Paolo Gallipoli (P Gallipoli)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 25

Top Topics

Acute Myeloid Leukemia

Oxidative Stress

Top Venues

Science translational medicine

This page only lists publications with an associated author ORCID identifier.

Publications

Hannah Lawson, James P Holt-Martyn, Vilma Dembitz, Yuka Kabayama, Lydia M Wang, Aarushi Bellani, Samanpreet Atwal, Nadia Saffoon, Jozef Durko, Louie N van de Lagemaat, Azzura L De Pace, Anthony Tumber, Thomas P Corner, Eidarus Salah, Christine Arndt, Lennart Brewitz, Matthew J Bowen, Louis Dubusse, Derek George, Lewis Allen, Amélie Valérie Guitart, Tsz Kan Fung, Chi Wai Eric So, Juerg Schwaller, Paolo Gallipoli, Donal O'Carroll, Christopher J Schofield, Kamil R Kranc
The selective prolyl hydroxylase inhibitor IOX5 stabilizes HIF-1α and compromises development and progression of acute myeloid leukemia. Nature cancer 5 (6) (2024)
Hannah Lawson, James P Holt-Martyn, Vilma Dembitz, Yuka Kabayama, Lydia M Wang, Aarushi Bellani, Samanpreet Atwal, Nadia Saffoon, Jozef Durko, Louie N van de Lagemaat, Azzura L De Pace, Anthony Tumber, Thomas P Corner, Eidarus Salah, Christine Arndt, Lennart Brewitz, Matthew J Bowen, Louis Dubusse, Derek George, Lewis Allen, Amélie Valérie Guitart, Tsz Kan Fung, Chi Wai Eric So, Juerg Schwaller, Paolo Gallipoli, Donal O'Carroll, Christopher J Schofield, Kamil R Kranc
The selective prolyl hydroxylase inhibitor IOX5 stabilizes HIF-1α and compromises development and progression of acute myeloid leukemia. Nature cancer 5 (6) (2024)
Vilma Dembitz, Jozef Durko, Joana Campos, Sophie C James, Hannah Lawson, Kamil R Kranc, Paolo Gallipoli
Immunodeficient NBSGW mouse strain allows chemotherapy modeling in AML patient-derived xenografts. HemaSphere 8 (1) (2024)
Vilma Dembitz, Jozef Durko, Joana Campos, Sophie C James, Hannah Lawson, Kamil R Kranc, Paolo Gallipoli
Immunodeficient NBSGW mouse strain allows chemotherapy modeling in AML patient-derived xenografts. HemaSphere 8 (1) (2024)
Hannah Lawson, James P Holt-Martyn, Vilma Dembitz, Yuka Kabayama, Lydia M Wang, Aarushi Bellani, Samanpreet Atwal, Nadia Saffoon, Jozef Durko, Louie N van de Lagemaat, Azzura L De Pace, Anthony Tumber, Thomas P Corner, Eidarus Salah, Christine Arndt, Lennart Brewitz, Matthew J Bowen, Louis Dubusse, Derek George, Lewis Allen, Amélie Valérie Guitart, Tsz Kan Fung, Chi Wai Eric So, Juerg Schwaller, Paolo Gallipoli, Donal O'Carroll, Christopher J Schofield, Kamil R Kranc
The selective prolyl hydroxylase inhibitor IOX5 stabilizes HIF-1α and compromises development and progression of acute myeloid leukemia. Nature cancer 5 (6) (2024)
Hannah Lawson, James P Holt-Martyn, Vilma Dembitz, Yuka Kabayama, Lydia M Wang, Aarushi Bellani, Samanpreet Atwal, Nadia Saffoon, Jozef Durko, Louie N van de Lagemaat, Azzura L De Pace, Anthony Tumber, Thomas P Corner, Eidarus Salah, Christine Arndt, Lennart Brewitz, Matthew J Bowen, Louis Dubusse, Derek George, Lewis Allen, Amélie Valérie Guitart, Tsz Kan Fung, Chi Wai Eric So, Juerg Schwaller, Paolo Gallipoli, Donal O'Carroll, Christopher J Schofield, Kamil R Kranc
The selective prolyl hydroxylase inhibitor IOX5 stabilizes HIF-1α and compromises development and progression of acute myeloid leukemia. Nature cancer (2024)
Andrew J Innes, Chloe Hayden, Victoria Orovboni, Simone Claudiani, Fiona Fernando, Afzal Khan, David Rees, Jennifer Byrne, Paolo Gallipoli, Sebastian Francis, Mhairi Copland, Gillian A Horne, Manoj Raghavan, Claire Arnold, Angela Collins, Tanya Cranfield, Nicholas Cunningham, Akila Danga, Peter Forsyth, Rebecca Frewin, Paula Garland, Guy Hannah, Daniele Avenoso, Sandra Hassan, Brian James Patrick Huntly, Jissan Husain, Sudhakaran Makkuni, Kate Rothwell, Jamshid Khorashad, Jane F Apperley, Dragana Milojkovic
Impact of BCR::ABL1 single nucleotide variants on asciminib efficacy. Leukemia (2024)
Hannah Lawson, James P Holt-Martyn, Vilma Dembitz, Yuka Kabayama, Lydia M Wang, Aarushi Bellani, Samanpreet Atwal, Nadia Saffoon, Jozef Durko, Louie N van de Lagemaat, Azzura L De Pace, Anthony Tumber, Thomas P Corner, Eidarus Salah, Christine Arndt, Lennart Brewitz, Matthew J Bowen, Louis Dubusse, Derek George, Lewis Allen, Amélie Valérie Guitart, Tsz Kan Fung, Chi Wai Eric So, Juerg Schwaller, Paolo Gallipoli, Donal O'Carroll, Christopher J Schofield, Kamil R Kranc
The selective prolyl hydroxylase inhibitor IOX5 stabilizes HIF-1α and compromises development and progression of acute myeloid leukemia. Nature cancer 5 (6) (2024)
Vilma Dembitz, Hannah Lawson, Richard Burt, Sirisha Natani, Céline Philippe, Sophie C James, Samantha Atkinson, Jozef Durko, Lydia M Wang, Joana Campos, Aoife M S Magee, Keith Woodley, Michael James Austin, Ana Rio-Machin, Pedro Casado, Findlay Bewicke-Copley, Giovanny Rodriguez Blanco, Diego Pereira-Martins, Lieve Oudejans, Emeline Boet, Alex von Kriegsheim, Juerg Schwaller, Andrew J Finch, Bela Patel, Jean-Emmanuel Sarry, Jerome Tamburini, Jan Jacob Schuringa, Lori Hazlehurst, John A Copland Iii, Mariia Yuneva, Barrie Peck, Pedro Rodriguez Cutillas, Jude Fitzgibbon, Kevin Rouault-Pierre, Kamil R Kranc, Paolo Gallipoli
Stearoyl-CoA desaturase inhibition is toxic to acute myeloid leukemia displaying high levels of the de novo fatty acid biosynthesis and desaturation. Leukemia (2024)
Vilma Dembitz, Jozef Durko, Joana Campos, Sophie C James, Hannah Lawson, Kamil R Kranc, Paolo Gallipoli
Immunodeficient NBSGW mouse strain allows chemotherapy modeling in AML patient-derived xenografts. HemaSphere 8 (1) (2024)
Hannah Lawson, James P Holt-Martyn, Vilma Dembitz, Yuka Kabayama, Lydia M Wang, Aarushi Bellani, Samanpreet Atwal, Nadia Saffoon, Jozef Durko, Louie N van de Lagemaat, Azzura L De Pace, Anthony Tumber, Thomas P Corner, Eidarus Salah, Christine Arndt, Lennart Brewitz, Matthew J Bowen, Louis Dubusse, Derek George, Lewis Allen, Amélie Valérie Guitart, Tsz Kan Fung, Chi Wai Eric So, Juerg Schwaller, Paolo Gallipoli, Donal O'Carroll, Christopher J Schofield, Kamil R Kranc
The selective prolyl hydroxylase inhibitor IOX5 stabilizes HIF-1α and compromises development and progression of acute myeloid leukemia. Nature cancer (2024)
Syed A Mian, Céline Philippe, Eleni Maniati, Pantelitsa Protopapa, Tiffany Bergot, Marion Piganeau, Travis Nemkov, Doriana Di Bella, Valle Morales, Andrew J Finch, Angelo D'Alessandro, Katiuscia Bianchi, Jun Wang, Paolo Gallipoli, Shahram Kordasti, Anne Sophie Kubasch, Michael Cross, Uwe Platzbecker, Daniel H Wiseman, Dominique Bonnet, Delphine G. Bernard, John G Gribben, Kevin Rouault-Pierre
Vitamin B5 and succinyl-CoA improve ineffective erythropoiesis in SF3B1 -mutated myelodysplasia. Science translational medicine 15 (685) (2023)
Marie Sabatier, Rudy Birsen, Laura Lauture, Sarah Mouche, Paolo Angelino, Jonas Dehairs, Lea Goupille, Ismael Boussaid, Mael Heiblig, Emeline Boet, Ambrine Sahal, Estelle Saland, Juliana Carvalho Santos, Marc Armengol, Miranda Fernandez-Serrano, Thomas Farge, Guillaume Cognet, Federico Simonetta, Corentin Pignon, Antoine Graffeuil, Celine Mazzotti, Herve Avet-Loiseau, Oceane Delos, Justine Bertrand-Michel, Amelie Chedru, Vilma Dembitz, Paolo Gallipoli, Natasha S Anstee, Sun Loo, Andrew H Wei, Martin P Carroll, Armelle Goubard, Rémy Castellano, Yves Collette, François Vergez, Véronique De Mas, Sarah Bertoli, Suzanne Tavitian, Muriel Picard, Christian Recher, Nathalie H Bourgès-Abella, Fanny Granat, Olivier Kosmider, Pierre Sujobert, Benoit Colsch, Carine Joffre, Lucille Stuani, Johannes V Swinnen, Hervé Guillou, Gael Roué, Nawad Hakim, Anne S Dejean, Petros K Tsantoulis, Clément Larrue, Didier Bouscary, Jérome Tamburini, Jean-Emmanuel Sarry
C/EBPa confers dependence to fatty acid anabolic pathways and vulnerability to lipid oxidative stress-induced ferroptosis in FLT3-mutant leukemia. Cancer discovery (2023)
Syed A Mian, Céline Philippe, Eleni Maniati, Pantelitsa Protopapa, Tiffany Bergot, Marion Piganeau, Travis Nemkov, Doriana Di Bella, Valle Morales, Andrew J Finch, Angelo D'Alessandro, Katiuscia Bianchi, Jun Wang, Paolo Gallipoli, Shahram Kordasti, Anne Sophie Kubasch, Michael Cross, Uwe Platzbecker, Daniel H Wiseman, Dominique Bonnet, Delphine G. Bernard, John G Gribben, Kevin Rouault-Pierre
Vitamin B5 and succinyl-CoA improve ineffective erythropoiesis in SF3B1 -mutated myelodysplasia. Science translational medicine 15 (685) (2023)
Syed A Mian, Céline Philippe, Eleni Maniati, Pantelitsa Protopapa, Tiffany Bergot, Marion Piganeau, Travis Nemkov, Doriana Di Bella, Valle Morales, Andrew J Finch, Angelo D'Alessandro, Katiuscia Bianchi, Jun Wang, Paolo Gallipoli, Shahram Kordasti, Anne Sophie Kubasch, Michael Cross, Uwe Platzbecker, Daniel H Wiseman, Dominique Bonnet, Delphine G. Bernard, John G Gribben, Kevin Rouault-Pierre
Vitamin B5 and succinyl-CoA improve ineffective erythropoiesis in SF3B1 -mutated myelodysplasia. Science translational medicine 15 (685) (2023)
Keith Woodley, Laura S Dillingh, George Giotopoulos, Pedro Madrigal, Kevin M Rattigan, Céline Philippe, Vilma Dembitz, Aoife M S Magee, Ryan Asby, Louie N van de Lagemaat, Christopher Mapperley, Sophie C James, Jochen H M Prehn, Konstantinos Tzelepis, Kevin Rouault-Pierre, George S Vassiliou, Kamil R Kranc, G Vignir Helgason, Brian James Patrick Huntly, Paolo Gallipoli
Mannose metabolism inhibition sensitizes acute myeloid leukaemia cells to therapy by driving ferroptotic cell death. Nature communications 14 (1) (2023)
Mark A Dawson, Gautam Borthakur, Brian James Patrick Huntly, Anastasios Karadimitris, Adrian Alegre, Aristeidis Chaidos, Dan T Vogl, Daniel A Pollyea, Faith E Davies, Gareth J Morgan, Jacob Lowell Glass, Manali Kamdar, Maria-Victoria Mateos-Manteca, Natalia Tovar, Paul Yeh, Regina García Delgado, Faisal Basheer, Ludovica Marando, Paolo Gallipoli, Anastasia Wyce, Anu Shilpa Krishnatry, Olena Barbash, Evi Bakirtzi, Geraldine Ferron-Brady, Natalie O Karpinich, Michael T McCabe, Shawn W Foley, Thierry Horner, Arindam Dhar, Brandon E Kremer, Michael J Dickinson
A phase I/II open-label study of molibresib for the treatment of relapsed/refractory hematologic malignancies. Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Paolo Gallipoli
AML gets upSET when its dietary needs are unMet. Blood 140 (19) (2022)
Paolo Gallipoli, Richard E Clark, Jenny Byrne, Jane F Apperley, Dragana Milojkovic, Letizia Foroni, John M Goldman, Stephen O'Brien
The UK SPIRIT 1 trial in newly diagnosed chronic myeloid leukaemia. British journal of haematology 196 (6) (2022)
Haiyang Yun, Nisha Narayan, Shabana Vohra, George Giotopoulos, Annalisa Mupo, Pedro Madrigal, Daniel Sasca, David Lara-Astiaso, Sarah J Horton, Shuchi Agrawal-Singh, Eshwar Meduri, Faisal Basheer, Ludovica Marando, Malgorzata Gozdecka, Oliver M Dovey, Aracely Castillo-Venzor, Xiaonan Wang, Paolo Gallipoli, Carsten Muller-Tidow, Cameron S Osborne, George S Vassiliou, Brian James Patrick Huntly
Mutational synergy during leukemia induction remodels chromatin accessibility, histone modifications and three-dimensional DNA topology to alter gene expression. Nature genetics 53 (10) (2021)
Gillian A Horne, J Stobo, C Kelly, A Mukhopadhyay, A L Latif, J Dixon-Hughes, L McMahon, P Cony-Makhoul, Jennifer L Byrne, G Smith, Steffen Koschmieder, T H BrÜmmendorf, P Schafhausen, Paolo Gallipoli, F Thomson, W Cong, R E Clark, D Milojkovic, G V Helgason, L Foroni, F E Nicolini, T L Holyoake, Mhairi Copland
A randomised phase II trial of hydroxychloroquine and imatinib versus imatinib alone for patients with chronic myeloid leukaemia in major cytogenetic response with residual disease. Leukemia 34 (7) (2020)
Faisal Basheer, George Giotopoulos, Eshwar Meduri, Haiyang Yun, Milena Mazan, Daniel Sasca, Paolo Gallipoli, Ludovica Marando, Malgorzata Gozdecka, Ryan J Asby, Olivia Sheppard, Monika Dudek, Lars Bullinger, Hartmut Döhner, Richard Dillon, Sylvie Freeman, Oliver Ottmann, Alan Burnett, Nigel Russell, Elli Papaemmanuil, Robert Hills, Peter Campbell, George S Vassiliou, Brian James Patrick Huntly
Contrasting requirements during disease evolution identify EZH2 as a therapeutic target in AML. The Journal of experimental medicine 216 (4) (2019)
Paolo Gallipoli, George Giotopoulos, Konstantinos Tzelepis, Ana S H Costa, Shabana Vohra, Paula Medina-Perez, Faisal Basheer, Ludovica Marando, Lorena Di Lisio, Joao M L Dias, Haiyang Yun, Daniel Sasca, Sarah J Horton, George Vassiliou, Christian Frezza, Brian James Patrick Huntly
Glutaminolysis is a metabolic dependency in FLT3ITD acute myeloid leukemia unmasked by FLT3 tyrosine kinase inhibition. Blood 131 (15) (2018)
Konstantinos Tzelepis, Etienne De Braekeleer, Demetrios Aspris, Isaia Barbieri, M S Vijayabaskar, Wen-Hsin Liu, Malgorzata Gozdecka, Emmanouil Metzakopian, Hamish D Toop, Monika Dudek, Samuel C Robson, Francisco Hermida-Prado, Yu Hsuen Yang, Roya Babaei-Jadidi, Dimitrios A Garyfallos, Hannes Ponstingl, Joao M L Dias, Paolo Gallipoli, Michael Seiler, Silvia Buonamici, Binje Vick, Andrew J Bannister, Roland Rad, Rabinder K Prinjha, John C Marioni, Brian James Patrick Huntly, Jennifer Batson, Jonathan C Morris, Cristina Pina, Allan Bradley, Irmela Jeremias, David O Bates, Kosuke Yusa, Tony Kouzarides, George S Vassiliou
SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4. Nature communications 9 (1) (2018)
Anuradha Tarafdar, Lisa E M Hopcroft, Paolo Gallipoli, Francesca Pellicano, Jennifer Cassels, Alan Hair, Koorosh Korfi, Heather G Jørgensen, David Vetrie, Tessa L Holyoake, Alison M Michie
CML cells actively evade host immune surveillance through cytokine-mediated downregulation of MHC-II expression. Blood 129 (2) (2016)