Kelly D Moynihan

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 20

Top Venues

Cancer discovery

Nature communications

Science translational medicine

Science immunology

Third Rock Ventures LLC

Massachusetts Institute of Technology (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Third Rock Ventures LLC Sep 04 2017

United States

Associate

Education History

Massachusetts Institute of Technology Sep 01 2012 - Aug 10 2017

United States

PHD :: Biological Engineering

University of Texas at Austin Sep 01 2008 - Jun 01 2012

United States

BSC :: Biomedical Engineering

Publications

Kelly D Moynihan, Manu P Kumar, Hussein Sultan, Danielle C Pappas, Terrence Park, S Michael Chin, Paul Bessette, Ruth Y Lan, Henry C Nguyen, Nathan D Mathewson, Irene Ni, Wei Chen, Yonghee Lee, Sindy Liao-Chan, Jessie Chen, Ton N M Schumacher, Robert D Schreiber, Yik A Yeung, Ivana M Djuretic
IL2 Targeted to CD8+ T Cells Promotes Robust Effector T-cell Responses and Potent Antitumor Immunity. Cancer discovery 14 (7) (2024)
Kelly D Moynihan, Manu P Kumar, Hussein Sultan, Danielle C Pappas, Terrence Park, S Michael Chin, Paul Bessette, Ruth Y Lan, Henry C Nguyen, Nathan D Mathewson, Irene Ni, Wei Chen, Yonghee Lee, Sindy Liao-Chan, Jessie Chen, Ton N M Schumacher, Robert D Schreiber, Yik A Yeung, Ivana M Djuretic
IL-2 targeted to CD8+ T cells promotes robust effector T cell responses and potent antitumor immunity. Cancer discovery (2024)
Paulien Kaptein, Nadine Slingerland, Christina Metoikidou, Felix Prinz, Simone Brokamp, Mercedes Machuca-Ostos, Guido de Roo, Ton N M Schumacher, Yik A Yeung, Kelly D Moynihan, Ivana M Djuretic, Daniela S Thommen
CD8-Targeted IL2 Unleashes Tumor-Specific Immunity in Human Cancer Tissue by Reviving the Dysfunctional T-cell Pool. Cancer discovery 14 (7) (2024)
Kelly D Moynihan, Manu P Kumar, Hussein Sultan, Danielle C Pappas, Terrence Park, S Michael Chin, Paul Bessette, Ruth Y Lan, Henry C Nguyen, Nathan D Mathewson, Irene Ni, Wei Chen, Yonghee Lee, Sindy Liao-Chan, Jessie Chen, Ton N M Schumacher, Robert D Schreiber, Yik A Yeung, Ivana M Djuretic
IL2 Targeted to CD8+ T Cells Promotes Robust Effector T-cell Responses and Potent Antitumor Immunity. Cancer discovery 14 (7) (2024)
Paulien Kaptein, Nadine Slingerland, Christina Metoikidou, Felix Prinz, Simone Brokamp, Mercedes Machuca-Ostos, Guido de Roo, Ton N M Schumacher, Yik A Yeung, Kelly D Moynihan, Ivana M Djuretic, Daniela S Thommen
CD8-Targeted IL2 Unleashes Tumor-Specific Immunity in Human Cancer Tissue by Reviving the Dysfunctional T-cell Pool. Cancer discovery 14 (7) (2024)
Francesco Andreata, Kelly D Moynihan, Valeria Fumagalli, Pietro Di Lucia, Danielle C Pappas, Keigo Kawashima, Irene Ni, Paul H Bessette, Chiara Perucchini, Elisa Bono, Leonardo Giustini, Henry C Nguyen, S Michael Chin, Yik Andy Yeung, Craig S Gibbs, Ivana Djuretic, Matteo Iannacone
CD8 cis-targeted IL-2 drives potent antiviral activity against hepatitis B virus. Science translational medicine 16 (729) (2024)
Paulien Kaptein, Nadine Slingerland, Christina Metoikidou, Felix Prinz, Simone Brokamp, Mercedes Machuca-Ostos, Guido de Roo, Ton N M Schumacher, Yik A Yeung, Kelly D Moynihan, Ivana M Djuretic, Daniela S Thommen
CD8-targeted IL2 unleashes tumor-specific immunity in human cancer tissue by reviving the dysfunctional T cell pool. Cancer discovery (2024)
Paulien Kaptein, Nadine Slingerland, Christina Metoikidou, Felix Prinz, Simone Brokamp, Mercedes Machuca-Ostos, Guido de Roo, Ton N M Schumacher, Yik A Yeung, Kelly D Moynihan, Ivana M Djuretic, Daniela S Thommen
CD8-Targeted IL2 Unleashes Tumor-Specific Immunity in Human Cancer Tissue by Reviving the Dysfunctional T-cell Pool. Cancer discovery 14 (7) (2024)
Kelly D Moynihan, Manu P Kumar, Hussein Sultan, Danielle C Pappas, Terrence Park, S Michael Chin, Paul Bessette, Ruth Y Lan, Henry C Nguyen, Nathan D Mathewson, Irene Ni, Wei Chen, Yonghee Lee, Sindy Liao-Chan, Jessie Chen, Ton N M Schumacher, Robert D Schreiber, Yik A Yeung, Ivana M Djuretic
IL2 Targeted to CD8+ T Cells Promotes Robust Effector T-cell Responses and Potent Antitumor Immunity. Cancer discovery 14 (7) (2024)
Paulien Kaptein, Nadine Slingerland, Christina Metoikidou, Felix Prinz, Simone Brokamp, Mercedes Machuca-Ostos, Guido de Roo, Ton N M Schumacher, Yik A Yeung, Kelly D Moynihan, Ivana M Djuretic, Daniela S Thommen
CD8-Targeted IL2 Unleashes Tumor-Specific Immunity in Human Cancer Tissue by Reviving the Dysfunctional T-cell Pool. Cancer discovery 14 (7) (2024)
Francesco Andreata, Kelly D Moynihan, Valeria Fumagalli, Pietro Di Lucia, Danielle C Pappas, Keigo Kawashima, Irene Ni, Paul H Bessette, Chiara Perucchini, Elisa Bono, Leonardo Giustini, Henry C Nguyen, S Michael Chin, Yik Andy Yeung, Craig S Gibbs, Ivana Djuretic, Matteo Iannacone
CD8 cis-targeted IL-2 drives potent antiviral activity against hepatitis B virus. Science translational medicine 16 (729) (2024)
Kelly D Moynihan, Manu P Kumar, Hussein Sultan, Danielle C Pappas, Terrence Park, S Michael Chin, Paul Bessette, Ruth Y Lan, Henry C Nguyen, Nathan D Mathewson, Irene Ni, Wei Chen, Yonghee Lee, Sindy Liao-Chan, Jessie Chen, Ton N M Schumacher, Robert D Schreiber, Yik A Yeung, Ivana M Djuretic
IL2 Targeted to CD8+ T Cells Promotes Robust Effector T-cell Responses and Potent Antitumor Immunity. Cancer discovery 14 (7) (2024)
Zachariah P Tritz, Katayoun Ayasoufi, Delaney M Wolf, Carley A Owens, Courtney S Malo, Benjamin T Himes, Cori E Fain, Emma N Goddery, Lila T Witt, Fang Jin, Michael J Hansen, Ian F Parney, Chensu Wang, Kelly D Moynihan, Darrell J Irvine, Karl Dane Wittrup, Rosa M Diaz Marcano, Richard G Vile, Aaron J Johnson
Anti-PD-1 and extended half-life-IL-2 synergize for treatment of murine glioblastoma independent of host MHC Class I expression. Cancer immunology research (2023)
Lawrence P Andrews, Ashwin S Somasundaram, Jessica M Moskovitz, Andrea L Szymczak-Workman, Chang Liu, Anthony R Cillo, Huang Lin, Daniel P Normolle, Kelly D Moynihan, Ichiro Taniuchi, Darrell J Irvine, Joanne M Jeter, Evan J Lipson, Robert L Ferris, Tullia C Bruno, Creg J Workman, Dario A A Vignali
Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding. Science immunology 5 (49) (2022)
Kavya Rakhra, Wuhbet Abraham, Chensu Wang, Kelly D Moynihan, Na Li, Nathan Donahue, Alexis D Baldeon, Darrell J Irvine
Exploiting albumin as a mucosal vaccine chaperone for robust generation of lung-resident memory T cells. Science immunology 6 (57) (2022)
Coralie M Backlund, Rebecca L Holden, Kelly D Moynihan, Daniel Garafola, Charlotte E Farquhar, Naveen K Mehta, Laura Maiorino, Sydney Pham, J Bryan Iorgulescu, David A Reardon, Catherine J Wu, Bradley L Pentelute, Darrell J Irvine
Cell-penetrating peptides enhance peptide vaccine accumulation and persistence in lymph nodes to drive immunogenicity. Proceedings of the National Academy of Sciences of the United States of America 119 (32) (2022)
Byong H Kang, Noor Momin, Kelly D Moynihan, Murillo Silva, Yingzhong Li, Darrell J Irvine, Karl Dane Wittrup
Immunotherapy-induced antibodies to endogenous retroviral envelope glycoprotein confer tumor protection in mice. PloS one 16 (4) (2021)
Yu-Sang Sabrina Yang, Prabhani U Atukorale, Kelly D Moynihan, Ahmet Bekdemir, Kavya Rakhra, Li Tang, Francesco Stellacci, Darrell J Irvine
High-throughput quantitation of inorganic nanoparticle biodistribution at the single-cell level using mass cytometry. Nature communications 8 (2017)
Kristin L Griffiths, Mushtaq Ahmed, Shibali Das, Radha Gopal, William Horne, Terry D Connell, Kelly D Moynihan, Jay K Kolls, Darrell J Irvine, Maxim N Artyomov, Javier Rangel-Moreno, Shabaana A Khader
Targeting dendritic cells to accelerate T-cell activation overcomes a bottleneck in tuberculosis vaccine efficacy. Nature communications 7 (2016)
Kelly D Moynihan, Cary F Opel, Gregory Lee Szeto, Alice Tzeng, Eric F Zhu, Jesse M Engreitz, Robert T Williams, Kavya Rakhra, Michael H Zhang, Adrienne M Rothschilds, Sudha Kumari, Ryan L Kelly, Byron H Kwan, Wuhbet Abraham, Kevin Hu, Naveen K Mehta, Monique J Kauke, Heikyung Suh, Jennifer R Cochran, Douglas A Lauffenburger, K Dane Wittrup, Darrell J Irvine
Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses. Nature medicine 22 (12) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Kelly D Moynihan