Jennifer R Brown (Jennifer Brown)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 56

Top Topics

Tyrosine Kinase

Chronic Lymphocytic Leukemia

Top Venues

Blood cancer journal

This page only lists publications with an associated author ORCID identifier.

Publications

Jennifer R Brown, Simon Rule, Kara Miller, John Francis Seymour
COVID-19 Vaccination During Therapy in Relation to COVID-19 Death in CLL. Blood advances (2024)
Javid J Moslehi, Richard R Furman, Constantine S Tam, Joe-Elie Salem, Christopher R Flowers, Aileen Cohen, Meng Zhang, Jun Zhang, Lipeng Chen, Han Ma, Jennifer R Brown
Cardiovascular events reported in patients with B-cell malignancies treated with zanubrutinib. Blood advances 8 (10) (2024)
Javid J Moslehi, Richard R Furman, Constantine S Tam, Joe-Elie Salem, Christopher R Flowers, Aileen Cohen, Meng Zhang, Jun Zhang, Lipeng Chen, Han Ma, Jennifer R Brown
Cardiovascular events reported in patients with B-cell malignancies treated with zanubrutinib. Blood advances 8 (10) (2024)
Javid J Moslehi, Richard R Furman, Constantine S Tam, Joe-Elie Salem, Christopher R Flowers, Aileen Cohen, Meng Zhang, Jun Zhang, Lipeng Chen, Han Ma, Jennifer R Brown
Cardiovascular events reported in patients with B-cell malignancies treated with zanubrutinib. Blood advances 8 (10) (2024)
Jennifer R Brown, Kiyomi Mashima, Stacey Fernandes, Aishath Naeem, Samantha Shupe, Rayan Fardoun, Matthew S Davids
Mutations Detected in Real World Clinical Sequencing during BTK Inhibitor Treatment in CLL. Research square (2024)
Mazyar Shadman, Alessandra Tedeschi, Leyla Mohseninejad, Keri Yang, Nicole Lamanna, Sheng Xu, Aileen Cohen, Swetha Challagulla, Mei Xue, Rhys Williams, Susan M O'Brien, Jennifer R Brown, Constantine S Tam
Similar efficacy of ibrutinib arms across ALPINE and ELEVATE-RR trials in relapsed/refractory chronic lymphocytic leukemia: a matching-adjusted indirect comparison. Blood cancer journal 14 (1) (2024)
Mazyar Shadman, Alessandra Tedeschi, Leyla Mohseninejad, Keri Yang, Nicole Lamanna, Sheng Xu, Aileen Cohen, Swetha Challagulla, Mei Xue, Rhys Williams, Susan M O'Brien, Jennifer R Brown, Constantine S Tam
Similar efficacy of ibrutinib arms across ALPINE and ELEVATE-RR trials in relapsed/refractory chronic lymphocytic leukemia: a matching-adjusted indirect comparison. Blood cancer journal 14 (1) (2024)
Javid J Moslehi, Richard R Furman, Constantine S Tam, Joe-Elie Salem, Christopher R Flowers, Aileen Cohen, Meng Zhang, Jun Zhang, Lipeng Chen, Han Ma, Jennifer R Brown
Cardiovascular events reported in patients with B-cell malignancies treated with zanubrutinib. Blood advances 8 (10) (2024)
Jennifer R Brown, Kiyomi Mashima, Stacey Fernandes, Aishath Naeem, Samantha Shupe, Rayan Fardoun, Matthew S Davids
Mutations Detected in Real World Clinical Sequencing during BTK Inhibitor Treatment in CLL. Research square (2024)
Javid J Moslehi, Richard R Furman, Constantine S Tam, Joe-Elie Salem, Christopher R Flowers, Aileen Cohen, Meng Zhang, Jun Zhang, Lipeng Chen, Han Ma, Jennifer R Brown
Cardiovascular events reported in patients with B-cell malignancies treated with zanubrutinib. Blood advances (2024)
Mazyar Shadman, Alessandra Tedeschi, Leyla Mohseninejad, Keri Yang, Nicole Lamanna, Sheng Xu, Aileen Cohen, Swetha Challagulla, Mei Xue, Rhys Williams, Susan M O'Brien, Jennifer R Brown, Constantine S Tam
Similar efficacy of ibrutinib arms across ALPINE and ELEVATE-RR trials in relapsed/refractory chronic lymphocytic leukemia: a matching-adjusted indirect comparison. Blood cancer journal 14 (1) (2024)
Deepti Gadi, Stephen P Martindale, Pui Yan Chiu, Jasneet Khalsa, Pei-Hsuan Chen, Stacey M Fernandes, Zixu Wang, Svitlana Tyekucheva, John-Hanson Machado, David C Fisher, Philippe Armand, Matthew S Davids, Scott Rodig, Barbara Sherry, Jennifer R Brown
Circulating Th17 T cells at treatment onset predict autoimmune toxicity of PI3Kδ inhibitors. Blood cancer journal 13 (1) (2023)
Erin M Parry, Ignaty Leshchiner, Romain Guieze, Connor Johnson, Eugen Tausch, Sameer A Parikh, Camilla K Lemvigh, Julien Broseus, Sebastien Hergalant, Conor Messer, Filippo Utro, Chaya Levovitz, Kahn Rhrissorrakrai, Liang Li, Daniel Rosebrock, Shanye Yin, Stephanie L Deng, Kara Slowik, Raquel Jacobs, Teddy Huang, Shuqiang Li, Geoffrey G Fell, Robert A Redd, Ziao Lin, Binyamin Asher Knisbacher, Dimitri Livitz, Christof Schneider, Neil Ruthen, Liudmila Elagina, Amaro Taylor-Weiner, Bria Persaud, Aina Z Martinez, Stacey M Fernandes, Noelia Purroy, Annabelle J Anandappa, Jialin Ma, Julian M Hess, Laura Z Rassenti, Thomas J Kipps, Nitin Jain, William G Wierda, Florence Cymbalista, Pierre Feugier, Neil E Kay, Kenneth J Livak, Brian P Danysh, Chip Stewart, Donna S Neuberg, Matthew S Davids, Jennifer R Brown, Laxmi Parida, Stephan Stilgenbauer, Gad A Getz, Catherine J Wu
Evolutionary history of transformation from chronic lymphocytic leukemia to Richter syndrome. Nature medicine 29 (1) (2023)
John Francis Seymour, John C Byrd, Paolo Ghia, Arnon P Kater, Asher A Chanan-Khan, Richard R Furman, Susan M O'Brien, Jennifer R Brown, Talha Munir, Anthony Mato, Stephan Stilgenbauer, Naghmana Bajwa, Paulo A Palhares de Miranda, Kara Higgins, Ellie John, Marianne de Borja, Wojciech Jurczak, Jennifer A Woyach
Detailed safety profile of acalabrutinib vs ibrutinib in previously treated chronic lymphocytic leukemia in ELEVATE-RR. Blood (2023)
Erin M Parry, Ignaty Leshchiner, Romain Guieze, Connor Johnson, Eugen Tausch, Sameer A Parikh, Camilla K Lemvigh, Julien Broseus, Sebastien Hergalant, Conor Messer, Filippo Utro, Chaya Levovitz, Kahn Rhrissorrakrai, Liang Li, Daniel Rosebrock, Shanye Yin, Stephanie L Deng, Kara Slowik, Raquel Jacobs, Teddy Huang, Shuqiang Li, Geoffrey G Fell, Robert A Redd, Ziao Lin, Binyamin Asher Knisbacher, Dimitri Livitz, Christof Schneider, Neil Ruthen, Liudmila Elagina, Amaro Taylor-Weiner, Bria Persaud, Aina Z Martinez, Stacey M Fernandes, Noelia Purroy, Annabelle J Anandappa, Jialin Ma, Julian M Hess, Laura Z Rassenti, Thomas J Kipps, Nitin Jain, William G Wierda, Florence Cymbalista, Pierre Feugier, Neil E Kay, Kenneth J Livak, Brian P Danysh, Chip Stewart, Donna S Neuberg, Matthew S Davids, Jennifer R Brown, Laxmi Parida, Stephan Stilgenbauer, Gad A Getz, Catherine J Wu
Evolutionary history of transformation from chronic lymphocytic leukemia to Richter syndrome. Nature medicine 29 (1) (2023)
Erin M Parry, Ignaty Leshchiner, Romain Guieze, Connor Johnson, Eugen Tausch, Sameer A Parikh, Camilla K Lemvigh, Julien Broseus, Sebastien Hergalant, Conor Messer, Filippo Utro, Chaya Levovitz, Kahn Rhrissorrakrai, Liang Li, Daniel Rosebrock, Shanye Yin, Stephanie L Deng, Kara Slowik, Raquel Jacobs, Teddy Huang, Shuqiang Li, Geoffrey G Fell, Robert A Redd, Ziao Lin, Binyamin Asher Knisbacher, Dimitri Livitz, Christof Schneider, Neil Ruthen, Liudmila Elagina, Amaro Taylor-Weiner, Bria Persaud, Aina Z Martinez, Stacey M Fernandes, Noelia Purroy, Annabelle J Anandappa, Jialin Ma, Julian M Hess, Laura Z Rassenti, Thomas J Kipps, Nitin Jain, William G Wierda, Florence Cymbalista, Pierre Feugier, Neil E Kay, Kenneth J Livak, Brian P Danysh, Chip Stewart, Donna S Neuberg, Matthew S Davids, Jennifer R Brown, Laxmi Parida, Stephan Stilgenbauer, Gad A Getz, Catherine J Wu
Evolutionary history of transformation from chronic lymphocytic leukemia to Richter syndrome. Nature medicine (2023)
Erin M Parry, Ignaty Leshchiner, Romain Guieze, Connor Johnson, Eugen Tausch, Sameer A Parikh, Camilla K Lemvigh, Julien Broseus, Sebastien Hergalant, Conor Messer, Filippo Utro, Chaya Levovitz, Kahn Rhrissorrakrai, Liang Li, Daniel Rosebrock, Shanye Yin, Stephanie L Deng, Kara Slowik, Raquel Jacobs, Teddy Huang, Shuqiang Li, Geoffrey G Fell, Robert A Redd, Ziao Lin, Binyamin Asher Knisbacher, Dimitri Livitz, Christof Schneider, Neil Ruthen, Liudmila Elagina, Amaro Taylor-Weiner, Bria Persaud, Aina Z Martinez, Stacey M Fernandes, Noelia Purroy, Annabelle J Anandappa, Jialin Ma, Julian M Hess, Laura Z Rassenti, Thomas J Kipps, Nitin Jain, William G Wierda, Florence Cymbalista, Pierre Feugier, Neil E Kay, Kenneth J Livak, Brian P Danysh, Chip Stewart, Donna S Neuberg, Matthew S Davids, Jennifer R Brown, Laxmi Parida, Stephan Stilgenbauer, Gad A Getz, Catherine J Wu
Evolutionary history of transformation from chronic lymphocytic leukemia to Richter syndrome. Nature medicine 29 (1) (2023)
Erin M Parry, Ignaty Leshchiner, Romain Guieze, Connor Johnson, Eugen Tausch, Sameer A Parikh, Camilla K Lemvigh, Julien Broseus, Sebastien Hergalant, Conor Messer, Filippo Utro, Chaya Levovitz, Kahn Rhrissorrakrai, Liang Li, Daniel Rosebrock, Shanye Yin, Stephanie L Deng, Kara Slowik, Raquel Jacobs, Teddy Huang, Shuqiang Li, Geoffrey G Fell, Robert A Redd, Ziao Lin, Binyamin Asher Knisbacher, Dimitri Livitz, Christof Schneider, Neil Ruthen, Liudmila Elagina, Amaro Taylor-Weiner, Bria Persaud, Aina Z Martinez, Stacey M Fernandes, Noelia Purroy, Annabelle J Anandappa, Jialin Ma, Julian M Hess, Laura Z Rassenti, Thomas J Kipps, Nitin Jain, William G Wierda, Florence Cymbalista, Pierre Feugier, Neil E Kay, Kenneth J Livak, Brian P Danysh, Chip Stewart, Donna S Neuberg, Matthew S Davids, Jennifer R Brown, Laxmi Parida, Stephan Stilgenbauer, Gad A Getz, Catherine J Wu
Evolutionary history of transformation from chronic lymphocytic leukemia to Richter syndrome. Nature medicine 29 (1) (2023)
Deepti Gadi, Stephen P Martindale, Pui Yan Chiu, Jasneet Khalsa, Pei-Hsuan Chen, Stacey M Fernandes, Zixu Wang, Svitlana Tyekucheva, John-Hanson Machado, David C Fisher, Philippe Armand, Matthew S Davids, Scott Rodig, Barbara Sherry, Jennifer R Brown
Circulating Th17 T cells at treatment onset predict autoimmune toxicity of PI3Kδ inhibitors. Blood cancer journal 13 (1) (2023)
Deepti Gadi, Stephen P Martindale, Pui Yan Chiu, Jasneet Khalsa, Pei-Hsuan Chen, Stacey M Fernandes, Zixu Wang, Svitlana Tyekucheva, John-Hanson Machado, David C Fisher, Philippe Armand, Matthew S Davids, Scott Rodig, Barbara Sherry, Jennifer R Brown
Circulating Th17 T cells at treatment onset predict autoimmune toxicity of PI3Kδ inhibitors. Blood cancer journal 13 (1) (2023)
Ali AlJabban, Hyun-Il Paik, Jon C Aster, Nancy Berliner, Jennifer Brouillard, Jennifer R Brown, Kathleen H Burns, Jorge J Castillo, James Card, Paola Dal Cin, Daniel J DeAngelo, David M Dorfman, Benjamin L Ebert, Jacqueline S Garcia, Caron A Jacobson, Hakim Lakhani, Jacob P Laubach, Azra H Ligon, Neal I Lindeman, R Coleman Lindsley, Scott B Lovitch, Marlise R Luskin, Elizabeth A Morgan, Andrew Nowak, Athena Petrides, Geraldine S Pinkus, Olga Pozdnyakova, David P Steensma, Richard M Stone, Olga K Weinberg, Eric S Winer, Annette S Kim
Optimization of Advanced Molecular Genetic Testing Utilization in Hematopathology: A Goldilocks Approach to Bone Marrow Testing. JCO oncology practice (2023)
Alberto J Arribas, Sara Napoli, Luciano Cascione, Laura Barnabei, Giulio Sartori, Eleonora Cannas, Eugenio Gaudio, Chiara Tarantelli, Afua Adjeiwaa Mensah, Filippo Spriano, Antonella Zucchetto, Francesca Maria Rossi, Andrea Rinaldi, Manuel Castro de Moura, Sandra Jovic, Roberta Bordone Pittau, Anastasios Stathis, Georg Stussi, Valter Gattei, Jennifer R Brown, Manel Esteller, Emanuele Zucca, Davide Rossi, Francesco Bertoni
ERBB4-Mediated Signaling Is a Mediator of Resistance to PI3K and BTK Inhibitors in B-cell Lymphoid Neoplasms. Molecular cancer therapeutics (2023)
Deepti Gadi, Stephen P Martindale, Pui Yan Chiu, Jasneet Khalsa, Pei-Hsuan Chen, Stacey M Fernandes, Zixu Wang, Svitlana Tyekucheva, John-Hanson Machado, David C Fisher, Philippe Armand, Matthew S Davids, Scott Rodig, Barbara Sherry, Jennifer R Brown
Circulating Th17 T cells at treatment onset predict autoimmune toxicity of PI3Kδ inhibitors. Blood cancer journal 13 (1) (2023)
Deepti Gadi, Stephen P Martindale, Pui Yan Chiu, Jasneet Khalsa, Pei-Hsuan Chen, Stacey M Fernandes, Zixu Wang, Svitlana Tyekucheva, John-Hanson Machado, David C Fisher, Philippe Armand, Matthew S Davids, Scott Rodig, Barbara Sherry, Jennifer R Brown
Circulating Th17 T cells at treatment onset predict autoimmune toxicity of PI3Kδ inhibitors. Blood cancer journal 13 (1) (2023)
Christine E Ryan, Danielle M Brander, Paul M Barr, Svitlana Tyekucheva, Liam R Hackett, Mary C Collins, Stacey M Fernandes, Yue Ren, Yinglu Zhou, Mikaela M McDonough, Heather A Walker, Monica R McEwan, Jeremy S Abramson, Eric D Jacobsen, Ann S LaCasce, David C Fisher, Jennifer R Brown, Matthew S Davids
A phase 1b study of ibrutinib in combination with obinutuzumab in patients with relapsed or refractory chronic lymphocytic leukemia. Leukemia (2023)
Deepti Gadi, Stephen P Martindale, Pui Yan Chiu, Jasneet Khalsa, Pei-Hsuan Chen, Stacey M Fernandes, Zixu Wang, Svitlana Tyekucheva, John-Hanson Machado, David C Fisher, Philippe Armand, Matthew S Davids, Scott Rodig, Barbara Sherry, Jennifer R Brown
Circulating Th17 T cells at treatment onset predict autoimmune toxicity of PI3Kδ inhibitors. Blood cancer journal 13 (1) (2023)
Anthony R Mato, Jennifer A Woyach, Jennifer R Brown, Paolo Ghia, Krish Patel, Toby A Eyre, Talha Munir, Ewa Lech-Maranda, Nicole Lamanna, Constantine S Tam, Nirav N Shah, Catherine C Coombs, Chaitra S Ujjani, Bita Fakhri, Chan Yoon Y Cheah, Manish R Patel, Alvaro J Alencar, Jonathon B Cohen, James N Gerson, Ian W Flinn, Shuo Ma, Deepa Jagadeesh, Joanna M Rhodes, Francisco Hernandez-Ilizaliturri, Pier L Zinzani, John Francis Seymour, Minna Balbas, Binoj Nair, Paolo Abada, Chunxiao Wang, Amy S Ruppert, Denise Wang, Donald E Tsai, William G Wierda, Wojciech Jurczak
Pirtobrutinib after a Covalent BTK Inhibitor in Chronic Lymphocytic Leukemia. The New England journal of medicine 389 (1) (2023)
Jasneet Kaur Khalsa, Justin Cha, Filippo Utro, Aishath Naeem, Ishwarya Murali, Yanan Kuang, Kevin A Vasquez, Liang Li, Svitlana Tyekucheva, Stacey M Fernandes, Lauren Véronèse, Romain Guieze, Binu Sasi, Zixu Wang, John-Hanson Machado, Harrison P Bai, Maryam Alasfour, Kahn Rhrissorrakrai, Chaya Levovitz, Brian P Danysh, Kara Slowik, Raquel A Jacobs, Matthew S Davids, Cloud P Paweletz, Ignaty Leshchiner, Laxmi Parida, Gad Getz, Jennifer R Brown
Genetic events associated with venetoclax resistance in CLL identified by whole exome sequencing of patient samples. Blood (2023)
Yiming Wu, Meiling Jin, Mike Minh Fernandez, Kevyn Lopez Hart, Aijun Liao, Xinzhou Ge, Stacey M Fernandes, Tinisha McDonald, Zhenhua Chen, Daniel Röth, Lucy Y Ghoda, Guido Marcucci, Markus Kalkum, Raju K Pillai, Alexey V Danilov, Jingyi Jessica Li, Jianjun Chen, Jennifer R Brown, Steven T Rosen, Tanya Siddiqi, Lili Wang
METTL3-Mediated m6A Modification Controls Splicing Factor Abundance and Contributes to Aggressive CLL. Blood cancer discovery (2023)
Peter Hillmen, Barbara Eichhorst, Jennifer R Brown, Nicole Lamanna, Susan M O'Brien, Constantine S Tam, Lugui Qiu, Maciej Kazmierczak, Keshu Zhou, Martin Simkovic, Jiří Mayer, Amanda Gillespie-Twardy, Mazyar Shadman, Alessandra Ferrajoli, Peter S Ganly, Robert Weinkove, Sebastian Grosicki, Andrzej Mital, Tadeusz Robak, Anders Österborg, Habte A Yimer, Tommi Salmi, Meng Ji, Jessica Yecies, Adam Idoine, Kenneth Wu, Jane Huang, Wojciech Jurczak
Zanubrutinib Versus Ibrutinib in Relapsed/Refractory Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma: Interim Analysis of a Randomized Phase III Trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2022)
Murali K Mamidi, Hasan Mahmud, Guru P Maiti, Mariana T Mendez, Stacey M Fernandes, Sara K Vesely, Jennifer Holter-Chakrabarty, Jennifer R Brown, Asish K Ghosh
Idelalisib activates AKT via increased recruitment of PI3Kδ/PI3Kβ to BCR signalosome while reducing PDK1 in post-therapy CLL cells. Leukemia 36 (7) (2022)
Yanping Yin, Paschalis Athanasiadis, Linda Karlsen, Aleksandra Urban, Haifeng Xu, Ishwarya Murali, Stacey M Fernandes, Alberto J Arribas, Abdul K Hilli, Kjetil Taskén, Francesco Bertoni, Anthony R Mato, Emmanuel Normant, Jennifer R Brown, Geir Erland Tjønnfjord, Tero Aittokallio, Sigrid S Skånland
Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (20) (2022)
Reid W Merryman, Robert A Redd, Eleanor Taranto, Gulrayz Ahmed, Erin Jeter, Kristin M McHugh, Jennifer R Brown, Jennifer L Crombie, Matthew S Davids, David C Fisher, Arnold S Freedman, Eric D Jacobsen, Caron A Jacobson, Austin I Kim, Ann Steward LaCasce, Samuel Y Ng, Oreofe O Odejide, Erin M Parry, Heather Jacene, Hyesun Park, Parastoo B Dahi, Yago L Nieto, Robin M Joyce, Yi-Bin Chen, Margaret A Shipp, Alex F Herrera, Philippe Armand
Minimal residual disease in patients with diffuse large B-cell lymphoma undergoing autologous stem cell transplantation. Blood advances (2022)
Binyamin Asher Knisbacher, Ziao Lin, Cynthia K Hahn, Ferran Nadeu, Martí Duran-Ferrer, Kristen E Stevenson, Eugen Tausch, Julio Delgado, Alex Barbera-Mourelle, Amaro Taylor-Weiner, Pablo Bousquets Muñoz, Ander Díaz-Navarro, Andrew Dunford, Shankara Anand, Helene Kretzmer, Jesus Gutierrez-Abril, Sara López-Tamargo, Stacey M Fernandes, Clare Sun, Mariela Sivina, Laura Z Rassenti, Christof Schneider, Shuqiang Li, Laxmi Parida, Alexander Meissner, François Aguet, Jan A Burger, Adrian Wiestner, Thomas J Kipps, Jennifer R Brown, Michael Hallek, Chip Stewart, Donna S Neuberg, José Ignacio Martin-Subero, Xose S Puente, Stephan Stilgenbauer, Catherine J Wu, Elias Campo, Gad A Getz
Molecular map of chronic lymphocytic leukemia and its impact on outcome. Nature genetics 54 (11) (2022)
Benjamin L Lampson, Aditi Gupta, Svitlana Tyekucheva, Kiyomi Mashima, Anna Petráčková, Zixu Wang, Natalia Wojciechowska, Conner J Shaughnessy, Peter O Baker, Stacey M Fernandes, Samantha Shupe, John-Hanson Machado, Rayan Fardoun, Annette S Kim, Jennifer R Brown
Rare Germline ATM Variants Influence the Development of Chronic Lymphocytic Leukemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2022)
Deepti Gadi, Alec Griffith, Zixu Wang, Svitlana Tyekucheva, Vanessa Rai, Stacey M Fernandes, John-Hanson Machado, Veerendra Munugalavadla, James Lederer, Jennifer R Brown
Idelalisib reduces regulatory T cells and activates T helper 17 cell differentiation in relapsed refractory patients with chronic lymphocytic leukaemia. British journal of haematology 197 (2) (2022)
Aishath Naeem, Filippo Utro, Qing Wang, Justin Cha, Mauno Vihinen, Stephen P Martindale, Yinglu Zhou, Yue Ren, Svitlana Tyekucheva, Annette S Kim, Stacey M Fernandes, Gordon Saksena, Kahn Rhrissorrakrai, Chaya Levovitz, Brian P Danysh, Kara Slowik, Raquel A Jacobs, Matthew S Davids, James A Lederer, Rula Zain, Carl Inge Edvard Smith, Ignaty Leshchiner, Laxmi Parida, Gad Getz, Jennifer R Brown
Pirtobrutinib Targets BTK C481S in Ibrutinib-Resistant CLL but Second-Site BTK Mutations Lead to Resistance. Blood advances (2022)
Alexey V Danilov, Stephen E Spurgeon, Tanya Siddiqi, Anne-Marie Quinson, Daniela Maier, Dionne Smith, Jennifer R Brown
A phase Ib, open label, dose escalation trial of the anti-CD37 monoclonal antibody, BI 836826, in combination with ibrutinib in patients with relapsed/refractory chronic lymphocytic leukemia. Investigational new drugs 39 (4) (2021)
Nina D Wagner-Johnston, Jeff Sharman, Richard R Furman, Gilles Salles, Jennifer R Brown, Tadeusz Robak, Lin Gu, Guan Xing, Rebecca J Chan, Nishanthan Rajakumaraswamy, Ajay K Gopal
Idelalisib immune-related toxicity is associated with improved treatment response. Leukemia & lymphoma 62 (12) (2021)
Amy S Ruppert, Allison M Booth, Wei Ding, Nancy L Bartlett, Danielle M Brander, Steven Coutre, Jennifer R Brown, Sreenivasa Nattam, Richard A Larson, Harry Erba, Mark R Litzow, Carolyn Owen, Charles S Kuzma, Jeremy S Abramson, Richard F Little, Scott E Smith, Richard M Stone, John C Byrd, Sumithra J Mandrekar, Jennifer A Woyach
Adverse event burden in older patients with CLL receiving bendamustine plus rituximab or ibrutinib regimens: Alliance A041202. Leukemia 35 (10) (2021)
Matthew S Davids, Kerry A Rogers, Svitlana Tyekucheva, Zixu Wang, Samantha Pazienza, Sarah K Renner, Josie Montegaard, Udochukwu O Ihuoma, Timothy Z Lehmberg, Erin M Parry, Catherine J Wu, Caron A Jacobson, David C Fisher, Philip A Thompson, Jennifer R Brown
Venetoclax plus Dose-Adjusted R-EPOCH (VR-EPOCH) for Richter's Syndrome. Blood (2021)
Bart Vanhaesebroeck, Matthew W D Perry, Jennifer R Brown, Fabrice Andre, Klaus Okkenhaug
PI3K inhibitors are finally coming of age. Nature reviews. Drug discovery 20 (10) (2021)
Jennifer L Crombie, Jennifer R Brown
The future of antibody therapy in chronic lymphocytic leukemia. Expert opinion on emerging drugs 26 (3) (2021)
Pavan Bachireddy, Christina Ennis, Vinhkhang N Nguyen, Satyen H Gohil, M Kendell Clement, Sachet A Shukla, Juliet Forman, Nikolaos Barkas, Samuel S Freeman, Natalie Bavli, Liudmila Elagina, Ignaty Leshchiner, Arman W Mohammad, Nathan D Mathewson, Derin B Keskin, Laura Z Rassenti, Thomas J Kipps, Jennifer R Brown, Gad A Getz, Vincent T Ho, Andreas Gnirke, Donna S Neuberg, Robert J Soiffer, Jerome Ritz, Edwin P Alyea, Peter V Kharchenko, Catherine J Wu
Distinct evolutionary paths in chronic lymphocytic leukemia during resistance to the graft-versus-leukemia effect. Science translational medicine 12 (561) (2021)
Richard R Furman, John C Byrd, Roger G Owen, Susan M O'Brien, Jennifer R Brown, Peter Hillmen, Deborah M Stephens, Nataliya Chernyukhin, Tamara Lezhava, Ahmed M Hamdy, Raquel Izumi, Priti Patel, Marshall Baek, Beth Christian, Martin J S Dyer, Matthew J Streetly, Clare Sun, Simon A Rule, Michael L Wang, Paolo Ghia, Wojciech Jurczak, John M Pagel, Jeff P Sharman
Pooled analysis of safety data from clinical trials evaluating acalabrutinib monotherapy in mature B-cell malignancies. Leukemia 35 (11) (2021)
Jennifer R Brown
Targeting MCL-1 and BCL-2: a 1-2 punch. Blood 137 (20) (2021)
Ishwarya Murali, Siddha Kasar, Aishath Naeem, Svitlana Tyekucheva, Jasneet Kaur Khalsa, Emily M Thrash, Gilad Itchaki, Dimitri Livitz, Ignaty Leshchiner, Shuai Dong, Stacey M Fernandes, Gad Getz, Amy Johnson, Jennifer R Brown
Activation of the MAPK pathway mediates resistance to PI3K inhibitors in chronic lymphocytic leukemia. Blood 138 (1) (2021)
Deepti Gadi, Alec M Griffith, Svitlana Tyekucheva, Zixu Wang, Vanessa Rai, Alexander Vartanov, Emily M Thrash, Stacey M Fernandes, Timothy Z Lehmberg, Brandon Lee, Stephen P Martindale, John-Hanson Machado, Oreofe Odejide, Philippe Armand, David C Fisher, Jon Arnason, Matthew S Davids, James A Lederer, Jennifer R Brown
A T cell inflammatory phenotype is associated with autoimmune toxicity of the PI3K inhibitor duvelisib in chronic lymphocytic leukemia. Leukemia (2021)
William G Wierda, Andrew Rawstron, Florence Cymbalista, Xavier Badoux, Davide Rossi, Jennifer R Brown, Alexander Egle, Virginia Abello, Eduardo Cervera Ceballos, Yair Herishanu, Stephen P Mulligan, Carsten Utoft Niemann, Colin P Diong, Teoman Soysal, Ritsuro Suzuki, Hoa T T Tran, Shang-Ju Wu, Carolyn Owen, Stephan Stilgenbauer, Paolo Ghia, Peter Hillmen
Measurable residual disease in chronic lymphocytic leukemia: expert review and consensus recommendations. Leukemia 35 (11) (2021)
Jennifer L Crombie, Amy C Sherman, Chi-An Cheng, Christine E Ryan, Rebecca Zon, Michaël Desjardins, Peter Baker, Mikaela McDonough, Natalie Izaguirre, Bruce Bausk, Jonathan Krauss, Tal Gilboa, Yasmeen Senussi, David R Walt, Matthew S Davids, Jennifer R Brown, Philippe Armand, Lindsey R Baden, Nicolas Issa
Activity of mRNA COVID-19 vaccines in patients with lymphoid malignancies. Blood advances 5 (16) (2021)
Jennifer R Brown, Andrew Zelenetz, Richard Furman, Nicole Lamanna, Anthony Mato, Marco Montillo, Susan O'Brien, Ronald Dubowy, Lin Gu, Veerendra Munugalavadla, Tadeusz Robak, Peter Hillmen
Risk factors for grade 3/4 transaminase elevation in patients with chronic lymphocytic leukemia treated with idelalisib. Leukemia 34 (12) (2020)
Benjamin L Lampson, Haesook T Kim, Matthew S Davids, Jeremy S Abramson, Arnold S Freedman, Caron A Jacobson, Philippe A Armand, Robin M Joyce, Jon E Arnason, Laura Z Rassenti, Thomas J Kipps, Joshua Alexander Fein, Stacey M Fernandes, John R Hanna, David C Fisher, Jennifer R Brown
Efficacy results of a phase 2 trial of first-line idelalisib plus ofatumumab in chronic lymphocytic leukemia. Blood advances 3 (7) (2020)
Matthew L Chase, Reid Merryman, David C Fisher, Eric Jacobsen, Ann LaCasce, Caron Jacobson, Arnold Freedman, Matthew S Davids, Jennifer R Brown, Allison Jacob, Philippe Armand, Jennifer Crombie
A prospective study of minimal residual disease in patients with diffuse large B-cell lymphoma using an Ig-NGS assay. Leukemia & lymphoma 62 (2) (2020)
Jennifer R Brown
DUO delivers for duvelisib. Blood 132 (23) (2019)
Jennifer R Brown, Javid Moslehi, Michael S Ewer, Susan M O'Brien, Paolo Ghia, Florence Cymbalista, Tait D Shanafelt, Graeme Fraser, Simon A Rule, Steven E Coutre, Marie-Sarah Dilhuydy, Paula Cramer, Ulrich Jaeger, Martin Dreyling, John C Byrd, Steven P Treon, Emily Y Liu, Stephen Chang, Amulya Bista, Rama Vempati, Lisa Boornazian, Rudolph Valentino, Vijay Reddy, Michelle Mahler, Huiying Yang, Thorsten Graef, Jan A Burger
Incidence of and risk factors for major haemorrhage in patients treated with ibrutinib: An integrated analysis. British journal of haematology 184 (4) (2018)
Ma Reina Improgo, Bethany Tesar, Josephine L Klitgaard, Reuma Magori-Cohen, Lijian Yu, Siddha Kasar, Divya Chaudhary, Wenyan Miao, Stacey M Fernandes, Kevin Hoang, William F Westlin, Haesook T Kim, Jennifer R Brown
MYD88 L265P mutations identify a prognostic gene expression signature and a pathway for targeted inhibition in CLL. British journal of haematology 184 (6) (2018)