Aaron D Gitler

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 25

Top Topics

Endoplasmic Reticulum

Amyotrophic Lateral Sclerosis

Transcription Factor

Genome Wide Association Study

Top Venues

bioRxiv : the preprint server for biology

Nature neuroscience

This page only lists publications with an associated author ORCID identifier.

Publications

Yi Zeng, Anastasiia Lovchykova, Tetsuya Akiyama, Chang Liu, Caiwei Guo, Vidhya Maheswari Jawahar, Odilia Sianto, Anna Calliari, Mercedes Prudencio, Gourisankar Ghosh, Leonard Petrucelli, Aaron D Gitler
TDP-43 nuclear loss in FTD/ALS causes widespread alternative polyadenylation changes. bioRxiv : the preprint server for biology (2024)
Caitlin A Taylor, Maya Maor-Nof, Eyal Metzl-Raz, Aaron Hidalgo, Callista Yee, Aaron D Gitler, Kang Shen
Histone deacetylase inhibition expands cellular proteostasis repertoires to enhance neuronal stress resilience. bioRxiv : the preprint server for biology (2024)
Yi Zeng, Anastasiia Lovchykova, Tetsuya Akiyama, Chang Liu, Caiwei Guo, Vidhya Maheswari Jawahar, Odilia Sianto, Anna Calliari, Mercedes Prudencio, Gourisankar Ghosh, Leonard Petrucelli, Aaron D Gitler
TDP-43 nuclear loss in FTD/ALS causes widespread alternative polyadenylation changes. bioRxiv : the preprint server for biology (2024)
Olivia Gautier, Aaron D Gitler
It's me, hi, I solved the problem, it's TF-seqFISH. Cell research 34 (3) (2024)
Olivia Gautier, Aaron D Gitler
It's me, hi, I solved the problem, it's TF-seqFISH. Cell research 34 (3) (2024)
Olivia Gautier, Aaron D Gitler
It's me, hi, I solved the problem, it's TF-seqFISH. Cell research (2024)
Jayson J Smith, Seth R Taylor, Jacob A Blum, Aaron D Gitler, David M Miller, Paschalis Kratsios
A molecular atlas of adult C. elegans motor neurons reveals ancient diversity delineated by conserved transcription factor codes. bioRxiv : the preprint server for biology (2023)
Steven Boeynaems, X Rosa Ma, Vivian Yeong, Garrett M Ginell, Jian-Hua Chen, Jacob A Blum, Lisa Nakayama, Anushka Sanyal, Adam Briner, Delphi Van Haver, Jarne Pauwels, Axel Ekman, Hermann Broder Schmidt, Kousik Sundararajan, Lucas Porta, Keren Lasker, Carolyn A Larabell, Mirian A F Hayashi, Anshul Kundaje, Francis Impens, Allie C Obermeyer, Alex S Holehouse, Aaron D Gitler
Aberrant phase separation is a common killing strategy of positively charged peptides in biology and human disease. bioRxiv : the preprint server for biology (2023)
Lindsey D Goodman, Mercedes Prudencio, Nicholas J Kramer, Luis F Martinez-Ramirez, Ananth R Srinivasan, Matthews Lan, Michael J Parisi, Yongqing Zhu, Jeannie Chew, Casey N Cook, Amit Berson, Aaron D Gitler, Leonard Petrucelli, Nancy M Bonini
Author Correction: Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD. Nature neuroscience (2023)
Keren Lasker, Steven Boeynaems, Vinson Lam, Daniel Scholl, Emma Stainton, Adam Briner, Maarten Jacquemyn, Dirk Daelemans, Ashok Deniz, Elizabeth Villa, Alex S Holehouse, Aaron D Gitler, Lucy Shapiro
The material properties of a bacterial-derived biomolecular condensate tune biological function in natural and synthetic systems. Nature communications 13 (1) (2022)
X Rosa Ma, Mercedes Prudencio, Yuka Koike, Sarat C Vatsavayai, Garam Kim, Fred Harbinski, Adam Briner, Caitlin M Rodriguez, Caiwei Guo, Tetsuya Akiyama, H Broder Schmidt, Beryl B Cummings, David W Wyatt, Katherine Kurylo, Georgiana Miller, Shila Mekhoubad, Nathan Sallee, Gemechu Mekonnen, Laura Ganser, Jack D Rubien, Karen Jansen-West, Casey N Cook, Sarah Pickles, Björn E Oskarsson, Neill R Graff-Radford, Bradley F Boeve, David S Knopman, Ronald C Petersen, Gourisankar Ghosh, James Shorter, Sua Myong, Eric M Green, William W Seeley, Leonard Petrucelli, Aaron D Gitler
TDP-43 represses cryptic exon inclusion in the FTD-ALS gene UNC13A. Nature 603 (7899) (2022)
Laura Fumagalli, Florence L Young, Steven Boeynaems, Mathias De Decker, Arpan R Mehta, Ann Swijsen, Raheem Fazal, Wenting Guo, Matthieu Moisse, Jimmy Beckers, Lieselot Dedeene, Bhuvaneish T Selvaraj, Tijs Vandoorne, Vanesa Madan, Marka van Blitterswijk, Denitza Raitcheva, Alexander McCampbell, Koen Poesen, Aaron D Gitler, Philipp Koch, Pieter Vanden Berghe, Dietmar Rudolf Thal, Catherine M Verfaillie, Siddharthan Chandran, Ludo Van Den Bosch, Simon L Bullock, Philip Van Damme
C9orf72-derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility. Science advances 7 (15) (2021)
Sarah J Eger, Yann Le Guen, Raiyan R Khan, Jacob N Hall, Gabriel Kennedy, Greg Zaharchuk, Julien Couthouis, William S Brooks, Dennis Velakoulis, Valerio Napolioni, Michael E Belloy, Cliffton L Dalgard, Elizabeth C Mormino, Aaron D Gitler, Michael D Greicius
Confirming Pathogenicity of the F386L PSEN1 Variant in a South Asian Family With Early-Onset Alzheimer Disease. Neurology. Genetics 8 (1) (2021)
Jacob A Blum, Sandy Klemm, Jennifer L Shadrach, Kevin A Guttenplan, Lisa Nakayama, Arwa Kathiria, Phuong T Hoang, Olivia Gautier, Julia A Kaltschmidt, William J Greenleaf, Aaron D Gitler
Single-cell transcriptomic analysis of the adult mouse spinal cord reveals molecular diversity of autonomic and skeletal motor neurons. Nature neuroscience 24 (4) (2021)
Kevin A Guttenplan, Maya K Weigel, Priya Prakash, Prageeth R Wijewardhane, Michael R O'Dea, Uriel Rufen-Blanchette, Alexandra E Münch, Jacob A Blum, Jonathan Fine, Mikaela C Neal, Kimberley D Bruce, Aaron D Gitler, Gaurav Chopra, Shane A Liddelow, Ben A Barres
Neurotoxic reactive astrocytes induce cell death via saturated lipids. Nature 599 (7883) (2021)
Rui Tang, Christopher W Murray, Ian L Linde, Nicholas J Kramer, Zhonglin Lyu, Min K Tsai, Leo C Chen, Hongchen Cai, Aaron D Gitler, Edgar G Engleman, Wonjae Lee, Monte M Winslow
A versatile system to record cell-cell interactions. eLife 9 (2020)
Kevin A Guttenplan, Maya K Weigel, Drew I Adler, Julien Couthouis, Shane A Liddelow, Aaron D Gitler, Ben A Barres
Knockout of reactive astrocyte activating factors slows disease progression in an ALS mouse model. Nature communications 11 (1) (2020)
Shizuka B Yamada, Tania F Gendron, Teresa Niccoli, Naomi R Genuth, Rosslyn Grosely, Yingxiao Shi, Idoia Glaria, Nicholas J Kramer, Lisa Nakayama, Shirleen Fang, Tai J I Dinger, Annora Thoeng, Gabriel Rocha, Maria Barna, Joseph D Puglisi, Linda Partridge, Justin K Ichida, Adrian M Isaacs, Leonard Petrucelli, Aaron D Gitler
RPS25 is required for efficient RAN translation of C9orf72 and other neurodegenerative disease-associated nucleotide repeats. Nature neuroscience 22 (9) (2019)
Lindsey D Goodman, Mercedes Prudencio, Nicholas J Kramer, Luis F Martinez-Ramirez, Ananth R Srinivasan, Matthews Lan, Michael J Parisi, Yongqing Zhu, Jeannie Chew, Casey N Cook, Amit Berson, Aaron D Gitler, Leonard Petrucelli, Nancy M Bonini
Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD. Nature neuroscience 22 (6) (2019)
Yong-Jie Zhang, Tania F Gendron, Mark T W Ebbert, Aliesha D O'Raw, Mei Yue, Karen Jansen-West, Xu Zhang, Mercedes Prudencio, Jeannie Chew, Casey N Cook, Lillian M Daughrity, Jimei Tong, Yuping Song, Sarah R Pickles, Monica Castanedes-Casey, Aishe Kurti, Rosa Rademakers, Björn E Oskarsson, Gourisankar Ghosh, Wenqian Hu, Aaron D Gitler, John D Fryer, Leonard Petrucelli
Poly(GR) impairs protein translation and stress granule dynamics in C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis. Nature medicine 24 (8) (2018)
Aaron D Gitler, John D Fryer
A matter of balance. eLife 7 (2018)
Aaron D Gitler, Paraminder Dhillon, James Shorter
Neurodegenerative disease: models, mechanisms, and a new hope. Disease models & mechanisms 10 (5) (2018)
Nicholas J Kramer, Michael S Haney, David W Morgens, Ana Jovičić, Julien Couthouis, Amy Li, James A Ousey, Rosanna K Ma, Gregor Bieri, C Kimberly Tsui, Yingxiao Shi, Nicholas T Hertz, Marc Tessier-Lavigne, Justin K Ichida, Michael C Bassik, Aaron D Gitler
CRISPR-Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity. Nature genetics 50 (4) (2018)
Nicholas J Kramer, Aaron D Gitler
Regrowing axons with alternative splicing. eLife 5 (2016)
Kelly Louise Williams, Simon D Topp, Shu Yang, Bradley Smith, Jennifer A Fifita, Sadaf T Warraich, Katharine Y Zhang, Natalie Farrawell, Caroline Vance, Xun Hu, Alessandra Chesi, Claire S Leblond, Albert Lee, Stephanie L Rayner, Vinod Sundaramoorthy, Carol Dobson-Stone, Mark P Molloy, Marka van Blitterswijk, Gourisankar Ghosh, Ronald C Petersen, Neill R Graff-Radford, Bradley F Boeve, Melissa E Murray, Cyril Pottier, Emily Don, Claire Winnick, Emily P McCann, Alison Hogan, Hussein Daoud, Annie Levert, Patrick A Dion, Jun Mitsui, Hiroyuki Ishiura, Yuji Takahashi, Jun Goto, Jason Kost, Cinzia Gellera, Athina Soragia Gkazi, Jack Miller, Joanne Stockton, William S Brooks, Karyn Boundy, Meraida Polak, José Luis Muñoz-Blanco, Jesús Esteban-Pérez, Alberto Rábano, Orla Hardiman, Karen E Morrison, Nicola Ticozzi, Vincenzo Silani, Jacqueline de Belleroche, Jonathan D Glass, John B J Kwok, Gilles J Guillemin, Roger S Chung, Shoji Tsuji, Robert H Brown, Alberto García-Redondo, Rosa Rademakers, John E Landers, Aaron D Gitler, Guy A Rouleau, Nicholas J Cole, Justin J Yerbury, Julie D Atkin, Christopher E Shaw, Garth A Nicholson, Ian P Blair
CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia. Nature communications 7 (2016)