Luciano Cascione (L Cascione)

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 31

Top Venues

British journal of haematology

Molecular cancer therapeutics

Cancers

Clinical cancer research : an official journal of the American Association for Cancer Research

Institute of Oncology Research

University of Catania (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Institute of Oncology Research Jan 01 2018

Switzerland

Head of Bioinformatics Core Unit

Institute of Oncology Research Mar 19 2013 - Jan 01 2018

Switzerland

PostDoc- Junior Bioinformatician :: Lymphoma Research Group

Università degli Studi di Catania Oct 01 2009 - Oct 01 2012

Italy

Phd Student :: Facolta' di Medicina e Chirurgia

Education History

University of Catania Sep 01 2009 - Oct 01 2012

Italy

PHD

University of Catania Sep 01 2006 - Jul 01 2009

Italy

MSC :: Mathematics and Computer Science

University of Catania Sep 01 2002 - Apr 01 2006

Italy

BSC :: Mathematics and Informatics

Publications

Francesca Zammarchi, Karin E Havenith, Nikoleta Sachini, Narinder Janghra, Simon Chivers, Esohe Idusogie, Eugenio Gaudio, Chiara Tarantelli, Francois Bertelli, Kathleen Santos, Peter Tyrer, Simon Corbett, Filippo Spriano, Gaetanina Golino, Luciano Cascione, Francesco Bertoni, John A Hartley, Patrick H van Berkel
ADCT-602, a novel PBD dimer-containing antibody-drug conjugate for treating CD22-positive hematological malignancies. Molecular cancer therapeutics (2024)
Francesca Zammarchi, Karin E Havenith, Nikoleta Sachini, Narinder Janghra, Simon Chivers, Esohe Idusogie, Eugenio Gaudio, Chiara Tarantelli, Francois Bertelli, Kathleen Santos, Peter Tyrer, Simon Corbett, Filippo Spriano, Gaetanina Golino, Luciano Cascione, Francesco Bertoni, John A Hartley, Patrick H van Berkel
ADCT-602, a Novel PBD Dimer-containing Antibody-Drug Conjugate for Treating CD22-positive Hematologic Malignancies. Molecular cancer therapeutics 23 (4) (2024)
Somaieh Hedayat, Luciano Cascione, David Cunningham, Heinz-Josef Lenz, Andrea Lampis, Jens Claus Hahne, Nina Tunariu, Sung Pil Hong, Silvia Marchetti, Khurum Khan, Elisa Fontana, Valentina Angerilli, Mia Delrieux, Daniel Nava Rodrigues, Letizia Procaccio, Sheela Rao, David Watkins, Naureen Starling, Ian Chau, Chiara Braconi, Nicos Fotiadis, Ruwaida Begum, Naomi Jayne Guppy, Louise Howell, Melanie Valenti, Scott Cribbes, Bernadett Kolozsvari, Vladimir Kirkin, Sara Lonardi, Michele Ghidini, Rodolfo Passalacqua, Raghad Elghadi, Luca Magnani, David James Pinato, Federica Di Maggio, Filippo Ghelardi, Elisa Sottotetti, Guglielmo Vetere, Paolo Ciracì, Georgios Vlachogiannis, Filippo Pietrantonio, Chiara Cremolini, Alessio Cortellini, Fotios Loupakis, Angelo Paolo Dei Tos, Nicola Valeri
Circulating microRNA Analysis in a Prospective Co-clinical Trial Identifies MIR652-3p as a Response Biomarker and Driver of Regorafenib Resistance Mechanisms in Colorectal Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (10) (2024)
Somaieh Hedayat, Luciano Cascione, David Cunningham, Heinz-Josef Lenz, Andrea Lampis, Jens Claus Hahne, Nina Tunariu, Sung Pil Hong, Silvia Marchetti, Khurum Khan, Elisa Fontana, Valentina Angerilli, Mia Delrieux, Daniel Nava Rodrigues, Letizia Procaccio, Sheela Rao, David Watkins, Naureen Starling, Ian Chau, Chiara Braconi, Nicos Fotiadis, Ruwaida Begum, Naomi Jayne Guppy, Louise Howell, Melanie Valenti, Scott Cribbes, Bernadett Kolozsvari, Vladimir Kirkin, Sara Lonardi, Michele Ghidini, Rodolfo Passalacqua, Raghad Elghadi, Luca Magnani, David James Pinato, Federica Di Maggio, Filippo Ghelardi, Elisa Sottotetti, Guglielmo Vetere, Paolo Ciracì, Georgios Vlachogiannis, Filippo Pietrantonio, Chiara Cremolini, Alessio Cortellini, Fotios Loupakis, Angelo Paolo Dei Tos, Nicola Valeri
Circulating microRNA Analysis in a Prospective Co-clinical Trial Identifies MIR652-3p as a Response Biomarker and Driver of Regorafenib Resistance Mechanisms in Colorectal Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (10) (2024)
Somaieh Hedayat, Luciano Cascione, David Cunningham, Heinz-Josef Lenz, Andrea Lampis, Jens Claus Hahne, Nina Tunariu, Sung Pil Hong, Silvia Marchetti, Khurum Khan, Elisa Fontana, Valentina Angerilli, Mia Delrieux, Daniel Nava Rodrigues, Letizia Procaccio, Sheela Rao, David Watkins, Naureen Starling, Ian Chau, Chiara Braconi, Nicos Fotiadis, Ruwaida Begum, Naomi Jayne Guppy, Louise Howell, Melanie Valenti, Scott Cribbes, Bernadett Kolozsvari, Vladimir Kirkin, Sara Lonardi, Michele Ghidini, Rodolfo Passalacqua, Raghad Elghadi, Luca Magnani, David James Pinato, Federica Di Maggio, Filippo Ghelardi, Elisa Sottotetti, Guglielmo Vetere, Paolo Ciracì, Georgios Vlachogiannis, Filippo Pietrantonio, Chiara Cremolini, Alessio Cortellini, Fotios Loupakis, Angelo Paolo Dei Tos, Nicola Valeri
Circulating microRNA analysis in a prospective co-clinical trial identifies MIR652-3p as a response biomarker and driver of regorafenib resistance mechanisms in colorectal cancer. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Francesca Zammarchi, Karin E Havenith, Nikoleta Sachini, Narinder Janghra, Simon Chivers, Esohe Idusogie, Eugenio Gaudio, Chiara Tarantelli, Francois Bertelli, Kathleen Santos, Peter Tyrer, Simon Corbett, Filippo Spriano, Gaetanina Golino, Luciano Cascione, Francesco Bertoni, John A Hartley, Patrick H van Berkel
ADCT-602, a Novel PBD Dimer-containing Antibody-Drug Conjugate for Treating CD22-positive Hematologic Malignancies. Molecular cancer therapeutics 23 (4) (2024)
Alberto J Arribas, Sara Napoli, Luciano Cascione, Laura Barnabei, Giulio Sartori, Eleonora Cannas, Eugenio Gaudio, Chiara Tarantelli, Afua Adjeiwaa Mensah, Filippo Spriano, Antonella Zucchetto, Francesca Maria Rossi, Andrea Rinaldi, Manuel Castro de Moura, Sandra Jovic, Roberta Bordone Pittau, Anastasios Stathis, Georg Stussi, Valter Gattei, Jennifer R Brown, Manel Esteller, Emanuele Zucca, Davide Rossi, Francesco Bertoni
ERBB4-Mediated Signaling Is a Mediator of Resistance to PI3K and BTK Inhibitors in B-cell Lymphoid Neoplasms. Molecular cancer therapeutics (2023)
Alberto J Arribas, Sara Napoli, Luciano Cascione, Laura Barnabei, Giulio Sartori, Eleonora Cannas, Eugenio Gaudio, Chiara Tarantelli, Afua Adjeiwaa Mensah, Filippo Spriano, Antonella Zucchetto, Francesca Maria Rossi, Andrea Rinaldi, Manuel Castro de Moura, Sandra Jovic, Roberta Bordone Pittau, Anastasios Stathis, Georg Stussi, Valter Gattei, Jennifer R Brown, Manel Esteller, Emanuele Zucca, Davide Rossi, Francesco Bertoni
ERBB4-mediated signaling is a mediator of resistance to BTK and PI3K inhibitors in B cell lymphoid neoplasms. bioRxiv : the preprint server for biology (2023)
Zoe Johnson, Chiara Tarantelli, Elisa Civanelli, Luciano Cascione, Filippo Spriano, Amy Fraser, Pritom Shah, Tyzoon Nomanbhoy, Sara Napoli, Andrea Rinaldi, Karolina Niewola-Staszkowska, Michael Lahn, Dominique Perrin, Mathias Wenes, Denis Migliorini, Francesco Bertoni, Lars van der Veen, Giusy Di Conza
IOA-244 is a Non-ATP-competitive, Highly Selective, Tolerable PI3K Delta Inhibitor That Targets Solid Tumors and Breaks Immune Tolerance. Cancer research communications 3 (4) (2023)
Alberto J Arribas, Eugenio Gaudio, Sara Napoli, Charles Jean Yvon Herbaux, Chiara Tarantelli, Roberta Pittau Bordone, Luciano Cascione, Nicolas Munz, Luca Aresu, Jacopo Sgrignani, Andrea Rinaldi, Ivo Kwee, Davide Rossi, Andrea Cavalli, Emanuele Zucca, Georg Stussi, Anastasios Stathis, Callum Sloss, Matthew S Davids, Francesco Bertoni
PI3Kδ activation, IL6 over-expression, and CD37 loss cause resistance to the targeting of CD37-positive lymphomas with the antibody-drug conjugate naratuximab emtansine. bioRxiv : the preprint server for biology (2023)
Lodovico Terzi di Bergamo, Francesca Guidetti, Davide Rossi, Francesco Bertoni, Luciano Cascione
HTGQC and shinyHTGQC: an R package and shinyR application for quality controls of HTG EDGE-seq protocols. GigaByte (Hong Kong, China) 2022 (2022)
Sofia Genta, Guido Ghilardi, Luciano Cascione, Darius Juskevicius, Alexandar Tzankov, Sämi Schär, Lisa Milan, Maria Cristina Pirosa, Fabiana Esposito, Teresa Ruberto, Luca M Giovanella, Stefanie Hayoz, Christoph Mamot, Stefan Dirnhofer, Emanuele Zucca, Luca Ceriani
Integration of Baseline Metabolic Parameters and Mutational Profiles Predicts Long-Term Response to First-Line Therapy in DLBCL Patients: A Post Hoc Analysis of the SAKK38/07 Study. Cancers 14 (4) (2022)
Tommaso Virgilio, Joy Bordini, Luciano Cascione, Giulio Sartori, Irene Latino, Daniel Molina Romero, Cristina Leoni, Murodzhon Akhmedov, Andrea Rinaldi, Alberto J Arribas, Diego Morone, Seyed Morteza Seyed Jafari, Marina Bersudsky, Aner Ottolenghi, Ivo Kwee, Anna Maria Chiaravalli, Fausto Sessa, Robert E Hunger, Antonino Bruno, Lorenzo Mortara, Elena Voronov, Silvia Monticelli, Ron N Apte, Francesco Bertoni, Santiago Fernandez Gonzalez
Subcapsular Sinus Macrophages Promote Melanoma Metastasis to the Sentinel Lymph Nodes via an IL1α-STAT3 Axis. Cancer immunology research 10 (12) (2022)
Lodovico Terzi di Bergamo, Francesca Guidetti, Davide Rossi, Francesco Bertoni, Luciano Cascione
HTGQC and shinyHTGQC: an R package and shinyR application for quality controls of HTG EDGE-seq protocols. GigaByte (Hong Kong, China) 2022 (2022)
Chiara Tarantelli, Eleonora Cannas, Hillarie Ekeh, Carmelo Moscatello, Eugenio Gaudio, Luciano Cascione, Sara Napoli, Cesare Rech, Andrea Testa, Chiara Maniaci, Andrea Rinaldi, Emanuele Zucca, Anastasios Stathis, Alessio Ciulli, Francesco Bertoni
The bromodomain and extra-terminal domain degrader MZ1 exhibits preclinical anti-tumoral activity in diffuse large B-cell lymphoma of the activated B cell-like type. Exploration of targeted anti-tumor therapy 2 (6) (2021)
Afua Adjeiwaa Mensah, Filippo Spriano, Giulio Sartori, Valdemar Priebe, Luciano Cascione, Eugenio Gaudio, Chiara Tarantelli, Elisa Civanelli, Luca Aresu, Andrea Rinaldi, Giovanna Damia, Emanuela Lovati, Emanuele Zucca, Anastasios Stathis, Claudio Pietra, Francesco Bertoni
Study of the antilymphoma activity of pracinostat reveals different sensitivities of DLBCL cells to HDAC inhibitors. Blood advances 5 (10) (2021)
Nicolas Munz, Luciano Cascione, Luca Parmigiani, Chiara Tarantelli, Andrea Rinaldi, Natasa Cmiljanovic, Vladimir Cmiljanovic, Rosalba Giugno, Francesco Bertoni, Sara Napoli
Exon-Intron Differential Analysis Reveals the Role of Competing Endogenous RNAs in Post-Transcriptional Regulation of Translation. Non-coding RNA 7 (2) (2021)
Ferdinando Bonfiglio, Alessio Bruscaggin, Francesca Guidetti, Lodovico Terzi di Bergamo, Martin Richard Faderl, Valeria Spina, Adalgisa Condoluci, Luisella Bonomini, Gabriela Forestieri, Ricardo Koch, Deborah Piffaretti, Katia Pini, Maria Cristina Pirosa, Micol Giulia Cittone, Alberto J Arribas, Marco Lucioni, Guido Ghilardi, Wei Wu, Luca Arcaini, Maria Joao Baptista, Gabriela Bastidas, Sílvia Beà, Renzo Boldorini, Alessandro Broccoli, Marco Matteo Bühler, Vincenzo Canzonieri, Luciano Cascione, Luca Ceriani, Sergio B Cogliatti, Paolo Corradini, Enrico Derenzini, Liliana Devizzi, Sascha Dietrich, Angela Rita Elia, Fabio Facchetti, Gianluca Gaidano, Juan Fernando García, Bernhard Gerber, Paolo Ghia, Maria Gomes da Silva, Giuseppe Gritti, Anna Guidetti, Felicitas Hitz, Giorgio Ga Inghirami, Marco Ladetto, Armando López-Guillermo, Elisa Lucchini, Antonino Maiorana, Roberto Marasca, Estella Matutes, Véronique Meignin, Michele Merli, Alden A Moccia, Manuela Mollejo, Carlos Montalban, Urban Novak, David Graham Oscier, Francesco Passamonti, Francesco A Piazza, Stefano Pizzolitto, Alessandro Rambaldi, Elena Sabattini, Gilles Andre Salles, Elisa Santambrogio, Lydia Scarfo, Anastasios Stathis, Georg Stussi, Julia Turbiner Geyer, Gustavo Tapia, Corrado Tarella, Catherine Thieblemont, Thomas Tousseyn, Alessandra Tucci, Giorgio Vanini, Carlo Visco, Umberto Vitolo, Renata Walewska, Francesco Zaja, Thorsten Zenz, Pier Luigi Luigi Zinzani, Hossein Khiabanian, Arianna Calcinotto, Francesco Bertoni, Govind Bhagat, Elias Campo, Laurence de Leval, Stefan Dirnhofer, Stefano A Pileri, Miguel A Piris, Alexandra Traverse-Glehen, Alexandar Tzankov, Marco Paulli, Maurilio Ponzoni, Luca Mazzucchelli, Franco Cavalli, Emanuele Zucca, Davide Rossi
Genetic and Phenotypic Attributes of Splenic Marginal Zone Lymphoma. Blood (2021)
Valdemar Priebe, Giulio Sartori, Sara Napoli, Elaine Yee Lin Chung, Luciano Cascione, Ivo Kwee, Alberto Jesus Arribas, Afua Adjeiwaa Mensah, Andrea Rinaldi, Maurilio Ponzoni, Emanuele Zucca, Davide Rossi, Dimitar G Efremov, Georg Lenz, Margot Thome, Francesco Bertoni
Role of ETS1 in the Transcriptional Network of Diffuse Large B Cell Lymphoma of the Activated B Cell-Like Type. Cancers 12 (7) (2020)
Andrea Unzue, Claudia Jessen-Trefzer, Dimitrios Spiliotopoulos, Eugenio Gaudio, Chiara Tarantelli, Jing Dong, Hongtao Zhao, Johanna Pachmayr, Stefan Zahler, Elena Bernasconi, Giulio Sartori, Luciano Cascione, Francesco Bertoni, Paweł Śledź, Amedeo Caflisch, Cristina Nevado
Understanding the mechanism of action of pyrrolo[3,2-b]quinoxaline-derivatives as kinase inhibitors. RSC medicinal chemistry 11 (6) (2020)
Emanuele Zucca, Luciano Cascione, Teresa Ruberto, Davide Facchinelli, Sämi Schär, Stefanie Hayoz, Stefan Dirnhofer, Luca M Giovanella, Mario Bargetzi, Christoph Mamot, Luca Ceriani
Prognostic models integrating quantitative parameters from baseline and interim positron emission computed tomography in patients with diffuse large B-cell lymphoma: post-hoc analysis from the SAKK38/07 clinical trial. Hematological oncology 38 (5) (2020)
Alberto J Arribas, Andrea Rinaldi, Giorgia Chiodin, Ivo Kwee, Afua Adjeiwaa Mensah, Luciano Cascione, Davide Rossi, Meena Kanduri, Richard Rosenquist, Emanuele Zucca, Peter W Johnson, Gianluca Gaidano, Christopher C Oakes, Francesco Bertoni, Francesco Forconi
Genome-wide promoter methylation of hairy cell leukemia. Blood advances 3 (3) (2020)
Chiara Tarantelli, Eugenio Gaudio, Petra Hillmann, Filippo Spriano, Giulio Sartori, Luca Aresu, Luciano Cascione, Denise Rageot, Ivo Kwee, Florent Beaufils, Emanuele Zucca, Anastasios Stathis, Matthias P Wymann, Vladimir Cmiljanovic, Doriano Fabbro, Francesco Bertoni
The Novel TORC1/2 Kinase Inhibitor PQR620 Has Anti-Tumor Activity in Lymphomas as a Single Agent and in Combination with Venetoclax. Cancers 11 (6) (2019)
Filippo Spriano, Chiara Tarantelli, Eugenio Gaudio, Magdalena M Gerlach, Valdemar Priebe, Luciano Cascione, Elena Bernasconi, Altea Targa, Michele Mascia, Stefan Dirnhofer, Anastasios Stathis, Emanuele Zucca, Francesco Bertoni
Single and combined BTK and PI3Kδ inhibition with acalabrutinib and ACP-319 in pre-clinical models of aggressive lymphomas. British journal of haematology 187 (5) (2019)
Luciano Cascione, Luca Giudice, Serena Ferraresso, Laura Marconato, Diana Giannuzzi, Sara Napoli, Francesco Bertoni, Rosalba Giugno, Luca Aresu
Long Non-Coding RNAs as Molecular Signatures for Canine B-Cell Lymphoma Characterization. Non-coding RNA 5 (3) (2019)
Filippo Spriano, Elaine Y Chung, Nicolo' Panini, Luciano Cascione, Andrea Rinaldi, Eugenio Erba, Anastasios Stathis, Maurizio D'Incalci, Francesco Bertoni, Raffaella Gatta
Trabectedin is a novel chemotherapy agent for diffuse large B cell lymphoma. British journal of haematology 184 (6) (2018)
Chiara Tarantelli, Eugenio Gaudio, Luciano Cascione, Anastasios Stathis, Emanuele Zucca, Francesco Bertoni
In vitro demonstration of synergism with pixantrone combined with targeted agents in lymphomas. British journal of haematology 186 (1) (2018)
Elisa Bergaggio, Chiara Riganti, Giulia Garaffo, Nicoletta Vitale, Elisabetta Mereu, Cecilia Bandini, Elisa Pellegrino, Verdiana Pullano, Paola Omedè, Katia Todoerti, Luciano Cascione, Valentina Audrito, Anna Riccio, Antonio Rossi, Francesco Bertoni, Silvia Deaglio, Antonio Palumbo, Roberto Piva
IDH2 inhibition enhances proteasome inhibitor responsiveness in hematological malignancies. Blood 133 (2) (2018)
Hana Janouskova, Geniver El Tekle, Elisa Bellini, Namrata D Udeshi, Anna Rinaldi, Anna Ulbricht, Tiziano Bernasocchi, Gianluca Civenni, Marco Losa, Tanya Svinkina, Craig M Bielski, Gregory V Kryukov, Luciano Cascione, Sara Napoli, Radoslav I Enchev, David G Mutch, Michael E Carney, Andrew Berchuck, Boris J N Winterhoff, Russell R Broaddus, Peter Schraml, Holger Moch, Francesco Bertoni, Carlo V Catapano, Matthias Peter, Steven A Carr, Levi A Garraway, Peter J Wild, Jean-Philippe P Theurillat
Opposing effects of cancer-type-specific SPOP mutants on BET protein degradation and sensitivity to BET inhibitors. Nature medicine 23 (9) (2017)
Elena Bernasconi, Eugenio Gaudio, Pascale Lejeune, Chiara Tarantelli, Luciano Cascione, Ivo Kwee, Filippo Spriano, Andrea Rinaldi, Afua A Mensah, Elaine Chung, Anastasios Stathis, Stephan Siegel, Norbert Schmees, Matthias Ocker, Emanuele Zucca, Bernard Haendler, Francesco Bertoni
Preclinical evaluation of the BET bromodomain inhibitor BAY 1238097 for the treatment of lymphoma. British journal of haematology 178 (6) (2017)
Luciano Cascione, Andrea Rinaldi, Annalisa Chiappella, Ivo Kwee, Giovannino Ciccone, Michael Altenbuchinger, Christian Kohler, Umberto Vitolo, Giorgio Inghirami, Francesco Bertoni
Diffuse large B cell lymphoma cell of origin by digital expression profiling in the REAL07 Phase 1-2 study. British journal of haematology 182 (3) (2017)
Alberto J Arribas, Andrea Rinaldi, Afua A Mensah, Ivo Kwee, Luciano Cascione, Eloy F Robles, Jose A Martinez-Climent, David Oscier, Luca Arcaini, Luca Baldini, Roberto Marasca, Catherine Thieblemont, Josette Briere, Francesco Forconi, Alberto Zamò, Massimiliano Bonifacio, Manuela Mollejo, Fabio Facchetti, Stephan Dirnhofer, Maurilio Ponzoni, Govind Bhagat, Miguel A Piris, Gianluca Gaidano, Emanuele Zucca, Davide Rossi, Francesco Bertoni
DNA methylation profiling identifies two splenic marginal zone lymphoma subgroups with different clinical and genetic features. Blood 125 (12) (2015)
A Rocci, C C Hofmeister, S Geyer, A Stiff, M Gambella, Luciano Cascione, J Guan, D M Benson, Y A Efebera, T Talabere, V Dirisala, E M Smith, P Omedè, G Isaia, L De Luca, D Rossi, S Gentili, G Uccello, J Consiglio, R Ria, G Benevolo, S Bringhen, V Callea, B Weiss, A Ferro, V Magarotto, H Alder, J C Byrd, M Boccadoro, G Marcucci, A Palumbo, F Pichiorri
Circulating miRNA markers show promise as new prognosticators for multiple myeloma. Leukemia 28 (9) (2014)

Luciano Cascione.css-eqlu8i{font-size:small;padding-left:4px;} (L Cascione)

Publication Activity (10 Years)

Top Topics

Top Venues

Luciano Cascione (L Cascione)