Lei Xie

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 25

Top Topics

Machine Learning

Top Venues

PLoS computational biology

Nature machine intelligence

This page only lists publications with an associated author ORCID identifier.

Publications

You Wu, Li Xie, Yang Liu, Lei Xie
Semi-supervised meta-learning elucidates understudied molecular interactions. Communications biology 7 (1) (2024)
Yiyan Yang, Keith Dufault-Thompson, Wei Yan, Tian Cai, Lei Xie, Xiaofang Jiang
Large-scale genomic survey with deep learning-based method reveals strain-level phage specificity determinants. GigaScience 13 (2024)
Yiyan Yang, Keith Dufault-Thompson, Wei Yan, Tian Cai, Lei Xie, Xiaofang Jiang
Large-scale genomic survey with deep learning-based method reveals strain-level phage specificity determinants. GigaScience 13 (2024)
Yiyan Yang, Keith Dufault-Thompson, Wei Yan, Tian Cai, Lei Xie, Xiaofang Jiang
Large-scale genomic survey with deep learning-based method reveals strain-level phage specificity determinants. GigaScience 13 (2024)
Tian Cai, Li Xie, Shuo Zhang, Muge Chen, Di He, Amitesh Badkul, Yang Liu, Hari Krishna Namballa, Michael Dorogan, Wayne W Harding, Cameron Mura, Philip E Bourne, Lei Xie
End-to-end sequence-structure-function meta-learning predicts genome-wide chemical-protein interactions for dark proteins. PLoS computational biology 19 (1) (2023)
Li Xie, Lei Xie
Elucidation of Genome-wide Understudied Proteins targeted by PROTAC-induced degradation using Interpretable Machine Learning. bioRxiv : the preprint server for biology (2023)
Tian Cai, Li Xie, Shuo Zhang, Muge Chen, Di He, Amitesh Badkul, Yang Liu, Hari Krishna Namballa, Michael Dorogan, Wayne W Harding, Cameron Mura, Philip E Bourne, Lei Xie
End-to-end sequence-structure-function meta-learning predicts genome-wide chemical-protein interactions for dark proteins. PLoS computational biology 19 (1) (2023)
Cameron Mura, Emma Candelier, Lei Xie
A Tribute to Phil Bourne-Scientist and Human. Biomolecules 13 (1) (2023)
Li Xie, Lei Xie
Elucidation of genome-wide understudied proteins targeted by PROTAC-induced degradation using interpretable machine learning. PLoS computational biology 19 (8) (2023)
Cameron Mura, Emma Candelier, Lei Xie
A Tribute to Phil Bourne-Scientist and Human. Biomolecules 13 (1) (2023)
Tian Cai, Li Xie, Shuo Zhang, Muge Chen, Di He, Amitesh Badkul, Yang Liu, Hari Krishna Namballa, Michael Dorogan, Wayne W Harding, Cameron Mura, Philip E Bourne, Lei Xie
End-to-end sequence-structure-function meta-learning predicts genome-wide chemical-protein interactions for dark proteins. PLoS computational biology 19 (1) (2023)
Cameron Mura, Emma Candelier, Lei Xie
A Tribute to Phil Bourne-Scientist and Human. Biomolecules 13 (1) (2023)
Tian Cai, Li Xie, Shuo Zhang, Muge Chen, Di He, Amitesh Badkul, Yang Liu, Hari Krishna Namballa, Michael Dorogan, Wayne W Harding, Cameron Mura, Philip E Bourne, Lei Xie
End-to-end sequence-structure-function meta-learning predicts genome-wide chemical-protein interactions for dark proteins. PLoS computational biology 19 (1) (2023)
Li Xie, Lei Xie
Elucidation of Genome-wide Understudied Proteins targeted by PROTAC-induced degradation using Interpretable Machine Learning. bioRxiv : the preprint server for biology (2023)
Yang Liu, Hansaim Lim, Lei Xie
Exploration of chemical space with partial labeled noisy student self-training and self-supervised graph embedding. BMC bioinformatics 23 (Suppl 3) (2022)
Qiao Liu, Bohyun Lee, Lei Xie
Small molecule modulation of microbiota: a systems pharmacology perspective. BMC bioinformatics 23 (Suppl 3) (2022)
You Wu, Qiao Liu, Yue Qiu, Lei Xie
Deep learning prediction of chemical-induced dose-dependent and context-specific multiplex phenotype responses and its application to personalized alzheimer's disease drug repurposing. PLoS computational biology 18 (8) (2022)
Di He, Qiao Liu, You Wu, Lei Xie
A context-aware deconfounding autoencoder for robust prediction of personalized clinical drug response from cell-line compound screening. Nature machine intelligence 4 (10) (2022)
Di He, Qiao Liu, You Wu, Lei Xie
A context-aware deconfounding autoencoder for robust prediction of personalized clinical drug response from cell-line compound screening. Nature machine intelligence 4 (10) (2022)
Di He, Qiao Liu, You Wu, Lei Xie
A context-aware deconfounding autoencoder for robust prediction of personalized clinical drug response from cell-line compound screening. Nature machine intelligence 4 (10) (2022)
Qiao Liu, Lei Xie
TranSynergy: Mechanism-driven interpretable deep neural network for the synergistic prediction and pathway deconvolution of drug combinations. PLoS computational biology 17 (2) (2021)
Faten A Sayed, Lay Kodama, Li Fan, Gillian K Carling, Joe C Udeochu, David Le, Qingyun Li, Lu Zhou, Man Ying Wong, Rose Horowitz, Pearly Ye, Hansruedi Mathys, Minghui Wang, Xiang Niu, Linas Mazutis, Xueqiao Jiang, Xueting Wang, Fuying Gao, Matthew B Brendel, Maria A Telpoukhovskaia, Tara E Tracy, Georgia Frost, Yungui Zhou, Yaqiao Li, Yue Qiu, Zuolin Cheng, Guoqiang Yu, John A Hardy, Giovanni Coppola, Fei Wang, Michael A DeTure, Bin Zhang, Lei Xie, John Q Trojanowski, Virginia M Y Lee, Shiaoching Gong, Subhash C Sinha, Gourisankar Ghosh, Wenjie Luo, Li Gan
AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation. Science translational medicine 13 (622) (2021)
Hansaim Lim, Di He, Yue Qiu, Patrycja Krawczuk, Xiaoru Sun, Lei Xie
Rational discovery of dual-indication multi-target PDE/Kinase inhibitor for precision anti-cancer therapy using structural systems pharmacology. PLoS computational biology 15 (6) (2019)
Li Xie, Lei Xie
Pathway-Centric Structure-Based Multi-Target Compound Screening for Anti-Virulence Drug Repurposing. International journal of molecular sciences 20 (14) (2019)
Aleksandar Poleksic, Lei Xie
Database of adverse events associated with drugs and drug combinations. Scientific reports 9 (1) (2019)