Juho J Miettinen

Publication Activity (10 Years)

Years Active: 2021-2024
Publications (10 Years): 15

Top Topics

Acute Myeloid Leukemia

Peritoneal Dialysis

Multiple Myeloma

Network Analysis

Top Venues

Signal transduction and targeted therapy

This page only lists publications with an associated author ORCID identifier.

Publications

Mehdi Mirzaie, Elham Gholizadeh, Juho J Miettinen, Filipp Ianevski, Tanja Ruokoranta, Jani Saarela, Mikko Manninen, Susanna Miettinen, Caroline A Heckman, Mohieddin Jafari
Designing patient-oriented combination therapies for acute myeloid leukemia based on efficacy/toxicity integration and bipartite network modeling. Oncogenesis 13 (1) (2024)
Mehdi Mirzaie, Elham Gholizadeh, Juho J Miettinen, Filipp Ianevski, Tanja Ruokoranta, Jani Saarela, Mikko Manninen, Susanna Miettinen, Caroline A Heckman, Mohieddin Jafari
Designing patient-oriented combination therapies for acute myeloid leukemia based on efficacy/toxicity integration and bipartite network modeling. Oncogenesis 13 (1) (2024)
Katie Dunphy, Despina Bazou, Michael Henry, Paula Meleady, Juho J Miettinen, Caroline A Heckman, Paul Dowling, Peter O'Gorman
Proteomic and Metabolomic Analysis of Bone Marrow and Plasma from Patients with Extramedullary Multiple Myeloma Identifies Distinct Protein and Metabolite Signatures. Cancers 15 (15) (2023)
Pedro Casado, Ana Rio-Machin, Juho J Miettinen, Findlay Bewicke-Copley, Kevin Rouault-Pierre, Szilvia Krizsán, Alun Parsons, Vinothini Rajeeve, Farideh Miraki-Moud, David C Taussig, Csaba Bödör, John Gribben, Caroline A Heckman, Jude Fitzgibbon, Pedro Rodriguez Cutillas
Integrative phosphoproteomics defines two biologically distinct groups of KMT2A rearranged acute myeloid leukaemia with different drug response phenotypes. Signal transduction and targeted therapy 8 (1) (2023)
Pedro Casado, Ana Rio-Machin, Juho J Miettinen, Findlay Bewicke-Copley, Kevin Rouault-Pierre, Szilvia Krizsán, Alun Parsons, Vinothini Rajeeve, Farideh Miraki-Moud, David C Taussig, Csaba Bödör, John Gribben, Caroline A Heckman, Jude Fitzgibbon, Pedro Rodriguez Cutillas
Integrative phosphoproteomics defines two biologically distinct groups of KMT2A rearranged acute myeloid leukaemia with different drug response phenotypes. Signal transduction and targeted therapy 8 (1) (2023)
Yingjia Chen, Liye He, Aleksandr Ianevski, Pilar Ayuda-Durán, Swapnil Potdar, Jani Saarela, Juho J Miettinen, Sari Kytölä, Susanna Miettinen, Mikko Manninen, Caroline A Heckman, Jorrit M Enserink, Krister Wennerberg, Tero Aittokallio
Robust scoring of selective drug responses for patient-tailored therapy selection. Nature protocols (2023)
Pedro Casado, Ana Rio-Machin, Juho J Miettinen, Findlay Bewicke-Copley, Kevin Rouault-Pierre, Szilvia Krizsán, Alun Parsons, Vinothini Rajeeve, Farideh Miraki-Moud, David C Taussig, Csaba Bödör, John Gribben, Caroline A Heckman, Jude Fitzgibbon, Pedro Rodriguez Cutillas
Integrative phosphoproteomics defines two biologically distinct groups of KMT2A rearranged acute myeloid leukaemia with different drug response phenotypes. Signal transduction and targeted therapy 8 (1) (2023)
Pedro Casado, Ana Rio-Machin, Juho J Miettinen, Findlay Bewicke-Copley, Kevin Rouault-Pierre, Szilvia Krizsán, Alun Parsons, Vinothini Rajeeve, Farideh Miraki-Moud, David C Taussig, Csaba Bödör, John Gribben, Caroline A Heckman, Jude Fitzgibbon, Pedro Rodriguez Cutillas
Integrative phosphoproteomics defines two biologically distinct groups of KMT2A rearranged acute myeloid leukaemia with different drug response phenotypes. Signal transduction and targeted therapy 8 (1) (2023)
Heikki Kuusanmäki, Olli Dufva, Markus Vähä-Koskela, Aino-Maija Leppä, Jani Huuhtanen, Ida Maria Vänttinen, Petra Johanna Nygren, Jay Klievink, Jonas Otto Vilhelm Bouhlal, Petri Pölönen, Qi Zhang, Shady Adnan-Awad, Cristina Mancebo-Pérez, Joseph Saad, Juho J Miettinen, Komal Kumar Javarappa, Sofia Aakko, Tanja Ruokoranta, Samuli Eldfors, Merja Heinäniemi, Kim Theilgaard-Mönch, Ulla Wartiovaara-Kautto, Mikko A I Keränen, Kimmo Porkka, Marina Konopleva, Krister Wennerberg, Mika Kontro, Caroline A Heckman, Mohamed El Missiry
Erythroid/megakaryocytic differentiation confers BCL-XL dependency and venetoclax resistance in acute myeloid leukemia. Blood (2022)
Heikki Kuusanmäki, Olli Dufva, Markus Vähä-Koskela, Aino-Maija Leppä, Jani Huuhtanen, Ida Maria Vänttinen, Petra Johanna Nygren, Jay Klievink, Jonas Otto Vilhelm Bouhlal, Petri Pölönen, Qi Zhang, Shady Adnan-Awad, Cristina Mancebo-Pérez, Joseph Saad, Juho J Miettinen, Komal Kumar Javarappa, Sofia Aakko, Tanja Ruokoranta, Samuli Eldfors, Merja Heinäniemi, Kim Theilgaard-Mönch, Ulla Wartiovaara-Kautto, Mikko A I Keränen, Kimmo Porkka, Marina Konopleva, Krister Wennerberg, Mika Kontro, Caroline A Heckman, Mohamed El Missiry
Erythroid/megakaryocytic differentiation confers BCL-XL dependency and venetoclax resistance in acute myeloid leukemia. Blood (2022)
William Grey, Ana Rio-Machin, Pedro Casado, Eva Grönroos, Sara Ali, Juho J Miettinen, Findlay Bewicke-Copley, Alun Parsons, Caroline A Heckman, Charles Swanton, Pedro Rodriguez Cutillas, John G Gribben, Jude Fitzgibbon, Dominique Bonnet
CKS1 inhibition depletes leukemic stem cells and protects healthy hematopoietic stem cells in acute myeloid leukemia. Science translational medicine 14 (650) (2022)
Arjen Gebraad, Roope Ohlsbom, Juho J Miettinen, Promise Emeh, Toni-Karri Pakarinen, Mikko Manninen, Antti Eskelinen, Kirsi Kuismanen, Ana Slipicevic, Fredrik Lehmann, Nina N Nupponen, Caroline A Heckman, Susanna Miettinen
Growth Response and Differentiation of Bone Marrow-Derived Mesenchymal Stem/Stromal Cells in the Presence of Novel Multiple Myeloma Drug Melflufen. Cells 11 (9) (2022)
Juho J Miettinen, Romika Kumari, Gunnhildur Asta Traustadottir, Maiju-Emilia Huppunen, Philipp Sergeev, Muntasir M Majumder, Alexander Schepsky, Thorarinn Gudjonsson, Juha Lievonen, Despina Bazou, Paul Dowling, Peter O Gorman, Ana Slipicevic, Pekka Anttila, Raija Silvennoinen, Nina N Nupponen, Fredrik Lehmann, Caroline A Heckman
Aminopeptidase Expression in Multiple Myeloma Associates with Disease Progression and Sensitivity to Melflufen. Cancers 13 (7) (2021)
Paul Dowling, Ciara Tierney, Katie Dunphy, Juho J Miettinen, Caroline A Heckman, Despina Bazou, Peter O'Gorman
Identification of Protein Biomarker Signatures for Acute Myeloid Leukemia (AML) Using Both Nontargeted and Targeted Approaches. Proteomes 9 (4) (2021)
Arnold Bolomsky, Juho J Miettinen, Alina Malyutina, Andrej Besse, Julia Huber, Stefanie Fellinger, Helene Breid, Alun Parsons, Kristaps Klavins, J Thomas Hannich, Stefan Kubicek, Jo Caers, Wolfgang Hübl, Martin Schreder, Niklas Zojer, Christoph Driessen, Jing Tang, Lenka Besse, Caroline A Heckman, Heinz Ludwig
Heterogeneous modulation of Bcl-2 family members and drug efflux mediate MCL-1 inhibitor resistance in multiple myeloma. Blood advances 5 (20) (2021)