Libin Xu

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 56

Top Venues

bioRxiv : the preprint server for biology

Environmental science & technology

Drug metabolism and disposition: the biological fate of chemicals

The Journal of infectious diseases

University of Washington

University of Illinois at Chicago (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Washington Dec 01 2014

United States

Assistant Professor :: Medicinal Chemistry

Vanderbilt University Jan 01 2013 - Nov 30 2014

United States

Research Associate Professor :: Chemistry

Vanderbilt University Oct 01 2010 - Dec 31 2012

United States

Research Assistant Professor :: Chemistry

Vanderbilt University Aug 16 2009 - Sep 30 2010

United States

Senior Research Associate :: Chemistry

Vanderbilt University Aug 01 2007 - Aug 15 2009

United States

Research Associate :: Chemistry

Education History

University of Illinois at Chicago Aug 05 2002 - Jul 22 2007

United States

PHD :: Chemistry

Nankai University Sep 01 1998 - Jun 15 2002

China

BSC :: Chemistry

Publications

Letícia Salvador Vieira, Ryan P Seguin, Libin Xu, Joanne Wang
Interaction and Transport of Benzalkonium Chlorides by the Organic Cation and Multidrug and Toxin Extrusion Transporters. Drug metabolism and disposition: the biological fate of chemicals 52 (4) (2024)
Ryan Nguyen, Ryan P Seguin, Dylan H Ross, Pengyu Chen, Sean Richardson, Jennifer Liem, Yvonne S Lin, Libin Xu
Development and Application of a Multidimensional Database for the Detection of Quaternary Ammonium Compounds and Their Phase I Hepatic Metabolites in Humans. Environmental science & technology 58 (14) (2024)
Djuro Raskovic, Gloria Alvarado, Kelly M Hines, Libin Xu, Craig Gatto, Brian J Wilkinson, Antje Pokorny
Growth of Staphylococcus aureus in the presence of oleic acid shifts the glycolipid fatty acid profile and increases resistance to antimicrobial peptides. bioRxiv : the preprint server for biology (2024)
William R Miller, April Nguyen, Kavindra V Singh, Samie Rizvi, Ayesha Khan, Sam G Erickson, Stephanie L Egge, Melissa Cruz, An Q Dinh, Lorena Diaz, Philip C Thornton, Rutan Zhang, Libin Xu, Danielle A Garsin, Yousif Shamoo, Cesar A Arias
Membrane Lipids Augment Cell Envelope Stress Signaling via the MadRS System to Defend Against Antimicrobial Peptides and Antibiotics in Enterococcus faecalis. The Journal of infectious diseases (2024)
Ryan Nguyen, Ryan P Seguin, Dylan H Ross, Pengyu Chen, Sean Richardson, Jennifer Liem, Yvonne S Lin, Libin Xu
Development and Application of a Multidimensional Database for the Detection of Quaternary Ammonium Compounds and Their Phase I Hepatic Metabolites in Humans. Environmental science & technology 58 (14) (2024)
Ryan Nguyen, Ryan P Seguin, Dylan H Ross, Pengyu Chen, Sean Richardson, Jennifer Liem, Yvonne S Lin, Libin Xu
Development and Application of a Multidimensional Database for the Detection of Quaternary Ammonium Compounds and Their Phase I Hepatic Metabolites in Humans. Environmental science & technology (2024)
Heidi M J Weakly, Kent J Wilson, Gunnar J Goetz, Emily L Pruitt, Amy Li, Libin Xu, Sarah L Keller
Several common methods of making vesicles (except an emulsion method) capture intended lipid ratios. bioRxiv : the preprint server for biology (2024)
William R Miller, April Nguyen, Kavindra V Singh, Samie Rizvi, Ayesha Khan, Sam G Erickson, Stephanie L Egge, Melissa Cruz, An Q Dinh, Lorena Diaz, Philip C Thornton, Rutan Zhang, Libin Xu, Danielle A Garsin, Yousif Shamoo, Cesar A Arias
Membrane Lipids Augment Cell Envelope Stress Signaling via the MadRS System to Defend Against Antimicrobial Peptides and Antibiotics in Enterococcus faecalis. The Journal of infectious diseases (2024)
William R Miller, April Nguyen, Kavindra V Singh, Samie Rizvi, Ayesha Khan, Sam G Erickson, Stephanie L Egge, Melissa Cruz, An Q Dinh, Lorena Diaz, Philip C Thornton, Rutan Zhang, Libin Xu, Danielle A Garsin, Yousif Shamoo, Cesar A Arias
Membrane Lipids Augment Cell Envelope Stress Signaling via the MadRS System to Defend Against Antimicrobial Peptides and Antibiotics in Enterococcus faecalis. The Journal of infectious diseases (2024)
Heidi M J Weakly, Kent J Wilson, Gunnar J Goetz, Emily L Pruitt, Amy Li, Libin Xu, Sarah L Keller
Several common methods of making vesicles (except an emulsion method) capture intended lipid ratios. bioRxiv : the preprint server for biology (2024)
Vanessa A Lopez, Joe L Lim, Ryan P Seguin, Joseph L Dempsey, Gabrielle Kunzman, Julia Y Cui, Libin Xu
Oral Exposure to Benzalkonium Chlorides in Male and Female Mice Reveals Sex-Dependent Alteration of the Gut Microbiome and Bile Acid Profile. bioRxiv : the preprint server for biology (2024)
Letícia Salvador Vieira, Ryan P Seguin, Libin Xu, Joanne Wang
Interaction and Transport of Benzalkonium Chlorides by the Organic Cation and Multidrug and Toxin Extrusion Transporters. Drug metabolism and disposition: the biological fate of chemicals 52 (4) (2024)
Letícia S Vieira, Ryan P Seguin, Libin Xu, Joanne Wang
Interaction and Transport of Benzalkonium Chlorides (BACs) by the Organic Cation and Multidrug and Toxin Extrusion Transporters . Drug metabolism and disposition: the biological fate of chemicals (2024)
William R Miller, April Nguyen, Kavindra V Singh, Samie Rizvi, Ayesha Khan, Sam G Erickson, Stephanie L Egge, Melissa Cruz, An Q Dinh, Lorena Diaz, Philip C Thornton, Rutan Zhang, Libin Xu, Danielle A Garsin, Yousif Shamoo, Cesar A Arias
Membrane Lipids Augment Cell Envelope Stress Signaling via the MadRS System to Defend Against Antimicrobial Peptides and Antibiotics in Enterococcus faecalis. The Journal of infectious diseases (2024)
Ryan Nguyen, Ryan P Seguin, Dylan H Ross, Pengyu Chen, Sean Richardson, Jennifer Liem, Yvonne S Lin, Libin Xu
Development and Application of a Multidimensional Database for the Detection of Quaternary Ammonium Compounds and Their Phase I Hepatic Metabolites in Humans. Environmental science & technology 58 (14) (2024)
Letícia Salvador Vieira, Ryan P Seguin, Libin Xu, Joanne Wang
Interaction and Transport of Benzalkonium Chlorides by the Organic Cation and Multidrug and Toxin Extrusion Transporters. Drug metabolism and disposition: the biological fate of chemicals 52 (4) (2024)
Ryan Nguyen, Ryan P Seguin, Dylan H Ross, Pengyu Chen, Sean Richardson, Jennifer Liem, Yvonne S Lin, Libin Xu
Development and Application of a Multidimensional Database for the Detection of Quaternary Ammonium Compounds and Their Phase I Hepatic Metabolites in Humans. Environmental science & technology 58 (14) (2024)
Letícia Salvador Vieira, Ryan P Seguin, Libin Xu, Joanne Wang
Interaction and Transport of Benzalkonium Chlorides by the Organic Cation and Multidrug and Toxin Extrusion Transporters. Drug metabolism and disposition: the biological fate of chemicals 52 (4) (2024)
William R Miller, April Nguyen, Kavindra V Singh, Samie Rizvi, Ayesha Khan, Sam G Erickson, Stephanie L Egge, Melissa Cruz, An Q Dinh, Lorena Diaz, Philip C Thornton, Rutan Zhang, Libin Xu, Danielle A Garsin, Yousif Shamoo, Cesar A Arias
Membrane Lipids Augment Cell Envelope Stress Signaling via the MadRS System to Defend Against Antimicrobial Peptides and Antibiotics in Enterococcus faecalis. The Journal of infectious diseases (2024)
Djuro Raskovic, Gloria Alvarado, Kelly M Hines, Libin Xu, Craig Gatto, Brian J Wilkinson, Antje Pokorny
Growth of Staphylococcus aureus in the presence of oleic acid shifts the glycolipid fatty acid profile and increases resistance to antimicrobial peptides. bioRxiv : the preprint server for biology (2024)
Letícia Salvador Vieira, Ryan P Seguin, Libin Xu, Joanne Wang
Interaction and Transport of Benzalkonium Chlorides by the Organic Cation and Multidrug and Toxin Extrusion Transporters. Drug metabolism and disposition: the biological fate of chemicals 52 (4) (2024)
Letícia Salvador Vieira, Ryan P Seguin, Libin Xu, Joanne Wang
Interaction and Transport of Benzalkonium Chlorides by the Organic Cation and Multidrug and Toxin Extrusion Transporters. Drug metabolism and disposition: the biological fate of chemicals 52 (4) (2024)
Ryan Nguyen, Ryan P Seguin, Dylan H Ross, Pengyu Chen, Sean Richardson, Jennifer Liem, Yvonne S Lin, Libin Xu
Development and Application of a Multidimensional Database for the Detection of Quaternary Ammonium Compounds and Their Phase I Hepatic Metabolites in Humans. Environmental science & technology 58 (14) (2024)
William A Arnold, Arlene Blum, Jennifer Branyan, Thomas A Bruton, Courtney C Carignan, Gino Cortopassi, Sandipan Datta, Jamie DeWitt, Anne-Cooper Doherty, Rolf U Halden, Homero Harari, Erica M Hartmann, Terry C Hrubec, Shoba Iyer, Carol F Kwiatkowski, Jonas LaPier, Dingsheng Li, Li Li, Jorge G Muñiz Ortiz, Amina Salamova, Ted Schettler, Ryan P Seguin, Anna Soehl, Rebecca Sutton, Libin Xu, Guomao Zheng
Quaternary Ammonium Compounds: A Chemical Class of Emerging Concern. Environmental science & technology (2023)
Amy Li, Hideaki Tomita, Libin Xu
Temporal gene expression changes and affected pathways in neurodevelopment of a mouse model of Smith-Lemli-Opitz syndrome. bioRxiv : the preprint server for biology (2023)
April H Nguyen, Truc T Tran, Diana Panesso, Kara Hood, Vinathi Polamraju, Rutan Zhang, Ayesha Khan, William R Miller, Eugenia Mileykovskaya, Yousif Shamoo, Libin Xu, Heidi Vitrac, Cesar A Arias
Molecular Basis of Cell Membrane Adaptation in Daptomycin-Resistant Enterococcus faecalis . bioRxiv : the preprint server for biology (2023)
Quynh Do, Rutan Zhang, Gavin Hooper, Libin Xu
Differential Contributions of Distinct Free Radical Peroxidation Mechanisms to the Induction of Ferroptosis. JACS Au 3 (4) (2023)
Quynh Do, Rutan Zhang, Gavin Hooper, Libin Xu
Differential Contributions of Distinct Free Radical Peroxidation Mechanisms to the Induction of Ferroptosis. JACS Au 3 (4) (2023)
Amy Li, Libin Xu
MALDI-IM-MS Imaging of Brain Sterols and Lipids in a Mouse Model of Smith-Lemli-Opitz Syndrome. bioRxiv : the preprint server for biology (2023)
Emily L Pruitt, Rutan Zhang, Dylan H Ross, Nathaniel K Ashford, Xi Chen, Francis Alonzo, Matthew F Bush, Brian J Werth, Libin Xu
Elucidating the Impact of Bacterial Lipases, Human Serum Albumin, and FASII Inhibition on the Utilization of Exogenous Fatty Acids by Staphylococcus aureus . bioRxiv : the preprint server for biology (2023)
Noelle Reimers, Quynh Do, Rutan Zhang, Angela Guo, Ryan Ostrander, Alyson Shoji, Chau Vuong, Libin Xu
Tracking the Metabolic Fate of Exogenous Arachidonic Acid in Ferroptosis Using Dual-Isotope Labeling Lipidomics. Journal of the American Society for Mass Spectrometry (2023)
William A Arnold, Arlene Blum, Jennifer Branyan, Thomas A Bruton, Courtney C Carignan, Gino Cortopassi, Sandipan Datta, Jamie DeWitt, Anne-Cooper Doherty, Rolf U Halden, Homero Harari, Erica M Hartmann, Terry C Hrubec, Shoba Iyer, Carol F Kwiatkowski, Jonas LaPier, Dingsheng Li, Li Li, Jorge G Muñiz Ortiz, Amina Salamova, Ted Schettler, Ryan P Seguin, Anna Soehl, Rebecca Sutton, Libin Xu, Guomao Zheng
Quaternary Ammonium Compounds: A Chemical Class of Emerging Concern. Environmental science & technology 57 (20) (2023)
William R Miller, April Nguyen, Kavindra V Singh, Samie Rizvi, Ayesha Khan, Sam G Erickson, Stephanie L Egge, Melissa Cruz, An Q Dinh, Lorena Diaz, Rutan Zhang, Libin Xu, Danielle A Garsin, Yousif Shamoo, Cesar A Arias
Membrane Lipids Augment Cell Envelope Stress Signaling and Resistance to Antibiotics and Antimicrobial Peptides in Enterococcus faecalis . bioRxiv : the preprint server for biology (2023)
Emily L Pruitt, Rutan Zhang, Dylan H Ross, Nathaniel K Ashford, Xi Chen, Francis Alonzo, Matthew F Bush, Brian J Werth, Libin Xu
Elucidating the impact of bacterial lipases, human serum albumin, and FASII inhibition on the utilization of exogenous fatty acids by Staphylococcus aureus . mSphere (2023)
William A Arnold, Arlene Blum, Jennifer Branyan, Thomas A Bruton, Courtney C Carignan, Gino Cortopassi, Sandipan Datta, Jamie DeWitt, Anne-Cooper Doherty, Rolf U Halden, Homero Harari, Erica M Hartmann, Terry C Hrubec, Shoba Iyer, Carol F Kwiatkowski, Jonas LaPier, Dingsheng Li, Li Li, Jorge G Muñiz Ortiz, Amina Salamova, Ted Schettler, Ryan P Seguin, Anna Soehl, Rebecca Sutton, Libin Xu, Guomao Zheng
Quaternary Ammonium Compounds: A Chemical Class of Emerging Concern. Environmental science & technology (2023)
Vikas Daggubati, Akshara Vykunta, Abrar Choudhury, Zulekha Qadeer, Kanish Mirchia, Olivier Saulnier, Naomi Zakimi, Kelly Hines, Michael D Paul, Linyu Wang, Natalia Jura, Libin Xu, Jeremy F Reiter, Michael D Taylor, William Weiss, David R Raleigh
Hedgehog target genes regulate lipid metabolism to drive basal cell carcinoma and medulloblastoma. Research square (2023)
Dylan H Ross, Ryan P Seguin, Allison M Krinsky, Libin Xu
High-Throughput Measurement and Machine Learning-Based Prediction of Collision Cross Sections for Drugs and Drug Metabolites. Journal of the American Society for Mass Spectrometry 33 (6) (2022)
Adeline Supandy, Heer H Mehta, Truc T Tran, William R Miller, Rutan Zhang, Libin Xu, Cesar A Arias, Yousif Shamoo
Evolution of Enterococcus faecium in Response to a Combination of Daptomycin and Fosfomycin Reveals Distinct and Diverse Adaptive Strategies. Antimicrobial agents and chemotherapy 66 (6) (2022)
Amy Li, Kelly M Hines, Dylan H Ross, James W MacDonald, Libin Xu
Temporal changes in the brain lipidome during neurodevelopment of Smith-Lemli-Opitz syndrome mice. The Analyst 147 (8) (2022)
See-Yeun Ting, Kaitlyn D LaCourse, Hannah E Ledvina, Rutan Zhang, Matthew C Radey, Hemantha D Kulasekara, Rahul Somavanshi, Savannah K Bertolli, Larry A Gallagher, Jennifer Kim, Kelsi M Penewit, Stephen J Salipante, Libin Xu, S Brook Peterson, Joseph D Mougous
Discovery of coordinately regulated pathways that provide innate protection against interbacterial antagonism. eLife 11 (2022)
Hideaki Tomita, Kelly M Hines, Josi M Herron, Amy Li, David W Baggett, Libin Xu
7-Dehydrocholesterol-derived oxysterols cause neurogenic defects in Smith-Lemli-Opitz syndrome. eLife 11 (2022)
Megan Lo, Amnon Sharir, Michael D Paul, Hayarpi Torosyan, Christopher Agnew, Amy Li, Cynthia Neben, Pauline Marangoni, Libin Xu, David R Raleigh, Natalia Jura, Ophir D Klein
CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids. Nature communications 13 (1) (2022)
Josi M Herron, Hideaki Tomita, Collin C White, Terrance J Kavanagh, Libin Xu
Benzalkonium Chloride Disinfectants Induce Apoptosis, Inhibit Proliferation, and Activate the Integrated Stress Response in a 3-D in Vitro Model of Neurodevelopment. Chemical research in toxicology 34 (5) (2021)
Bruce A Pfeffer, Libin Xu, Steven J Fliesler
Transcriptomic Changes Associated with Loss of Cell Viability Induced by Oxysterol Treatment of a Retinal Photoreceptor-Derived Cell Line: An In Vitro Model of Smith-Lemli-Opitz Syndrome. International journal of molecular sciences 22 (5) (2021)
Dylan H Ross, Jang Ho Cho, Libin Xu
Breaking Down Structural Diversity for Comprehensive Prediction of Ion-Neutral Collision Cross Sections. Analytical chemistry 92 (6) (2020)
Dylan H Ross, Jang Ho Cho, Rutan Zhang, Kelly M Hines, Libin Xu
LiPydomics: A Python Package for Comprehensive Prediction of Lipid Collision Cross Sections and Retention Times and Analysis of Ion Mobility-Mass Spectrometry-Based Lipidomics Data. Analytical chemistry 92 (22) (2020)
Radha M Golla, Biswajit Mishra, Xiangli Dang, Jayaram Lakshmaiah Narayana, Amy Li, Libin Xu, Guangshun Wang
Resistome of Staphylococcus aureus in Response to Human Cathelicidin LL-37 and Its Engineered Antimicrobial Peptides. ACS infectious diseases 6 (7) (2020)
Kelly M Hines, Gloria Alvarado, Xi Chen, Craig Gatto, Antje Pokorny, Francis Alonzo, Brian J Wilkinson, Libin Xu
Lipidomic and Ultrastructural Characterization of the Cell Envelope of Staphylococcus aureus Grown in the Presence of Human Serum. mSphere 5 (3) (2020)
Ned A Porter, Libin Xu, Derek A Pratt
Reactive Sterol Electrophiles: Mechanisms of Formation and Reactions with Proteins and Amino Acid Nucleophiles. Chemistry (Basel, Switzerland) 2 (2) (2020)
Quynh Do, David D Lee, Andrew N Dinh, Ryan P Seguin, Rutan Zhang, Libin Xu
Development and Application of a Peroxyl Radical Clock Approach for Measuring Both Hydrogen-Atom Transfer and Peroxyl Radical Addition Rate Constants. The Journal of organic chemistry 86 (1) (2020)
Ryan P Seguin, Josi M Herron, Vanessa A Lopez, Joseph L Dempsey, Libin Xu
Metabolism of Benzalkonium Chlorides by Human Hepatic Cytochromes P450. Chemical research in toxicology 32 (12) (2019)
Aurore Fleurie, Abdelrahim Zoued, Laura Alvarez, Kelly M Hines, Felipe Cava, Libin Xu, Brigid M Davis, Matthew K Waldor
A Vibrio cholerae BolA-Like Protein Is Required for Proper Cell Shape and Cell Envelope Integrity. mBio 10 (4) (2019)
Dylan H Ross, Ryan P Seguin, Libin Xu
Characterization of the Impact of Drug Metabolism on the Gas-Phase Structures of Drugs Using Ion Mobility-Mass Spectrometry. Analytical chemistry 91 (22) (2019)
Steven J Fliesler, Libin Xu
Oxysterols and Retinal Degeneration in a Rat Model of Smith-Lemli-Opitz Syndrome: Implications for an Improved Therapeutic Intervention. Molecules (Basel, Switzerland) 23 (10) (2018)
Kelly M Hines, Adam Waalkes, Kelsi Penewit, Elizabeth A Holmes, Stephen J Salipante, Brian J Werth, Libin Xu
Characterization of the Mechanisms of Daptomycin Resistance among Gram-Positive Bacterial Pathogens by Multidimensional Lipidomics. mSphere 2 (6) (2017)
Kelly M Hines, Dylan H Ross, Kimberly L Davidson, Matthew F Bush, Libin Xu
Large-Scale Structural Characterization of Drug and Drug-Like Compounds by High-Throughput Ion Mobility-Mass Spectrometry. Analytical chemistry 89 (17) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Libin Xu