Dario A A Vignali (Dario Vignali)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 57

Top Topics

Squamous Cell Carcinoma

Regulatory T Cells

Top Venues

Journal of immunology (Baltimore, Md. : 1950)

Nature communications

Nature immunology

This page only lists publications with an associated author ORCID identifier.

Publications

Paul M Zdinak, Nishtha Trivedi, Stephanie Grebinoski, Jessica Torrey, Eduardo Zarate Martinez, Salome Martinez, Louise Hicks, Rashi Ranjan, Venkata Krishna Kanth Makani, Mary Melissa Roland, Lyubov Kublo, Sanya Arshad, Mark S Anderson, Dario A A Vignali, Alok V Joglekar
De novo identification of CD4 + T cell epitopes. Nature methods (2024)
Xiaobo Mao, Hao Gu, Donghoon Kim, Yasuyoshi Kimura, Ning Wang, Enquan Xu, Ramhari Kumbhar, Xiaotian Ming, Haibo Wang, Chan Chen, Shengnan Zhang, Chunyu Jia, Yuqing Liu, Hetao Bian, Senthilkumar S Karuppagounder, Fatih Akkentli, Qi Chen, Longgang Jia, Heehong Hwang, Su Hyun Lee, Xiyu Ke, Michael Chang, Amanda Li, Jun Yang, Cyrus Rastegar, Manjari Sriparna, Preston Ge, Saurav Brahmachari, Sangjune Kim, Shu Zhang, Yasushi Shimoda, Martina Saar, Haiqing Liu, Sin Ho Kweon, Mingyao Ying, Creg J Workman, Dario A A Vignali, Ulrike C Muller, Cong Liu, Han Seok Ko, Valina L Dawson, Ted M Dawson
Author Correction: Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein. Nature communications 15 (1) (2024)
Kieran Adam, Zhanna Lipatova, Maria Abdul Ghafoor Raja, Arjun K Mishra, Roy A Mariuzza, Creg J Workman, Dario A A Vignali
Cutting Edge: LAG3 Dimerization Is Required for TCR/CD3 Interaction and Inhibition of Antitumor Immunity. Journal of immunology (Baltimore, Md. : 1950) 213 (1) (2024)
Stephanie Grebinoski, Gwenyth Pieklo, Qianxia Zhang, Anabelle Visperas, Jian Cui, Jordana Goulet, Hanxi Xiao, Erin A Brunazzi, Carly Cardello, Andrés A Herrada, Jishnu Das, Creg J Workman, Dario A A Vignali
Regulatory T Cell Insufficiency in Autoimmune Diabetes Is Driven by Selective Loss of Neuropilin-1 on Intraislet Regulatory T Cells. Journal of immunology (Baltimore, Md. : 1950) (2024)
Paul M Zdinak, Nishtha Trivedi, Stephanie Grebinoski, Jessica Torrey, Eduardo Zarate Martinez, Salome Martinez, Louise Hicks, Rashi Ranjan, Venkata Krishna Kanth Makani, Mary Melissa Roland, Lyubov Kublo, Sanya Arshad, Mark S Anderson, Dario A A Vignali, Alok V Joglekar
De novo identification of CD4 + T cell epitopes. Nature methods 21 (5) (2024)
Kieran Adam, Zhanna Lipatova, Maria Abdul Ghafoor Raja, Arjun K Mishra, Roy A Mariuzza, Creg J Workman, Dario A A Vignali
Cutting Edge: LAG3 Dimerization Is Required for TCR/CD3 Interaction and Inhibition of Antitumor Immunity. Journal of immunology (Baltimore, Md. : 1950) (2024)
Xiaobo Mao, Hao Gu, Donghoon Kim, Yasuyoshi Kimura, Ning Wang, Enquan Xu, Ramhari Kumbhar, Xiaotian Ming, Haibo Wang, Chan Chen, Shengnan Zhang, Chunyu Jia, Yuqing Liu, Hetao Bian, Senthilkumar S Karuppagounder, Fatih Akkentli, Qi Chen, Longgang Jia, Heehong Hwang, Su Hyun Lee, Xiyu Ke, Michael Chang, Amanda Li, Jun Yang, Cyrus Rastegar, Manjari Sriparna, Preston Ge, Saurav Brahmachari, Sangjune Kim, Shu Zhang, Yasushi Shimoda, Martina Saar, Haiqing Liu, Sin Ho Kweon, Mingyao Ying, Creg J Workman, Dario A A Vignali, Ulrike C Muller, Cong Liu, Han Seok Ko, Valina L Dawson, Ted M Dawson
Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein. Nature communications 15 (1) (2024)
Paul M Zdinak, Nishtha Trivedi, Stephanie Grebinoski, Jessica Torrey, Eduardo Zarate Martinez, Salome Martinez, Louise Hicks, Rashi Ranjan, Venkata Krishna Kanth Makani, Mary Melissa Roland, Lyubov Kublo, Sanya Arshad, Mark S Anderson, Dario A A Vignali, Alok V Joglekar
De novo identification of CD4 + T cell epitopes. Nature methods 21 (5) (2024)
Xiaobo Mao, Hao Gu, Donghoon Kim, Yasuyoshi Kimura, Ning Wang, Enquan Xu, Ramhari Kumbhar, Xiaotian Ming, Haibo Wang, Chan Chen, Shengnan Zhang, Chunyu Jia, Yuqing Liu, Hetao Bian, Senthilkumar S Karuppagounder, Fatih Akkentli, Qi Chen, Longgang Jia, Heehong Hwang, Su Hyun Lee, Xiyu Ke, Michael Chang, Amanda Li, Jun Yang, Cyrus Rastegar, Manjari Sriparna, Preston Ge, Saurav Brahmachari, Sangjune Kim, Shu Zhang, Yasushi Shimoda, Martina Saar, Haiqing Liu, Sin Ho Kweon, Mingyao Ying, Creg J Workman, Dario A A Vignali, Ulrike C Muller, Cong Liu, Han Seok Ko, Valina L Dawson, Ted M Dawson
Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein. Nature communications 15 (1) (2024)
Kieran Adam, Zhanna Lipatova, Maria Abdul Ghafoor Raja, Arjun K Mishra, Roy A Mariuzza, Creg J Workman, Dario A A Vignali
Cutting Edge: LAG3 Dimerization Is Required for TCR/CD3 Interaction and Inhibition of Antitumor Immunity. Journal of immunology (Baltimore, Md. : 1950) 213 (1) (2024)
Kieran Adam, Zhanna Lipatova, Maria Abdul Ghafoor Raja, Arjun K Mishra, Roy A Mariuzza, Creg J Workman, Dario A A Vignali
Cutting Edge: LAG3 Dimerization Is Required for TCR/CD3 Interaction and Inhibition of Antitumor Immunity. Journal of immunology (Baltimore, Md. : 1950) 213 (1) (2024)
Xiaobo Mao, Hao Gu, Donghoon Kim, Yasuyoshi Kimura, Ning Wang, Enquan Xu, Ramhari Kumbhar, Xiaotian Ming, Haibo Wang, Chan Chen, Shengnan Zhang, Chunyu Jia, Yuqing Liu, Hetao Bian, Senthilkumar S Karuppagounder, Fatih Akkentli, Qi Chen, Longgang Jia, Heehong Hwang, Su Hyun Lee, Xiyu Ke, Michael Chang, Amanda Li, Jun Yang, Cyrus Rastegar, Manjari Sriparna, Preston Ge, Saurav Brahmachari, Sangjune Kim, Shu Zhang, Yasushi Shimoda, Martina Saar, Haiqing Liu, Sin Ho Kweon, Mingyao Ying, Creg J Workman, Dario A A Vignali, Ulrike C Muller, Cong Liu, Han Seok Ko, Valina L Dawson, Ted M Dawson
Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein. Nature communications 15 (1) (2024)
Kieran Adam, Zhanna Lipatova, Maria Abdul Ghafoor Raja, Arjun K Mishra, Roy A Mariuzza, Creg J Workman, Dario A A Vignali
Cutting Edge: LAG3 Dimerization Is Required for TCR/CD3 Interaction and Inhibition of Antitumor Immunity. Journal of immunology (Baltimore, Md. : 1950) 213 (1) (2024)
Xiaobo Mao, Hao Gu, Donghoon Kim, Yasuyoshi Kimura, Ning Wang, Enquan Xu, Ramhari Kumbhar, Xiaotian Ming, Haibo Wang, Chan Chen, Shengnan Zhang, Chunyu Jia, Yuqing Liu, Hetao Bian, Senthilkumar S Karuppagounder, Fatih Akkentli, Qi Chen, Longgang Jia, Heehong Hwang, Su Hyun Lee, Xiyu Ke, Michael Chang, Amanda Li, Jun Yang, Cyrus Rastegar, Manjari Sriparna, Preston Ge, Saurav Brahmachari, Sangjune Kim, Shu Zhang, Yasushi Shimoda, Martina Saar, Haiqing Liu, Sin Ho Kweon, Mingyao Ying, Creg J Workman, Dario A A Vignali, Ulrike C Muller, Cong Liu, Han Seok Ko, Valina L Dawson, Ted M Dawson
Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein. Nature communications 15 (1) (2024)
Paul M Zdinak, Nishtha Trivedi, Stephanie Grebinoski, Jessica Torrey, Eduardo Zarate Martinez, Salome Martinez, Louise Hicks, Rashi Ranjan, Venkata Krishna Kanth Makani, Mary Melissa Roland, Lyubov Kublo, Sanya Arshad, Mark S Anderson, Dario A A Vignali, Alok V Joglekar
De novo identification of CD4 + T cell epitopes. Nature methods 21 (5) (2024)
Ellen N Scott, Cheng Ye, Hiroshi Yano, Zhanna Lipatova, Erin Brunazzi, Kate M Vignali, Creg J Workman, Dario A A Vignali
Ebi3 Binding to IFN-γ and IL-10 Limits Their Function. Journal of immunology (Baltimore, Md. : 1950) (2024)
Paul M Zdinak, Nishtha Trivedi, Stephanie Grebinoski, Jessica Torrey, Eduardo Zarate Martinez, Salome Martinez, Louise Hicks, Rashi Ranjan, Venkata Krishna Kanth Makani, Mary Melissa Roland, Lyubov Kublo, Sanya Arshad, Mark S Anderson, Dario A A Vignali, Alok V Joglekar
De novo identification of CD4 + T cell epitopes. Nature methods 21 (5) (2024)
Paul M Zdinak, Nishtha Trivedi, Stephanie Grebinoski, Jessica Torrey, Eduardo Zarate Martinez, Salome Martinez, Louise Hicks, Rashi Ranjan, Venkata Krishna Kanth Makani, Mary Melissa Roland, Lyubov Kublo, Sanya Arshad, Mark S Anderson, Dario A A Vignali, Alok V Joglekar
De novo identification of CD4 + T cell epitopes. Nature methods 21 (5) (2024)
Kieran Adam, Zhanna Lipatova, Maria Abdul Ghafoor Raja, Arjun K Mishra, Roy A Mariuzza, Creg J Workman, Dario A A Vignali
Cutting Edge: LAG3 Dimerization Is Required for TCR/CD3 Interaction and Inhibition of Antitumor Immunity. Journal of immunology (Baltimore, Md. : 1950) 213 (1) (2024)
Kieran Adam, Zhanna Lipatova, Maria Abdul Ghafoor Raja, Arjun K Mishra, Roy A Mariuzza, Creg J Workman, Dario A A Vignali
Cutting Edge: LAG3 Dimerization Is Required for TCR/CD3 Interaction and Inhibition of Antitumor Immunity. Journal of immunology (Baltimore, Md. : 1950) (2024)
Xiaobo Mao, Hao Gu, Donghoon Kim, Yasuyoshi Kimura, Ning Wang, Enquan Xu, Ramhari Kumbhar, Xiaotian Ming, Haibo Wang, Chan Chen, Shengnan Zhang, Chunyu Jia, Yuqing Liu, Hetao Bian, Senthilkumar S Karuppagounder, Fatih Akkentli, Qi Chen, Longgang Jia, Heehong Hwang, Su Hyun Lee, Xiyu Ke, Michael Chang, Amanda Li, Jun Yang, Cyrus Rastegar, Manjari Sriparna, Preston Ge, Saurav Brahmachari, Sangjune Kim, Shu Zhang, Yasushi Shimoda, Martina Saar, Haiqing Liu, Sin Ho Kweon, Mingyao Ying, Creg J Workman, Dario A A Vignali, Ulrike C Muller, Cong Liu, Han Seok Ko, Valina L Dawson, Ted M Dawson
Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein. Nature communications 15 (1) (2024)
Xiaobo Mao, Hao Gu, Donghoon Kim, Yasuyoshi Kimura, Ning Wang, Enquan Xu, Ramhari Kumbhar, Xiaotian Ming, Haibo Wang, Chan Chen, Shengnan Zhang, Chunyu Jia, Yuqing Liu, Hetao Bian, Senthilkumar S Karuppagounder, Fatih Akkentli, Qi Chen, Longgang Jia, Heehong Hwang, Su Hyun Lee, Xiyu Ke, Michael Chang, Amanda Li, Jun Yang, Cyrus Rastegar, Manjari Sriparna, Preston Ge, Saurav Brahmachari, Sangjune Kim, Shu Zhang, Yasushi Shimoda, Martina Saar, Haiqing Liu, Sin Ho Kweon, Mingyao Ying, Creg J Workman, Dario A A Vignali, Ulrike C Muller, Cong Liu, Han Seok Ko, Valina L Dawson, Ted M Dawson
Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein. Nature communications 15 (1) (2024)
Xiaobo Mao, Hao Gu, Donghoon Kim, Yasuyoshi Kimura, Ning Wang, Enquan Xu, Ramhari Kumbhar, Xiaotian Ming, Haibo Wang, Chan Chen, Shengnan Zhang, Chunyu Jia, Yuqing Liu, Hetao Bian, Senthilkumar S Karuppagounder, Fatih Akkentli, Qi Chen, Longgang Jia, Heehong Hwang, Su Hyun Lee, Xiyu Ke, Michael Chang, Amanda Li, Jun Yang, Cyrus Rastegar, Manjari Sriparna, Preston Ge, Saurav Brahmachari, Sangjune Kim, Shu Zhang, Yasushi Shimoda, Martina Saar, Haiqing Liu, Sin Ho Kweon, Mingyao Ying, Creg J Workman, Dario A A Vignali, Ulrike C Muller, Cong Liu, Han Seok Ko, Valina L Dawson, Ted M Dawson
Author Correction: Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein. Nature communications 15 (1) (2024)
Victoria H Wu, Bryan S Yung, Farhoud Faraji, Robert Saddawi-Konefka, Zhiyong Wang, Alexander T Wenzel, Miranda J Song, Meghana S Pagadala, Lauren M Clubb, Joshua Chiou, Sanju Sinha, Marin Matic, Francesco Raimondi, Thomas S Hoang, Rebecca Berdeaux, Dario A A Vignali, Ramiro Iglesias-Bartolome, Hannah Carter, Eytan Ruppin, Jill P Mesirov, Jorge Silvio Gutkind
The GPCR-Gα s -PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure. Nature immunology (2023)
Tamara Cruz, Paula A Agudelo Garcia, Julián A Chamucero-Millares, Anna Bondonese, Nilay Mitash, John Charles Sembrat, Tracy Tabib, Wenping Zhang, Nouraie Seyed, Victor Peters, Sean Stacey, Dario A A Vignali, Ana L Mora, Robert Lafyatis, Mauricio Rojas
End-Stage Idiopathic Pulmonary Fibrosis Lung Microenvironment Promotes Impaired NK Activity. Journal of immunology (Baltimore, Md. : 1950) (2023)
Sayali Onkar, Jian Cui, Jian Zou, Carly Cardello, Anthony R Cillo, Mostofa Rafid Uddin, April Sagan, Marion Joy, Hatice U Osmanbeyoglu, Katherine L Pogue-Geile, Priscilla F McAuliffe, Peter C Lucas, George C Tseng, Adrian V Lee, Tullia C Bruno, Steffi Oesterreich, Dario A A Vignali
Immune landscape in invasive ductal and lobular breast cancer reveals a divergent macrophage-driven microenvironment. Nature cancer (2023)
Feng Shan, Anthony R Cillo, Carly Cardello, Daniel Y Yuan, Sheryl R Kunning, Jian Cui, Caleb Lampenfeld, Asia M Williams, Alexandra P McDonough, Arjun Pennathur, James D Luketich, Joanne M Jeter, Matthew J Ferris, Tullia C Bruno, Creg J Workman, Panayiotis V Benos, Dario A A Vignali
Integrated BATF transcriptional network regulates suppressive intratumoral regulatory T cells. Science immunology 8 (87) (2023)
Sayali Onkar, Jian Cui, Jian Zou, Carly Cardello, Anthony R Cillo, Mostofa Rafid Uddin, April Sagan, Marion Joy, Hatice U Osmanbeyoglu, Katherine L Pogue-Geile, Priscilla F McAuliffe, Peter C Lucas, George C Tseng, Adrian V Lee, Tullia C Bruno, Steffi Oesterreich, Dario A A Vignali
Immune landscape in invasive ductal and lobular breast cancer reveals a divergent macrophage-driven microenvironment. Nature cancer (2023)
Vaishali Aggarwal, Creg J Workman, Dario A A Vignali
LAG-3 as the third checkpoint inhibitor. Nature immunology (2023)
Sayali Onkar, Jian Cui, Jian Zou, Carly Cardello, Anthony R Cillo, Mostofa Rafid Uddin, April Sagan, Marion Joy, Hatice U Osmanbeyoglu, Katherine L Pogue-Geile, Priscilla F McAuliffe, Peter C Lucas, George C Tseng, Adrian V Lee, Tullia C Bruno, Steffi Oesterreich, Dario A A Vignali
Publisher Correction: Immune landscape in invasive ductal and lobular breast cancer reveals a divergent macrophage-driven microenvironment. Nature cancer (2023)
Angela M Gocher-Demske, Jian Cui, Andrea L Szymczak-Workman, Kate M Vignali, Julianna N Latini, Gwen P Pieklo, Jesse C Kimball, Lyndsay Avery, Ellyse M Cipolla, Brydie R Huckestein, Lee Hedden, Marlies Meisel, John F Alcorn, Lawrence P Kane, Creg J Workman, Dario A A Vignali
IFNγ-induction of T H 1-like regulatory T cells controls antiviral responses. Nature immunology (2023)
Stephanie Grebinoski, Qianxia Zhang, Anthony R Cillo, Sasikanth Manne, Hanxi Xiao, Erin A Brunazzi, Tracy Tabib, Carly Cardello, Christine G Lian, George F Murphy, Robert Lafyatis, E John Wherry, Jishnu Das, Creg J Workman, Dario A A Vignali
Autoreactive CD8 + T cells are restrained by an exhaustion-like program that is maintained by LAG3. Nature immunology 23 (6) (2022)
Stephanie Grebinoski, Angela M Gocher-Demske, Dario A A Vignali
Catch and release: freeing up PD-L1 ameliorates autoimmunity. Nature immunology 23 (3) (2022)
Zheqi Li, Olivia McGinn, Yang Wu, Amir Bahreini, Nolan M Priedigkeit, Kai Ding, Sayali Onkar, Caleb Lampenfeld, Carol A Sartorius, Lori Miller, Margaret Rosenzweig, Ofir Cohen, Nikhil Wagle, Jennifer K Richer, William J Muller, Lakjaya Buluwela, Simak Ali, Tullia C Bruno, Dario A A Vignali, Yusi Fang, Li Zhu, George C Tseng, Jason Gertz, Jennifer M Atkinson, Adrian V Lee, Steffi Oesterreich
ESR1 mutant breast cancers show elevated basal cytokeratins and immune activation. Nature communications 13 (1) (2022)
Lawrence P Andrews, Ashwin S Somasundaram, Jessica M Moskovitz, Andrea L Szymczak-Workman, Chang Liu, Anthony R Cillo, Huang Lin, Daniel P Normolle, Kelly D Moynihan, Ichiro Taniuchi, Darrell J Irvine, Joanne M Jeter, Evan J Lipson, Robert L Ferris, Tullia C Bruno, Creg J Workman, Dario A A Vignali
Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding. Science immunology 5 (49) (2022)
Anthony R Cillo, Elina Mukherjee, Nathanael Glen Bailey, Sayali S Onkar, Jessica Daley, Cláudia M Salgado, Xiang Li, Dongyan Liu, Sarangarajan Ranganathan, Melissa A Burgess, John Charles Sembrat, Kurt R Weiss, Rebecca J Watters, Tullia C Bruno, Dario A A Vignali, Kelly M Bailey
Ewing Sarcoma and Osteosarcoma Have Distinct Immune Signatures and Intercellular Communication Networks. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (22) (2022)
Ashwin S Somasundaram, Anthony R Cillo, Caleb Lampenfeld, Creg J Workman, Sheryl R Kunning, Lauren Oliveri, Maria A Velez, Sonali C Joyce, Michael J Calderon, Rebekah Dadey, Dhivyaa Rajasundaram, Daniel P Normolle, Simon C Watkins, James G Herman, Joanne M Jeter, Evan J Lipson, Matthew J Ferris, Tullia C Bruno, Dario A A Vignali
Systemic Immune Dysfunction in Cancer Patients Driven by IL6 Induction of LAG3 in Peripheral CD8+ T Cells. Cancer immunology research 10 (7) (2022)
Lawrence P Andrews, Anthony R Cillo, Lilit Karapetyan, Joanne M Jeter, Creg J Workman, Dario A A Vignali
Molecular Pathways and Mechanisms of LAG3 in Cancer Therapy. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (23) (2022)
Jonathan B Johnnidis, Yuki Muroyama, Shin Foong Ngiow, Zeyu Chen, Sasikanth Manne, Zhangying Cai, Shufei Song, Jesse M Platt, Jason M Schenkel, Mohamed S Abdel Hakeem, Jean-Christophe Beltra, Allison R Greenplate, Mohammed-Alkhatim A Ali, Kito Nzingha, Josephine R Giles, Christelle Harly, John Attanasio, Kristen E Pauken, Bertram Bengsch, Michael A Paley, Vesselin T Tomov, Makoto Kurachi, Dario A A Vignali, Arlene H Sharpe, Steven L Reiner, Avinash Bhandoola, F Bradley Johnson, E John Wherry
Inhibitory signaling sustains a distinct early memory CD8+ T cell precursor that is resistant to DNA damage. Science immunology 6 (55) (2022)
Pragati Agnihotri, Arjun K Mishra, Priyanka Agarwal, Kate M Vignali, Creg J Workman, Dario A A Vignali, Roy A Mariuzza
Epitope Mapping of Therapeutic Antibodies Targeting Human LAG3. Journal of immunology (Baltimore, Md. : 1950) 209 (8) (2022)
Clifford Guy, Diana M Mitrea, Po-Chien Chou, Jamshid Temirov, Kate M Vignali, Xueyan Liu, M-Marsel Mesulam, Richard W Kriwacki, Marcel P Bruchez, Simon C Watkins, Creg J Workman, Dario A A Vignali
LAG3 associates with TCR-CD3 complexes and suppresses signaling by driving co-receptor-Lck dissociation. Nature immunology 23 (5) (2022)
Robert L Ferris, Jessica Moskovitz, Sheryl Kunning, Ayana T Ruffin, Carly Reeder, James Ohr, William E Gooding, Seungwon Kim, Brian J Karlovits, Dario A A Vignali, Umamaheswar Duvvuri, Jonas T Johnson, Daniel Petro, Dwight E Heron, David A Clump, Tullia C Bruno, Julie E Bauman
Phase I Trial of Cetuximab, Radiotherapy, and Ipilimumab in Locally Advanced Head and Neck Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (7) (2022)
Rebekah E Dadey, Stephanie Grebinoski, Qianxia Zhang, Erin A Brunazzi, Amanda Burton, Creg J Workman, Dario A A Vignali
Regulatory T Cell-Derived TRAIL Is Not Required for Peripheral Tolerance. ImmunoHorizons 5 (1) (2021)
Christopher A Chuckran, Anthony R Cillo, Jessica M Moskovitz, Abigail Overacre-Delgoffe, Ashwin S Somasundaram, Feng Shan, Grant C Magnon, Sheryl R Kunning, Irina Abecassis, Amer H Zureikat, James D Luketich, Arjun Pennathur, John Charles Sembrat, Mauricio Rojas, Daniel T Merrick, Sarah E Taylor, Brian C Orr, Francesmary Modugno, Ronald J Buckanovich, Robert E Schoen, Seungwon Kim, Umamaheswar Duvvuri, Herbert J Zeh, Robert Edwards, Joanne M Jeter, Lan G Coffman, Robert L Ferris, Tullia C Bruno, Dario A A Vignali
Prevalence of intratumoral regulatory T cells expressing neuropilin-1 is associated with poorer outcomes in patients with cancer. Science translational medicine 13 (623) (2021)
Angela M Gocher, Creg J Workman, Dario A A Vignali
Interferon-γ: teammate or opponent in the tumour microenvironment? Nature reviews. Immunology (2021)
Sandra Cascio, Chelsea Chandler, Linan Zhang, Sarah Sinno, Bingsi Gao, Sayali S Onkar, Tullia C Bruno, Dario A A Vignali, Haider Mahdi, Hatice U Osmanbeyoglu, Anda M Vlad, Lan G Coffman, Ronald J Buckanovich
Cancer-associated MSC drive tumor immune exclusion and resistance to immunotherapy, which can be overcome by Hedgehog inhibition. Science advances 7 (46) (2021)
McLane J Watson, Paolo D A Vignali, Steven J Mullett, Abigail E Overacre-Delgoffe, Ronal M Peralta, Stephanie Grebinoski, Ashley V Menk, Natalie L Rittenhouse, Kristin DePeaux, Ryan D Whetstone, Dario A A Vignali, Timothy W Hand, Amanda C Poholek, Brett M Morrison, Jeffrey D Rothstein, Stacy G Wendell, Greg M Delgoffe
Metabolic support of tumour-infiltrating regulatory T cells by lactic acid. Nature 591 (7851) (2021)
Mélanie Gaignage, Catherine Uyttenhove, Lindsay L Jones, Christophe Bourdeaux, Paméla Chéou, Mohamed F Mandour, Jean-Paul Coutelier, Dario A A Vignali, Jacques Van Snick
Novel antibodies that selectively block mouse IL-12 enable the re-evaluation of the role of IL-12 in immune protection and pathology. European journal of immunology 51 (6) (2021)
Ayana T Ruffin, Anthony R Cillo, Tracy Tabib, Angen Liu, Sayali Onkar, Sheryl R Kunning, Caleb Lampenfeld, Huda I Atiya, Irina Abecassis, Cornelius H L Kürten, Zengbiao Qi, Ryan Soose, Umamaheswar Duvvuri, Seungwon Kim, Steffi Oesterreich, Robert Lafyatis, Lan G Coffman, Robert L Ferris, Dario A A Vignali, Tullia C Bruno
B cell signatures and tertiary lymphoid structures contribute to outcome in head and neck squamous cell carcinoma. Nature communications 12 (1) (2021)
Lucas D Faustino, Jason W Griffith, Rod A Rahimi, Keshav Nepal, Daniel L Hamilos, Josalyn L Cho, Benjamin D Medoff, James J Moon, Dario A A Vignali, Andrew D Luster
Interleukin-33 activates regulatory T cells to suppress innate γδ T cell responses in the lung. Nature immunology 21 (11) (2020)
Bhalchandra Mirlekar, Daniel Michaud, Samuel J Lee, Nancy P Kren, Cameron Harris, Kevin Greene, Emily C Goldman, Gaorav P Gupta, Ryan C Fields, William G Hawkins, David G DeNardo, Naim U Rashid, Jen Jen Yeh, Autumn J McRee, Benjamin G Vincent, Dario A A Vignali, Yuliya Pylayeva-Gupta
B cell-Derived IL35 Drives STAT3-Dependent CD8+ T-cell Exclusion in Pancreatic Cancer. Cancer immunology research 8 (3) (2020)
Chang Liu, Ashwin Somasundaram, Sasikanth Manne, Angela M Gocher, Andrea L Szymczak-Workman, Kate M Vignali, Ellen N Scott, Daniel P Normolle, E John Wherry, Evan J Lipson, Robert L Ferris, Tullia C Bruno, Creg J Workman, Dario A A Vignali
Neuropilin-1 is a T cell memory checkpoint limiting long-term antitumor immunity. Nature immunology 21 (9) (2020)
Hiroshi Yano, Lawrence P Andrews, Creg J Workman, Dario A A Vignali
Intratumoral regulatory T cells: markers, subsets and their impact on anti-tumor immunity. Immunology 157 (3) (2019)
Lawrence P Andrews, Hiroshi Yano, Dario A A Vignali
Inhibitory receptors and ligands beyond PD-1, PD-L1 and CTLA-4: breakthroughs or backups. Nature immunology 20 (11) (2019)
Zhe Sun, Li Chen, Hongyi Xin, Yale Jiang, Qianhui Huang, Anthony R Cillo, Tracy Tabib, Jay K Kolls, Tullia C Bruno, Robert Lafyatis, Dario A A Vignali, Kong Chen, Ying Ding, Ming Hu, Wei Chen
A Bayesian mixture model for clustering droplet-based single-cell transcriptomic data from population studies. Nature communications 10 (1) (2019)
Deepali V Sawant, Hiroshi Yano, Maria Chikina, Qianxia Zhang, Mengting Liao, Chang Liu, Derrick J Callahan, Zhe Sun, Tao Sun, Tracy Tabib, Arjun Pennathur, David B Corry, James D Luketich, Robert Lafyatis, Wei Chen, Amanda C Poholek, Tullia C Bruno, Creg J Workman, Dario A A Vignali
Adaptive plasticity of IL-10+ and IL-35+ Treg cells cooperatively promotes tumor T cell exhaustion. Nature immunology 20 (6) (2019)
Joseph R Podojil, Ming-Yi Chiang, Igal Ifergan, Ronald Copeland, Linda N Liu, Sebastien Maloveste, Solomon Langermann, David Liebenson, Roumen Balabanov, Hongbo Chi, Lieping Chen, Dario A A Vignali, Stephen D Miller
B7-H4 Modulates Regulatory CD4+ T Cell Induction and Function via Ligation of a Semaphorin 3a/Plexin A4/Neuropilin-1 Complex. Journal of immunology (Baltimore, Md. : 1950) 201 (3) (2018)