Juerg Schwaller (Jürg Schwaller)

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 27

Top Venues

UKBB Universitäts-Kinderspital

This page only lists publications with an associated author ORCID identifier.

Affiliation History

UKBB Universitäts-Kinderspital

Switzerland

Research group leader :: Biomedicine

Publications

Thomas Mercher, Juerg Schwaller
From hypoxia single-cell gene signatures to HIF targeting of AML leukemic stem cells. HemaSphere 8 (3) (2024)
Hannah Lawson, James P Holt-Martyn, Vilma Dembitz, Yuka Kabayama, Lydia M Wang, Aarushi Bellani, Samanpreet Atwal, Nadia Saffoon, Jozef Durko, Louie N van de Lagemaat, Azzura L De Pace, Anthony Tumber, Thomas P Corner, Eidarus Salah, Christine Arndt, Lennart Brewitz, Matthew J Bowen, Louis Dubusse, Derek George, Lewis Allen, Amélie Valérie Guitart, Tsz Kan Fung, Chi Wai Eric So, Juerg Schwaller, Paolo Gallipoli, Donal O'Carroll, Christopher J Schofield, Kamil R Kranc
The selective prolyl hydroxylase inhibitor IOX5 stabilizes HIF-1α and compromises development and progression of acute myeloid leukemia. Nature cancer 5 (6) (2024)
Hannah Lawson, James P Holt-Martyn, Vilma Dembitz, Yuka Kabayama, Lydia M Wang, Aarushi Bellani, Samanpreet Atwal, Nadia Saffoon, Jozef Durko, Louie N van de Lagemaat, Azzura L De Pace, Anthony Tumber, Thomas P Corner, Eidarus Salah, Christine Arndt, Lennart Brewitz, Matthew J Bowen, Louis Dubusse, Derek George, Lewis Allen, Amélie Valérie Guitart, Tsz Kan Fung, Chi Wai Eric So, Juerg Schwaller, Paolo Gallipoli, Donal O'Carroll, Christopher J Schofield, Kamil R Kranc
The selective prolyl hydroxylase inhibitor IOX5 stabilizes HIF-1α and compromises development and progression of acute myeloid leukemia. Nature cancer 5 (6) (2024)
Hannah Lawson, James P Holt-Martyn, Vilma Dembitz, Yuka Kabayama, Lydia M Wang, Aarushi Bellani, Samanpreet Atwal, Nadia Saffoon, Jozef Durko, Louie N van de Lagemaat, Azzura L De Pace, Anthony Tumber, Thomas P Corner, Eidarus Salah, Christine Arndt, Lennart Brewitz, Matthew J Bowen, Louis Dubusse, Derek George, Lewis Allen, Amélie Valérie Guitart, Tsz Kan Fung, Chi Wai Eric So, Juerg Schwaller, Paolo Gallipoli, Donal O'Carroll, Christopher J Schofield, Kamil R Kranc
The selective prolyl hydroxylase inhibitor IOX5 stabilizes HIF-1α and compromises development and progression of acute myeloid leukemia. Nature cancer 5 (6) (2024)
Alexandre Fagnan, Zakia Aid, Marie Baille, Aneta Drakul, Elie Robert, Cécile K Lopez, Cécile Thirant, Yann Lecluse, Julie Rivière, Cathy Ignacimouttou, Silvia Salmoiraghi, Eduardo Anguita, Audrey Naimo, Christophe Marzac, Françoise Pflumio, Sébastien Malinge, Christian Wichmann, Yun Huang, Camille Lobry, Julie Chaumeil, Eric Soler, Jean-Pierre Bourquin, Claus Nerlov, Olivier A Bernard, Juerg Schwaller, Thomas Mercher
The ETO2 transcriptional cofactor maintains acute leukemia by driving a MYB/EP300-dependent stemness program. HemaSphere 8 (6) (2024)
Hannah Lawson, James P Holt-Martyn, Vilma Dembitz, Yuka Kabayama, Lydia M Wang, Aarushi Bellani, Samanpreet Atwal, Nadia Saffoon, Jozef Durko, Louie N van de Lagemaat, Azzura L De Pace, Anthony Tumber, Thomas P Corner, Eidarus Salah, Christine Arndt, Lennart Brewitz, Matthew J Bowen, Louis Dubusse, Derek George, Lewis Allen, Amélie Valérie Guitart, Tsz Kan Fung, Chi Wai Eric So, Juerg Schwaller, Paolo Gallipoli, Donal O'Carroll, Christopher J Schofield, Kamil R Kranc
The selective prolyl hydroxylase inhibitor IOX5 stabilizes HIF-1α and compromises development and progression of acute myeloid leukemia. Nature cancer (2024)
Thomas Mercher, Juerg Schwaller
From hypoxia single-cell gene signatures to HIF targeting of AML leukemic stem cells. HemaSphere 8 (3) (2024)
Julien M P Grenier, Céline Testut, Matthieu Bal, Florence Bardin, Maria De Grandis, Véronique Gelsi-Boyer, Julien Vernerey, Marjorie Delahaye, Samuel Granjeaud, Christophe Zemmour, Jean-François Spinella, Triantafyllos Chavakis, Stéphane J C Mancini, Jean-Marie Boher, Josée Hébert, Guy Sauvageau, Norbert Vey, Juerg Schwaller, Marie-Anne Hospital, Cyril Fauriat, Michel A Aurrand-Lions
Genetic deletion of JAM-C in preleukemic cells rewires leukemic stem cell gene expression program in AML. Blood advances 8 (17) (2024)
Hannah Lawson, James P Holt-Martyn, Vilma Dembitz, Yuka Kabayama, Lydia M Wang, Aarushi Bellani, Samanpreet Atwal, Nadia Saffoon, Jozef Durko, Louie N van de Lagemaat, Azzura L De Pace, Anthony Tumber, Thomas P Corner, Eidarus Salah, Christine Arndt, Lennart Brewitz, Matthew J Bowen, Louis Dubusse, Derek George, Lewis Allen, Amélie Valérie Guitart, Tsz Kan Fung, Chi Wai Eric So, Juerg Schwaller, Paolo Gallipoli, Donal O'Carroll, Christopher J Schofield, Kamil R Kranc
The selective prolyl hydroxylase inhibitor IOX5 stabilizes HIF-1α and compromises development and progression of acute myeloid leukemia. Nature cancer 5 (6) (2024)
Julien M P Grenier, Céline Testut, Matthieu Bal, Florence Bardin, Maria De Grandis, Véronique Gelsi-Boyer, Julien Vernerey, Marjorie Delahaye, Samuel Granjeaud, Christophe Zemmour, Jean-François Spinella, Triantafyllos Chavakis, Stéphane J C Mancini, Jean-Marie Boher, Josée Hébert, Guy Sauvageau, Norbert Vey, Juerg Schwaller, Marie-Anne Hospital, Cyril Fauriat, Michel A Aurrand-Lions
Genetic deletion of JAM-C in preleukemic cells rewires leukemic stem cell gene expression program in AML. Blood advances 8 (17) (2024)
Vilma Dembitz, Hannah Lawson, Richard Burt, Sirisha Natani, Céline Philippe, Sophie C James, Samantha Atkinson, Jozef Durko, Lydia M Wang, Joana Campos, Aoife M S Magee, Keith Woodley, Michael James Austin, Ana Rio-Machin, Pedro Casado, Findlay Bewicke-Copley, Giovanny Rodriguez Blanco, Diego Pereira-Martins, Lieve Oudejans, Emeline Boet, Alex von Kriegsheim, Juerg Schwaller, Andrew J Finch, Bela Patel, Jean-Emmanuel Sarry, Jerome Tamburini, Jan Jacob Schuringa, Lori Hazlehurst, John A Copland Iii, Mariia Yuneva, Barrie Peck, Pedro Rodriguez Cutillas, Jude Fitzgibbon, Kevin Rouault-Pierre, Kamil R Kranc, Paolo Gallipoli
Stearoyl-CoA desaturase inhibition is toxic to acute myeloid leukemia displaying high levels of the de novo fatty acid biosynthesis and desaturation. Leukemia (2024)
Julien M P Grenier, Céline Testut, Matthieu Bal, Florence Bardin, Maria De Grandis, Véronique Gelsi-Boyer, Julien Vernerny, Marjorie C Delahaye, Samuel Granjeaud, Christophe Zemmour, Jean-François Spinella, Triantafyllos Chavakis, Stephane Jc Mancini, Jean-Marie Boher, Josée Hébert, Guy Sauvageau, Norbert Vey, Juerg Schwaller, Marie-Anne Hospital, Cyril Fauriat, Michel A Aurrand-Lions
Genetic deletion of JAM-C in pre-leukemic cells rewires leukemic stem cell gene expression program in AML. Blood advances (2024)
Alexandre Fagnan, Zakia Aid, Marie Baille, Aneta Drakul, Elie Robert, Cécile K Lopez, Cécile Thirant, Yann Lecluse, Julie Rivière, Cathy Ignacimouttou, Silvia Salmoiraghi, Eduardo Anguita, Audrey Naimo, Christophe Marzac, Françoise Pflumio, Sébastien Malinge, Christian Wichmann, Yun Huang, Camille Lobry, Julie Chaumeil, Eric Soler, Jean-Pierre Bourquin, Claus Nerlov, Olivier A Bernard, Juerg Schwaller, Thomas Mercher
The ETO2 transcriptional cofactor maintains acute leukemia by driving a MYB/EP300-dependent stemness program. HemaSphere 8 (6) (2024)
Hannah Lawson, James P Holt-Martyn, Vilma Dembitz, Yuka Kabayama, Lydia M Wang, Aarushi Bellani, Samanpreet Atwal, Nadia Saffoon, Jozef Durko, Louie N van de Lagemaat, Azzura L De Pace, Anthony Tumber, Thomas P Corner, Eidarus Salah, Christine Arndt, Lennart Brewitz, Matthew J Bowen, Louis Dubusse, Derek George, Lewis Allen, Amélie Valérie Guitart, Tsz Kan Fung, Chi Wai Eric So, Juerg Schwaller, Paolo Gallipoli, Donal O'Carroll, Christopher J Schofield, Kamil R Kranc
The selective prolyl hydroxylase inhibitor IOX5 stabilizes HIF-1α and compromises development and progression of acute myeloid leukemia. Nature cancer (2024)
Elizabeth Heyes, Anna S Wilhelmson, Anne Wenzel, Gabriele Manhart, Thomas Eder, Mikkel B Schuster, Edwin Rzepa, Sachin Pundhir, Teresa D'Altri, Anne-Katrine Frank, Coline Gentil, Jakob Woessmann, Erwin M Schoof, Manja Meggendorfer, Juerg Schwaller, Torsten Haferlach, Florian Grebien, Bo Torben Porse
TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression. Nature communications 14 (1) (2023)
Maria-Riera Piqué-Borràs, Zivojin Jevtic, Frederik Otzen Bagger, Jonathan Seguin, Rathick Sivalingam, Matheus Filgueira Bezerra, Amber Louwaige, Sabine Juge, Ioannis Nellas, Robert Ivanek, Alexandar Tzankov, Ute Moll, Oriano Valerio Cantillo, Ramona Schultz-Heddergott, Alexandre Fagnan, Thomas Mercher, Juerg Schwaller
The NFIA-ETO2 fusion blocks erythroid maturation and induces pure erythroid leukemia in cooperation with mutant TP53. Blood (2023)
Seemon Coomar, Pedro Mota, Alexander V Penson, Juerg Schwaller, Omar Abdel-Wahab, Dennis Gillingham
Overlaid Transcriptional and Proteome Analyses Identify Mitotic Kinesins as Important Targets of Arylsulfonamide-Mediated RBM39 Degradation. Molecular cancer research : MCR (2023)
Maria-Riera Piqué-Borràs, Zivojin Jevtic, Frederik Otzen Bagger, Jonathan Seguin, Rathick Sivalingam, Matheus Filgueira Bezerra, Amber Louwaige, Sabine Juge, Ioannis Nellas, Robert Ivanek, Alexandar Tzankov, Ute Moll, Oriano Valerio Cantillo, Ramona Schultz-Heddergott, Alexandre Fagnan, Thomas Mercher, Juerg Schwaller
The NFIA-ETO2 fusion blocks erythroid maturation and induces pure erythroid leukemia in cooperation with mutant TP53. Blood (2023)
Seemon Coomar, Pedro Mota, Alexander V Penson, Juerg Schwaller, Omar Abdel-Wahab, Dennis Gillingham
Overlaid transcriptome and proteome analyses identify mitotic kinesins as important targets of arylsulfonamide-mediated RBM39 degradation. Molecular cancer research : MCR (2023)
Maria-Riera Piqué-Borràs, Zivojin Jevtic, Frederik Otzen Bagger, Jonathan Seguin, Rathick Sivalingam, Matheus Filgueira Bezerra, Amber Louwaige, Sabine Juge, Ioannis Nellas, Robert Ivanek, Alexandar Tzankov, Ute Moll, Oriano Valerio Cantillo, Ramona Schultz-Heddergott, Alexandre Fagnan, Thomas Mercher, Juerg Schwaller
The NFIA-ETO2 fusion blocks erythroid maturation and induces pure erythroid leukemia in cooperation with mutant TP53. Blood (2023)
Juerg Schwaller
High-mobility-group protein A1 in MPN progression. Blood 139 (18) (2022)
Juerg Schwaller
MLL-AF4+ infant leukemia: a microRNA affair. Blood 138 (21) (2021)
Samantha Tauchmann, Juerg Schwaller
NSD1: A Lysine Methyltransferase between Developmental Disorders and Cancer. Life (Basel, Switzerland) 11 (9) (2021)
Samantha Tauchmann, Marwa Almosailleakh, Juerg Schwaller
NSD1 in erythroid differentiation and leukemogenesis. Molecular & cellular oncology 7 (6) (2020)
Katharina Leonards, Marwa Almosailleakh, Samantha Tauchmann, Frederik Otzen Bagger, Cécile Thirant, Sabine Juge, Thomas Bock, Hélène Méreau, Matheus Filgueira Bezerra, Alexandar Tzankov, Robert Ivanek, Régine Losson, Antoine H F M Peters, Thomas Mercher, Juerg Schwaller
Nuclear interacting SET domain protein 1 inactivation impairs GATA1-regulated erythroid differentiation and causes erythroleukemia. Nature communications 11 (1) (2020)
Cécile K Lopez, Esteve Noguera, Vaia Stavropoulou, Elie Robert, Zakia Aid, Paola Ballerini, Chrystèle Bilhou-Nabera, Hélène Lapillonne, Fabien Boudia, Cécile Thirant, Alexandre Fagnan, Marie-Laure Arcangeli, Sarah J Kinston, M'Boyba Diop, Bastien Job, Yann Lecluse, Erika Brunet, Loélia Babin, Jean Luc Villeval, Eric Delabesse, Antoine H F M Peters, William Vainchenker, Muriel Gaudry, Riccardo Masetti, Franco Locatelli, Sebastien Malinge, Claus Nerlov, Nathalie M Droin, Camille Lobry, Isabelle Godin, Olivier A Bernard, Berthold Göttgens, Arnaud Petit, Françoise Pflumio, Juerg Schwaller, Thomas Mercher
Ontogenic Changes in Hematopoietic Hierarchy Determine Pediatric Specificity and Disease Phenotype in Fusion Oncogene-Driven Myeloid Leukemia. Cancer discovery 9 (12) (2019)
Sara El Ashkar, Juerg Schwaller, Tim Pieters, Steven Goossens, Jonas Demeulemeester, Frauke Christ, Siska Van Belle, Sabine Juge, Nancy Boeckx, Alan Engelman, Pieter Van Vlierberghe, Zeger Debyser, Jan De Rijck
LEDGF/p75 is dispensable for hematopoiesis but essential for MLL-rearranged leukemogenesis. Blood 131 (1) (2017)

Juerg Schwaller.css-eqlu8i{font-size:small;padding-left:4px;} (Jürg Schwaller)

Publication Activity (10 Years)

Top Topics

Top Venues

Juerg Schwaller (Jürg Schwaller)