Voss, Jon S Thorson, Khaled A Shaaban
Himalaquinones A-G, Angucyclinone-Derived Metabolites Produced by the Himalayan Isolate Streptomyces sp. PU-MM59. Journal of natural products 84 (7) (2021)
Sarah K Alvarado, Mitchell D Miller, Minakshi Bhardwaj, Jon S Thorson, Steven G Van Lanen, George N Philips
Structural characterization of DynU16, a START/Bet v1-like protein involved in dynemicin biosynthesis. Acta crystallographica. Section F, Structural biology communications 77 (Pt 10) (2021)
Essam M Eliwa, Marcel Frese, Ahmed H Halawa, Maha M Soltan, Larissa V Ponomareva, Jon S Thorson, Khaled A Shaaban, Mohamed Shaaban, Ahmed M El-Agrody, Norbert Sewald
Metal-free domino amination-Knoevenagel condensation approach to access new coumarins as potent nanomolar inhibitors of VEGFR-2 and EGFR. Green chemistry letters and reviews 14 (4) (2021)
Tyler D Huber, Jonathan A Clinger, Yang Liu, Weijun Xu, Mitchell D Miller, George N Phillips, Jon S Thorson
Methionine Adenosyltransferase Engineering to Enable Bioorthogonal Platforms for AdoMet-Utilizing Enzymes. ACS chemical biology 15 (3) (2020)
Yi-Nan Zhang, Jianjun Zhang, Larissa V Ponomareva, Zheng Cui, Steven G Van Lanen, Jon S Thorson
Sugar-Pirating as an Enabling Platform for the Synthesis of 4,6-Dideoxyhexoses. Journal of the American Chemical Society 142 (20) (2020)
Yang Liu, Joseph M Eckenrode, Yi-Nan Zhang, Jianjun Zhang, Reiya C Hayden, Annet Kyomuhangi, Larissa V Ponomareva, Zheng Cui, Jürgen Rohr, Oleg V Tsodikov, Steven G Van Lanen, Khaled A Shaaban, Markos Leggas, Jon S Thorson
Mithramycin 2'-Oximes with Improved Selectivity, Pharmacokinetics, and Ewing Sarcoma Antitumor Efficacy. Journal of medicinal chemistry 63 (22) (2020)
Yi-Nan Zhang, Qing Ye, Larissa V Ponomareva, Yanan Cao, Yang Liu, Zheng Cui, Steven G Van Lanen, S Randal Voss, Qing-Bai She, Jon S Thorson
Total synthesis of griseusins and elucidation of the griseusin mechanism of action. Chemical science 10 (32) (2019)
Ryan R Hughes, Khaled A Shaaban, Larissa V Ponomareva, Jamie Horn, Chunhui Zhang, Chang-Guo Zhan, S Randal Voss, Markos Leggas, Jon S Thorson
OleD Loki as a Catalyst for Hydroxamate Glycosylation. Chembiochem : a European journal of chemical biology 21 (7) (2019)
Xia-Chang Wang, Sherif I Elshahawi, Larissa V Ponomareva, Qing Ye, Yang Liu, Gregory C Copley, James C Hower, Bruce E Hatcher, Madan K Kharel, Steven G Van Lanen, Qing-Bai She, S Randal Voss, Jon S Thorson, Khaled A Shaaban
Structure Determination, Functional Characterization, and Biosynthetic Implications of Nybomycin Metabolites from a Mining Reclamation Site-Associated Streptomyces. Journal of natural products 82 (12) (2019)
Xia-Chang Wang, Muhammad Abbas, Yi-Nan Zhang, Sherif I Elshahawi, Larissa V Ponomareva, Zheng Cui, Steven G Van Lanen, Imran Sajid, S Randal Voss, Khaled A Shaaban, Jon S Thorson
Baraphenazines A-G, Divergent Fused Phenazine-Based Metabolites from a Himalayan Streptomyces. Journal of natural products 82 (6) (2019)
Muhammad Abbas, Sherif I Elshahawi, Xia-Chang Wang, Larissa V Ponomareva, Imran Sajid, Khaled A Shaaban, Jon S Thorson
Puromycins B-E, Naturally Occurring Amino-Nucleosides Produced by the Himalayan Isolate Streptomyces sp. PU-14G. Journal of natural products 81 (11) (2018)
Stefan Koppermann, Zheng Cui, Patrick D Fischer, Xia-Chang Wang, Jannine Ludwig, Jon S Thorson, Steven G Van Lanen, Christian Ducho
Insights into the Target Interaction of Naturally Occurring Muraymycin Nucleoside Antibiotics. ChemMedChem 13 (8) (2018)
Zheng Cui, Xia-Chang Wang, Stefan Koppermann, Jon S Thorson, Christian Ducho, Steven G Van Lanen
Antibacterial Muraymycins from Mutant Strains of Streptomyces sp. NRRL 30471. Journal of natural products 81 (4) (2018)
Zheng Cui, Xiaodong Liu, Jonathan Overbay, Wenlong Cai, Xia-Chang Wang, Anke Lemke, Daniel Wiegmann, Giuliana Niro, Jon S Thorson, Christian Ducho, Steven G Van Lanen
Enzymatic Synthesis of the Ribosylated Glycyl-Uridine Disaccharide Core of Peptidyl Nucleoside Antibiotics. The Journal of organic chemistry 83 (13) (2018)
Xia-Chang Wang, Sherif I Elshahawi, Wenlong Cai, Yinan Zhang, Larissa V Ponomareva, Xiabin Chen, Gregory C Copley, James C Hower, Chang-Guo Zhan, Sean Parkin, Jürgen Rohr, Steven G Van Lanen, Khaled A Shaaban, Jon S Thorson
Bi- and Tetracyclic Spirotetronates from the Coal Mine Fire Isolate Streptomyces sp. LC-6-2. Journal of natural products 80 (4) (2017)
Xia-Chang Wang, Yinan Zhang, Larissa V Ponomareva, Qingchao Qiu, Ryan Woodcock, Sherif I Elshahawi, Xiabin Chen, Ziyuan Zhou, Bruce E Hatcher, James C Hower, Chang-Guo Zhan, Sean Parkin, Madan K Kharel, S Randal Voss, Khaled A Shaaban, Jon S Thorson
Mccrearamycins A-D, Geldanamycin-Derived Cyclopentenone Macrolactams from an Eastern Kentucky Abandoned Coal Mine Microbe. Angewandte Chemie (International ed. in English) 56 (11) (2017)
Jianjun Zhang, Ryan R Hughes, Meredith A Saunders, Sherif I Elshahawi, Larissa V Ponomareva, Yinan Zhang, Sydney R Winchester, Samantha A Scott, Manjula Sunkara, Andrew J Morris, Mark A Prendergast, Khaled A Shaaban, Jon S Thorson
Identification of Neuroprotective Spoxazomicin and Oxachelin Glycosides via Chemoenzymatic Glycosyl-Scanning. Journal of natural products 80 (1) (2016)
Khaled A Shaaban, Meredith A Saunders, Yinan Zhang, Tuan Tran, Sherif I Elshahawi, Larissa V Ponomareva, Xiachang Wang, Jianjun Zhang, Gregory C Copley, Manjula Sunkara, Madan K Kharel, Andrew J Morris, James C Hower, Matthew S Tremblay, Mark A Prendergast, Jon S Thorson
Spoxazomicin D and Oxachelin C, Potent Neuroprotective Carboxamides from the Appalachian Coal Fire-Associated Isolate Streptomyces sp. RM-14-6. Journal of natural products 80 (1) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Jon S Thorson