Ludo Van Den Bosch

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 37

Top Topics

Amyotrophic Lateral Sclerosis

Histone Deacetylase

Top Venues

Acta neuropathologica

International journal of molecular sciences

Experimental & molecular medicine

The EMBO journal

This page only lists publications with an associated author ORCID identifier.

Publications

Paraskevi Tziortzouda, Jolien Steyaert, Wendy Scheveneels, Adria Sicart, Katarina Stoklund Dittlau, Adriana Margarida Barbosa Correia, Thibaut Burg, Arun Pal, Andreas Hermann, Philip Van Damme, Thomas G Moens, Ludo Van Den Bosch
PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transport. Acta neuropathologica 147 (1) (2024)
Paraskevi Tziortzouda, Jolien Steyaert, Wendy Scheveneels, Adria Sicart, Katarina Stoklund Dittlau, Adriana Margarida Barbosa Correia, Thibaut Burg, Arun Pal, Andreas Hermann, Philip Van Damme, Thomas G Moens, Ludo Van Den Bosch
PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transport. Acta neuropathologica 147 (1) (2024)
Jonas Van Lent, Robert Prior, Gonzalo Pérez Siles, Anthony N Cutrupi, Marina L Kennerson, Tim Vangansewinkel, Esther Wolfs, Bipasha Mukherjee-Clavin, Zachary S Nevin, Luke Judge, Bruce R Conklin, Henna Tyynismaa, Alex J Clark, David L H Bennett, Ludo Van Den Bosch, Mario Saporta, Vincent Timmerman
Advances and challenges in modeling inherited peripheral neuropathies using iPSCs. Experimental & molecular medicine (2024)
Robert Prior, Alessio Silva, Tim Vangansewinkel, Jakub Idkowiak, Arun Kumar Tharkeshwar, Tom P Hellings, Iliana Michailidou, Jeroen Vreijling, Maarten Loos, Bastijn Koopmans, Nina Vlek, Cedrick Agaser, Thomas B Kuipers, Christine Michiels, Elisabeth Rossaert, Stijn Verschoren, Wendy Vermeire, Vincent de Laat, Jonas Dehairs, Kristel Eggermont, Diede van den Biggelaar, Adekunle T Bademosi, Frederic A Meunier, Martin vandeVen, Philip Van Damme, Hailiang Mei, Johannes V Swinnen, Ivo Lambrichts, Frank Baas, Kees Fluiter, Esther Wolfs, Ludo Van Den Bosch
PMP22 duplication dysregulates lipid homeostasis and plasma membrane organization in developing human Schwann cells. Brain : a journal of neurology 147 (9) (2024)
Paraskevi Tziortzouda, Jolien Steyaert, Wendy Scheveneels, Adria Sicart, Katarina Stoklund Dittlau, Adriana Margarida Barbosa Correia, Thibaut Burg, Arun Pal, Andreas Hermann, Philip Van Damme, Thomas G Moens, Ludo Van Den Bosch
PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transport. Acta neuropathologica 147 (1) (2024)
Paraskevi Tziortzouda, Jolien Steyaert, Wendy Scheveneels, Adria Sicart, Katarina Stoklund Dittlau, Adriana Margarida Barbosa Correia, Thibaut Burg, Arun Pal, Andreas Hermann, Philip Van Damme, Thomas G Moens, Ludo Van Den Bosch
PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transport. Acta neuropathologica 147 (1) (2024)
Jonas Van Lent, Robert Prior, Gonzalo Pérez Siles, Anthony N Cutrupi, Marina L Kennerson, Tim Vangansewinkel, Esther Wolfs, Bipasha Mukherjee-Clavin, Zachary S Nevin, Luke Judge, Bruce R Conklin, Henna Tyynismaa, Alex J Clark, David L H Bennett, Ludo Van Den Bosch, Mario Saporta, Vincent Timmerman
Advances and challenges in modeling inherited peripheral neuropathies using iPSCs. Experimental & molecular medicine 56 (6) (2024)
Paraskevi Tziortzouda, Jolien Steyaert, Wendy Scheveneels, Adria Sicart, Katarina Stoklund Dittlau, Adriana Margarida Barbosa Correia, Thibaut Burg, Arun Pal, Andreas Hermann, Philip Van Damme, Thomas G Moens, Ludo Van Den Bosch
PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transport. Acta neuropathologica 147 (1) (2024)
Jonas Van Lent, Robert Prior, Gonzalo Pérez Siles, Anthony N Cutrupi, Marina L Kennerson, Tim Vangansewinkel, Esther Wolfs, Bipasha Mukherjee-Clavin, Zachary S Nevin, Luke Judge, Bruce R Conklin, Henna Tyynismaa, Alex J Clark, David L H Bennett, Ludo Van Den Bosch, Mario Saporta, Vincent Timmerman
Advances and challenges in modeling inherited peripheral neuropathies using iPSCs. Experimental & molecular medicine 56 (6) (2024)
Jonas Van Lent, Robert Prior, Gonzalo Pérez Siles, Anthony N Cutrupi, Marina L Kennerson, Tim Vangansewinkel, Esther Wolfs, Bipasha Mukherjee-Clavin, Zachary S Nevin, Luke Judge, Bruce R Conklin, Henna Tyynismaa, Alex J Clark, David L H Bennett, Ludo Van Den Bosch, Mario Saporta, Vincent Timmerman
Advances and challenges in modeling inherited peripheral neuropathies using iPSCs. Experimental & molecular medicine 56 (6) (2024)
Rita Sattler, Bryan J Traynor, Janice Robertson, Ludo Van Den Bosch, Sami J Barmada, Clive N Svendsen, Matthew D Disney, Tania F Gendron, Philip C Wong, Matthew C Kiernan, Adam L Boxer, Suma Babu, Michael Benatar, Michael Kurnellas, Jonathan Daniel Rohrer, Christopher J Donnelly, Lynette M Bustos, Kendall Van Keuren-Jensen, Penny A Dacks, Marwan N Sabbagh, null null
Roadmap for C9ORF72 in Frontotemporal Dementia and Amyotrophic Lateral Sclerosis: Report on the C9ORF72 FTD/ALS Summit. Neurology and therapy (2023)
Martina Gatti, Katarina Stoklund Dittlau, Francesca Beretti, Laura Yedigaryan, Manuela Zavatti, Pietro Cortelli, Antonella Sola, Emma Bertucci, Ludo Van Den Bosch, Maurilio Sampaolesi, Tullia Maraldi
Human Neuromuscular Junction on a Chip: Impact of Amniotic Fluid Stem Cell Extracellular Vesicles on Muscle Atrophy and NMJ Integrity. International journal of molecular sciences 24 (5) (2023)
Carola Torazza, Francesca Provenzano, Elena Gallia, Maria Cerminara, Matilde Balbi, Tiziana Bonifacino, Sara Tessitore, Silvia Ravera, Cesare Usai, Ilaria Musante, Aldamaria Puliti, Ludo Van Den Bosch, Paymaan Jafar-Nejad, Frank Rigo, Marco Milanese, Giambattista Bonanno
Genetic Downregulation of the Metabotropic Glutamate Receptor Type 5 Dampens the Reactive and Neurotoxic Phenotype of Adult ALS Astrocytes. Cells 12 (15) (2023)
Jimmy Beckers, Arun Kumar Tharkeshwar, Laura Fumagalli, Matilde Contardo, Evelien Van Schoor, Raheem Fazal, Dietmar Rudolf Thal, Siddharthan Chandran, Renzo Mancuso, Ludo Van Den Bosch, Philip Van Damme
A toxic gain-of-function mechanism in C9orf72 ALS impairs the autophagy-lysosome pathway in neurons. Acta neuropathologica communications 11 (1) (2023)
Martina Gatti, Katarina Stoklund Dittlau, Francesca Beretti, Laura Yedigaryan, Manuela Zavatti, Pietro Cortelli, Antonella Sola, Emma Bertucci, Ludo Van Den Bosch, Maurilio Sampaolesi, Tullia Maraldi
Human Neuromuscular Junction on a Chip: Impact of Amniotic Fluid Stem Cell Extracellular Vesicles on Muscle Atrophy and NMJ Integrity. International journal of molecular sciences 24 (5) (2023)
Vincent E Provasek, Manohar Kodavati, Wenting Guo, Haibo Wang, Istvan Boldogh, Ludo Van Den Bosch, Gavin Britz, Muralidhar L Hegde
lncRNA Sequencing Reveals Neurodegeneration-Associated FUS Mutations Alter Transcriptional Landscape of iPS Cells That Persists in Motor Neurons. Cells 12 (20) (2023)
Lise Finotto, Basiel Cole, Wolfgang Giese, Elisabeth Baumann, Annelies Claeys, Maxime Vanmechelen, Brecht Decraene, Marleen Derweduwe, Nikolina Dubroja Lakic, Gautam Shankar, Madhu Nagathihalli Kantharaju, Jan Philipp Albrecht, Ilse Geudens, Fabio Stanchi, Keith L Ligon, Bram Boeckx, Diether Lambrechts, Kyle I S Harrington, Ludo Van Den Bosch, Steven De Vleeschouwer, Frederik De Smet, Holger Gerhardt
Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma. EMBO molecular medicine (2023)
Martina Gatti, Katarina Stoklund Dittlau, Francesca Beretti, Laura Yedigaryan, Manuela Zavatti, Pietro Cortelli, Antonella Sola, Emma Bertucci, Ludo Van Den Bosch, Maurilio Sampaolesi, Tullia Maraldi
Human Neuromuscular Junction on a Chip: Impact of Amniotic Fluid Stem Cell Extracellular Vesicles on Muscle Atrophy and NMJ Integrity. International journal of molecular sciences 24 (5) (2023)
Evelien Van Schoor, Mathieu Vandenbulcke, Valérie Bercier, Rik Vandenberghe, Julie van der Zee, Christine Van Broeckhoven, Markus Otto, Bernard Hanseeuw, Philip Van Damme, Ludo Van Den Bosch, Dietmar Rudolf Thal
Frontotemporal Lobar Degeneration Case with an N-Terminal TUBA4A Mutation Exhibits Reduced TUBA4A Levels in the Brain and TDP-43 Pathology. Biomolecules 12 (3) (2022)
Robert Prior, Stijn Verschoren, Katlijn Vints, Tom Jaspers, Elisabeth Rossaert, Yvonne E Klingl, Alessio Silva, Nicole Hersmus, Philip Van Damme, Ludo Van Den Bosch
HDAC3 Inhibition Stimulates Myelination in a CMT1A Mouse Model. Molecular neurobiology 59 (6) (2022)
Wenting Guo, Haibo Wang, Arun Kumar Tharkeshwar, Julien Couthouis, Elke Braems, Pegah Masrori, Evelien Van Schoor, Yannan Fan, Karan Ahuja, Matthieu Moisse, Maarten Jacquemyn, Rodrigo Furtado Madeiro da Costa, Madhavsai Gajjar, Sriram Balusu, Tine Tricot, Laura Fumagalli, Nicole Hersmus, Rekin's Janky, Francis Impens, Pieter Vanden Berghe, Ritchie Ho, Dietmar Rudolf Thal, Rik Vandenberghe, Muralidhar L Hegde, Siddharthan Chandran, Bart De Strooper, Dirk Daelemans, Philip Van Damme, Ludo Van Den Bosch, Catherine Verfaillie
CRISPR/Cas9 screen in human iPSC-derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity. Alzheimer's & dementia : the journal of the Alzheimer's Association (2022)
Donya Pakravan, Emiel Michiels, Anna Bratek-Skicki, Mathias De Decker, Joris Van Lindt, David Alsteens, Sylvie Derclaye, Philip Van Damme, Joost Schymkowitz, Frederic Rousseau, Peter Tompa, Ludo Van Den Bosch
Liquid-Liquid Phase Separation Enhances TDP-43 LCD Aggregation but Delays Seeded Aggregation. Biomolecules 11 (4) (2021)
Joni Vanneste, Ludo Van Den Bosch
The Role of Nucleocytoplasmic Transport Defects in Amyotrophic Lateral Sclerosis. International journal of molecular sciences 22 (22) (2021)
Laura Fumagalli, Florence L Young, Steven Boeynaems, Mathias De Decker, Arpan R Mehta, Ann Swijsen, Raheem Fazal, Wenting Guo, Matthieu Moisse, Jimmy Beckers, Lieselot Dedeene, Bhuvaneish T Selvaraj, Tijs Vandoorne, Vanesa Madan, Marka van Blitterswijk, Denitza Raitcheva, Alexander McCampbell, Koen Poesen, Aaron D Gitler, Philipp Koch, Pieter Vanden Berghe, Dietmar Rudolf Thal, Catherine M Verfaillie, Siddharthan Chandran, Ludo Van Den Bosch, Simon L Bullock, Philip Van Damme
C9orf72-derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility. Science advances 7 (15) (2021)
Joris Van Lindt, Anna Bratek-Skicki, Phuong N Nguyen, Donya Pakravan, Luis Fernando Durán-Armenta, Agnes Tantos, Rita Pancsa, Ludo Van Den Bosch, Dominique Maes, Peter Tompa
A generic approach to study the kinetics of liquid-liquid phase separation under near-native conditions. Communications biology 4 (1) (2021)
Joris Van Lindt, Anna Bratek-Skicki, Phuong N Nguyen, Donya Pakravan, Luis Fernando Durán-Armenta, Agnes Tantos, Rita Pancsa, Ludo Van Den Bosch, Dominique Maes, Peter Tompa
Author Correction: A generic approach to study the kinetics of liquid-liquid phase separation under near-native conditions. Communications biology 4 (1) (2021)
Thibaut Burg, Elisabeth Rossaert, Matthieu Moisse, Philip Van Damme, Ludo Van Den Bosch
Histone Deacetylase Inhibition Regulates Lipid Homeostasis in a Mouse Model of Amyotrophic Lateral Sclerosis. International journal of molecular sciences 22 (20) (2021)
Paraskevi Tziortzouda, Ludo Van Den Bosch, Frank Hirth
Triad of TDP43 control in neurodegeneration: autoregulation, localization and aggregation. Nature reviews. Neuroscience 22 (4) (2021)
Raheem Fazal, Steven Boeynaems, Ann Swijsen, Mathias De Decker, Laura Fumagalli, Matthieu Moisse, Joni Vanneste, Wenting Guo, Ruben Boon, Thomas Vercruysse, Kristel Eggermont, Bart Swinnen, Jimmy Beckers, Donya Pakravan, Tijs Vandoorne, Pieter Vanden Berghe, Catherine Verfaillie, Ludo Van Den Bosch, Philip Van Damme
HDAC6 inhibition restores TDP-43 pathology and axonal transport defects in human motor neurons with TARDBP mutations. The EMBO journal 40 (7) (2021)
Paraskevi Tziortzouda, Ludo Van Den Bosch, Frank Hirth
Reply to 'TDP43 aggregates: the 'Schrödinger's cat' in amyotrophic lateral sclerosis'. Nature reviews. Neuroscience 22 (8) (2021)
Carlotta Borgarelli, Yvonne E Klingl, Abril Escamilla Ayala, Sebastian Munck, Ludo Van Den Bosch, Wim Michel De Borggraeve, Ermal Ismalaj
Lighting Up the Plasma Membrane: Development and Applications of Fluorescent Ligands for Transmembrane Proteins. Chemistry (Weinheim an der Bergstrasse, Germany) 27 (34) (2021)
Yvonne E Klingl, Donya Pakravan, Ludo Van Den Bosch
Opportunities for histone deacetylase inhibition in amyotrophic lateral sclerosis. British journal of pharmacology 178 (6) (2020)
Bart E K S Swinnen, Wim Robberecht, Ludo Van Den Bosch
RNA toxicity in non-coding repeat expansion disorders. The EMBO journal 39 (1) (2019)
Tijs Vandoorne, Koen Veys, Wenting Guo, Adria Sicart, Katlijn Vints, Ann Swijsen, Matthieu Moisse, Guy Eelen, Natalia V Gounko, Laura Fumagalli, Raheem Fazal, Christine Germeys, Annelies Quaegebeur, Sarah-Maria Fendt, Peter Carmeliet, Catherine Verfaillie, Philip Van Damme, Bart Ghesquière, Katrien De Bock, Ludo Van Den Bosch
Differentiation but not ALS mutations in FUS rewires motor neuron metabolism. Nature communications 10 (1) (2019)
Ludo Van Den Bosch
HDAC6 and Miro1: Another interaction causing trouble in neurons. The Journal of cell biology 218 (6) (2019)
Joni Vanneste, Thomas Vercruysse, Steven Boeynaems, Adria Sicart, Philip Van Damme, Dirk Daelemans, Ludo Van Den Bosch
C9orf72-generated poly-GR and poly-PR do not directly interfere with nucleocytoplasmic transport. Scientific reports 9 (1) (2019)
Wenting Guo, Maximilian Naujock, Laura Fumagalli, Tijs Vandoorne, Pieter Baatsen, Ruben Boon, Laura Ordovás, Abdulsamie Patel, Marc Welters, Thomas Vanwelden, Natasja Geens, Tine Tricot, Veronick Benoy, Jolien Steyaert, Cynthia Lefebvre-Omar, Werend Boesmans, Matthew Jarpe, Jared Sterneckert, Florian Wegner, Susanne Petri, Delphine Bohl, Pieter Vanden Berghe, Wim Robberecht, Philip Van Damme, Catherine M Verfaillie, Ludo Van Den Bosch
HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients. Nature communications 8 (1) (2017)