Scott Keeney

ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 50

Top Venues

bioRxiv : the preprint server for biology

Nature

Nature communications

Genes & development

Howard Hughes Medical Institute

University of California Berkeley (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Howard Hughes Medical Institute

United States

Investigator

Memorial Sloan-Kettering Cancer Center

United States

Member/Professor :: Molecular Biology

Harvard University

United States

Postdoctoral Fellow :: Biochemistry

Education History

University of California Berkeley

United States

PHD :: Biochemistry

Virginia Polytechnic Institute and State University

United States

BSC :: Biochemistry

Publications

Soonjoung Kim, Shintaro Yamada, Tao Li, Claudia Canasto-Chibuque, Jun Hyun Kim, Marina Marcet-Ortega, Jiaqi Xu, Diana Y Eng, Laura Feeney, John H J Petrini, Scott Keeney
The MRE11-RAD50-NBS1 complex both starts and extends DNA end resection in mouse meiosis. bioRxiv : the preprint server for biology (2024)
Soonjoung Kim, Shintaro Yamada, Tao Li, Claudia Canasto-Chibuque, Jun Hyun Kim, Marina Marcet-Ortega, Jiaqi Xu, Diana Y Eng, Laura Feeney, John H J Petrini, Scott Keeney
The MRE11-RAD50-NBS1 complex both starts and extends DNA end resection in mouse meiosis. bioRxiv : the preprint server for biology (2024)
You Yu, Juncheng Wang, Kaixian Liu, Zhi Zheng, Meret Arter, Corentin Claeys Bouuaert, Stephen Pu, Dinshaw J Patel, Scott Keeney
Cryo-EM structures of the Spo11 core complex bound to DNA. Nature structural & molecular biology (2024)
Pei-Ching Huang, Soogil Hong, Eleni P Mimitou, Keun Pil Kim, Hajime Murakami, Scott Keeney
Meiotic DNA break resection and recombination rely on chromatin remodeler Fun30. bioRxiv : the preprint server for biology (2024)
Soonjoung Kim, Shintaro Yamada, Kaku Maekawa, Scott Keeney
Optimized methods for mapping DNA double-strand-break ends and resection tracts and application to meiotic recombination in mouse spermatocytes. bioRxiv : the preprint server for biology (2024)
Soonjoung Kim, Shintaro Yamada, Tao Li, Claudia Canasto-Chibuque, Jun Hyun Kim, Marina Marcet-Ortega, Jiaqi Xu, Diana Y Eng, Laura Feeney, John H J Petrini, Scott Keeney
The MRE11-RAD50-NBS1 complex both starts and extends DNA end resection in mouse meiosis. bioRxiv : the preprint server for biology (2024)
Pei-Ching Huang, Soogil Hong, Eleni P Mimitou, Keun Pil Kim, Hajime Murakami, Scott Keeney
Meiotic DNA break resection and recombination rely on chromatin remodeler Fun30. bioRxiv : the preprint server for biology (2024)
Soonjoung Kim, Shintaro Yamada, Kaku Maekawa, Scott Keeney
Optimized methods for mapping DNA double-strand-break ends and resection tracts and application to meiotic recombination in mouse spermatocytes. bioRxiv : the preprint server for biology (2024)
Kaixian Liu, Emily M Grasso, Stephen Pu, Shixin Liu, David Eliezer, Scott Keeney
Structure and DNA bridging activity of the essential Rec114â€"Mei4 trimer interface. bioRxiv : the preprint server for biology (2023)
Jiaqi Xu, Tao Li, Soonjoung Kim, Michiel Boekhout, Scott Keeney
Essential roles of the ANKRD31-REC114 interaction in meiotic recombination and mouse spermatogenesis. bioRxiv : the preprint server for biology (2023)
Kaixian Liu, Emily M Grasso, Stephen Pu, Shixin Liu, David Eliezer, Scott Keeney
Structure and DNA bridging activity of the essential Rec114â€"Mei4 trimer interface. bioRxiv : the preprint server for biology (2023)
Jiaqi Xu, Tao Li, Soonjoung Kim, Michiel Boekhout, Scott Keeney
Essential roles of the ANKRD31-REC114 interaction in meiotic recombination and mouse spermatogenesis. bioRxiv : the preprint server for biology (2023)
Kaixian Liu, Emily M Grasso, Stephen Pu, Shixin Liu, David Eliezer, Scott Keeney
Structure and DNA bridging activity of the essential Rec114â€"Mei4 trimer interface. bioRxiv : the preprint server for biology (2023)
Kaixian Liu, Emily M Grasso, Stephen Pu, Shixin Liu, David Eliezer, Scott Keeney
Structure and DNA bridging activity of the essential Rec114â€"Mei4 trimer interface. bioRxiv : the preprint server for biology (2023)
Jiaqi Xu, Tao Li, Soonjoung Kim, Michiel Boekhout, Scott Keeney
Essential roles of the ANKRD31-REC114 interaction in meiotic recombination and mouse spermatogenesis. Proceedings of the National Academy of Sciences of the United States of America 120 (47) (2023)
Meret Arter, Scott Keeney
Divergence and conservation of the meiotic recombination machinery. Nature reviews. Genetics (2023)
You Yu, Juncheng Wang, Kaixian Liu, Zhi Zheng, Meret Arter, Corentin Claeys Bouuaert, Stephen Pu, Dinshaw J Patel, Scott Keeney
Cryo-EM structure of the Spo11 core complex bound to DNA. bioRxiv : the preprint server for biology (2023)
Jiaqi Xu, Tao Li, Soonjoung Kim, Michiel Boekhout, Scott Keeney
Essential roles of the ANKRD31-REC114 interaction in meiotic recombination and mouse spermatogenesis. bioRxiv : the preprint server for biology (2023)
Kaixian Liu, Emily M Grasso, Stephen Pu, Shixin Liu, David Eliezer, Scott Keeney
Structure and DNA bridging activity of the essential Rec114â€"Mei4 trimer interface. bioRxiv : the preprint server for biology (2023)
Kaixian Liu, Emily M Grasso, Stephen Pu, Mengyang Zou, Shixin Liu, David Eliezer, Scott Keeney
Structure and DNA-bridging activity of the essential Rec114-Mei4 trimer interface. Genes & development (2023)
Jiaqi Xu, Tao Li, Soonjoung Kim, Michiel Boekhout, Scott Keeney
Essential roles of the ANKRD31-REC114 interaction in meiotic recombination and mouse spermatogenesis. bioRxiv : the preprint server for biology (2023)
Kaku Maekawa, Shintaro Yamada, Rahul Sharma, Jayanta Chaudhuri, Scott Keeney
Triple-helix potential of the mouse genome. Proceedings of the National Academy of Sciences of the United States of America 119 (19) (2022)
Yuhki Saito, Ben R Hawley, M Rhyan Puno, Shreya N Sarathy, Christopher D Lima, Samie R Jaffrey, Robert B Darnell, Scott Keeney, Devanshi Jain
YTHDC2 control of gametogenesis requires helicase activity but not m 6 A binding. Genes & development 36 (3-4) (2022)
Yongjuan Guan, Scott Keeney, Devanshi Jain, P Jeremy Wang
yama, a mutant allele of Mov10l1, disrupts retrotransposon silencing and piRNA biogenesis. PLoS genetics 17 (2) (2021)
Ian R Humphreys, Jimin Pei, Minkyung Baek, Aditya Krishnakumar, David Baker, Sergey Ovchinnikov, Jing Zhang, Travis J Ness, Sudeep Banjade, Saket Rahul Bagde, Viktoriya G Stancheva, Xiao-Han Li, Kaixian Liu, Zhi Zheng, Daniel J Barrero, Upasana Roy, Jochen Kuper, Israel S Fernández, Barnabas Szakal, Dana Branzei, Josep Rizo, Caroline Kisker, Eric C Greene, Sue Biggins, Scott Keeney, Elizabeth A Miller, J Christopher Fromme, Tamara L Hendrickson, Nick V Grishin, Julien S Baker
Computed structures of core eukaryotic protein complexes. Science (New York, N.Y.) 374 (6573) (2021)
Corentin Claeys Bouuaert, Sam E Tischfield, Stephen Pu, Eleni P Mimitou, Ernesto Arias-Palomo, James M Berger, Scott Keeney
Structural and functional characterization of the Spo11 core complex. Nature structural & molecular biology 28 (1) (2021)
Hajime Murakami, Xiaojing Mu, Scott Keeney
How do small chromosomes know they are small? Maximizing meiotic break formation on the shortest yeast chromosomes. Current genetics 67 (3) (2021)
Corentin Claeys Bouuaert, Stephen Pu, Juncheng Wang, Cédric A Oger, Dima Daccache, Wei Xie, Dinshaw J Patel, Scott Keeney
DNA-driven condensation assembles the meiotic DNA break machinery. Nature 592 (7852) (2021)
Dominic Johnson, Margaret Crawford, Tim Cooper, Corentin Claeys Bouuaert, Scott Keeney, Bertrand Llorente, Valerie Garcia, Matthew J Neale
Concerted cutting by Spo11 illuminates meiotic DNA break mechanics. Nature 594 (7864) (2021)
Aurore Sanchez, Céline Adam, Felix Rauh, Yann Duroc, Lepakshi Ranjha, Berangere Lombard, Xiaojing Mu, Mélody Wintrebert, Damarys Loew, Alba Guarné, Stefano Gnan, Chun-Long Chen, Scott Keeney, Petr Cejka, Raphaël Guérois, Franz Klein, Jean-Baptiste Charbonnier, Valérie Borde
Exo1 recruits Cdc5 polo kinase to MutLγ to ensure efficient meiotic crossover formation. Proceedings of the National Academy of Sciences of the United States of America 117 (48) (2020)
Xiaojing Mu, Hajime Murakami, Neeman Mohibullah, Scott Keeney
Chromosome-autonomous feedback down-regulates meiotic DNA break competence upon synaptonemal complex formation. Genes & development 34 (23-24) (2020)
Hajime Murakami, Isabel Lam, Pei-Ching Huang, Jacquelyn Song, Megan van Overbeek, Scott Keeney
Multilayered mechanisms ensure that short chromosomes recombine in meiosis. Nature 582 (7810) (2020)
Shintaro Yamada, Anjali Gupta Hinch, Hisashi Kamido, Yongwei Zhang, Winfried Edelmann, Scott Keeney
Molecular structures and mechanisms of DNA break processing in mouse meiosis. Genes & development 34 (11-12) (2020)
Cynthia Petrillo, Vilma Barroca, Jonathan Ribeiro, Nathalie Lailler, Gabriel Livera, Scott Keeney, Emmanuelle Martini, Devanshi Jain
shani mutation in mouse affects splicing of Spata22 and leads to impaired meiotic recombination. Chromosoma 129 (2) (2020)
Laurent Acquaviva, Michiel Boekhout, Mehmet E Karasu, Kevin Brick, Florencia Pratto, Tao Li, Megan van Overbeek, Liisa Kauppi, R Daniel Camerini-Otero, Maria Jasin, Scott Keeney
Ensuring meiotic DNA break formation in the mouse pseudoautosomal region. Nature 582 (7812) (2020)
Vijayalakshmi V Subramanian, Xuan Zhu, Tovah E Markowitz, Luis Andre Vale-Silva, Pedro A San-Segundo, Nancy M Hollingsworth, Scott Keeney, Andreas Hochwagen
Persistent DNA-break potential near telomeres increases initiation of meiotic recombination on short chromosomes. Nature communications 10 (1) (2019)
Mehmet E Karasu, Nora Bouftas, Scott Keeney, Katja Wassmann
Cyclin B3 promotes anaphase I onset in oocyte meiosis. The Journal of cell biology 218 (4) (2019)
Mehmet E Karasu, Scott Keeney
Cyclin B3 is dispensable for mouse spermatogenesis. Chromosoma 128 (3) (2019)
Carla M C Abreu, Rohit Prakash, Peter J Romanienko, Ignasi Roig, Scott Keeney, Maria Jasin
Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination. Nature communications 9 (1) (2018)
Alexander Widger, Shantha K Mahadevaiah, Julian Lange, Elias ElInati, Jasmin Zohren, Takayuki Hirota, Sarai Pacheco, Andros Maldonado-Linares, Marcello Stanzione, Obah Ojarikre, Valdone Maciulyte, Dirk G de Rooij, Attila Tóth, Ignasi Roig, Scott Keeney, James M A Turner
ATR is a multifunctional regulator of male mouse meiosis. Nature communications 9 (1) (2018)
Sarai Pacheco, Andros Maldonado-Linares, Marina Marcet-Ortega, Cristina Rojas, Ana Martínez-Marchal, Judit Fuentes-Lazaro, Julian Lange, Maria Jasin, Scott Keeney, Oscar Fernández-Capetillo, Montserrat Garcia-Caldés, Ignasi Roig
ATR is required to complete meiotic recombination in mice. Nature communications 9 (1) (2018)
Devanshi Jain, M Rhyan Puno, Cem Meydan, Nathalie Lailler, Christopher E Mason, Christopher D Lima, Kathryn V Anderson, Scott Keeney
ketu mutant mice uncover an essential meiotic function for the ancient RNA helicase YTHDC2. eLife 7 (2018)
Agnieszka Lukaszewicz, Julian Lange, Scott Keeney, Maria Jasin
Control of meiotic double-strand-break formation by ATM: local and global views. Cell cycle (Georgetown, Tex.) 17 (10) (2018)
Devanshi Jain, Cem Meydan, Julian Lange, Corentin Claeys Bouuaert, Nathalie Lailler, Christopher E Mason, Kathryn V Anderson, Scott Keeney
rahu is a mutant allele of Dnmt3c, encoding a DNA methyltransferase homolog required for meiosis and transposon repression in the mouse male germline. PLoS genetics 13 (8) (2017)
Marina Marcet-Ortega, Sarai Pacheco, Ana Martínez-Marchal, Helena Castillo, Elsa Flores, Maria Jasin, Scott Keeney, Ignasi Roig
p53 and TAp63 participate in the recombination-dependent pachytene arrest in mouse spermatocytes. PLoS genetics 13 (6) (2017)
Corentin Claeys Bouuaert, Scott Keeney
Distinct DNA-binding surfaces in the ATPase and linker domains of MutLγ determine its substrate specificities and exert separable functions in meiotic recombination and mismatch repair. PLoS genetics 13 (5) (2017)
Shintaro Yamada, Seoyoung Kim, Sam E Tischfield, Maria Jasin, Julian Lange, Scott Keeney
Genomic and chromatin features shaping meiotic double-strand break formation and repair in mice. Cell cycle (Georgetown, Tex.) 16 (20) (2017)
Ryan Kniewel, Hajime Murakami, Yan Liu, Masaru Ito, Kunihiro Ohta, Nancy M Hollingsworth, Scott Keeney
Histone H3 Threonine 11 Phosphorylation Is Catalyzed Directly by the Meiosis-Specific Kinase Mek1 and Provides a Molecular Readout of Mek1 Activity in Vivo. Genetics 207 (4) (2017)
Marcello Stanzione, Marek Baumann, Frantzeskos Papanikos, Ihsan Dereli, Julian Lange, Angelique Ramlal, Daniel Tränkner, Hiroki Shibuya, Bernard de Massy, Yoshinori Watanabe, Maria Jasin, Scott Keeney, Attila Tóth
Meiotic DNA break formation requires the unsynapsed chromosome axis-binding protein IHO1 (CCDC36) in mice. Nature cell biology 18 (11) (2016)
Neeman Mohibullah, Scott Keeney
Numerical and spatial patterning of yeast meiotic DNA breaks by Tel1. Genome research 27 (2) (2016)
Nadine Vincenten, Lisa-Marie Kuhl, Isabel Lam, Ashwini Oke, Alastair R W Kerr, Andreas Hochwagen, Jennifer Fung, Scott Keeney, Gerben Vader, Adèle L Marston
The kinetochore prevents centromere-proximal crossover recombination during meiosis. eLife 4 (2015)
Xuan Zhu, Scott Keeney
High-Resolution Global Analysis of the Influences of Bas1 and Ino4 Transcription Factors on Meiotic DNA Break Distributions in Saccharomyces cerevisiae. Genetics 201 (2) (2015)

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Publication Activity (10 Years)

Top Topics

Top Venues

Scott Keeney