Stefan Kubicek

ResearcherID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 46

Top Venues

Nature communications

Nature chemical biology

Nature cell biology

Science (New York, N.Y.)

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences

Univeristy of Vienna (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences Aug 01 2010

Austria

Head, Chemical Screening :: Platform Austria for Chemical Biology PLACEBO

Broad Institute of Harvard and MIT Feb 01 2007 - Jul 31 2010

United States

Postdoctoral Fellow :: Schreiber Laboratory

The Research Institute of Molecular Pathology (IMP) Jul 01 2002 - Dec 31 2006

Austria

PhD Student/Postdoc :: Jenuwein Laboratory

ETH Zürich Feb 01 2001 - Aug 31 2001

Switzerland

Diploma Student :: Diederich Laboratory

Education History

Univeristy of Vienna Oct 01 2002 - Aug 01 2006

Austria

PHD :: Research Institute of Molecular Pathology (IMP)

Publications

Fabian Offensperger, Gary Tin, Miquel Duran-Frigola, Elisa Hahn, Sarah Dobner, Christopher W Am Ende, Joseph W Strohbach, Andrea Rukavina, Vincenth Brennsteiner, Kevin Ogilvie, Chakravarthy B N Marella, Katharina Kladnik, Rodolfo Ciuffa, Jaimeen D Majmudar, S Denise Field, Ariel Bensimon, Luca Ferrari, Evandro Ferrada, Amanda Ng, Zhechun Zhang, Gianluca Degliesposti, Andras Boeszoermenyi, Sascha Martens, Robert Stanton, André C Müller, J Thomas Hannich, David Hepworth, Giulio Superti-Furga, Stefan Kubicek, Monica Schenone, Georg E Winter
Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science (New York, N.Y.) 384 (6694) (2024)
Tayma Handal, Sarah Juster, Manar Abu Diab, Shira Yanovsky-Dagan, Fouad Zahdeh, Uria Aviel, Roni Sarel-Gallily, Shir Michael, Ester Bnaya, Shulamit Sebban, Yosef Buganim, Yotam Drier, Vincent Mouly, Stefan Kubicek, Walther J A A van den Broek, Derick G Wansink, Silvina Epsztejn-Litman, Rachel Eiges
Differentiation shifts from a reversible to an irreversible heterochromatin state at the DM1 locus. Nature communications 15 (1) (2024)
Andreas Reicher, Jiří Reiniš, Maria Ciobanu, Pavel Růžička, Monika Malik, Marton Siklos, Victoria Kartysh, Tatjana Tomek, Anna Koren, André F Rendeiro, Stefan Kubicek
Pooled multicolour tagging for visualizing subcellular protein dynamics. Nature cell biology 26 (5) (2024)
Chrysanthi Kagiou, Jose A Cisneros, Jakob Farnung, Joanna Liwocha, Fabian Offensperger, Kevin Dong, Ka Yang, Gary Tin, Christina S Horstmann, Matthias Hinterndorfer, Joao A Paulo, Natalie S Scholes, Juan Sanchez Avila, Michaela Fellner, Florian Andersch, J Thomas Hannich, Johannes Zuber, Stefan Kubicek, Steven P Gygi, Brenda A Schulman, Georg E Winter
Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation. Nature communications 15 (1) (2024)
Andreas Reicher, Jiří Reiniš, Maria Ciobanu, Pavel Růžička, Monika Malik, Marton Siklos, Victoria Kartysh, Tatjana Tomek, Anna Koren, André F Rendeiro, Stefan Kubicek
Pooled multicolour tagging for visualizing subcellular protein dynamics. Nature cell biology 26 (5) (2024)
Tayma Handal, Sarah Juster, Manar Abu Diab, Shira Yanovsky-Dagan, Fouad Zahdeh, Uria Aviel, Roni Sarel-Gallily, Shir Michael, Ester Bnaya, Shulamit Sebban, Yosef Buganim, Yotam Drier, Vincent Mouly, Stefan Kubicek, Walther J A A van den Broek, Derick G Wansink, Silvina Epsztejn-Litman, Rachel Eiges
Differentiation shifts from a reversible to an irreversible heterochromatin state at the DM1 locus. Nature communications 15 (1) (2024)
Chrysanthi Kagiou, Jose A Cisneros, Jakob Farnung, Joanna Liwocha, Fabian Offensperger, Kevin Dong, Ka Yang, Gary Tin, Christina S Horstmann, Matthias Hinterndorfer, Joao A Paulo, Natalie S Scholes, Juan Sanchez Avila, Michaela Fellner, Florian Andersch, J Thomas Hannich, Johannes Zuber, Stefan Kubicek, Steven P Gygi, Brenda A Schulman, Georg E Winter
Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation. Nature communications 15 (1) (2024)
Tayma Handal, Sarah Juster, Manar Abu Diab, Shira Yanovsky-Dagan, Fouad Zahdeh, Uria Aviel, Roni Sarel-Gallily, Shir Michael, Ester Bnaya, Shulamit Sebban, Yosef Buganim, Yotam Drier, Vincent Mouly, Stefan Kubicek, Walther J A A van den Broek, Derick G Wansink, Silvina Epsztejn-Litman, Rachel Eiges
Differentiation shifts from a reversible to an irreversible heterochromatin state at the DM1 locus. Nature communications 15 (1) (2024)
Andreas Reicher, Jiří Reiniš, Maria Ciobanu, Pavel Růžička, Monika Malik, Marton Siklos, Victoria Kartysh, Tatjana Tomek, Anna Koren, André F Rendeiro, Stefan Kubicek
Pooled multicolour tagging for visualizing subcellular protein dynamics. Nature cell biology 26 (5) (2024)
Andreas Reicher, Jiří Reiniš, Maria Ciobanu, Pavel Růžička, Monika Malik, Marton Siklos, Victoria Kartysh, Tatjana Tomek, Anna Koren, André F Rendeiro, Stefan Kubicek
Pooled multicolour tagging for visualizing subcellular protein dynamics. Nature cell biology (2024)
Andreas Reicher, Jiří Reiniš, Maria Ciobanu, Pavel Růžička, Monika Malik, Marton Siklos, Victoria Kartysh, Tatjana Tomek, Anna Koren, André F Rendeiro, Stefan Kubicek
Pooled multicolour tagging for visualizing subcellular protein dynamics. Nature cell biology 26 (5) (2024)
Fabian Offensperger, Gary Tin, Miquel Duran-Frigola, Elisa Hahn, Sarah Dobner, Christopher W Am Ende, Joseph W Strohbach, Andrea Rukavina, Vincenth Brennsteiner, Kevin Ogilvie, Chakravarthy B N Marella, Katharina Kladnik, Rodolfo Ciuffa, Jaimeen D Majmudar, S Denise Field, Ariel Bensimon, Luca Ferrari, Evandro Ferrada, Amanda Ng, Zhechun Zhang, Gianluca Degliesposti, Andras Boeszoermenyi, Sascha Martens, Robert Stanton, André C Müller, J Thomas Hannich, David Hepworth, Giulio Superti-Furga, Stefan Kubicek, Monica Schenone, Georg E Winter
Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science (New York, N.Y.) 384 (6694) (2024)
Tayma Handal, Sarah Juster, Manar Abu Diab, Shira Yanovsky-Dagan, Fouad Zahdeh, Uria Aviel, Roni Sarel-Gallily, Shir Michael, Ester Bnaya, Shulamit Sebban, Yosef Buganim, Yotam Drier, Vincent Mouly, Stefan Kubicek, Walther J A A van den Broek, Derick G Wansink, Silvina Epsztejn-Litman, Rachel Eiges
Differentiation shifts from a reversible to an irreversible heterochromatin state at the DM1 locus. Nature communications 15 (1) (2024)
Chrysanthi Kagiou, Jose A Cisneros, Jakob Farnung, Joanna Liwocha, Fabian Offensperger, Kevin Dong, Ka Yang, Gary Tin, Christina S Horstmann, Matthias Hinterndorfer, Joao A Paulo, Natalie S Scholes, Juan Sanchez Avila, Michaela Fellner, Florian Andersch, J Thomas Hannich, Johannes Zuber, Stefan Kubicek, Steven P Gygi, Brenda A Schulman, Georg E Winter
Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation. Nature communications 15 (1) (2024)
Chrysanthi Kagiou, Jose A Cisneros, Jakob Farnung, Joanna Liwocha, Fabian Offensperger, Kevin Dong, Ka Yang, Gary Tin, Christina S Horstmann, Matthias Hinterndorfer, Joao A Paulo, Natalie S Scholes, Juan Sanchez Avila, Michaela Fellner, Florian Andersch, J Thomas Hannich, Johannes Zuber, Stefan Kubicek, Steven P Gygi, Brenda A Schulman, Georg E Winter
Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation. Nature communications 15 (1) (2024)
Fabian Offensperger, Gary Tin, Miquel Duran-Frigola, Elisa Hahn, Sarah Dobner, Christopher W Am Ende, Joseph W Strohbach, Andrea Rukavina, Vincenth Brennsteiner, Kevin Ogilvie, Chakravarthy B N Marella, Katharina Kladnik, Rodolfo Ciuffa, Jaimeen D Majmudar, S Denise Field, Ariel Bensimon, Luca Ferrari, Evandro Ferrada, Amanda Ng, Zhechun Zhang, Gianluca Degliesposti, Andras Boeszoermenyi, Sascha Martens, Robert Stanton, André C Müller, J Thomas Hannich, David Hepworth, Giulio Superti-Furga, Stefan Kubicek, Monica Schenone, Georg E Winter
Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science (New York, N.Y.) 384 (6694) (2024)
Andras Boeszoermenyi, Léa Bernaleau, Xudong Chen, Felix Kartnig, Min Xie, Haobo Zhang, Sensen Zhang, Maeva Delacrétaz, Anna Koren, Ann-Katrin Hopp, Vojtech Dvorak, Stefan Kubicek, Daniel Aletaha, Maojun Yang, Manuele Rebsamen, Leonhard X Heinz, Giulio Superti-Furga
A conformation-locking inhibitor of SLC15A4 with TASL proteostatic anti-inflammatory activity. Nature communications 14 (1) (2023)
Lennart Enders, Marton Siklos, Jan Borggräfe, Stefan Gaussmann, Anna Koren, Monika Malik, Tatjana Tomek, Michael K Schuster, Jiří Reiniš, Elisa Hahn, Andrea Rukavina, Andreas Reicher, Tamara Casteels, Christoph Bock, Georg E Winter, J Thomas Hannich, Michael Sattler, Stefan Kubicek
Pharmacological perturbation of the phase-separating protein SMNDC1. Nature communications 14 (1) (2023)
Lena Hess, Verena Moos, Arnel A Lauber, Wolfgang Reiter, Michael Schuster, Natascha Hartl, Daniel Lackner, Thorina Boenke, Anna Koren, Paloma M Guzzardo, Brigitte Gundacker, Anna Riegler, Petra Vician, Claudia Miccolo, Susanna Leiter, Mahesh B Chandrasekharan, Terezia Vcelkova, Andrea Tanzer, Jun Qi Jun, James Bradner, Gerald Brosch, Markus Hartl, Christoph Bock, Tilmann Bürckstümmer, Stefan Kubicek, Susanna Chiocca, Srividya Bhaskara, Christian Seiser
A toolbox for class I HDACs reveals isoform specific roles in gene regulation and protein acetylation. PLoS genetics 18 (8) (2022)
Kartika Venugopal, Yang Feng, Pawel Nowialis, Huanzhou Xu, Daniil E Shabashvili, Cassandra M Berntsen, Prabhjot Kaur, Kathryn I Krajcik, Christina Taragjini, Zachary Zaroogian, Heidi L Casellas Román, Luisa M Posada, Chamara Gunaratne, Jianping Li, Daphné Dupéré-Richer, Richard L Bennett, Santhi Pondugula, Alberto Riva, Christopher R Cogle, Rene Opavsky, Brian K Law, Sumita Bhaduri-McIntosh, Stefan Kubicek, Philipp B Staber, Jonathan D Licht, Jonathan E Bird, Olga A Guryanova
DNMT3A Harboring Leukemia-Associated Mutations Directs Sensitivity to DNA Damage at Replication Forks. Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
Fabián Amaya-García, Michael Caldera, Anna Koren, Stefan Kubicek, J Formula See Text Rg Menche, Miriam M Unterlass
Green Hydrothermal Synthesis of Fluorescent 2,3-Diarylquinoxalines and Large-Scale Computational Comparison to Existing Alternatives. ChemSusChem 14 (8) (2021)
Sandra Schick, Sarah Grosche, Katharina Eva Kohl, Danica Drpic, Martin G Jaeger, Chakravarthy B N Marella, Hana Imrichova, Jung-Ming G Lin, Gerald Hofstätter, Michael K Schuster, André Figueiredo Rendeiro, Anna Koren, Mark Petronczki, Christoph Bock, André C Müller, Georg E Winter, Stefan Kubicek
Acute BAF perturbation causes immediate changes in chromatin accessibility. Nature genetics 53 (3) (2021)
Fabián Amaya-García, Michael Caldera, Anna Koren, Stefan Kubicek, J Formula See Text Rg Menche, Miriam M Unterlass
Green Hydrothermal Synthesis of Fluorescent 2,3-Diarylquinoxalines and Large-Scale Computational Comparison to Existing Alternatives. ChemSusChem 14 (8) (2021)
Marton Siklos, Stefan Kubicek
Therapeutic targeting of chromatin: status and opportunities. The FEBS journal (2021)
Ruochen Jia, Leon Kutzner, Anna Koren, Kathrin Runggatscher, Peter Májek, André C Müller, Michael K Schuster, Christoph Bock, Joanna I Loizou, Stefan Kubicek, Robert Kralovics
High-throughput drug screening identifies the ATR-CHK1 pathway as a therapeutic vulnerability of CALR mutated hematopoietic cells. Blood cancer journal 11 (7) (2021)
Christoph Kornauth, Tea Pemovska, Gregory I Vladimer, Günther Bayer, Michael M Bergmann, Sandra Eder, Ruth Eichner, Martin Erl, Harald Esterbauer, Ruth Exner, Verena Felsleitner-Hauer, Maurizio Forte, Alexander Gaiger, Klaus Geissler, Hildegard T Greinix, Wolfgang Gstöttner, Marcus Hacker, Bernd Lorenz Hartmann, Alexander W Hauswirth, Tim Heinemann, Daniel Heintel, Mir Alireza Hoda, Georg Hopfinger, Ulrich Jaeger, Lukas Kazianka, Lukas Kenner, Barbara Kiesewetter, Nikolaus Krall, Gerhard Krajnik, Stefan Kubicek, Trang Le, Simone Lubowitzki, Marius E Mayerhoefer, Elisabeth Menschel, Olaf Merkel, Katsuhiro Miura, Leonhard Müllauer, Peter Neumeister, Thomas Noesslinger, Katharina Ocko, Leopold Öhler, Michael Panny, Alexander Pichler, Edit Porpaczy, Gerald W Prager, Markus Raderer, Robin Ristl, Reinhard Ruckser, Julius Salamon, Ana-Iris Schiefer, Ann-Sofie Schmolke, Ilse Schwarzinger, Edgar Selzer, Christian Sillaber, Cathrin Skrabs, Wolfgang R Sperr, Ismet Srndic, Renate Thalhammer, Peter Valent, Emiel van der Kouwe, Katrina Vanura, Stefan Vogt, Cora Waldstein, Dominik Wolf, Christoph C Zielinski, Niklas Zojer, Ingrid Simonitsch-Klupp, Giulio Superti-Furga, Berend Snijder, Philipp B Staber
Functional Precision Medicine Provides Clinical Benefit in Advanced Aggressive Hematological Cancers and Identifies Exceptional Responders. Cancer discovery (2021)
Dimitrios Tsiantoulas, Mahya Eslami, Georg Obermayer, Marc Clement, Diede Smeets, Florian J Mayer, Máté G Kiss, Lennart Enders, Juliane Weißer, Laura Göderle, Jordi Lambert, Florian Frommlet, André Mueller, Tim Hendrikx, Maria Ozsvar-Kozma, Florentina Porsch, Laure Willen, Taras Afonyushkin, Jane E Murphy, Per Fogelstrand, Olivier Donzé, Gerard Pasterkamp, Matthias Hoke, Stefan Kubicek, Helle F Jørgensen, Nicolas Danchin, Tabassome Simon, Hubert Scharnagl, Winfried März, Jan Borén, Henry Hess, Ziad Mallat, Pascal Schneider, Christoph J Binder
APRIL limits atherosclerosis by binding to heparan sulfate proteoglycans. Nature 597 (7874) (2021)
Arnold Bolomsky, Juho J Miettinen, Alina Malyutina, Andrej Besse, Julia Huber, Stefanie Fellinger, Helene Breid, Alun Parsons, Kristaps Klavins, J Thomas Hannich, Stefan Kubicek, Jo Caers, Wolfgang Hübl, Martin Schreder, Niklas Zojer, Christoph Driessen, Jing Tang, Lenka Besse, Caroline A Heckman, Heinz Ludwig
Heterogeneous modulation of Bcl-2 family members and drug efflux mediate MCL-1 inhibitor resistance in multiple myeloma. Blood advances 5 (20) (2021)
Kai-Chun Li, Enrico Girardi, Felix Kartnig, Sarah Grosche, Tea Pemovska, Johannes W Bigenzahn, Ulrich Goldmann, Vitaly Sedlyarov, Ariel Bensimon, Sandra Schick, Jung-Ming G Lin, Bettina Gürtl, Daniela Reil, Kristaps Klavins, Stefan Kubicek, Sara Sdelci, Giulio Superti-Furga
Cell-surface SLC nucleoside transporters and purine levels modulate BRD4-dependent chromatin states. Nature metabolism 3 (5) (2021)
Andreas Reicher, Anna Koren, Stefan Kubicek
Pooled protein tagging, cellular imaging, and in situ sequencing for monitoring drug action in real time. Genome research 30 (12) (2020)
Enrico Girardi, Adrián César-Razquin, Sabrina Lindinger, Konstantinos Papakostas, Justyna Konecka, Jennifer Hemmerich, Stefanie Kickinger, Felix Kartnig, Bettina Gürtl, Kristaps Klavins, Vitaly Sedlyarov, Alvaro Ingles-Prieto, Giuseppe Fiume, Anna Koren, Charles-Hugues Lardeau, Richard Kumaran Kandasamy, Stefan Kubicek, Gerhard F Ecker, Giulio Superti-Furga
A widespread role for SLC transmembrane transporters in resistance to cytotoxic drugs. Nature chemical biology 16 (4) (2020)
Alexander Swoboda, Robert Soukup, Oliver Eckel, Katharina Kinslechner, Bettina Wingelhofer, David Schörghofer, Christina Sternberg, Ha T T Pham, Maria Vallianou, Jaqueline Horvath, Dagmar Stoiber, Lukas Kenner, Lionel Larue, Valeria Poli, Friedrich Beermann, Takashi Yokota, Stefan Kubicek, Thomas Krausgruber, André Figueiredo Rendeiro, Christoph Bock, Rainer Zenz, Boris Kovacic, Fritz Aberger, Markus Hengstschläger, Peter Petzelbauer, Mario Mikula, Richard H Moriggl
STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pathway. Oncogene 40 (6) (2020)
Christian Schmidl, Gregory I Vladimer, André Figueiredo Rendeiro, Susanne Schnabl, Thomas Krausgruber, Christina Taubert, Nikolaus Krall, Tea Pemovska, Mohammad Araghi, Berend Snijder, Rainer Hubmann, Anna Ringler, Kathrin Runggatscher, Dita Demirtas, Oscar Lopez de la Fuente, Martin Hilgarth, Cathrin Skrabs, Edit Porpaczy, Michaela Gruber, Gregor Hoermann, Stefan Kubicek, Philipp B Staber, Medhat Shehata, Giulio Superti-Furga, Ulrich Jäger, Christoph Bock
Combined chemosensitivity and chromatin profiling prioritizes drug combinations in CLL. Nature chemical biology 15 (3) (2019)
Sandra Schick, André Figueiredo Rendeiro, Kathrin Runggatscher, Anna Ringler, Bernd Boidol, Melanie Hinkel, Peter Májek, Loan Vulliard, Thomas Penz, Katja Parapatics, Christian Schmidl, J Formula See Text Rg Menche, Guido Boehmelt, Mark Petronczki, André C Müller, Christoph Bock, Stefan Kubicek
Systematic characterization of BAF mutations provides insights into intracomplex synthetic lethalities in human cancers. Nature genetics 51 (9) (2019)
Ingeborg Menzl, Tinghu Zhang, Angelika Berger-Becvar, Reinhard Grausenburger, Gerwin Heller, Michaela Prchal-Murphy, Leo Edlinger, Vanessa M Knab, Iris Z Uras, Eva Grundschober, Karin Bauer, Mareike Roth, Anna Skucha, Yao Liu, John M Hatcher, Yanke Liang, Nicholas P Kwiatkowski, Daniela Fux, Andrea Hoelbl-Kovacic, Stefan Kubicek, Junia V Melo, Peter Valent, Thomas Weichhart, Florian Grebien, Johannes Zuber, Nathanael S Gray, Veronika Sexl
A kinase-independent role for CDK8 in BCR-ABL1+ leukemia. Nature communications 10 (1) (2019)
Sara Sdelci, André Figueiredo Rendeiro, Philipp Rathert, Wanhui You, Jung-Ming G Lin, Anna Ringler, Gerald Hofstätter, Herwig P Moll, Bettina Gürtl, Matthias Farlik, Sandra Schick, Freya Klepsch, Matthew Oldach, Pisanu Buphamalai, Fiorella Schischlik, Peter Májek, Katja Parapatics, Christian Schmidl, Michael K Schuster, Thomas Penz, Dennis L Buckley, Otto Hudecz, Richard Imre, Shuang-Yan Wang, Hans Michael Maric, Robert Kralovics, Keiryn L Bennett, Andre C Müller, Karl Mechtler, J Formula See Text Rg Menche, James E Bradner, Georg E Winter, Kristaps Klavins, Emilio Casanova, Christoph Bock, Johannes Zuber, Stefan Kubicek
MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation. Nature genetics 51 (6) (2019)
Philipp Bernhard Staber, Marco Herling, Mar Bellido, Eric D Jacobsen, Matthew S Davids, Tapan Mahendra Kadia, Andrei Shustov, Olivier Tournilhac, Emmanuel Bachy, Francesco Zaja, Kimmo Porkka, Gregor Hoermann, Ingrid Simonitsch-Klupp, Claudia Haferlach, Stefan Kubicek, Marius E Mayerhoefer, Georg Hopfinger, Ulrich Jäger, Claire Dearden
Consensus criteria for diagnosis, staging, and treatment response assessment of T-cell prolymphocytic leukemia. Blood 134 (14) (2019)
Florian Bellutti, Anca-Sarmiza Tigan, Sofie Nebenfuehr, Marlies Dolezal, Markus Zojer, Reinhard Grausenburger, Svenja Hartenberger, Sebastian Kollmann, Eszter Doma, Michaela Prchal-Murphy, Iris Z Uras, Alexander Höllein, Donna S Neuberg, Benjamin L Ebert, Anna Ringler, Andre C Mueller, Joanna I Loizou, Philip W Hinds, Claus Vogl, Gerwin Heller, Stefan Kubicek, Johannes Zuber, Marcos Malumbres, Matthias Farlik, Andreas Villunger, Karoline Kollmann, Veronika Sexl
CDK6 Antagonizes p53-Induced Responses during Tumorigenesis. Cancer discovery 8 (7) (2018)
Bettina Wingelhofer, Barbara Maurer, Elizabeth C Heyes, Abbarna A Cumaraswamy, Angelika Berger-Becvar, Elvin D de Araujo, Anna Orlova, Patricia Freund, Frank Ruge, Jisung Park, Gary Tin, Siawash Ahmar, Charles-Hugues Lardeau, Irina Sadovnik, Dávid Bajusz, György Miklós Keserű, Florian Grebien, Stefan Kubicek, Peter Valent, Patrick T Gunning, Richard H Moriggl
Pharmacologic inhibition of STAT5 in acute myeloid leukemia. Leukemia 32 (5) (2018)
Sri Teja Mullapudi, Christian Sm Helker, Giulia Lm Boezio, Hans-Martin Maischein, Anna M Sokol, Stefan Guenther, Hiroki Matsuda, Stefan Kubicek, Johannes Graumann, Yu Hsuan Carol Yang, Didier Y R Stainier
Screening for insulin-independent pathways that modulate glucose homeostasis identifies androgen receptor antagonists. eLife 7 (2018)
Gregory I Vladimer, Berend Snijder, Nikolaus Krall, Johannes W Bigenzahn, Kilian V M Huber, Charles-Hugues Lardeau, Kumar Sanjiv, Anna Ringler, Ulrika Warpman Berglund, Monika Sabler, Oscar Lopez de la Fuente, Paul Knöbl, Stefan Kubicek, Thomas Helleday, Ulrich Jäger, Giulio Superti-Furga
Global survey of the immunomodulatory potential of common drugs. Nature chemical biology 13 (6) (2017)
Bernd Boidol, Christoph Kornauth, Emiel van der Kouwe, Nicole Prutsch, Lukas Kazianka, Sinan Gültekin, Gregor Hoermann, Marius E Mayerhoefer, Georg Hopfinger, Alexander Hauswirth, Michael Panny, Marie-Bernadette Aretin, Bernadette Hilgarth, Wolfgang R Sperr, Peter Valent, Ingrid Simonitsch-Klupp, Richard Moriggl, Olaf Merkel, Lukas Kenner, Ulrich Jäger, Stefan Kubicek, Philipp Bernhard Staber
First-in-human response of BCL-2 inhibitor venetoclax in T-cell prolymphocytic leukemia. Blood 130 (23) (2017)
Marco P Licciardello, Anna Ringler, Patrick Markt, Freya Klepsch, Charles-Hugues Lardeau, Sara Sdelci, Erika Schirghuber, André C Müller, Michael Caldera, Anja Wagner, Rebecca Herzog, Thomas Penz, Michael Schuster, Bernd Boidol, Gerhard Dürnberger, Yasin Folkvaljon, Pär Stattin, Vladimir Ivanov, Jacques Colinge, Christoph Bock, Klaus Kratochwill, J Formula See Text Rg Menche, Keiryn L Bennett, Stefan Kubicek
A combinatorial screen of the CLOUD uncovers a synergy targeting the androgen receptor. Nature chemical biology 13 (7) (2017)
Rui Martins, Julia Maier, Anna-Dorothea Gorki, Kilian V M Huber, Omar Sharif, Philipp Starkl, Simona Saluzzo, Federica Quattrone, Riem Gawish, Karin Lakovits, Michael C Aichinger, Branka Radic-Sarikas, Charles-Hugues Lardeau, Anastasiya Hladik, Ana Korosec, Markus Brown, Kari Vaahtomeri, Michelle Duggan, Dontscho Kerjaschki, Harald Esterbauer, Jacques Colinge, Stephanie C Eisenbarth, Thomas Decker, Keiryn L Bennett, Stefan Kubicek, Michael Sixt, Giulio Superti-Furga, Sylvia Knapp
Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions. Nature immunology 17 (12) (2016)
Olga A Guryanova, Kaitlyn Shank, Barbara Spitzer, Luisa Luciani, Richard P Koche, Francine E Garrett-Bakelman, Chezi Ganzel, Benjamin H Durham, Abhinita Mohanty, Gregor Hoermann, Sharon A Rivera, Alan G Chramiec, Elodie Pronier, Lennart Bastian, Matthew D Keller, Daniel Tovbin, Evangelia Loizou, Abby R Weinstein, Adriana Rodriguez Gonzalez, Yen K Lieu, Jacob M Rowe, Friederike Pastore, Anna Sophia McKenney, Andrei V Krivtsov, Wolfgang R Sperr, Justin R Cross, Christopher E Mason, Martin S Tallman, Maria E Arcila, Omar Abdel-Wahab, Scott A Armstrong, Stefan Kubicek, Philipp B Staber, Mithat Gönen, Elisabeth M Paietta, Ari M Melnick, Stephen D Nimer, Siddhartha Mukherjee, Ross L Levine
DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling. Nature medicine 22 (12) (2016)
Sara Sdelci, Charles-Hugues Lardeau, Cynthia Tallant, Freya Klepsch, Björn Klaiber, James Bennett, Philipp Rathert, Michael Schuster, Thomas Penz, Oleg Fedorov, Giulio Superti-Furga, Christoph Bock, Johannes Zuber, Kilian V M Huber, Stefan Knapp, Susanne Müller, Stefan Kubicek
Mapping the chemical chromatin reactivation landscape identifies BRD4-TAF1 cross-talk. Nature chemical biology 12 (7) (2016)

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Stefan Kubicek