Lefu Lan

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 34

Top Venues

Virulence

The Journal of organic chemistry

Nature communications

PLoS pathogens

Shanghai Institute of Materia Medica Chinese Academy of Sciences

Chinese Academy of Sciences (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Shanghai Institute of Materia Medica Chinese Academy of Sciences Jun 01 2010

China

Professor

University of Chicago Jan 01 2007 - May 01 2010

United States

Post-doctoral scientist

Kansas State University Oct 08 2004 - Dec 31 2006

United States

Post-doctoral scientist

Education History

Chinese Academy of Sciences Sep 01 2000 - Mar 31 2004

China

PHD

Sichuan University Sep 01 1997 - Jul 01 2000

China

MSC

Sichuan University Sep 01 1993 - Jul 01 1997

China

BSC

Publications

Feifei Chen, Qingmin Zhao, Ziqiong Yang, Rongrong Chen, Huiwen Pan, Yanhui Wang, Huan Liu, Qiao Cao, Jianhua Gan, Xia Liu, Naixia Zhang, Cai-Guang Yang, Haihua Liang, Lefu Lan
Citrate serves as a signal molecule to modulate carbon metabolism and iron homeostasis in Staphylococcus aureus. PLoS pathogens 20 (7) (2024)
Feifei Chen, Qingmin Zhao, Ziqiong Yang, Rongrong Chen, Huiwen Pan, Yanhui Wang, Huan Liu, Qiao Cao, Jianhua Gan, Xia Liu, Naixia Zhang, Cai-Guang Yang, Haihua Liang, Lefu Lan
Citrate serves as a signal molecule to modulate carbon metabolism and iron homeostasis in Staphylococcus aureus. PLoS pathogens 20 (7) (2024)
Feifei Chen, Qingmin Zhao, Ziqiong Yang, Rongrong Chen, Huiwen Pan, Yanhui Wang, Huan Liu, Qiao Cao, Jianhua Gan, Xia Liu, Naixia Zhang, Cai-Guang Yang, Haihua Liang, Lefu Lan
Citrate serves as a signal molecule to modulate carbon metabolism and iron homeostasis in Staphylococcus aureus. PLoS pathogens 20 (7) (2024)
Feifei Chen, Qingmin Zhao, Ziqiong Yang, Rongrong Chen, Huiwen Pan, Yanhui Wang, Huan Liu, Qiao Cao, Jianhua Gan, Xia Liu, Naixia Zhang, Cai-Guang Yang, Haihua Liang, Lefu Lan
Citrate serves as a signal molecule to modulate carbon metabolism and iron homeostasis in Staphylococcus aureus. PLoS pathogens 20 (7) (2024)
Dongliang Guan, Feifei Chen, Wei Shi, Lefu Lan, Wei Huang
Single Modification at the N-Terminus of Norvancomycin to Combat Drug-Resistant Gram-Positive Bacteria. ChemMedChem (2023)
Feifei Chen, Hongxia Di, Yanhui Wang, Chao Peng, Rongrong Chen, Huiwen Pan, Cai-Guang Yang, Haihua Liang, Lefu Lan
The enzyme activity of sortase A is regulated by phosphorylation in Staphylococcus aureus . Virulence 14 (1) (2023)
Feifei Chen, Hongxia Di, Yanhui Wang, Chao Peng, Rongrong Chen, Huiwen Pan, Cai-Guang Yang, Haihua Liang, Lefu Lan
The enzyme activity of sortase A is regulated by phosphorylation in Staphylococcus aureus . Virulence 14 (1) (2023)
Yunfu Lu, Feifei Chen, Qingmin Zhao, Qiao Cao, Rongrong Chen, Huiwen Pan, Yanhui Wang, Haixin Huang, Ruimin Huang, Qian Liu, Min Li, Taeok Bae, Haihua Liang, Lefu Lan
Modulation of MRSA virulence gene expression by the wall teichoic acid enzyme TarO. Nature communications 14 (1) (2023)
Feifei Chen, Hongxia Di, Yanhui Wang, Chao Peng, Rongrong Chen, Huiwen Pan, Cai-Guang Yang, Haihua Liang, Lefu Lan
The enzyme activity of sortase A is regulated by phosphorylation in Staphylococcus aureus . Virulence 14 (1) (2023)
Huajian Zhu, Jiang Wang, Yunfu Lu, Vadim A Soloshonok, Lefu Lan, Jinyi Xu, Hong Liu
Pd(II) Complexes of Chiral Proline-Derived Ligands: Application for Dynamic Thermodynamic Resolution of α-Amino Acids and Their Antibacterial Activities. The Journal of organic chemistry (2023)
Huajian Zhu, Jiang Wang, Yunfu Lu, Vadim A Soloshonok, Lefu Lan, Jinyi Xu, Hong Liu
Pd(II) Complexes of Chiral Proline-Derived Ligands: Application for Dynamic Thermodynamic Resolution of α-Amino Acids and Their Antibacterial Activities. The Journal of organic chemistry 88 (6) (2023)
Yunfu Lu, Feifei Chen, Qingmin Zhao, Qiao Cao, Rongrong Chen, Huiwen Pan, Yanhui Wang, Haixin Huang, Ruimin Huang, Qian Liu, Min Li, Taeok Bae, Haihua Liang, Lefu Lan
Modulation of MRSA virulence gene expression by the wall teichoic acid enzyme TarO. Nature communications 14 (1) (2023)
Feifei Chen, Hongxia Di, Yanhui Wang, Chao Peng, Rongrong Chen, Huiwen Pan, Cai-Guang Yang, Haihua Liang, Lefu Lan
The enzyme activity of sortase A is regulated by phosphorylation in Staphylococcus aureus . Virulence 14 (1) (2023)
Feifei Chen, Hongxia Di, Yanhui Wang, Chao Peng, Rongrong Chen, Huiwen Pan, Cai-Guang Yang, Haihua Liang, Lefu Lan
The enzyme activity of sortase A is regulated by phosphorylation in Staphylococcus aureus . Virulence 14 (1) (2023)
Feifei Chen, Hongxia Di, Yanhui Wang, Chao Peng, Rongrong Chen, Huiwen Pan, Cai-Guang Yang, Haihua Liang, Lefu Lan
The enzyme activity of sortase A is regulated by phosphorylation in Staphylococcus aureus . Virulence (2023)
Huajian Zhu, Jiang Wang, Yunfu Lu, Vadim A Soloshonok, Lefu Lan, Jinyi Xu, Hong Liu
Pd(II) Complexes of Chiral Proline-Derived Ligands: Application for Dynamic Thermodynamic Resolution of α-Amino Acids and Their Antibacterial Activities. The Journal of organic chemistry 88 (6) (2023)
Shugang Qin, Wen Xiao, Chuanmin Zhou, Qinqin Pu, Xin Deng, Lefu Lan, Haihua Liang, Xiangrong Song, Mingshan Jiang
Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics. Signal transduction and targeted therapy 7 (1) (2022)
Huajian Zhu, Jiang Wang, Yunfu Lu, Vadim A Soloshonok, Lefu Lan, Jinyi Xu, Hong Liu
Cu(II) Complexes with Proline-Derived Schiff Base Ligand: Chemical Resolution of N , C -Unprotected α-Amino Acids and Their Antibacterial Activity. The Journal of organic chemistry 87 (19) (2022)
Bingyan Wei, Tao Zhang, Pengyu Wang, Yihui Pan, Jiahui Li, Weizhong Chen, Min Zhang, Quanjiang Ji, Wenjuan Wu, Lefu Lan, Jianhua Gan, Cai-Guang Yang
Anti-infective therapy using species-specific activators of Staphylococcus aureus ClpP. Nature communications 13 (1) (2022)
Bao Chen, Qingmin Zhao, Yu-Cheng Gu, Lefu Lan, Chang-Yun Wang, Yue-Wei Guo
Xishaeleganins A-D, Sesquiterpenoid Hydroquinones from Xisha Marine Sponge Dactylospongia elegans . Marine drugs 20 (2) (2022)
Bao Chen, Peiju Qiu, Baofu Xu, Qingmin Zhao, Yu-Cheng Gu, Lei Fu, Shijie Bi, Lefu Lan, Chang-Yun Wang, Yue-Wei Guo
Cytotoxic and Antibacterial Isomalabaricane Terpenoids from the Sponge Rhabdastrella globostellata . Journal of natural products 85 (7) (2022)
Jian Li, Dongliang Guan, Feifei Chen, Weiwei Shi, Lefu Lan, Wei Huang
Total and Semisyntheses of Polymyxin Analogues with 2-Thr or 10-Thr Modifications to Decipher the Structure-Activity Relationship and Improve the Antibacterial Activity. Journal of medicinal chemistry 64 (9) (2021)
Chenchen Xu, Qiao Cao, Lefu Lan
Glucose-Binding of Periplasmic Protein GltB Activates GtrS-GltR Two-Component System in Pseudomonas aeruginosa. Microorganisms 9 (2) (2021)
Ke Fan, Qiao Cao, Lefu Lan
Genome-Wide Mapping Reveals Complex Regulatory Activities of BfmR in Pseudomonas aeruginosa. Microorganisms 9 (3) (2021)
Qiao Cao, Nana Yang, Yanhui Wang, Chenchen Xu, Xue Zhang, Ke Fan, Feifei Chen, Haihua Liang, Yingchao Zhang, Xin Deng, You-Jun Feng, Cai-Guang Yang, Mingshan Jiang, Taeok Bae, Lefu Lan
Mutation-induced remodeling of the BfmRS two-component system in Pseudomonas aeruginosa clinical isolates. Science signaling 13 (656) (2020)
Teng Yang, Tao Zhang, Xiang-Na Guan, Ze Dong, Lefu Lan, Song Yang, Cai-Guang Yang
Tideglusib and Its Analogues As Inhibitors of Staphylococcus aureus SrtA. Journal of medicinal chemistry 63 (15) (2020)
Nana Yang, Qiao Cao, Shuyang Hu, Chenchen Xu, Ke Fan, Feifei Chen, Cai-Guang Yang, Haihua Liang, Min Wu, Taeok Bae, Lefu Lan
Alteration of protein homeostasis mediates the interaction of Pseudomonas aeruginosa with Staphylococcus aureus. Molecular microbiology 114 (3) (2020)
Dongliang Guan, Feifei Chen, Yunguang Qiu, Bofeng Jiang, Likun Gong, Lefu Lan, Wei Huang
Sulfonium, an Underestimated Moiety for Structural Modification, Alters the Antibacterial Profile of Vancomycin Against Multidrug-Resistant Bacteria. Angewandte Chemie (International ed. in English) 58 (20) (2019)
Teng Yang, Tingting Liu, Jianhua Gan, Kunqian Yu, Kaixian Chen, Wei Xue, Lefu Lan, Song Yang, Cai-Guang Yang
Structural Insight into the Mechanism of Staphylococcus aureus Stp1 Phosphatase. ACS infectious diseases 5 (6) (2019)
Ping Lin, Qinqin Pu, Qun Wu, Chuanmin Zhou, Biao Wang, Jacob Schettler, Zhihan Wang, Shugang Qin, Pan Gao, Rongpeng Li, Guoping Li, Zhengyu Cheng, Lefu Lan, Jianxin Jiang, Mingshan Jiang
High-throughput screen reveals sRNAs regulating crRNA biogenesis by targeting CRISPR leader to repress Rho termination. Nature communications 10 (1) (2019)
Dongliang Guan, Feifei Chen, Lun Xiong, Feng Tang, null Faridoon, Yunguang Qiu, Naixia Zhang, Likun Gong, Jian Li, Lefu Lan, Wei Huang
Extra Sugar on Vancomycin: New Analogues for Combating Multidrug-Resistant Staphylococcus aureus and Vancomycin-Resistant Enterococci. Journal of medicinal chemistry 61 (1) (2018)
Baoli Li, Shuaishuai Ni, Feifei Chen, Fei Mao, Hanwen Wei, Yifu Liu, Jin Zhu, Lefu Lan, Jian Li
Discovery of Potent Benzocycloalkane Derived Diapophytoene Desaturase Inhibitors with an Enhanced Safety Profile for the Treatment of MRSA, VISA, and LRSA Infections. ACS infectious diseases 4 (3) (2018)
Baoli Li, Shuaishuai Ni, Fei Mao, Feifei Chen, Yifu Liu, Hanwen Wei, Wenhua Chen, Jin Zhu, Lefu Lan, Jian Li
Novel Terminal Bipheny-Based Diapophytoene Desaturases (CrtN) Inhibitors as Anti-MRSA/VISR/LRSA Agents with Reduced hERG Activity. Journal of medicinal chemistry 61 (1) (2017)
Feifei Chen, Hongxia Di, Youxin Wang, Qiao Cao, Bin Xu, Xue Zhang, Nana Yang, Guijie Liu, Cai-Guang Yang, Yong Xu, Hualiang Jiang, Fulin Lian, Naixia Zhang, Jian Li, Lefu Lan
Small-molecule targeting of a diapophytoene desaturase inhibits S. aureus virulence. Nature chemical biology 12 (3) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Lefu Lan