Philip Van Damme (Philip van Damme, P Van Damme)

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 88

Top Venues

Journal of neurology, neurosurgery, and psychiatry

Autophagy

Amyotrophic lateral sclerosis & frontotemporal degeneration

Acta neuropathologica

University Hospitals Leuven

KU Leuven (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University Hospitals Leuven Jul 01 2013

Belgium

Director of Neuromuscular Reference Center :: Neurology

KU Leuven Oct 01 2009

Belgium

Professor of Neuroscience :: Neuroscience

University Hospitals Leuven Oct 01 2006

Belgium

Neuromuscular specialist :: Neurologist

Education History

KU Leuven Oct 01 2000 - Sep 30 2004

Belgium

PHD :: Neuroscience

Publications

Paraskevi Tziortzouda, Jolien Steyaert, Wendy Scheveneels, Adria Sicart, Katarina Stoklund Dittlau, Adriana Margarida Barbosa Correia, Thibaut Burg, Arun Pal, Andreas Hermann, Philip Van Damme, Thomas G Moens, Ludo Van Den Bosch
PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transport. Acta neuropathologica 147 (1) (2024)
Paraskevi Tziortzouda, Jolien Steyaert, Wendy Scheveneels, Adria Sicart, Katarina Stoklund Dittlau, Adriana Margarida Barbosa Correia, Thibaut Burg, Arun Pal, Andreas Hermann, Philip Van Damme, Thomas G Moens, Ludo Van Den Bosch
PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transport. Acta neuropathologica 147 (1) (2024)
Robert Prior, Alessio Silva, Tim Vangansewinkel, Jakub Idkowiak, Arun Kumar Tharkeshwar, Tom P Hellings, Iliana Michailidou, Jeroen Vreijling, Maarten Loos, Bastijn Koopmans, Nina Vlek, Cedrick Agaser, Thomas B Kuipers, Christine Michiels, Elisabeth Rossaert, Stijn Verschoren, Wendy Vermeire, Vincent de Laat, Jonas Dehairs, Kristel Eggermont, Diede van den Biggelaar, Adekunle T Bademosi, Frederic A Meunier, Martin vandeVen, Philip Van Damme, Hailiang Mei, Johannes V Swinnen, Ivo Lambrichts, Frank Baas, Kees Fluiter, Esther Wolfs, Ludo Van Den Bosch
PMP22 duplication dysregulates lipid homeostasis and plasma membrane organization in developing human Schwann cells. Brain : a journal of neurology 147 (9) (2024)
Paraskevi Tziortzouda, Jolien Steyaert, Wendy Scheveneels, Adria Sicart, Katarina Stoklund Dittlau, Adriana Margarida Barbosa Correia, Thibaut Burg, Arun Pal, Andreas Hermann, Philip Van Damme, Thomas G Moens, Ludo Van Den Bosch
PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transport. Acta neuropathologica 147 (1) (2024)
Stefania Sasso, Lehti Saag, Rachèl Spros, Owyn Beneker, Ludovica Molinaro, Simone Andrea Biagini, Alexander Lehouck, Katrien Van De Vijver, Ruoyun Hui, Eugenia D'Atanasio, Alena Kushniarevich, Helja Kabral, Ene Metspalu, Meriam Guellil, Muhammad Q A Ali, Jan Geypen, Maxim Hoebreckx, Birgit Berk, Natasja De Winter, Petra Driesen, April Pijpelink, Philip Van Damme, Christiana L Scheib, Ewoud Deschepper, Pieterjan Deckers, Christophe Snoeck, Marc Dewilde, Anton Ervynck, Kristiina Tambets, Maarten H D Larmuseau, Toomas Kivisild
Capturing the fusion of two ancestries and kinship structures in Merovingian Flanders. Proceedings of the National Academy of Sciences of the United States of America 121 (27) (2024)
James P K Rooney, Deirdre Murray, Dara Meldrum, Ammar Al Chalabi, Tommy Bunte, Theresa Chiwera, Mutahhara Choudhury, Adriano Chio, Lauren Fenton, Jennifer Fortune, Lindsay Maidment, Umberto Manera, Christopher J McDermott, Myrte Meyjes, Rachel Tattersall, Maria Claudia Torrieri, Philip Van Damme, Elien Vanderlinden, Claire Wood, Leonard H van den Berg, Orla Hardiman
REVEALS-a longitudinal cohort study of multifaceted respiratory assessment in ALS. Amyotrophic lateral sclerosis & frontotemporal degeneration (2024)
Jimmy Beckers, Philip Van Damme
Toxic gain-of-function mechanisms in C9orf72 ALS-FTD neurons drive autophagy and lysosome dysfunction. Autophagy 20 (9) (2024)
Stefania Sasso, Lehti Saag, Rachèl Spros, Owyn Beneker, Ludovica Molinaro, Simone Andrea Biagini, Alexander Lehouck, Katrien Van De Vijver, Ruoyun Hui, Eugenia D'Atanasio, Alena Kushniarevich, Helja Kabral, Ene Metspalu, Meriam Guellil, Muhammad Q A Ali, Jan Geypen, Maxim Hoebreckx, Birgit Berk, Natasja De Winter, Petra Driesen, April Pijpelink, Philip Van Damme, Christiana L Scheib, Ewoud Deschepper, Pieterjan Deckers, Christophe Snoeck, Marc Dewilde, Anton Ervynck, Kristiina Tambets, Maarten H D Larmuseau, Toomas Kivisild
Capturing the fusion of two ancestries and kinship structures in Merovingian Flanders. Proceedings of the National Academy of Sciences of the United States of America 121 (27) (2024)
Philip Van Damme, Ammar Al Chalabi, Peter M Andersen, Adriano Chio, Philippe Couratier, Mamede de Carvalho, Orla Hardiman, Magdalena Kuzma-Kozakiewicz, Albert Ludolph, Christopher J McDermott, Jesus S Mora, Susanne Petri, Katrin Probyn, Evy Reviers, François Salachas, Vincenzo Silani, Ole-Bjørn Tysnes, Leonard H van den Berg, Gemma Villanueva, Markus Weber
European Academy of Neurology (EAN) guideline on the management of amyotrophic lateral sclerosis in collaboration with European Reference Network for Neuromuscular Diseases (ERN EURO-NMD). European journal of neurology 31 (6) (2024)
Paraskevi Tziortzouda, Jolien Steyaert, Wendy Scheveneels, Adria Sicart, Katarina Stoklund Dittlau, Adriana Margarida Barbosa Correia, Thibaut Burg, Arun Pal, Andreas Hermann, Philip Van Damme, Thomas G Moens, Ludo Van Den Bosch
PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transport. Acta neuropathologica 147 (1) (2024)
Jimmy Beckers, Philip Van Damme
Toxic gain-of-function mechanisms in C9orf72 ALS-FTD neurons drive autophagy and lysosome dysfunction. Autophagy (2024)
Jimmy Beckers, Philip Van Damme
Toxic gain-of-function mechanisms in C9orf72 ALS-FTD neurons drive autophagy and lysosome dysfunction. Autophagy 20 (9) (2024)
Philip Van Damme, Ammar Al Chalabi, Peter M Andersen, Adriano Chio, Philippe Couratier, Mamede de Carvalho, Orla Hardiman, Magdalena Kuzma-Kozakiewicz, Albert Ludolph, Christopher J McDermott, Jesus S Mora, Susanne Petri, Katrin Probyn, Evy Reviers, François Salachas, Vincenzo Silani, Ole-Bjørn Tysnes, Leonard H van den Berg, Gemma Villanueva, Markus Weber
European Academy of Neurology (EAN) guideline on the management of amyotrophic lateral sclerosis in collaboration with European Reference Network for Neuromuscular Diseases (ERN EURO-NMD). European journal of neurology 31 (6) (2024)
Stefania Sasso, Lehti Saag, Rachèl Spros, Owyn Beneker, Ludovica Molinaro, Simone Andrea Biagini, Alexander Lehouck, Katrien Van De Vijver, Ruoyun Hui, Eugenia D'Atanasio, Alena Kushniarevich, Helja Kabral, Ene Metspalu, Meriam Guellil, Muhammad Q A Ali, Jan Geypen, Maxim Hoebreckx, Birgit Berk, Natasja De Winter, Petra Driesen, April Pijpelink, Philip Van Damme, Christiana L Scheib, Ewoud Deschepper, Pieterjan Deckers, Christophe Snoeck, Marc Dewilde, Anton Ervynck, Kristiina Tambets, Maarten H D Larmuseau, Toomas Kivisild
Capturing the fusion of two ancestries and kinship structures in Merovingian Flanders. Proceedings of the National Academy of Sciences of the United States of America 121 (27) (2024)
Jimmy Beckers, Philip Van Damme
Toxic gain-of-function mechanisms in C9orf72 ALS-FTD neurons drive autophagy and lysosome dysfunction. Autophagy 20 (9) (2024)
Jimmy Beckers, Philip Van Damme
Toxic gain-of-function mechanisms in C9orf72 ALS-FTD neurons drive autophagy and lysosome dysfunction. Autophagy 20 (9) (2024)
Paraskevi Tziortzouda, Jolien Steyaert, Wendy Scheveneels, Adria Sicart, Katarina Stoklund Dittlau, Adriana Margarida Barbosa Correia, Thibaut Burg, Arun Pal, Andreas Hermann, Philip Van Damme, Thomas G Moens, Ludo Van Den Bosch
PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transport. Acta neuropathologica 147 (1) (2024)
Heather Marriott, Thomas P Spargo, Ahmad Al Khleifat, Peter M Andersen, Ayse Nazli Basak, Johnathan Cooper-Knock, Philippe Corcia, Philippe Couratier, Mamede de Carvalho, Vivian Drory, Marc Gotkine, John E Landers, Russell McLaughlin, Jesús S Mora Pardina, Karen E Morrison, Susana Pinto, Christopher E Shaw, Pamela J Shaw, Vincenzo Silani, Nicola Ticozzi, Philip Van Damme, Leonard H van den Berg, Patrick Vourc'h, Markus Weber, Jan H Veldink, null null, Richard J Dobson, Patrick Schwab, Ammar Al Chalabi, Alfredo Iacoangeli
Mutations in the tail and rod domains of the neurofilament heavy-chain gene increase the risk of ALS. Annals of clinical and translational neurology 11 (7) (2024)
Heather Marriott, Thomas P Spargo, Ahmad Al Khleifat, Peter M Andersen, Ayse Nazli Basak, Johnathan Cooper-Knock, Philippe Corcia, Philippe Couratier, Mamede de Carvalho, Vivian Drory, Marc Gotkine, John E Landers, Russell McLaughlin, Jesús S Mora Pardina, Karen E Morrison, Susana Pinto, Christopher E Shaw, Pamela J Shaw, Vincenzo Silani, Nicola Ticozzi, Philip Van Damme, Leonard H van den Berg, Patrick Vourc'h, Markus Weber, Jan H Veldink, null null, Richard J Dobson, Patrick Schwab, Ammar Al Chalabi, Alfredo Iacoangeli
Mutations in the tail and rod domains of the neurofilament heavy-chain gene increase the risk of ALS. Annals of clinical and translational neurology 11 (7) (2024)
Jimmy Beckers, Philip Van Damme
Toxic gain-of-function mechanisms in C9orf72 ALS-FTD neurons drive autophagy and lysosome dysfunction. Autophagy (2024)
Philip Van Damme, Ammar Al Chalabi, Peter M Andersen, Adriano Chio, Philippe Couratier, Mamede de Carvalho, Orla Hardiman, Magdalena Kuzma-Kozakiewicz, Albert Ludolph, Christopher J McDermott, Jesus S Mora, Susanne Petri, Katrin Probyn, Evy Reviers, François Salachas, Vincenzo Silani, Ole-Bjørn Tysnes, Leonard H van den Berg, Gemma Villanueva, Markus Weber
European Academy of Neurology (EAN) guideline on the management of amyotrophic lateral sclerosis in collaboration with European Reference Network for Neuromuscular Diseases (ERN EURO-NMD). European journal of neurology (2024)
Philip Van Damme, Ammar Al Chalabi, Peter M Andersen, Adriano Chio, Philippe Couratier, Mamede de Carvalho, Orla Hardiman, Magdalena Kuzma-Kozakiewicz, Albert Ludolph, Christopher J McDermott, Jesus S Mora, Susanne Petri, Katrin Probyn, Evy Reviers, François Salachas, Vincenzo Silani, Ole-Bjørn Tysnes, Leonard H van den Berg, Gemma Villanueva, Markus Weber
European Academy of Neurology (EAN) guideline on the management of amyotrophic lateral sclerosis in collaboration with European Reference Network for Neuromuscular Diseases (ERN EURO-NMD). European journal of neurology 31 (6) (2024)
Robert Prior, Alessio Silva, Tim Vangansewinkel, Jakub Idkowiak, Arun Kumar Tharkeshwar, Tom P Hellings, Iliana Michailidou, Jeroen Vreijling, Maarten Loos, Bastijn Koopmans, Nina Vlek, Cedrick Agaser, Thomas B Kuipers, Christine Michiels, Elisabeth Rossaert, Stijn Verschoren, Wendy Vermeire, Vincent de Laat, Jonas Dehairs, Kristel Eggermont, Diede van den Biggelaar, Adekunle T Bademosi, Frederic A Meunier, Martin vandeVen, Philip Van Damme, Hailiang Mei, Johannes V Swinnen, Ivo Lambrichts, Frank Baas, Kees Fluiter, Esther Wolfs, Ludo Van Den Bosch
PMP22 duplication dysregulates lipid homeostasis and plasma membrane organization in developing human Schwann cells. Brain : a journal of neurology (2024)
Sarah Opie-Martin, Alfredo Iacoangeli, Simon D Topp, Olubunmi Abel, Keith Mayl, Puja R Mehta, Aleksey Shatunov, Isabella Fogh, Harry Bowles, Naomi Limbachiya, Thomas P Spargo, Ahmad Al Khleifat, Kelly Louise Williams, Jennifer Jockel-Balsarotti, Taha Bali, Wade K Self, Lyndal Henden, Garth A Nicholson, Nicola Ticozzi, Diane McKenna-Yasek, Lu Tang, Dame Pamela J Shaw, Adriano Chio, Albert Ludolph, Jochen H Weishaupt, John E Landers, Jonathan D Glass, Jesus S Mora, Wim Robberecht, Philip Van Damme, Russell Lewis McLaughlin, Orla Hardiman, Leonard van den Berg, Jan Herman Veldink, Phillippe Corcia, Zorica Stevic, Nailah Siddique, Vincenzo Silani, Ian P Blair, Dong-Sheng Fan, Florence Esselin, Elisa de la Cruz, William Camu, Nazli A Basak, Teepu Siddique, Timothy Miller, Robert H Brown, Ammar Al Chalabi, Christopher E Shaw
Author Correction: The SOD1-mediated ALS phenotype shows a decoupling between age of symptom onset and disease duration. Nature communications 15 (1) (2024)
Jimmy Beckers, Philip Van Damme
Toxic gain-of-function mechanisms in C9orf72 ALS-FTD neurons drive autophagy and lysosome dysfunction. Autophagy (2024)
Heather Marriott, Thomas P Spargo, Ahmad Al Khleifat, Peter M Andersen, Ayse Nazli Basak, Johnathan Cooper-Knock, Philippe Corcia, Philippe Couratier, Mamede de Carvalho, Vivian Drory, Marc Gotkine, John E Landers, Russell McLaughlin, Jesús S Mora Pardina, Karen E Morrison, Susana Pinto, Christopher E Shaw, Pamela J Shaw, Vincenzo Silani, Nicola Ticozzi, Philip Van Damme, Leonard H van den Berg, Patrick Vourc'h, Markus Weber, Jan H Veldink, null null, Richard J Dobson, Patrick Schwab, Ammar Al Chalabi, Alfredo Iacoangeli
Mutations in the tail and rod domains of the neurofilament heavy-chain gene increase the risk of ALS. Annals of clinical and translational neurology (2024)
Sarah Opie-Martin, Alfredo Iacoangeli, Simon D Topp, Olubunmi Abel, Keith Mayl, Puja R Mehta, Aleksey Shatunov, Isabella Fogh, Harry Bowles, Naomi Limbachiya, Thomas P Spargo, Ahmad Al Khleifat, Kelly Louise Williams, Jennifer Jockel-Balsarotti, Taha Bali, Wade K Self, Lyndal Henden, Garth A Nicholson, Nicola Ticozzi, Diane McKenna-Yasek, Lu Tang, Dame Pamela J Shaw, Adriano Chio, Albert Ludolph, Jochen H Weishaupt, John E Landers, Jonathan D Glass, Jesus S Mora, Wim Robberecht, Philip Van Damme, Russell Lewis McLaughlin, Orla Hardiman, Leonard van den Berg, Jan Herman Veldink, Phillippe Corcia, Zorica Stevic, Nailah Siddique, Vincenzo Silani, Ian P Blair, Dong-Sheng Fan, Florence Esselin, Elisa de la Cruz, William Camu, Nazli A Basak, Teepu Siddique, Timothy Miller, Robert H Brown, Ammar Al Chalabi, Christopher E Shaw
Author Correction: The SOD1-mediated ALS phenotype shows a decoupling between age of symptom onset and disease duration. Nature communications 15 (1) (2024)
Heather Marriott, Thomas P Spargo, Ahmad Al Khleifat, Peter M Andersen, Ayse Nazli Basak, Johnathan Cooper-Knock, Philippe Corcia, Philippe Couratier, Mamede de Carvalho, Vivian Drory, Marc Gotkine, John E Landers, Russell McLaughlin, Jesús S Mora Pardina, Karen E Morrison, Susana Pinto, Christopher E Shaw, Pamela J Shaw, Vincenzo Silani, Nicola Ticozzi, Philip Van Damme, Leonard H van den Berg, Patrick Vourc'h, Markus Weber, Jan H Veldink, null null, Richard J Dobson, Patrick Schwab, Ammar Al Chalabi, Alfredo Iacoangeli
Mutations in the tail and rod domains of the neurofilament heavy-chain gene increase the risk of ALS. Annals of clinical and translational neurology 11 (7) (2024)
Joke De Vocht, Donatienne Van Weehaeghe, Fouke Ombelet, Pegah Masrori, Nikita Lamaire, Martijn Devrome, Hilde Van Esch, Mathieu Moisse, Michel Koole, Patrick Dupont, Koen Van Laere, Philip Van Damme
Differences in Cerebral Glucose Metabolism in ALS Patients with and without C9orf72 and SOD1 Mutations. Cells 12 (6) (2023)
Joke De Vocht, Donatienne Van Weehaeghe, Fouke Ombelet, Pegah Masrori, Nikita Lamaire, Martijn Devrome, Hilde Van Esch, Mathieu Moisse, Michel Koole, Patrick Dupont, Koen Van Laere, Philip Van Damme
Differences in Cerebral Glucose Metabolism in ALS Patients with and without C9orf72 and SOD1 Mutations. Cells 12 (6) (2023)
Sien Hilde Van Daele, Matthieu Moisse, Joke J F A van Vugt, Ramona A J Zwamborn, Rick van der Spek, Wouter van Rheenen, Kristel Van Eijk, Kevin Kenna, Philippe Corcia, Patrick Vourc'h, Philippe Couratier, Orla Hardiman, Russell Lewis McLaughlin, Marc Gotkine, Vivian Drory, Nicola Ticozzi, Vincenzo Silani, Antonia Ratti, Mamede de Carvalho, Jesús S Mora Pardina, Monica Povedano, Peter M Andersen, Markus Weber, Nazli A Başak, Chris Shaw, Dame Pamela J Shaw, Karen E Morrison, John E Landers, Jonathan D Glass, Michael A Van Es, Leonard H van den Berg, Ammar Al Chalabi, Jan Veldink, Philip Van Damme
Genetic variability in sporadic amyotrophic lateral sclerosis. Brain : a journal of neurology (2023)
Katarina Stoklund Dittlau, Lisanne Terrie, Pieter Baatsen, Axelle Kerstens, Lim De Swert, Rekin's Janky, Nikky Corthout, Pegah Masrori, Philip Van Damme, Poul Hyttel, Morten Meyer, Lieven Thorrez, Kristine Karla Freude, Ludo Van Den Bosch
FUS-ALS hiPSC-derived astrocytes impair human motor units through both gain-of-toxicity and loss-of-support mechanisms. Molecular neurodegeneration 18 (1) (2023)
Alberto Catanese, Sandeep Rajkumar, Daniel Sommer, Pegah Masrori, Nicole Hersmus, Philip Van Damme, Simon Witzel, Albert Ludolph, Ritchie Ho, Tobias M Boeckers, Medhanie Mulaw
Multiomics and machine-learning identify novel transcriptional and mutational signatures in amyotrophic lateral sclerosis. Brain : a journal of neurology (2023)
Katarina Stoklund Dittlau, Lisanne Terrie, Pieter Baatsen, Axelle Kerstens, Lim De Swert, Rekin's Janky, Nikky Corthout, Pegah Masrori, Philip Van Damme, Poul Hyttel, Morten Meyer, Lieven Thorrez, Kristine Karla Freude, Ludo Van Den Bosch
FUS-ALS hiPSC-derived astrocytes impair human motor units through both gain-of-toxicity and loss-of-support mechanisms. Molecular neurodegeneration 18 (1) (2023)
Jimmy Beckers, Arun Kumar Tharkeshwar, Laura Fumagalli, Matilde Contardo, Evelien Van Schoor, Raheem Fazal, Dietmar Rudolf Thal, Siddharthan Chandran, Renzo Mancuso, Ludo Van Den Bosch, Philip Van Damme
A toxic gain-of-function mechanism in C9orf72 ALS impairs the autophagy-lysosome pathway in neurons. Acta neuropathologica communications 11 (1) (2023)
Katarina Stoklund Dittlau, Lisanne Terrie, Pieter Baatsen, Axelle Kerstens, Lim De Swert, Rekin's Janky, Nikky Corthout, Pegah Masrori, Philip Van Damme, Poul Hyttel, Morten Meyer, Lieven Thorrez, Kristine Karla Freude, Ludo Van Den Bosch
FUS-ALS hiPSC-derived astrocytes impair human motor units through both gain-of-toxicity and loss-of-support mechanisms. Molecular neurodegeneration 18 (1) (2023)
Sean W Willemse, Peter Harley, Ruben P A van Eijk, Koen C Demaegd, Pavol Zelina, R Jeroen Pasterkamp, Philip Van Damme, Caroline Ingre, Wouter van Rheenen, Jan Herman Veldink, Matthew C Kiernan, Ammar Al Chalabi, Leonard H van den Berg, Pietro Fratta, Michael A van Es
UNC13A in amyotrophic lateral sclerosis: from genetic association to therapeutic target. Journal of neurology, neurosurgery, and psychiatry (2023)
Sean W Willemse, Peter Harley, Ruben P A van Eijk, Koen C Demaegd, Pavol Zelina, R Jeroen Pasterkamp, Philip Van Damme, Caroline Ingre, Wouter van Rheenen, Jan Herman Veldink, Matthew C Kiernan, Ammar Al Chalabi, Leonard H van den Berg, Pietro Fratta, Michael A van Es
UNC13A in amyotrophic lateral sclerosis: from genetic association to therapeutic target. Journal of neurology, neurosurgery, and psychiatry (2023)
Sean W Willemse, Peter Harley, Ruben P A van Eijk, Koen C Demaegd, Pavol Zelina, R Jeroen Pasterkamp, Philip Van Damme, Caroline Ingre, Wouter van Rheenen, Jan Herman Veldink, Matthew C Kiernan, Ammar Al Chalabi, Leonard H van den Berg, Pietro Fratta, Michael A van Es
UNC13A in amyotrophic lateral sclerosis: from genetic association to therapeutic target. Journal of neurology, neurosurgery, and psychiatry (2023)
Joke De Vocht, Donatienne Van Weehaeghe, Fouke Ombelet, Pegah Masrori, Nikita Lamaire, Martijn Devrome, Hilde Van Esch, Mathieu Moisse, Michel Koole, Patrick Dupont, Koen Van Laere, Philip Van Damme
Differences in Cerebral Glucose Metabolism in ALS Patients with and without C9orf72 and SOD1 Mutations. Cells 12 (6) (2023)
Katarina Stoklund Dittlau, Lisanne Terrie, Pieter Baatsen, Axelle Kerstens, Lim De Swert, Rekin's Janky, Nikky Corthout, Pegah Masrori, Philip Van Damme, Poul Hyttel, Morten Meyer, Lieven Thorrez, Kristine Karla Freude, Ludo Van Den Bosch
FUS-ALS hiPSC-derived astrocytes impair human motor units through both gain-of-toxicity and loss-of-support mechanisms. Molecular neurodegeneration 18 (1) (2023)
Joris Godelaine, Yamini Chitale, Bart De Moor, Chantal Mathieu, Lina Ancheva, Philip Van Damme, Kristl G Claeys, Xavier Bossuyt, Sebastien Carpentier, Koen Poesen
Peptides From the Variable Domain of Immunoglobulin G as Biomarkers in Chronic Inflammatory Demyelinating Polyradiculoneuropathy. Neurology(R) neuroimmunology & neuroinflammation 10 (6) (2023)
Chen Eitan, Aviad Siany, Elad Barkan, Tsviya Olender, Kristel R van Eijk, Matthieu Moisse, Sali M K Farhan, Yehuda M Danino, Eran Yanowski, Hagai Marmor-Kollet, Natalia Rivkin, Nancy Sarah Yacovzada, Shu-Ting Hung, Johnathan Cooper-Knock, Chien-Hsiung Yu, Cynthia Louis, Seth L Masters, Kevin P Kenna, Rick A A van der Spek, William Sproviero, Ahmad Al Khleifat, Alfredo Iacoangeli, Aleksey Shatunov, Ashley R Jones, Yael Elbaz-Alon, Yahel Cohen, Elik Chapnik, Daphna Rothschild, Omer Weissbrod, Gilad Beck, Elena Ainbinder, Shifra Ben-Dor, Sebastian Werneburg, Dorothy P Schafer, Robert H Brown, Pamela J Shaw, Philip Van Damme, Leonard H van den Berg, Hemali Phatnani, Eran Segal, Justin K Ichida, Ammar Al Chalabi, Jan Herman Veldink, null null, null null, Eran Hornstein
Whole-genome sequencing reveals that variants in the Interleukin 18 Receptor Accessory Protein 3'UTR protect against ALS. Nature neuroscience 25 (4) (2022)
Tessa Kliest, Ruben P A Van Eijk, Ammar Al Chalabi, Alberto Albanese, Peter M Andersen, Maria Del Mar Amador, Geir BrÅthen, Veronique Brunaud-Danel, Lev Brylev, William Camu, Mamede de Carvalho, Cristina Cereda, Hakan Cetin, Delia Chaverri, Adriano Chio, Philippe Corcia, Philippe Couratier, Fabiola De Marchi, Claude Desnuelle, Michael A Van Es, JesÚs Esteban, Massimiliano Mirabella, Alberto GarcÍa Redondo, Julian Grosskreutz, Clemens O Hanemann, Trygve HolmØy, Helle HØyer, Caroline Ingre, Blaz Koritnik, Magdalena Kuzma-Kozakiewicz, Thomas Lambert, Peter N Leigh, Christian Lunetta, Jessica Mandrioli, Christopher J McDermott, Thomas Meyer, Jesus S Mora, Susanne Petri, MÓnica Povedano, Evy Reviers, Nilo Riva, Kit C B Roes, Miguel Á Rubio, FranÇois Salachas, Stayko Sarafov, Gianni SorarÙ, Zorica Stevic, Kirsten Svenstrup, Anette Torvin MØller, Matthew C Kiernan, Philip Van Damme, Lucie A G Van Leeuwen, Luis Varona, Juan Francisco Vázquez Costa, Markus Weber, Orla Hardiman, Leonard H Van Den Berg
Clinical trials in pediatric ALS: a TRICALS feasibility study. Amyotrophic lateral sclerosis & frontotemporal degeneration 23 (7-8) (2022)
Mazen M Dimachkie, Richard J Barohn, Barry Byrne, Ozlem Goker-Alpan, Priya S Kishnani, Shafeeq Ladha, Pascal Laforêt, Karl Eugen Mengel, Loren D M Peña, Sabrina Sacconi, Volker Straub, Jaya Trivedi, Philip Van Damme, Ans T van der Ploeg, John Vissing, Peter Young, Kristina An Haack, Meredith Foster, Jane M Gilbert, Patrick Miossec, Olivier Vitse, Tianyue Zhou, Benedikt Schoser, null null
Long-term Safety and Efficacy of Avalglucosidase Alfa in Patients With Late-Onset Pompe Disease. Neurology (2022)
Julien Barc, Rafik Tadros, Charlotte Glinge, David Y Chiang, Mariam Jouni, Floriane Simonet, Sean Joseph Jurgens, Manon Baudic, Michele Nicastro, Franck Potet, Joost A Offerhaus, Roddy Walsh, Seung Hoan Choi, Arjan C Houweling, Yuka Mizusawa, Soraya Anys, Damien Minois, Marine Arnaud, Josselin Duchateau, Yanushi D Wijeyeratne, Alison Muir, Michael Papadakis, Silvia Castelletti, Margherita Torchio, Cristina Gil Ortuño, Javier Lacunza, Daniela Francesca Giachino, Natascia Cerrato, Raphaël P Martins, Òscar Campuzano, Sonia Van Dooren, Aurélie Thollet, Florence Kyndt, Andrea Mazzanti, Nicolas Clémenty, Arnaud Bisson, Anniek Corveleyn, Birgit Stallmeyer, Sven Dittmann, Johan Saenen, Antoine Noël, Shohreh Honarbakhsh, Boris Rudic, Halim Marzak, Matthew K Rowe, Claire Federspiel, Sophie Le Page, Leslie Placide, Antoine Milhem, Hector Barajas-Martinez, Britt-Maria Beckmann, Ingrid P Krapels, Johannes Steinfurt, Bo Gregers Winkel, Reza Jabbari, Moore B Shoemaker, Bas J Boukens, Doris Škorić-Milosavljević, Hennie Bikker, Federico Manevy, Peter Lichtner, Marta Ribasés, Thomas Meitinger, Martina Müller-Nuraysid, null null, Jan Herman Veldink, Leonard H van den Berg, Philip Van Damme, Daniele Cusi, Chiara Lanzani, Sidwell Rigade, Eric Charpentier, Estelle Baron, Stéphanie Bonnaud, Simon Lecointe, Audrey Donnart, Hervé Le Marec, Stéphanie Chatel, Matilde Karakachoff, Stephane Bezieau, Barry London, Jacob Tfelt-Hansen, Dan Roden, Katja E Odening, Marina Cerrone, Larry A Chinitz, Paul G Volders, Maarten P van den Berg, Gabriel Laurent, Laurence Faivre, Charles Antzelevitch, Stefan Kääb, Alain Al Arnaout, Jean-Marc Dupuis, Jean-Luc Pasquie, Olivier Billon, Jason D Roberts, Laurence Jesel, Martin Borggrefe, Pier D Lambiase, Jacques Mansourati, Bart Loeys, Antoine Leenhardt, Pascale Guicheney, Philippe Maury, Eric Schulze-Bahr, Tomas Robyns, Jeroen Breckpot, Dominique Babuty, Silvia G Priori, Carlo Napolitano, null null, Carlos De Asmundis, Pedro Brugada, Ramon Brugada, Elena Arbelo, Josep Brugada, Philippe Mabo, Nathalie Behar, Carla Giustetto, Maria Sabater Molina, Juan R Gimeno, Can Hasdemir, Peter J Schwartz, Lia Crotti, Pascal P McKeown, Sanjay Sharma, Elijah R Behr, Michel Haissaguerre, Frédéric Sacher, Caroline Rooryck, Hanno L Tan, Carol A Remme, Pieter G Postema, Mario Delmar, Patrick T Ellinor, Steven A Lubitz, Jean-Baptiste Gourraud, Michael W T Tanck, Alfred L George, Calum A MacRae, Maged M Costantine, Christian Dina, Vincent Probst, Arthur A Wilde, Jean-Jacques Schott, Richard Redon, Connie R Bezzina
Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility. Nature genetics 54 (3) (2022)
Sarah Opie-Martin, Alfredo Iacoangeli, Simon D Topp, Olubunmi Abel, Keith Mayl, Puja R Mehta, Aleksey Shatunov, Isabella Fogh, Harry Bowles, Naomi Limbachiya, Thomas P Spargo, Ahmad Al Khleifat, Kelly Louise Williams, Jennifer Jockel-Balsarotti, Taha Bali, Wade K Self, Lyndal Henden, Garth A Nicholson, Nicola Ticozzi, Diane McKenna-Yasek, Lu Tang, Dame Pamela J Shaw, Adriano Chio, Albert Ludolph, Jochen H Weishaupt, John E Landers, Jonathan D Glass, Jesus S Mora, Wim Robberecht, Philip Van Damme, Russell Lewis McLaughlin, Orla Hardiman, Leonard van den Berg, Jan Herman Veldink, Phillippe Corcia, Zorica Stevic, Nailah Siddique, Vincenzo Silani, Ian P Blair, Dong-Sheng Fan, Florence Esselin, Elisa de la Cruz, William Camu, Nazli A Basak, Teepu Siddique, Timothy Miller, Robert H Brown, Ammar Al Chalabi, Christopher E Shaw
The SOD1-mediated ALS phenotype shows a decoupling between age of symptom onset and disease duration. Nature communications 13 (1) (2022)
Paul J Hop, Ramona A J Zwamborn, Eilis J Hannon, Gemma L Shireby, Marta F Nabais, Emma M Walker, Wouter Van Rheenen, Joke J F A van Vugt, Annelot M Dekker, Henk-Jan Westeneng, Gijs H P Tazelaar, Kristel R van Eijk, Matthieu Moisse, Denis Baird, Ahmad Al Khleifat, Alfredo Iacoangeli, Nicola Ticozzi, Antonia Ratti, Johnathan Cooper-Knock, Karen E Morrison, Dame Pamela J Shaw, Ayse Nazli Basak, Adriano Chio, Andrea Calvo, Cristina Moglia, Antonio Canosa, Maura Brunetti, Maurizio Grassano, Marc Gotkine, Yossef Lerner, Michal Zabari, Patrick Vourc'h, Philippe Corcia, Philippe Couratier, Jesus S Mora, Teresa Salas, Patrick Dion, Jay P Ross, Robert David Henderson, Susan Mathers, Pamela A McCombe, Merrilee Needham, Garth Nicholson, Dominic B Rowe, Roger Pamphlett, Karen A Mather, Perminder Singh Sachdev, Sarah Furlong, Fleur C Garton, Anjali K Henders, Tian Lin, Shyuan T Ngo, Frederik J Steyn, Leanne Wallace, Kelly Louise Williams, null null, null null, Miguel Mitne Neto, Ruben J Cauchi, Ian P Blair, Matthew C Kiernan, Vivian Drory, Monica Povedano, Mamede de Carvalho, Susana Pinto, Markus Weber, Guy A Rouleau, Vincenzo Silani, John E Landers, Christopher E Shaw, Peter Munch Andersen, Allan F McRae, Michael A van Es, R Jeroen Pasterkamp, Naomi R Wray, Russell Lewis McLaughlin, Orla Hardiman, Kevin P Kenna, Ellen A Tsai, Heiko Runz, Ammar Al Chalabi, Leonard H van den Berg, Philip Van Damme, Jonathan S Mill, Jan Herman Veldink
Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS. Science translational medicine 14 (633) (2022)
Rose Bruffaerts, Dorothy Gors, Alicia Bárcenas Gallardo, Mathieu Vandenbulcke, Philip Van Damme, Paul Suetens, John C van Swieten, Barbara Borroni, Raquel Sanchez-Valle, Fermin Moreno, Robert Laforce, Caroline Graff, Matthis Synofzik, Daniela Galimberti, James B Rowe, Mario Masellis, Maria Carmela Tartaglia, Elizabeth Finger, Alexandre de Mendonça, Fabrizio Tagliavini, Chris R Butler, Isabel Santana, Alexander Gerhard, Simon Ducharme, Johannes Levin, Adrian Danek, Markus Otto, Jonathan D Rohrer, Patrick Dupont, Peter Claes, Rik Vandenberghe, null null
Hierarchical spectral clustering reveals brain size and shape changes in asymptomatic carriers of C9orf72 . Brain communications 4 (4) (2022)
Robert Prior, Stijn Verschoren, Katlijn Vints, Tom Jaspers, Elisabeth Rossaert, Yvonne E Klingl, Alessio Silva, Nicole Hersmus, Philip Van Damme, Ludo Van Den Bosch
HDAC3 Inhibition Stimulates Myelination in a CMT1A Mouse Model. Molecular neurobiology 59 (6) (2022)
Wouter Leemans, Sofie Antonis, Wouter De Vooght, Robin Lemmens, Philip Van Damme
Neuromuscular complications after COVID-19 vaccination: a series of eight patients. Acta neurologica Belgica 122 (3) (2022)
Maxim De Schaepdryver, Pegah Masrori, Philip Van Damme, Koen Poesen
Effect of neurofilament analysis on the diagnostic delay in amyotrophic lateral sclerosis. CNS neuroscience & therapeutics (2022)
Kristiana Salmon, Matthew C Kiernan, Seung Hyun Kim, Peter Munch Andersen, Adriano Chio, Leonard H van den Berg, Philip Van Damme, Ammar Al Chalabi, Patricia Lillo, Jinsy A Andrews, Angela Genge
The importance of offering early genetic testing in everyone with amyotrophic lateral sclerosis. Brain : a journal of neurology 145 (4) (2022)
Ahmad Al Khleifat, Alfredo Iacoangeli, Joke J F A van Vugt, Harry Bowles, Matthieu Moisse, Ramona A J Zwamborn, Rick A A van der Spek, Aleksey Shatunov, Johnathan Cooper-Knock, Simon Topp, Ross P Byrne, Cinzia Gellera, Victoria López, Ashley R Jones, Sarah Opie-Martin, Atay Vural, Yolanda Campos, Wouter Van Rheenen, Brendan Kenna, Kristel R Van Eijk, Kevin Kenna, Markus Weber, Bradley Smith, Isabella Fogh, Vincenzo Silani, Karen E Morrison, Richard James Butler Dobson, Michael A Van Es, Russell Lewis McLaughlin, Patrick Vourc'h, Adriano Chio, Philippe Corcia, Mamede de Carvalho, Marc Gotkine, Monica P Panades, Jesus S Mora, Pamela J Shaw, John E Landers, Jonathan D Glass, Christopher E Shaw, Nazli Basak, Orla Hardiman, Wim Robberecht, Philip Van Damme, Leonard H van den Berg, Jan Herman Veldink, Ammar Al Chalabi
Structural variation analysis of 6,500 whole genome sequences in amyotrophic lateral sclerosis. NPJ genomic medicine 7 (1) (2022)
Adriaan D de Jongh, Nathalie Braun, Markus Weber, Michael A van Es, Pegah Masrori, Jan Herman Veldink, Philip Van Damme, Leonard H van den Berg, Ruben P A van Eijk
Characterising ALS disease progression according to El Escorial and Gold Coast criteria. Journal of neurology, neurosurgery, and psychiatry 93 (8) (2022)
Joni Vanneste, Thomas Vercruysse, Steven Boeynaems, Philip Van Damme, Dirk Daelemans, Ludo Van Den Bosch
Cellular Stress Induces Nucleocytoplasmic Transport Deficits Independent of Stress Granules. Biomedicines 10 (5) (2022)
Matthieu Moisse, Ramona A J Zwamborn, Joke J F A van Vugt, Rick A A van der Spek, Wouter Van Rheenen, Brendan Kenna, Kristel Van Eijk, Kevin Kenna, Philippe Corcia, Philippe Couratier, Patrick Vourc'h, Orla Hardiman, Russell Lewis McLaughlin, Marc Gotkine, Vivian Drory, Nicola Ticozzi, Vincenzo Silani, Mamede de Carvalho, Jesus S Mora, Monica Povedano, Peter Munch Andersen, Markus Weber, Ayse Nazli Basak, Xiao Chen, Michael A Eberle, Ammar Al Chalabi, Chris Shaw, Dame Pamela J Shaw, Karen E Morrison, John E Landers, Jonathan D Glass, Wim Robberecht, Michael A Van Es, Leonard H Van Den Berg, Jan Herman Veldink, Philip Van Damme, null null
The Effect of SMN Gene Dosage on ALS Risk and Disease Severity. Annals of neurology 89 (4) (2021)
Luisa Benussi, Antonio Longobardi, Cemile Kocoglu, Matteo Carrara, Sonia Bellini, Clarissa Ferrari, Roland Nicsanu, Claudia Saraceno, Cristian Bonvicini, Silvia Fostinelli, Roberta Zanardini, Marcella Catania, Matthieu Moisse, Philip Van Damme, Giuseppe Di Fede, Giuliano Binetti, Christine Van Broeckhoven, Julie van der Zee, Roberta Ghidoni
Investigating the Endo-Lysosomal System in Major Neurocognitive Disorders Due to Alzheimer's Disease, Frontotemporal Lobar Degeneration and Lewy Body Disease: Evidence for SORL1 as a Cross-Disease Gene. International journal of molecular sciences 22 (24) (2021)
Sien Hilde Van Daele, Matthieu Moisse, Valérie Race, Amélie Van Eesbeeck, Liesbeth Keldermans, Sascha Vermeer, Hilde Van Esch, Kristl G Claeys, Philip Van Damme
RNF170 mutation causes autosomal dominant sensory ataxia with variable pyramidal involvement. European journal of neurology 29 (1) (2021)
Ruben P A van Eijk, Stavros Nikolakopoulos, Kit C B Roes, Lindsay Kendall, Steve S Han, Arseniy Lavrov, Noam Epstein, Tessa Kliest, Adriaan D de Jongh, Henk-Jan Westeneng, Ammar Al Chalabi, Philip Van Damme, Orla Hardiman, Pamela J Shaw, Christopher J McDermott, Marinus J C Eijkemans, Leonard H van den Berg
Innovating Clinical Trials for Amyotrophic Lateral Sclerosis: Challenging the Established Order. Neurology 97 (11) (2021)
Wouter Van Rheenen, Rick A A van der Spek, Mark K Bakker, Joke J F A van Vugt, Paul J Hop, Ramona A J Zwamborn, Niek de Klein, Harm-Jan Westra, Olivier B Bakker, Patrick Deelen, Gemma Shireby, Eilis J Hannon, Matthieu Moisse, Denis Baird, Restuadi Restuadi, Egor Dolzhenko, Annelot M Dekker, Klara Gawor, Henk-Jan Westeneng, Gijs H P Tazelaar, Kristel R van Eijk, Maarten Kooyman, Ross P Byrne, Mark Doherty, Mark Heverin, Ahmad Al Khleifat, Alfredo Iacoangeli, Aleksey Shatunov, Nicola Ticozzi, Johnathan Cooper-Knock, Bradley N Smith, Marta Gromicho, Siddharthan Chandran, Suvankar Pal, Karen E Morrison, Pamela J Shaw, John Hardy, Richard W Orrell, Michael Sendtner, Thomas Meyer, Nazli Başak, Anneke J van der Kooi, Antonia Ratti, Isabella Fogh, Cinzia Gellera, Giuseppe Lauria, Stefania Corti, Cristina Cereda, Daisy Sproviero, Sandra D'Alfonso, Gianni Sorarù, Gabriele Siciliano, Massimiliano Filosto, Alessandro Padovani, Adriano Chiò, Andrea Calvo, Cristina Moglia, Maura Brunetti, Antonio Canosa, Maurizio Grassano, Ettore Beghi, Elisabetta Pupillo, Giancarlo Logroscino, Beatrice Nefussy, Alma Osmanovic, Angelica Nordin, Yossef Lerner, Michal Zabari, Marc Gotkine, Robert H Baloh, Shaughn Bell, Patrick Vourc'h, Philippe Corcia, Philippe Couratier, Stéphanie Millecamps, Vincent Meininger, François Salachas, Jesus S Mora Pardina, Abdelilah Assialioui, Ricardo Rojas-García, Patrick A Dion, Jay P Ross, Albert C Ludolph, Jochen H Weishaupt, David Brenner, Axel Freischmidt, Gilbert Bensimon, Alexis Brice, Alexandra Durr, Christine A M Payan, Safa Saker-Delye, Nicholas W Wood, Simon D Topp, Rosa Rademakers, Lukas Tittmann, Wolfgang Lieb, Andre Franke, Stephan Ripke, Alice Braun, Julia Kraft, David C Whiteman, Catherine M Olsen, Andre G Uitterlinden, Albert Hofman, Marcella D C Rietschel, Sven Cichon, Markus Maria Nöthen, Phillippe Amouyel, null null, null null, null null, null null, Bryan J Traynor, Andrew B Singleton, Miguel Mitne Neto, Ruben J Cauchi, Roel A Ophoff, Martina Wiedau-Pazos, Catherine Lomen-Hoerth, Vivanna M Van Deerlin, Julian Grosskreutz, Annekathrin Roediger, Nayana Gaur, Alexander Jörk, Tabea Barthel, Erik Theele, Benjamin Ilse, Beatrice Stubendorff, Otto W Witte, Robert Steinbach, Christian A Hübner, Caroline Graff, Lev Brylev, Vera Fominykh, Vera Demeshonok, Anastasia Ataulina, Boris Rogelj, Blaz Koritnik, Janez Zidar, Metka Ravnik-Glavač, Damjan Glavač, Zorica Stević, Vivian Drory, Monica Povedano, Ian P Blair, Matthew C Kiernan, Beben Benyamin, Robert D Henderson, Sarah Furlong, Susan Mathers, Pamela A McCombe, Merrilee Needham, Shyuan T Ngo, Garth A Nicholson, Roger Pamphlett, Dominic B Rowe, Frederik J Steyn, Kelly Louise Williams, Karen A Mather, Perminder Singh Sachdev, Anjali K Henders, Leanne Wallace, Mamede de Carvalho, Susana Pinto, Susanne Petri, Markus Weber, Guy A Rouleau, Vincenzo Silani, Charles J Curtis, Gerome D Breen, Jonathan D Glass, Robert H Brown, John E Landers, Christopher E Shaw, Peter Munch Andersen, Ewout Joan Nicolaas Groen, Michael A Van Es, Ronald Jeroen Pasterkamp, Dongsheng Fan, Fleur C Garton, Allan F McRae, George Davey Smith, Tom R Gaunt, Michael A Eberle, Jonathan S Mill, Russell Lewis McLaughlin, Orla Hardiman, Kevin P Kenna, Naomi R Wray, Ellen A Tsai, Heiko Runz, Lude H Franke, Ammar Al Chalabi, Philip Van Damme, Leonard H van den Berg, Jan Herman Veldink
Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology. Nature genetics 53 (12) (2021)
Deirdre Murray, James P K Rooney, Ammar Al Chalabi, Tommy Bunte, Theresa Chiwera, Mutahhara Choudhury, Adriano Chio, Lauren Fenton, Jennifer Fortune, Lindsay Maidment, Umberto Manera, Christopher J McDermott, Dara Meldrum, Myrte Meyjes, Rachel Tattersall, Maria Claudia Torrieri, Philip Van Damme, Elien Vanderlinden, Claire Wood, Leonard H Van Den Berg, Orla Hardiman
Correlations between measures of ALS respiratory function: is there an alternative to FVC? Amyotrophic lateral sclerosis & frontotemporal degeneration 22 (7-8) (2021)
Anna Månberg, Nathan Skene, Folkert Sanders, Marta Trusohamn, Julia Remnestål, Anna Szczepińska, Inci Sevval Aksoylu, Peter Lönnerberg, Lwaki Ebarasi, Stefan Wouters, Manuela Lehmann, Jennie Olofsson, Inti von Gohren Antequera, Aylin Domaniku, Maxim De Schaepdryver, Joke De Vocht, Koen Poesen, Mathias Uhlen, Jasper Anink, Caroline Mijnsbergen, Hermieneke Vergunst-Bosch, Annemarie Hübers, Ulf Kläppe, Elena Rodriguez-Vieitez, Jonathan D Gilthorpe, Eva Hedlund, Robert A Harris, Eleonora Aronica, Philip Van Damme, Albert Ludolph, Jan Herman Veldink, Caroline Ingre, Peter Nilsson, Sebastian A Lewandowski
Altered perivascular fibroblast activity precedes ALS disease onset. Nature medicine 27 (4) (2021)
Laura Fumagalli, Florence L Young, Steven Boeynaems, Mathias De Decker, Arpan R Mehta, Ann Swijsen, Raheem Fazal, Wenting Guo, Matthieu Moisse, Jimmy Beckers, Lieselot Dedeene, Bhuvaneish T Selvaraj, Tijs Vandoorne, Vanesa Madan, Marka van Blitterswijk, Denitza Raitcheva, Alexander McCampbell, Koen Poesen, Aaron D Gitler, Philipp Koch, Pieter Vanden Berghe, Dietmar Rudolf Thal, Catherine M Verfaillie, Siddharthan Chandran, Ludo Van Den Bosch, Simon L Bullock, Philip Van Damme
C9orf72-derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility. Science advances 7 (15) (2021)
Joke De Vocht, Daphne Stam, Marie Nicolini, Nikita Lamaire, Maarten Laroy, Thomas Vande Casteele, Laura Van De Vliet, Kristof Vansteelandt, Ann D'Hondt, Louise Emsell, Ronny Bruffaerts, Mathieu Vandenbulcke, Philip Van Damme, Jan Van den Stock
Psychopathology in premanifest C9orf72 repeat expansion carriers. Journal of neurology, neurosurgery, and psychiatry (2021)
Petra Steinacker, Emily Feneberg, Steffen Halbgebauer, Simon Witzel, Federico Verde, Patrick Oeckl, Philip Van Damme, Nayana Gaur, Elizabeth Gray, Julian Grosskreutz, Claude G Jardel, Mykyta Kachanov, Jens Kuhle, Foudil Lamari, Aleksandra Maceski, Maria Del Mar Amador, Benjamin Mayer, Claudia Morelli, Susanne Petri, Koen Poesen, Joost Raaphorst, François Salachas, Vincenzo Silani, Matthew C Kiernan, Marcel M Verbeek, Alexander E Volk, Jochen H Weishaupt, Patrick Weydt, Albert C Ludolph, Markus Otto
Chitotriosidase as biomarker for early stage amyotrophic lateral sclerosis: a multicenter study. Amyotrophic lateral sclerosis & frontotemporal degeneration 22 (3-4) (2021)
Thibaut Burg, Elisabeth Rossaert, Matthieu Moisse, Philip Van Damme, Ludo Van Den Bosch
Histone Deacetylase Inhibition Regulates Lipid Homeostasis in a Mouse Model of Amyotrophic Lateral Sclerosis. International journal of molecular sciences 22 (20) (2021)
Jimmy Beckers, Arun Kumar Tharkeshwar, Philip Van Damme
C9orf72 ALS-FTD: recent evidence for dysregulation of the autophagy-lysosome pathway at multiple levels. Autophagy 17 (11) (2021)
Pegah Masrori, Maxim De Schaepdryver, Mary Kay Floeter, Joke De Vocht, Nikita Lamaire, Ann D'Hondt, Bryan Traynor, Koen Poesen, Philip Van Damme
Prognostic relationship of neurofilaments, CHIT1, YKL-40 and MCP-1 in amyotrophic lateral sclerosis. Journal of neurology, neurosurgery, and psychiatry 93 (6) (2021)
Joris Godelaine, Maxim De Schaepdryver, Xavier Bossuyt, Philip Van Damme, Kristl G Claeys, Koen Poesen
Prognostic value of neurofilament light chain in chronic inflammatory demyelinating polyneuropathy. Brain communications 3 (1) (2021)
Raheem Fazal, Steven Boeynaems, Ann Swijsen, Mathias De Decker, Laura Fumagalli, Matthieu Moisse, Joni Vanneste, Wenting Guo, Ruben Boon, Thomas Vercruysse, Kristel Eggermont, Bart Swinnen, Jimmy Beckers, Donya Pakravan, Tijs Vandoorne, Pieter Vanden Berghe, Catherine Verfaillie, Ludo Van Den Bosch, Philip Van Damme
HDAC6 inhibition restores TDP-43 pathology and axonal transport defects in human motor neurons with TARDBP mutations. The EMBO journal 40 (7) (2021)
Maxim De Schaepdryver, Christian Lunetta, Claudia Tarlarini, Lorena Mosca, Adriano Chio, Philip Van Damme, Koen Poesen
Neurofilament light chain and C reactive protein explored as predictors of survival in amyotrophic lateral sclerosis. Journal of neurology, neurosurgery, and psychiatry 91 (4) (2020)
Pegah Masrori, Philip Van Damme
Amyotrophic lateral sclerosis: a clinical review. European journal of neurology 27 (10) (2020)
Eva Maria Johanna de Boer, Viyanti K Orie, Timothy Williams, Mark R Baker, Hugo M De Oliveira, Tuomo Polvikoski, Matthew Silsby, Parvathi Menon, Mehdi A J van den Bos, Glenda M Halliday, Leonard H van den Berg, Ludo Van Den Bosch, Philip Van Damme, Matthew C Kiernan, Michael A van Es, Steve Vucic
TDP-43 proteinopathies: a new wave of neurodegenerative diseases. Journal of neurology, neurosurgery, and psychiatry (2020)
Ruben P A van Eijk, Tessa Kliest, Christopher J McDermott, Kit C B Roes, Philip Van Damme, Adriano Chio, Markus Weber, Caroline Ingre, Philippe Corcia, Mònica Povedano, Evy Reviers, Michael A van Es, Ammar Al Chalabi, Orla Hardiman, Leonard H van den Berg
TRICALS: creating a highway toward a cure. Amyotrophic lateral sclerosis & frontotemporal degeneration 21 (7-8) (2020)
Sien Hilde Van Daele, Sascha Vermeer, Amélie Van Eesbeeck, Laura Lannoo, Valérie Race, Philip Van Damme, Kristl Claeys, Wim Vandenberghe
Diagnostic yield of testing for RFC1 repeat expansions in patients with unexplained adult-onset cerebellar ataxia. Journal of neurology, neurosurgery, and psychiatry 91 (11) (2020)
Philip Van Damme, Petra Tilkin, Katarina Jansson Mercer, Joke Terryn, Ann D'Hondt, Nina Herne, Thomas Tousseyn, Kristl G Claeys, Dietmar Rudolf Thal, Olof Zachrisson, Per Almqvist, Bart Nuttin, Markus Jerling, Folke Bernadotte, Anders Haegerstrand, Wim Robberecht
Intracerebroventricular delivery of vascular endothelial growth factor in patients with amyotrophic lateral sclerosis, a phase I study. Brain communications 2 (2) (2020)
Gijs H P Tazelaar, Steven Boeynaems, Mathias De Decker, Joke J F A van Vugt, Lindy Kool, H Stephan Goedee, Russell L McLaughlin, William Sproviero, Alfredo Iacoangeli, Matthieu Moisse, Maarten Jacquemyn, Dirk Daelemans, Annelot M Dekker, Rick A van der Spek, Henk-Jan Westeneng, Kevin P Kenna, Abdelilah Assialioui, Nica Da Silva, null null, Mónica Povedano, Jesus S Mora Pardina, Orla Hardiman, François Salachas, Stéphanie Millecamps, Patrick Vourc'h, Philippe Corcia, Philippe Couratier, Karen E Morrison, Pamela J Shaw, Christopher E Shaw, R Jeroen Pasterkamp, John E Landers, Ludo Van Den Bosch, Wim Robberecht, Ammar Al-Chalabi, Leonard H van den Berg, Philip Van Damme, Jan H Veldink, Michael A Van Es
ATXN1 repeat expansions confer risk for amyotrophic lateral sclerosis and contribute to TDP-43 mislocalization. Brain communications 2 (2) (2020)
Maarten Van Hemelen, Kristl Claeys, Philip Van Damme, Bart Hendriks, Petra Dewulf, Peter Rogiers, Alexander Wilmer
Papillary thyroid carcinoma presenting with severe Guillain-Barré syndrome. Acta clinica Belgica 76 (3) (2019)
Benjamin Gille, Maxim De Schaepdryver, Lieselot Dedeene, Janne Goossens, Kristl G Claeys, Ludo Van Den Bosch, Jos Tournoy, Philip Van Damme, Koen Poesen
Inflammatory markers in cerebrospinal fluid: independent prognostic biomarkers in amyotrophic lateral sclerosis? Journal of neurology, neurosurgery, and psychiatry 90 (12) (2019)
Lieselot Dedeene, Evelien Van Schoor, Valérie Race, Matthieu Moisse, Rik Vandenberghe, Koen Poesen, Philip Van Damme, Dietmar Rudolf Thal
An ALS case with 38 (G4C2)-repeats in the C9orf72 gene shows TDP-43 and sparse dipeptide repeat protein pathology. Acta neuropathologica 137 (5) (2019)
Joni Vanneste, Thomas Vercruysse, Steven Boeynaems, Adria Sicart, Philip Van Damme, Dirk Daelemans, Ludo Van Den Bosch
C9orf72-generated poly-GR and poly-PR do not directly interfere with nucleocytoplasmic transport. Scientific reports 9 (1) (2019)
Leonhard A Bakker, Carin D SchrÖder, Lauriane A Spreij, Marianne Verhaegen, Joke De Vocht, Philip Van Damme, Jan H Veldink, Johanna M A Visser-Meily, Leonard H Van Den Berg, Tanja C W Nijboer, Michael A Van Es
Derivation of norms for the Dutch version of the Edinburgh cognitive and behavioral ALS screen. Amyotrophic lateral sclerosis & frontotemporal degeneration 20 (1-2) (2018)
Sander Beel, Sarah Herdewyn, Raheem Fazal, Mathias De Decker, Matthieu Moisse, Wim Robberecht, Ludo Van Den Bosch, Philip Van Damme
Progranulin reduces insoluble TDP-43 levels, slows down axonal degeneration and prolongs survival in mutant TDP-43 mice. Molecular neurodegeneration 13 (1) (2018)
Philip Van Damme
How much of the missing heritability of ALS is hidden in known ALS genes? Journal of neurology, neurosurgery, and psychiatry 89 (8) (2018)
Philip Van Damme, Wim Robberecht, Ludo Van Den Bosch
Modelling amyotrophic lateral sclerosis: progress and possibilities. Disease models & mechanisms 10 (5) (2018)
Philip Van Damme
Another piece in the progranulin puzzle: special binding between progranulin and prosaposin creates additional lysosomal access: An Editorial Comment for 'The interaction between progranulin and prosaposin is mediated by granulins and the linker region between saposin B and C' on page 236. Journal of neurochemistry 143 (2) (2017)
Wenting Guo, Maximilian Naujock, Laura Fumagalli, Tijs Vandoorne, Pieter Baatsen, Ruben Boon, Laura Ordovás, Abdulsamie Patel, Marc Welters, Thomas Vanwelden, Natasja Geens, Tine Tricot, Veronick Benoy, Jolien Steyaert, Cynthia Lefebvre-Omar, Werend Boesmans, Matthew Jarpe, Jared Sterneckert, Florian Wegner, Susanne Petri, Delphine Bohl, Pieter Vanden Berghe, Wim Robberecht, Philip Van Damme, Catherine M Verfaillie, Ludo Van Den Bosch
HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients. Nature communications 8 (1) (2017)

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Philip Van Damme (Philip van Damme, P Van Damme)