Darrell J Irvine

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 104

Top Venues

Science (New York, N.Y.)

ACS nano

Journal of immunology (Baltimore, Md. : 1950)

bioRxiv : the preprint server for biology

This page only lists publications with an associated author ORCID identifier.

Publications

Sachin H Bhagchandani, Leerang Yang, Jonathan H Lam, Laura Maiorino, Elana Ben-Akiva, Kristen A Rodrigues, Anna Romanov, Heikyung Suh, Aereas Aung, Shengwei Wu, Anika Wadhera, Arup K Chakraborty, Darrell J Irvine
Two-dose priming immunization amplifies humoral immunity by synchronizing vaccine delivery with the germinal center response. Science immunology 9 (99) (2024)
Yonger Xue, Yuebao Zhang, Yichen Zhong, Shi Du, Xucheng Hou, Wenqing Li, Haoyuan Li, Siyu Wang, Chang Wang, Jingyue Yan, Diana D Kang, Binbin Deng, David W McComb, Darrell J Irvine, Ron Weiss, Yizhou Dong
LNP-RNA-engineered adipose stem cells for accelerated diabetic wound healing. Nature communications 15 (1) (2024)
Aereas Aung, Darrell J Irvine
Modulating Antigen Availability in Lymphoid Organs to Shape the Humoral Immune Response to Vaccines. Journal of immunology (Baltimore, Md. : 1950) 212 (2) (2024)
Aereas Aung, Darrell J Irvine
Modulating Antigen Availability in Lymphoid Organs to Shape the Humoral Immune Response to Vaccines. Journal of immunology (Baltimore, Md. : 1950) 212 (2) (2024)
Yonger Xue, Yuebao Zhang, Yichen Zhong, Shi Du, Xucheng Hou, Wenqing Li, Haoyuan Li, Siyu Wang, Chang Wang, Jingyue Yan, Diana D Kang, Binbin Deng, David W McComb, Darrell J Irvine, Ron Weiss, Yizhou Dong
LNP-RNA-engineered adipose stem cells for accelerated diabetic wound healing. Nature communications 15 (1) (2024)
Yonger Xue, Yuebao Zhang, Yichen Zhong, Shi Du, Xucheng Hou, Wenqing Li, Haoyuan Li, Siyu Wang, Chang Wang, Jingyue Yan, Diana D Kang, Binbin Deng, David W McComb, Darrell J Irvine, Ron Weiss, Yizhou Dong
LNP-RNA-engineered adipose stem cells for accelerated diabetic wound healing. Nature communications 15 (1) (2024)
Aereas Aung, Darrell J Irvine
Modulating Antigen Availability in Lymphoid Organs to Shape the Humoral Immune Response to Vaccines. Journal of immunology (Baltimore, Md. : 1950) 212 (2) (2024)
Kewen Lei, Darrell J Irvine
A mobile home for T cells. Nature materials 23 (6) (2024)
Aereas Aung, Darrell J Irvine
Modulating Antigen Availability in Lymphoid Organs to Shape the Humoral Immune Response to Vaccines. Journal of immunology (Baltimore, Md. : 1950) 212 (2) (2024)
Ozgun Kocabiyik, Parastoo Amlashi, A Lina Vo, Heikyung Suh, Sergio A Rodriguez-Aponte, Neil C Dalvie, John Christopher Love, Raiees Andrabi, Darrell J Irvine
Vaccine targeting to mucosal lymphoid tissues promotes humoral immunity in the gastrointestinal tract. Science advances 10 (22) (2024)
Christopher A Cottrell, Payal P Pratap, Kimberly M Cirelli, Diane G Carnathan, Chiamaka A Enemuo, Aleksandar Antanasijevic, Gabriel Ozorowski, Leigh M Sewall, Hongmei Gao, Joel D Allen, Bartek Nogal, Murillo Silva, Jinal Bhiman, Matthias Pauthner, Darrell J Irvine, David Montefiori, Max Crispin, Dennis R Burton, Guido Silvestri, Shane Crotty, Andrew B Ward
Priming antibody responses to the fusion peptide in rhesus macaques. NPJ vaccines 9 (1) (2024)
Luciano Santollani, Laura Maiorino, Yiming J Zhang, Joseph R Palmeri, Jordan A Stinson, Lauren R Duhamel, Kashif Qureshi, Jack R Suggs, Owen T Porth, William Pinney, Riyam Al Msari, Agnes A Walsh, K Dane Wittrup, Darrell J Irvine
Local delivery of cell surface-targeted immunocytokines programs systemic antitumor immunity. Nature immunology (2024)
Valerie Lensch, Adele Gabba, Robert Hincapie, Sachin H Bhagchandani, Ankit Basak, Mohammad Murshid Alam, Darrell J Irvine, Alex K Shalek, Jeremiah A Johnson, Neal K Devaraj, Laura L Kiessling
Glycan-costumed virus-like particles promote type 1 anti-tumor immunity. bioRxiv : the preprint server for biology (2024)
Valerie Lensch, Adele Gabba, Robert Hincapie, Sachin H Bhagchandani, Ankit Basak, Mohammad Murshid Alam, Darrell J Irvine, Alex K Shalek, Jeremiah A Johnson, Neal K Devaraj, Laura L Kiessling
Glycan-costumed virus-like particles promote type 1 anti-tumor immunity. bioRxiv : the preprint server for biology (2024)
Valerie Lensch, Adele Gabba, Robert Hincapie, Sachin H Bhagchandani, Ankit Basak, Mohammad Murshid Alam, Darrell J Irvine, Alex K Shalek, Jeremiah A Johnson, Neal K Devaraj, Laura L Kiessling
Glycan-costumed virus-like particles promote type 1 anti-tumor immunity. bioRxiv : the preprint server for biology (2024)
Nicholas L Truex, Somesh Mohapatra, Mariane Melo, Jacob Rodriguez, Na Li, Wuhbet Abraham, Deborah Sementa, Faycal Touti, Derin B Keskin, Catherine J Wu, Darrell J Irvine, Rafael Gomez-Bombarelli, Bradley L Pentelute
Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons. ACS central science 10 (4) (2024)
Aereas Aung, Darrell J Irvine
Modulating Antigen Availability in Lymphoid Organs to Shape the Humoral Immune Response to Vaccines. Journal of immunology (Baltimore, Md. : 1950) 212 (2) (2024)
Nicholas L Truex, Somesh Mohapatra, Mariane Melo, Jacob Rodriguez, Na Li, Wuhbet Abraham, Deborah Sementa, Faycal Touti, Derin B Keskin, Catherine J Wu, Darrell J Irvine, Rafael Gomez-Bombarelli, Bradley L Pentelute
Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons. ACS central science 10 (4) (2024)
Sharanya Sivanand, Yetis Gultekin, Peter S Winter, Sidney Y Vermeulen, Konstantine M Tchourine, Keene L Abbott, Laura V Danai, Florian Gourgue, Brian T Do, Kayla Crowder, Tenzin Kunchok, Allison N Lau, Alicia M Darnell, Alexandria Jefferson, Satoru Morita, Dan G Duda, Andrew J Aguirre, Brian M Wolpin, Nicole Henning, Virginia Spanoudaki, Laura Maiorino, Darrell J Irvine, Ömer H Yilmaz, Caroline A Lewis, Dennis Vitkup, Alex K Shalek, Matthew G Vander Heiden
Cancer tissue of origin constrains the growth and metabolism of metastases. Nature metabolism (2024)
Valerie Lensch, Adele Gabba, Robert Hincapie, Sachin H Bhagchandani, Ankit Basak, Mohammad Murshid Alam, Darrell J Irvine, Alex K Shalek, Jeremiah A Johnson, Neal K Devaraj, Laura L Kiessling
Glycan-costumed virus-like particles promote type 1 anti-tumor immunity. bioRxiv : the preprint server for biology (2024)
Luciano Santollani, Laura Maiorino, Yiming J Zhang, Joseph R Palmeri, Jordan A Stinson, Lauren R Duhamel, Kashif Qureshi, Jack R Suggs, Owen T Porth, William Pinney, Riyam Al Msari, Agnes A Walsh, K Dane Wittrup, Darrell J Irvine
Local delivery of cell surface-targeted immunocytokines programs systemic antitumor immunity. Nature immunology (2024)
Ivan S Pires, Jack R Suggs, Isabella S Carlo, DongSoo Yun, Paula T Hammond, Darrell J Irvine
Surfactant-Mediated Assembly of Precision-Size Liposomes. Chemistry of materials : a publication of the American Chemical Society 36 (15) (2024)
Nicholas L Truex, Somesh Mohapatra, Mariane Melo, Jacob Rodriguez, Na Li, Wuhbet Abraham, Deborah Sementa, Faycal Touti, Derin B Keskin, Catherine J Wu, Darrell J Irvine, Rafael Gomez-Bombarelli, Bradley L Pentelute
Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons. ACS central science 10 (4) (2024)
Ivan S Pires, Jack R Suggs, Isabella S Carlo, DongSoo Yun, Paula T Hammond, Darrell J Irvine
Surfactant-Mediated Assembly of Precision-Size Liposomes. Chemistry of materials : a publication of the American Chemical Society 36 (15) (2024)
Aereas Aung, Darrell J Irvine
Modulating Antigen Availability in Lymphoid Organs to Shape the Humoral Immune Response to Vaccines. Journal of immunology (Baltimore, Md. : 1950) 212 (2) (2024)
Yonger Xue, Yuebao Zhang, Yichen Zhong, Shi Du, Xucheng Hou, Wenqing Li, Haoyuan Li, Siyu Wang, Chang Wang, Jingyue Yan, Diana D Kang, Binbin Deng, David W McComb, Darrell J Irvine, Ron Weiss, Yizhou Dong
LNP-RNA-engineered adipose stem cells for accelerated diabetic wound healing. Nature communications 15 (1) (2024)
Ozgun Kocabiyik, Parastoo Amlashi, A Lina Vo, Heikyung Suh, Sergio A Rodriguez-Aponte, Neil C Dalvie, John Christopher Love, Raiees Andrabi, Darrell J Irvine
Vaccine targeting to mucosal lymphoid tissues promotes humoral immunity in the gastrointestinal tract. Science advances 10 (22) (2024)
Christopher A Cottrell, Payal P Pratap, Kimberly M Cirelli, Diane G Carnathan, Chiamaka A Enemuo, Aleksandar Antanasijevic, Gabriel Ozorowski, Leigh M Sewall, Hongmei Gao, Joel D Allen, Bartek Nogal, Murillo Silva, Jinal Bhiman, Matthias Pauthner, Darrell J Irvine, David Montefiori, Max Crispin, Dennis R Burton, Guido Silvestri, Shane Crotty, Andrew B Ward
Priming antibody responses to the fusion peptide in rhesus macaques. NPJ vaccines 9 (1) (2024)
Aereas Aung, Darrell J Irvine
Modulating Antigen Availability in Lymphoid Organs to Shape the Humoral Immune Response to Vaccines. Journal of immunology (Baltimore, Md. : 1950) 212 (2) (2024)
Valerie Lensch, Adele Gabba, Robert Hincapie, Sachin H Bhagchandani, Ankit Basak, Mohammad Murshid Alam, Jeffery Noble, Darrell J Irvine, Alex K Shalek, Jeremiah A Johnson, Neal K Devaraj, Laura L Kiessling
Carbohydrate-Lectin Interactions Reprogram Dendritic Cells to Promote Type 1 Anti-Tumor Immunity. ACS nano (2024)
Parisa Yousefpour, Yiming J Zhang, Laura Maiorino, Mariane B Melo, Mariluz A Arainga Ramirez, Sidath C Kumarapperuma, Peng Xiao, Murillo Silva, Na Li, Katarzyna K Michaels, Erik Georgeson, Saman Eskandarzadeh, Michael Kubitz, Bettina Groschel, Kashif Qureshi, Jane Fontenot, Lars Hangartner, Rebecca Nedellec, J Christopher Love, Dennis R Burton, William R Schief, Francois J Villinger, Darrell J Irvine
Modulation of antigen delivery and lymph node activation in non-human primates by saponin adjuvant SMNP. bioRxiv : the preprint server for biology (2024)
Christopher A Cottrell, Payal P Pratap, Kimberly M Cirelli, Diane G Carnathan, Chiamaka A Enemuo, Aleksandar Antanasijevic, Gabriel Ozorowski, Leigh M Sewall, Hongmei Gao, Joel D Allen, Bartek Nogal, Murillo Silva, Jinal Bhiman, Matthias Pauthner, Darrell J Irvine, David Montefiori, Max Crispin, Dennis R Burton, Guido Silvestri, Shane Crotty, Andrew B Ward
Priming antibody responses to the fusion peptide in rhesus macaques. NPJ vaccines 9 (1) (2024)
Christopher A Cottrell, Payal P Pratap, Kimberly M Cirelli, Diane G Carnathan, Chiamaka A Enemuo, Aleksandar Antanasijevic, Gabriel Ozorowski, Leigh M Sewall, Hongmei Gao, Joel D Allen, Bartek Nogal, Murillo Silva, Jinal Bhiman, Matthias Pauthner, Darrell J Irvine, David Montefiori, Max Crispin, Dennis R Burton, Guido Silvestri, Shane Crotty, Andrew B Ward
Priming antibody responses to the fusion peptide in rhesus macaques. NPJ vaccines 9 (1) (2024)
Ivan S Pires, Jack R Suggs, Isabella S Carlo, DongSoo Yun, Paula T Hammond, Darrell J Irvine
Surfactant-Mediated Assembly of Precision-Size Liposomes. Chemistry of materials : a publication of the American Chemical Society 36 (15) (2024)
Nicholas L Truex, Somesh Mohapatra, Mariane Melo, Jacob Rodriguez, Na Li, Wuhbet Abraham, Deborah Sementa, Faycal Touti, Derin B Keskin, Catherine J Wu, Darrell J Irvine, Rafael Gomez-Bombarelli, Bradley L Pentelute
Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons. ACS central science 10 (4) (2024)
Kristen A Rodrigues, Yiming J Zhang, Aereas Aung, Duncan M Morgan, Laura Maiorino, Parisa Yousefpour, Grace Gibson, Gabriel Ozorowski, Justin R Gregory, Parastoo Amlashi, Maureen Buckley, Andrew B Ward, William R Schief, J Christopher Love, Darrell J Irvine
Vaccines combining slow delivery and follicle targeting of antigens increase germinal center B cell clonal diversity and clonal expansion. bioRxiv : the preprint server for biology (2024)
Kewen Lei, Darrell J Irvine
A mobile home for T cells. Nature materials 23 (6) (2024)
Aereas Aung, Ang Cui, Laura Maiorino, Ava P Soleimany, Justin R Gregory, Maurice Bukenya, Yiming J Zhang, Heya Lee, Christopher A Cottrell, Duncan M Morgan, Murillo Silva, Heikyung Suh, Jesse D Kirkpatrick, Parastoo Amlashi, Tanaka Remba, Leah M Froehle, Shuhao Xiao, Wuhbet Abraham, Josetta Adams, John Christopher Love, Phillip Huyett, Douglas S Kwon, Nir Hacohen, William R Schief, Sangeeta N Bhatia, Darrell J Irvine
Low protease activity in B cell follicles promotes retention of intact antigens after immunization. Science (New York, N.Y.) 379 (6630) (2023)
Christopher A Cottrell, Payal P Pratap, Kimberly M Cirelli, Diane G Carnathan, Chiamaka A Enemuo, Aleksandar Antanasijevic, Gabriel Ozorowski, Leigh M Sewall, Hongmei Gao, Kelli M Greene, Joel D Allen, Julia T Ngo, Yury Choe, Bartek Nogal, Murillo Silva, Jinal N Bhiman, Matthias G Pauthner, Darrell J Irvine, David C Montefiori, Max Crispin, Dennis R Burton, Guido Silvestri, Shane Crotty, Andrew B Ward
Focusing antibody responses to the fusion peptide in rhesus macaques. bioRxiv : the preprint server for biology (2023)
Aereas Aung, Ang Cui, Laura Maiorino, Ava P Soleimany, Justin R Gregory, Maurice Bukenya, Yiming J Zhang, Heya Lee, Christopher A Cottrell, Duncan M Morgan, Murillo Silva, Heikyung Suh, Jesse D Kirkpatrick, Parastoo Amlashi, Tanaka Remba, Leah M Froehle, Shuhao Xiao, Wuhbet Abraham, Josetta Adams, John Christopher Love, Phillip Huyett, Douglas S Kwon, Nir Hacohen, William R Schief, Sangeeta N Bhatia, Darrell J Irvine
Low protease activity in B cell follicles promotes retention of intact antigens after immunization. Science (New York, N.Y.) 379 (6630) (2023)
Aereas Aung, Ang Cui, Laura Maiorino, Ava P Soleimany, Justin R Gregory, Maurice Bukenya, Yiming J Zhang, Heya Lee, Christopher A Cottrell, Duncan M Morgan, Murillo Silva, Heikyung Suh, Jesse D Kirkpatrick, Parastoo Amlashi, Tanaka Remba, Leah M Froehle, Shuhao Xiao, Wuhbet Abraham, Josetta Adams, John Christopher Love, Phillip Huyett, Douglas S Kwon, Nir Hacohen, William R Schief, Sangeeta N Bhatia, Darrell J Irvine
Low protease activity in B cell follicles promotes retention of intact antigens after immunization. Science (New York, N.Y.) 379 (6630) (2023)
Angela Q Zhang, Alexander Hostetler, Laura E Chen, Vainavi Mukkamala, Wuhbet Abraham, Lucia T Padilla, Alexandra N Wolff, Laura Maiorino, Coralie M Backlund, Aereas Aung, Mariane Melo, Na Li, Shengwei Wu, Darrell J Irvine
Universal redirection of CAR T cells against solid tumours via membrane-inserted ligands for the CAR. Nature biomedical engineering (2023)
Khloe S Gordon, Taeyoon Kyung, Caleb R Perez, Patrick V Holec, Azucena Ramos, Angela Q Zhang, Yash Agarwal, Yunpeng Liu, Catherine E Koch, Alina Starchenko, Brian A Joughin, Douglas A Lauffenburger, Darrell J Irvine, Michael T Hemann, Michael E Birnbaum
Author Correction: Screening for CD19-specific chimaeric antigen receptors with enhanced signalling via a barcoded library of intracellular domains. Nature biomedical engineering (2023)
Aereas Aung, Ang Cui, Laura Maiorino, Ava P Soleimany, Justin R Gregory, Maurice Bukenya, Yiming J Zhang, Heya Lee, Christopher A Cottrell, Duncan M Morgan, Murillo Silva, Heikyung Suh, Jesse D Kirkpatrick, Parastoo Amlashi, Tanaka Remba, Leah M Froehle, Shuhao Xiao, Wuhbet Abraham, Josetta Adams, John Christopher Love, Phillip Huyett, Douglas S Kwon, Nir Hacohen, William R Schief, Sangeeta N Bhatia, Darrell J Irvine
Low protease activity in B cell follicles promotes retention of intact antigens after immunization. Science (New York, N.Y.) 379 (6630) (2023)
Jeong Hyun Lee, Henry J Sutton, Christopher A Cottrell, Ivy Phung, Gabriel Ozorowski, Leigh M Sewall, Rebecca Nedellec, Catherine Nakao, Murillo Silva, Sara T Richey, Jonathan L Torre, Wen-Hsin Lee, Erik Georgeson, Michael Kubitz, Sam Hodges, Tina-Marie Mullen, Yumiko Adachi, Kimberly M Cirelli, Amitinder Kaur, Carolina Allers, Marissa D Fahlberg, Brooke F Grasperge, Jason P Dufour, Faith Schiro, Pyone P Aye, Oleksandr Kalyuzhniy, Alessia Liguori, Diane G Carnathan, Guido Silvestri, Xiaoying Shen, David C Montefiori, Ronald S Veazey, Andrew B Ward, Lars Hangartner, Dennis R Burton, Darrell J Irvine, William R Schief, Shane Crotty
Author Correction: Long-primed germinal centres with enduring affinity maturation and clonal migration. Nature (2023)
Aereas Aung, Ang Cui, Laura Maiorino, Ava P Soleimany, Justin R Gregory, Maurice Bukenya, Yiming J Zhang, Heya Lee, Christopher A Cottrell, Duncan M Morgan, Murillo Silva, Heikyung Suh, Jesse D Kirkpatrick, Parastoo Amlashi, Tanaka Remba, Leah M Froehle, Shuhao Xiao, Wuhbet Abraham, Josetta Adams, John Christopher Love, Phillip Huyett, Douglas S Kwon, Nir Hacohen, William R Schief, Sangeeta N Bhatia, Darrell J Irvine
Low protease activity in B cell follicles promotes retention of intact antigens after immunization. Science (New York, N.Y.) 379 (6630) (2023)
Aereas Aung, Ang Cui, Laura Maiorino, Ava P Soleimany, Justin R Gregory, Maurice Bukenya, Yiming J Zhang, Heya Lee, Christopher A Cottrell, Duncan M Morgan, Murillo Silva, Heikyung Suh, Jesse D Kirkpatrick, Parastoo Amlashi, Tanaka Remba, Leah M Froehle, Shuhao Xiao, Wuhbet Abraham, Josetta Adams, John Christopher Love, Phillip Huyett, Douglas S Kwon, Nir Hacohen, William R Schief, Sangeeta N Bhatia, Darrell J Irvine
Low protease activity in B cell follicles promotes retention of intact antigens after immunization. Science (New York, N.Y.) 379 (6630) (2023)
Zachariah P Tritz, Katayoun Ayasoufi, Delaney M Wolf, Carley A Owens, Courtney S Malo, Benjamin T Himes, Cori E Fain, Emma N Goddery, Lila T Witt, Fang Jin, Michael J Hansen, Ian F Parney, Chensu Wang, Kelly D Moynihan, Darrell J Irvine, Karl Dane Wittrup, Rosa M Diaz Marcano, Richard G Vile, Aaron J Johnson
Anti-PD-1 and extended half-life-IL-2 synergize for treatment of murine glioblastoma independent of host MHC Class I expression. Cancer immunology research (2023)
Sachin H Bhagchandani, Farrukh Vohidov, Lauren E Milling, Evelyn Yuzhou Tong, Christopher M Brown, Michelle L Ramseier, Bin Liu, Timothy B Fessenden, Hung V-T Nguyen, Gavin R Kiel, Lori Won, Robert S Langer, Stefani Spranger, Alex K Shalek, Darrell J Irvine, Jeremiah A Johnson
Engineering kinetics of TLR7/8 agonist release from bottlebrush prodrugs enables tumor-focused immune stimulation. Science advances 9 (16) (2023)
Kristen A Rodrigues, Christopher A Cottrell, Jon M Steichen, Bettina Groschel, Wuhbet Abraham, Heikyung Suh, Yash Agarwal, Kaiyuan Ni, Jason Y H Chang, Parisa Yousefpour, Mariane B Melo, William R Schief, Darrell J Irvine
Optimization of an alum-anchored clinical HIV vaccine candidate. NPJ vaccines 8 (1) (2023)
Nicholas L Truex, Aurélie Rondon, Simon L Rössler, Cameron C Hanna, Yehlin Cho, Bin-You Wang, Coralie M Backlund, Emi A Lutz, Darrell J Irvine, Bradley L Pentelute
Enhanced Vaccine Immunogenicity Enabled by Targeted Cytosolic Delivery of Tumor Antigens into Dendritic Cells. ACS central science 9 (9) (2023)
Ivy Phung, Kristen A Rodrigues, Ester Marina-Zárate, Laura Maiorino, Bapi Pahar, Wen-Hsin Lee, Mariane Melo, Amitinder Kaur, Carolina Allers, Marissa Fahlberg, Brooke F Grasperge, Jason P Dufour, Faith Schiro, Pyone P Aye, Paul G Lopez, Jonathan L Torre, Gabriel Ozorowski, Saman Eskandarzadeh, Michael Kubitz, Erik Georgeson, Bettina Groschel, Rebecca Nedellec, Michael Bick, Katarzyna Kaczmarek Michaels, Hongmei Gao, Xiaoying X Shen, Diane G Carnathan, Guido Silvestri, David C Montefiori, Andrew B Ward, Lars Hangartner, Ronald S Veazey, Dennis R Burton, William R Schief, Darrell J Irvine, Shane Crotty
A combined adjuvant approach primes robust germinal center responses and humoral immunity in non-human primates. Nature communications 14 (1) (2023)
Aereas Aung, Ang Cui, Laura Maiorino, Ava P Soleimany, Justin R Gregory, Maurice Bukenya, Yiming J Zhang, Heya Lee, Christopher A Cottrell, Duncan M Morgan, Murillo Silva, Heikyung Suh, Jesse D Kirkpatrick, Parastoo Amlashi, Tanaka Remba, Leah M Froehle, Shuhao Xiao, Wuhbet Abraham, Josetta Adams, John Christopher Love, Phillip Huyett, Douglas S Kwon, Nir Hacohen, William R Schief, Sangeeta N Bhatia, Darrell J Irvine
Low protease activity in B cell follicles promotes retention of intact antigens after immunization. Science (New York, N.Y.) 379 (6630) (2023)
Jeong Hyun Lee, Henry J Sutton, Christopher A Cottrell, Ivy Phung, Gabriel Ozorowski, Leigh M Sewall, Rebecca Nedellec, Catherine Nakao, Murillo Silva, Sara T Richey, Jonathan L Torre, Wen-Hsin Lee, Erik Georgeson, Michael Kubitz, Sam Hodges, Tina-Marie Mullen, Yumiko Adachi, Kimberly M Cirelli, Amitinder Kaur, Carolina Allers, Marissa D Fahlberg, Brooke F Grasperge, Jason P Dufour, Faith Schiro, Pyone P Aye, Oleksandr Kalyuzhniy, Alessia Liguori, Diane G Carnathan, Guido Silvestri, Xiaoying Shen, David C Montefiori, Ronald S Veazey, Andrew B Ward, Lars Hangartner, Dennis R Burton, Darrell J Irvine, William R Schief, Shane Crotty
Author Correction: Long-primed germinal centres with enduring affinity maturation and clonal migration. Nature (2023)
Ines Mota, Enrico Patrucco, Cristina Mastini, Navin R Mahadevan, Tran C Thai, Elisa Bergaggio, Taek-Chin Cheong, Giulia Leonardi, Elif Karaca-Atabay, Marco Campisi, Teresa Poggio, Matteo Menotti, Chiara Ambrogio, Dario Livio Longo, Susan Klaeger, Hasmik Keshishian, Zsófia M Sztupinszki, Zoltan Szallasi, Derin B Keskin, Jonathan S Duke-Cohan, Bruce Reinhold, Steven A Carr, Catherine J Wu, Kelly D Moynihan, Darrell J Irvine, David A Barbie, Ellis L Reinherz, Claudia Voena, Mark M Awad, Rafael B Blasco, Roberto Chiarle
ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer. Nature cancer (2023)
Bingxu Liu, Rebecca J Carlson, Ivan S Pires, Matteo Gentili, Ellie Feng, Quentin Hellier, Marc Andre Schwartz, Paul C Blainey, Darrell J Irvine, Nir Hacohen
Human STING is a proton channel. Science (New York, N.Y.) 381 (6657) (2023)
Aereas Aung, Ang Cui, Laura Maiorino, Ava P Soleimany, Justin R Gregory, Maurice Bukenya, Yiming J Zhang, Heya Lee, Christopher A Cottrell, Duncan M Morgan, Murillo Silva, Heikyung Suh, Jesse D Kirkpatrick, Parastoo Amlashi, Tanaka Remba, Leah M Froehle, Shuhao Xiao, Wuhbet Abraham, Josetta Adams, John Christopher Love, Phillip Huyett, Douglas S Kwon, Nir Hacohen, William R Schief, Sangeeta N Bhatia, Darrell J Irvine
Low protease activity in B cell follicles promotes retention of intact antigens after immunization. Science (New York, N.Y.) 379 (6630) (2023)
Swati Kataria, Jifa Qi, Ching-Wei Lin, Zhongming Li, Eric L Dane, Archana Mahadevan Iyer, Jay Sacane, Darrell J Irvine, Angela M Belcher
Noninvasive In Vivo Imaging of T-Cells during Cancer Immunotherapy Using Rare-Earth Nanoparticles. ACS nano (2023)
Eike-Christian Wamhoff, Anna Romanov, Hellen Huang, Benjamin J Read, Eric Ginsburg, Grant A Knappe, Hyun Min Kim, Nicholas P Farrell, Darrell J Irvine, Mark Bathe
Controlling Nuclease Degradation of Wireframe DNA Origami with Minor Groove Binders. ACS nano 16 (6) (2022)
Eric L Dane, Alexis Belessiotis-Richards, Coralie M Backlund, Jianing Wang, Kousuke Hidaka, Lauren E Milling, Sachin Bhagchandani, Mariane B Melo, Shengwei Wu, Na Li, Nathan Donahue, Kaiyuan Ni, Leyuan Ma, Masanori Okaniwa, Molly M Stevens, Alfredo Alexander-Katz, Darrell J Irvine
STING agonist delivery by tumour-penetrating PEG-lipid nanodiscs primes robust anticancer immunity. Nature materials 21 (6) (2022)
Khloe S Gordon, Taeyoon Kyung, Caleb R Perez, Patrick V Holec, Azucena Ramos, Angela Q Zhang, Yash Agarwal, Yunpeng Liu, Catherine E Koch, Alina Starchenko, Brian A Joughin, Douglas A Lauffenburger, Darrell J Irvine, Michael T Hemann, Michael E Birnbaum
Screening for CD19-specific chimaeric antigen receptors with enhanced signalling via a barcoded library of intracellular domains. Nature biomedical engineering 6 (7) (2022)
Lawrence P Andrews, Ashwin S Somasundaram, Jessica M Moskovitz, Andrea L Szymczak-Workman, Chang Liu, Anthony R Cillo, Huang Lin, Daniel P Normolle, Kelly D Moynihan, Ichiro Taniuchi, Darrell J Irvine, Joanne M Jeter, Evan J Lipson, Robert L Ferris, Tullia C Bruno, Creg J Workman, Dario A A Vignali
Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding. Science immunology 5 (49) (2022)
Jeong Hyun Lee, Henry J Sutton, Christopher A Cottrell, Ivy Phung, Gabriel Ozorowski, Leigh M Sewall, Rebecca Nedellec, Catherine Nakao, Murillo Silva, Sara T Richey, Jonathan L Torre, Wen-Hsin Lee, Erik Georgeson, Michael Kubitz, Sam Hodges, Tina-Marie Mullen, Yumiko Adachi, Kimberly M Cirelli, Amitinder Kaur, Carolina Allers, Marissa D Fahlberg, Brooke F Grasperge, Jason P Dufour, Faith Schiro, Pyone P Aye, Oleksandr Kalyuzhniy, Alessia Liguori, Diane G Carnathan, Guido Silvestri, Xiaoying Shen, David C Montefiori, Ronald S Veazey, Andrew B Ward, Lars Hangartner, Dennis R Burton, Darrell J Irvine, William R Schief, Shane Crotty
Long-primed germinal centres with enduring affinity maturation and clonal migration. Nature 609 (7929) (2022)
Wan-Ting He, Meng Yuan, Sean Callaghan, Rami Musharrafieh, Sophie Ge Song, Murillo Silva, Nathan Beutler, Wen-Hsin Lee, Peter Yong, Jonathan L Torre, Mariane B Melo, Panpan Zhou, Fangzhu Zhao, Xueyong Zhu, Linghang Peng, Deli Huang, Fabio Anzanello, James Ricketts, Mara Parren, Elijah Garcia, Melissa Ferguson, William Rinaldi, Stephen A Rawlings, David Nemazee, Davey M Smith, Bryan Briney, Yana Safonova, Thomas F Rogers, Jennifer M Dan, Zeli Zhang, Daniela Weiskopf, Alessandro Sette, Shane Crotty, Darrell J Irvine, Andrew B Ward, Ian A Wilson, Dennis R Burton, Raiees Andrabi
Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques. Science translational medicine 14 (657) (2022)
Kavya Rakhra, Wuhbet Abraham, Chensu Wang, Kelly D Moynihan, Na Li, Nathan Donahue, Alexis D Baldeon, Darrell J Irvine
Exploiting albumin as a mucosal vaccine chaperone for robust generation of lung-resident memory T cells. Science immunology 6 (57) (2022)
Yash Agarwal, Lauren E Milling, Jason Y H Chang, Luciano Santollani, Allison Sheen, Emi A Lutz, Anthony Tabet, Jordan Stinson, Kaiyuan Ni, Kristen A Rodrigues, Tyson J Moyer, Mariane B Melo, Darrell J Irvine, Karl Dane Wittrup
Intratumourally injected alum-tethered cytokines elicit potent and safer local and systemic anticancer immunity. Nature biomedical engineering 6 (2) (2022)
Emi A Lutz, Yash Agarwal, Noor Momin, Sarah C Cowles, Joseph R Palmeri, Ellen Duong, Vladlena Hornet, Allison Sheen, Brianna M Lax, Adrienne M Rothschilds, Darrell J Irvine, Stefani Spranger, Karl Dane Wittrup
Alum-anchored intratumoral retention improves the tolerability and antitumor efficacy of type I interferon therapies. Proceedings of the National Academy of Sciences of the United States of America 119 (36) (2022)
Jason Y H Chang, Yash Agarwal, Kristen A Rodrigues, Noor Momin, Kaiyuan Ni, Benjamin J Read, Tyson J Moyer, Naveen K Mehta, Murillo Silva, Heikyung Suh, Mariane B Melo, K Dane Wittrup, Darrell J Irvine
Co-Anchoring of Engineered Immunogen and Immunostimulatory Cytokines to Alum Promotes Enhanced-Humoral Immunity. Advanced therapeutics 5 (7) (2022)
Brittany L Hartwell, Mariane B Melo, Peng Xiao, Ashley A Lemnios, Na Li, Jason Y H Chang, Jingyou Yu, Makda S Gebre, Aiquan Chang, Laura Maiorino, Crystal Carter, Tyson J Moyer, Neil C Dalvie, Sergio A Rodriguez-Aponte, Kristen A Rodrigues, Murillo Silva, Heikyung Suh, Josetta Adams, Jane Fontenot, John Christopher Love, Dan H Barouch, François J Villinger, Ruth M Ruprecht, Darrell J Irvine
Intranasal vaccination with lipid-conjugated immunogens promotes antigen transmucosal uptake to drive mucosal and systemic immunity. Science translational medicine 14 (654) (2022)
Coralie M Backlund, Rebecca L Holden, Kelly D Moynihan, Daniel Garafola, Charlotte E Farquhar, Naveen K Mehta, Laura Maiorino, Sydney Pham, J Bryan Iorgulescu, David A Reardon, Catherine J Wu, Bradley L Pentelute, Darrell J Irvine
Cell-penetrating peptides enhance peptide vaccine accumulation and persistence in lymph nodes to drive immunogenicity. Proceedings of the National Academy of Sciences of the United States of America 119 (32) (2022)
Darrell J Irvine, Marcela V Maus, David J Mooney, Wilson W Wong
The future of engineered immune cell therapies. Science (New York, N.Y.) 378 (6622) (2022)
Chase D McCann, Christiaan H van Dorp, Ali Danesh, Adam R Ward, Thomas R Dilling, Talia M Mota, Elizabeth Zale, Eva M Stevenson, Shabnum Patel, Chanson J Brumme, Winnie Dong, Douglas S Jones, Thomas Lars Andresen, Bruce D Walker, Zabrina L Brumme, Catherine M Bollard, Alan S Perelson, Darrell J Irvine, R Brad Jones
A participant-derived xenograft model of HIV enables long-term evaluation of autologous immunotherapies. The Journal of experimental medicine 218 (7) (2021)
Neil C Dalvie, Sergio A Rodriguez-Aponte, Brittany L Hartwell, Lisa H Tostanoski, Andrew M Biedermann, Laura E Crowell, Kawaljit Kaur, Ozan S Kumru, Lauren Carter, Jingyou Yu, Aiquan Chang, Katherine McMahan, Thomas Courant, Celia Lebas, Ashley A Lemnios, Kristen A Rodrigues, Murillo Silva, Ryan S Johnston, Christopher A Naranjo, Mary Kate Tracey, Joseph R Brady, Charles A Whittaker, Dongsoo Yun, Natalie Brunette, Jing Yang John Wang, Carl Walkey, Brooke Fiala, Swagata Kar, Maciel Porto, Megan Lok, Hanne Andersen, Mark G Lewis, Kerry R Love, Danielle L Camp, Judith Maxwell Silverman, Harry Kleanthous, Sangeeta B Joshi, David B Volkin, Patrice M Dubois, Nicolas Collin, Neil P King, Dan H Barouch, Darrell J Irvine, John Christopher Love
Engineered SARS-CoV-2 receptor binding domain improves manufacturability in yeast and immunogenicity in mice. Proceedings of the National Academy of Sciences of the United States of America 118 (38) (2021)
Kristen A Rodrigues, Sergio A Rodriguez-Aponte, Neil C Dalvie, Jeong Hyun Lee, Wuhbet Abraham, Diane G Carnathan, Luis E Jimenez, Julia T Ngo, Jason Y H Chang, Zeli Zhang, Jingyou Yu, Aiquan Chang, Catherine Nakao, Benjamin Goodwin, Christopher A Naranjo, Libin Zhang, Murillo Silva, Dan H Barouch, Guido Silvestri, Shane Crotty, John Christopher Love, Darrell J Irvine
Phosphate-mediated coanchoring of RBD immunogens and molecular adjuvants to alum potentiates humoral immunity against SARS-CoV-2. Science advances 7 (50) (2021)
Shengnan Huang, Ching-Wei Lin, Jifa Qi, Archana Mahadevan Iyer, Yanpu He, Yingzhong Li, Neelkanth M Bardhan, Darrell J Irvine, Paula T Hammond, Angela M Belcher
Surface Plasmon-Enhanced Short-Wave Infrared Fluorescence for Detecting Sub-Millimeter-Sized Tumors. Advanced materials (Deerfield Beach, Fla.) 33 (7) (2021)
Ganapathy Sriram, Lauren E Milling, Jung-Kuei Chen, Yi Wen Kong, Brian A Joughin, Wuhbet Abraham, Susanne Swartwout, Erika D Handly, Darrell J Irvine, Micheal B Yaffe
The injury response to DNA damage in live tumor cells promotes antitumor immunity. Science signaling 14 (705) (2021)
Grant A Knappe, Eike-Christian Wamhoff, Benjamin J Read, Darrell J Irvine, Mark Bathe
In Situ Covalent Functionalization of DNA Origami Virus-like Particles. ACS nano 15 (9) (2021)
Amelia Escolano, Harry B Gristick, Rajeev Gautam, Andrew T DeLaitsch, Morgan E Abernathy, Zhi Yang, Haoqing Wang, Magnus A G Hoffmann, Yoshiaki Nishimura, Zijun Wang, Nicholas Koranda, Leesa M Kakutani, Han Gao, Priyanthi N P Gnanapragasam, Henna Raina, Anna Gazumyan, Melissa Cipolla, Thiago Y Oliveria, Victor Ramos, Darrell J Irvine, Murillo Silva, Anthony P West, Jennifer R Keeffe, Christopher O Barnes, Michael S Seaman, Michel C Nussenzweig, Malcolm A Martin, Pamela J Bjorkman
Sequential immunization of macaques elicits heterologous neutralizing antibodies targeting the V3-glycan patch of HIV-1 Env. Science translational medicine 13 (621) (2021)
Murillo Silva, Yu Kato, Mariane B Melo, Ivy Phung, Brian L Freeman, Zhongming Li, Kangsan Roh, Jan Willem Van Wijnbergen, Hannah Watkins, Chiamaka A Enemuo, Brittany L Hartwell, Jason Y H Chang, Shuhao Xiao, Kristen A Rodrigues, Kimberly M Cirelli, Na Li, Sonya Haupt, Aereas Aung, Benjamin Cossette, Wuhbet Abraham, Swati Kataria, Raiza Bastidas, Jinal N Bhiman, Caitlyn H Linde, Nathaniel I Bloom, Bettina Groschel, Erik Georgeson, Nicole Phelps, Ayush Thomas, Julia Bals, Diane G Carnathan, Daniel Lingwood, Dennis R Burton, Galit Alter, Timothy P Padera, Angela M Belcher, William R Schief, Guido Silvestri, Ruth M Ruprecht, Shane Crotty, Darrell J Irvine
A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity. Science immunology 6 (66) (2021)
Alexander R Loftis, Genwei Zhang, Coralie M Backlund, Anthony J Quartararo, Novalia Pishesha, Cameron C Hanna, Carly K Schissel, Daniel Garafola, Andrei Loas, R John Collier, Hidde L Ploegh, Darrell J Irvine, Bradley L Pentelute
An in vivo selection-derived d-peptide for engineering erythrocyte-binding antigens that promote immune tolerance. Proceedings of the National Academy of Sciences of the United States of America 118 (34) (2021)
Siawosh K Eskandari, Ina Sulkaj, Mariane B Melo, Na Li, Hazim Allos, Juliano B Alhaddad, Branislav Kollar, Thiago J Borges, Arach S Eskandari, Max A Zinter, Songjie Cai, Jean Pierre Assaker, John Y Choi, Basmah S Al Dulaijan, Amr Mansouri, Yousef Haik, Bakhos A Tannous, Willem J van Son, Hendrik Gerrit Derk Leuvenink, Bohdan Pomahac, Leonardo V Riella, Li Tang, Marc A J Seelen, Darrell J Irvine, Jamil R Azzi
Regulatory T cells engineered with TCR signaling-responsive IL-2 nanogels suppress alloimmunity in sites of antigen encounter. Science translational medicine 12 (569) (2021)
Hannah L Turner, Raiees Andrabi, Christopher A Cottrell, Sara T Richey, Sophie Ge Song, Sean Callaghan, Fabio Anzanello, Tyson J Moyer, Wuhbet Abraham, Mariane B Melo, Murillo Silva, Nicole Scaringi, Eva G Rakasz, Quentin J Sattentau, Darrell J Irvine, Dennis R Burton, Andrew B Ward
Disassembly of HIV envelope glycoprotein trimer immunogens is driven by antibodies elicited via immunization. Science advances 7 (31) (2021)
Naveen K Mehta, Roma V Pradhan, Ava P Soleimany, Kelly D Moynihan, Adrienne M Rothschilds, Noor Momin, Kavya Rakhra, Jordi Mata-Fink, Sangeeta N Bhatia, Karl Dane Wittrup, Darrell J Irvine
Pharmacokinetic tuning of protein-antigen fusions enhances the immunogenicity of T-cell vaccines. Nature biomedical engineering 4 (6) (2020)
Rémi Veneziano, Tyson J Moyer, Matthew B Stone, Eike-Christian Wamhoff, Benjamin J Read, Sayak Mukherjee, Tyson R Shepherd, Jayajit Das, William R Schief, Darrell J Irvine, Mark Bathe
Role of nanoscale antigen organization on B-cell activation probed using DNA origami. Nature nanotechnology 15 (8) (2020)
Farrukh Vohidov, Lauren E Milling, Qixian Chen, Wenxu Zhang, Sachin Bhagchandani, Hung V-T Nguyen, Darrell J Irvine, Jeremiah A Johnson
ABC triblock bottlebrush copolymer-based injectable hydrogels: design, synthesis, and application to expanding the therapeutic index of cancer immunochemotherapy. Chemical science 11 (23) (2020)
Darrell J Irvine, Eric L Dane
Enhancing cancer immunotherapy with nanomedicine. Nature reviews. Immunology 20 (5) (2020)
Tyson J Moyer, Yu Kato, Wuhbet Abraham, Jason Y H Chang, Daniel W Kulp, Nicki Watson, Hannah L Turner, Sergey Menis, Robert K Abbott, Jinal N Bhiman, Mariane B Melo, Hayley A Simon, Sara Herrera-De la Mata, Shu Liang, Grégory Seumois, Yash Agarwal, Na Li, Dennis R Burton, Andrew B Ward, William R Schief, Shane Crotty, Darrell J Irvine
Engineered immunogen binding to alum adjuvant enhances humoral immunity. Nature medicine 26 (3) (2020)
Leyuan Ma, Tanmay Dichwalkar, Jason Y H Chang, Benjamin Cossette, Daniel Garafola, Angela Q Zhang, Michael Fichter, Chensu Wang, Simon Liang, Murillo Silva, Sudha Kumari, Naveen K Mehta, Wuhbet Abraham, Nikki Thai, Na Li, Karl Dane Wittrup, Darrell J Irvine
Enhanced CAR-T cell activity against solid tumors by vaccine boosting through the chimeric receptor. Science (New York, N.Y.) 365 (6449) (2020)
Sudha Kumari, Michael Mak, Yeh-Chuin Poh, Mira Tohme, Nicki Watson, Mariane Melo, Erin Janssen, Michael L Dustin, Raif Geha, Darrell J Irvine
Cytoskeletal tension actively sustains the migratory T-cell synaptic contact. The EMBO journal 39 (5) (2020)
Antonio E Barberio, Sean G Smith, Santiago Correa, Cathy Nguyen, Bang Nhan, Mariane Melo, Talar Tokatlian, Heikyung Suh, Darrell J Irvine, Paula T Hammond
Cancer Cell Coating Nanoparticles for Optimal Tumor-Specific Cytokine Delivery. ACS nano 14 (9) (2020)
Jacob T Martin, Christopher A Cottrell, Aleksandar Antanasijevic, Diane G Carnathan, Benjamin J Cossette, Chiamaka A Enemuo, Etse H Gebru, Yury Choe, Federico Viviano, Stephanie Fischinger, Talar Tokatlian, Kimberly M Cirelli, George Ueda, Jeffrey Copps, Torben Schiffner, Sergey Menis, Galit Alter, William R Schief, Shane Crotty, Neil P King, David Baker, Guido Silvestri, Andrew B Ward, Darrell J Irvine
Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations. NPJ vaccines 5 (1) (2020)
Noor Momin, Naveen K Mehta, Nitasha R Bennett, Leyuan Ma, Joseph R Palmeri, Magnolia M Chinn, Emi A Lutz, Byong Ha Kang, Darrell J Irvine, Stefani Spranger, Karl Dane Wittrup
Anchoring of intratumorally administered cytokines to collagen safely potentiates systemic cancer immunotherapy. Science translational medicine 11 (498) (2020)
Yanpu He, Celestine Hong, Emily Z Yan, Samantha J Fletcher, Ge Zhu, Mengdi Yang, Yingzhong Li, Xin Sun, Darrell J Irvine, Jiahe Li, Paula T Hammond
Self-assembled cGAMP-STINGΔTM signaling complex as a bioinspired platform for cGAMP delivery. Science advances 6 (24) (2020)
Dana Al Sulaiman, Jason Y H Chang, Nitasha R Bennett, Helena Topouzi, Claire A Higgins, Darrell J Irvine, Sylvain Ladame
Hydrogel-Coated Microneedle Arrays for Minimally Invasive Sampling and Sensing of Specific Circulating Nucleic Acids from Skin Interstitial Fluid. ACS nano 13 (8) (2019)
Timothy J Deming, Harm-Anton Klok, Steven P Armes, Matthew L Becker, Julie A Champion, Eugene Y-X Chen, Sarah C Heilshorn, Jan C M Van Hest, Darrell J Irvine, Jeremiah A Johnson, Laura L Kiessling, Heather D Maynard, Monica Olvera de la Cruz, Millicent O Sullivan, Matthew V Tirrell, Livia S A Passos, Se Bastien Lecommandoux, Simona Percec, Zhiyuan Zhong, Ann-Christine Albertsson
Polymers at the Interface with Biology. Biomacromolecules 19 (8) (2019)
Anasuya Mandal, Archana V Boopathy, Lionel K W Lam, Kelly D Moynihan, Mary E Welch, Nitasha R Bennett, Michelle E Turvey, Nikki Thai, Jenny H Van, John Christopher Love, Paula T Hammond, Darrell J Irvine
Cell and fluid sampling microneedle patches for monitoring skin-resident immunity. Science translational medicine 10 (467) (2019)
Talar Tokatlian, Benjamin J Read, Christopher A Jones, Daniel W Kulp, Sergey Menis, Jason Y H Chang, Jon M Steichen, Sudha Kumari, Joel D Allen, Eric L Dane, Alessia Liguori, Maya Sangesland, Daniel Lingwood, Max Crispin, William R Schief, Darrell J Irvine
Innate immune recognition of glycans targets HIV nanoparticle immunogens to germinal centers. Science (New York, N.Y.) 363 (6427) (2018)
Prabhani U Atukorale, Zekiye P Guven, Ahmet Bekdemir, Randy P Carney, Reid C Van Lehn, Dong Soo Yun, Paulo H Jacob Silva, Davide Demurtas, Yu-Sang Yang, Alfredo Alexander-Katz, Francesco Stellacci, Darrell J Irvine
Structure-Property Relationships of Amphiphilic Nanoparticles That Penetrate or Fuse Lipid Membranes. Bioconjugate chemistry 29 (4) (2018)
Yanpu He, Celestine Hong, Jiahe Li, MayLin T Howard, Yingzhong Li, Michelle E Turvey, Divakara S S M Uppu, John R Martin, Ketian Zhang, Darrell J Irvine, Paula T Hammond
Synthetic Charge-Invertible Polymer for Rapid and Complete Implantation of Layer-by-Layer Microneedle Drug Films for Enhanced Transdermal Vaccination. ACS nano 12 (10) (2018)
Jiahe Li, Wade Wang, Yanpu He, Yingzhong Li, Emily Z Yan, Ketian Zhang, Darrell J Irvine, Paula T Hammond
Structurally Programmed Assembly of Translation Initiation Nanoplex for Superior mRNA Delivery. ACS nano 11 (3) (2017)

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Darrell J Irvine