Sarah-Maria Fendt

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 54

Top Topics

Histone Deacetylase

Top Venues

Nature communications

Nature immunology

Nature metabolism

This page only lists publications with an associated author ORCID identifier.

Publications

Tommaso Scolaro, Marta Manco, Mathieu Pecqueux, Ricardo Amorim, Rosa Trotta, Heleen H Van Acker, Matthias Van Haele, Niranjan Shirgaonkar, Stefan Naulaerts, Jan Daniluk, Fran Prenen, Chiara Varamo, Donatella Ponti, Ginevra Doglioni, Ana Margarida Ferreira Campos, Juan Fernández-García, Silvia Radenkovic, Pegah Rouhi, Aleksandar Beatovic, Liwei Wang, Yu Wang, Amalia Tzoumpa, Asier Antoranz, Ara Sargsian, Mario Di Matteo, Emanuele Berardi, Jermaine Goveia, Bart Ghesquiere, Tania Roskams, Stefaan J Soenen, Thomas Voets, Bella Manshian, Sarah-Maria Fendt, Peter Carmeliet, Abhishek Dinkarnath Garg, Ramanuj DasGupta, Baki Topal, Massimilliano Mazzone
Nucleotide metabolism in cancer cells fuels a UDP-driven macrophage cross-talk, promoting immunosuppression and immunotherapy resistance. Nature cancer 5 (8) (2024)
Tatjana Geukens, Maxim De Schepper, Wouter Van Den Bogaert, Karen Van Baelen, Marion Maetens, Anirudh Pabba, Amena Mahdami, Sophia Leduc, Edoardo Isnaldi, Ha-Linh Nguyen, Imane Bachir, Maysam Hajipirloo, Gitte Zels, Josephine Van Cauwenberge, Kristien Borremans, Vincent Vandecaveye, Birgit Weynand, Peter Vermeulen, Eleonora Leucci, Maria Francesca Baietti, George Sflomos, Laura Battista, Cathrin Brisken, Patrick W B Derksen, Thijs Koorman, Daan Visser, Colinda L G J Scheele, Daniela S Thommen, Sigrid Hatse, Sarah-Maria Fendt, Evy Vanderheyden, Thomas Van Brussel, Rogier Schepers, Bram Boeckx, Diether Lambrechts, Giuseppe Marano, Elia Mario Biganzoli, Ann Smeets, Ines Nevelsteen, Kevin Punie, Patrick Neven, Hans P M W Wildiers, François Richard, Giuseppe Floris, Christine Desmedt
Rapid autopsies to enhance metastatic research: the UPTIDER post-mortem tissue donation program. NPJ breast cancer 10 (1) (2024)
Tatjana Geukens, Maxim De Schepper, Wouter Van Den Bogaert, Karen Van Baelen, Marion Maetens, Anirudh Pabba, Amena Mahdami, Sophia Leduc, Edoardo Isnaldi, Ha-Linh Nguyen, Imane Bachir, Maysam Hajipirloo, Gitte Zels, Josephine Van Cauwenberge, Kristien Borremans, Vincent Vandecaveye, Birgit Weynand, Peter Vermeulen, Eleonora Leucci, Maria Francesca Baietti, George Sflomos, Laura Battista, Cathrin Brisken, Patrick W B Derksen, Thijs Koorman, Daan Visser, Colinda L G J Scheele, Daniela S Thommen, Sigrid Hatse, Sarah-Maria Fendt, Evy Vanderheyden, Thomas Van Brussel, Rogier Schepers, Bram Boeckx, Diether Lambrechts, Giuseppe Marano, Elia Mario Biganzoli, Ann Smeets, Ines Nevelsteen, Kevin Punie, Patrick Neven, Hans P M W Wildiers, François Richard, Giuseppe Floris, Christine Desmedt
Rapid autopsies to enhance metastatic research: the UPTIDER post-mortem tissue donation program. NPJ breast cancer 10 (1) (2024)
Sarah Krieg, Sara Isabelle Fernandes, Constantinos Kolliopoulos, Ming Liu, Sarah-Maria Fendt
Metabolic Signaling in Cancer Metastasis. Cancer discovery 14 (6) (2024)
Margherita Demicco, Xiao-Zheng Liu, Katharina Leithner, Sarah-Maria Fendt
Metabolic heterogeneity in cancer. Nature metabolism (2024)
Tommaso Scolaro, Marta Manco, Mathieu Pecqueux, Ricardo Amorim, Rosa Trotta, Heleen H Van Acker, Matthias Van Haele, Niranjan Shirgaonkar, Stefan Naulaerts, Jan Daniluk, Fran Prenen, Chiara Varamo, Donatella Ponti, Ginevra Doglioni, Ana Margarida Ferreira Campos, Juan Fernández-García, Silvia Radenkovic, Pegah Rouhi, Aleksandar Beatovic, Liwei Wang, Yu Wang, Amalia Tzoumpa, Asier Antoranz, Ara Sargsian, Mario Di Matteo, Emanuele Berardi, Jermaine Goveia, Bart Ghesquiere, Tania Roskams, Stefaan J Soenen, Thomas Voets, Bella Manshian, Sarah-Maria Fendt, Peter Carmeliet, Abhishek Dinkarnath Garg, Ramanuj DasGupta, Baki Topal, Massimilliano Mazzone
Nucleotide metabolism in cancer cells fuels a UDP-driven macrophage cross-talk, promoting immunosuppression and immunotherapy resistance. Nature cancer 5 (8) (2024)
Tal Levy, Kai Voeltzke, Laura Hruby, Khawla Alasad, Zuelal Bas, Marteinn T Snaebjornsson, Ran Marciano, Katerina Scharov, Mélanie Planque, Kim Vriens, Stefan Christen, Cornelius Maximilian Funk, Christina Hassiepen, Alisa Kahler, Beate Heider, Daniel Picard, Jonathan K M Lim, Anja Stefanski, Katja Bendrin, Andres Vargas-Toscano, Ulf Dietrich Kahlert, Kai Stühler, Marc Remke, Moshe Elkabets, Thomas G P Grünewald, Andreas S Reichert, Sarah-Maria Fendt, Almut Schulze, Guido Reifenberger, Barak Rotblat, Gabriel Leprivier
mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism. Nature communications 15 (1) (2024)
Margherita Demicco, Xiao-Zheng Liu, Katharina Leithner, Sarah-Maria Fendt
Metabolic heterogeneity in cancer. Nature metabolism 6 (1) (2024)
Sarah Krieg, Sara Isabelle Fernandes, Constantinos Kolliopoulos, Ming Liu, Sarah-Maria Fendt
Metabolic Signaling in Cancer Metastasis. Cancer discovery 14 (6) (2024)
Sarah Krieg, Sara Isabelle Fernandes, Constantinos Kolliopoulos, Ming Liu, Sarah-Maria Fendt
Metabolic Signaling in Cancer Metastasis. Cancer discovery (2024)
Margherita Demicco, Xiao-Zheng Liu, Katharina Leithner, Sarah-Maria Fendt
Metabolic heterogeneity in cancer. Nature metabolism 6 (1) (2024)
Tatjana Geukens, Maxim De Schepper, Wouter Van Den Bogaert, Karen Van Baelen, Marion Maetens, Anirudh Pabba, Amena Mahdami, Sophia Leduc, Edoardo Isnaldi, Ha-Linh Nguyen, Imane Bachir, Maysam Hajipirloo, Gitte Zels, Josephine Van Cauwenberge, Kristien Borremans, Vincent Vandecaveye, Birgit Weynand, Peter Vermeulen, Eleonora Leucci, Maria Francesca Baietti, George Sflomos, Laura Battista, Cathrin Brisken, Patrick W B Derksen, Thijs Koorman, Daan Visser, Colinda L G J Scheele, Daniela S Thommen, Sigrid Hatse, Sarah-Maria Fendt, Evy Vanderheyden, Thomas Van Brussel, Rogier Schepers, Bram Boeckx, Diether Lambrechts, Giuseppe Marano, Elia Mario Biganzoli, Ann Smeets, Ines Nevelsteen, Kevin Punie, Patrick Neven, Hans P M W Wildiers, François Richard, Giuseppe Floris, Christine Desmedt
Rapid autopsies to enhance metastatic research: the UPTIDER post-mortem tissue donation program. NPJ breast cancer 10 (1) (2024)
Margherita Demicco, Xiao-Zheng Liu, Katharina Leithner, Sarah-Maria Fendt
Metabolic heterogeneity in cancer. Nature metabolism 6 (1) (2024)
Sarah Krieg, Sara Isabelle Fernandes, Constantinos Kolliopoulos, Ming Liu, Sarah-Maria Fendt
Metabolic Signaling in Cancer Metastasis. Cancer discovery 14 (6) (2024)
Tal Levy, Kai Voeltzke, Laura Hruby, Khawla Alasad, Zuelal Bas, Marteinn T Snaebjornsson, Ran Marciano, Katerina Scharov, Mélanie Planque, Kim Vriens, Stefan Christen, Cornelius Maximilian Funk, Christina Hassiepen, Alisa Kahler, Beate Heider, Daniel Picard, Jonathan K M Lim, Anja Stefanski, Katja Bendrin, Andres Vargas-Toscano, Ulf Dietrich Kahlert, Kai Stühler, Marc Remke, Moshe Elkabets, Thomas G P Grünewald, Andreas S Reichert, Sarah-Maria Fendt, Almut Schulze, Guido Reifenberger, Barak Rotblat, Gabriel Leprivier
mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism. Nature communications 15 (1) (2024)
Tommaso Scolaro, Marta Manco, Mathieu Pecqueux, Ricardo Amorim, Rosa Trotta, Heleen H Van Acker, Matthias Van Haele, Niranjan Shirgaonkar, Stefan Naulaerts, Jan Daniluk, Fran Prenen, Chiara Varamo, Donatella Ponti, Ginevra Doglioni, Ana Margarida Ferreira Campos, Juan Fernández-García, Silvia Radenkovic, Pegah Rouhi, Aleksandar Beatovic, Liwei Wang, Yu Wang, Amalia Tzoumpa, Asier Antoranz, Ara Sargsian, Mario Di Matteo, Emanuele Berardi, Jermaine Goveia, Bart Ghesquiere, Tania Roskams, Stefaan J Soenen, Thomas Voets, Bella Manshian, Sarah-Maria Fendt, Peter Carmeliet, Abhishek Dinkarnath Garg, Ramanuj DasGupta, Baki Topal, Massimilliano Mazzone
Nucleotide metabolism in cancer cells fuels a UDP-driven macrophage cross-talk, promoting immunosuppression and immunotherapy resistance. Nature cancer (2024)
Tommaso Scolaro, Marta Manco, Mathieu Pecqueux, Ricardo Amorim, Rosa Trotta, Heleen H Van Acker, Matthias Van Haele, Niranjan Shirgaonkar, Stefan Naulaerts, Jan Daniluk, Fran Prenen, Chiara Varamo, Donatella Ponti, Ginevra Doglioni, Ana Margarida Ferreira Campos, Juan Fernández-García, Silvia Radenkovic, Pegah Rouhi, Aleksandar Beatovic, Liwei Wang, Yu Wang, Amalia Tzoumpa, Asier Antoranz, Ara Sargsian, Mario Di Matteo, Emanuele Berardi, Jermaine Goveia, Bart Ghesquiere, Tania Roskams, Stefaan J Soenen, Thomas Voets, Bella Manshian, Sarah-Maria Fendt, Peter Carmeliet, Abhishek Dinkarnath Garg, Ramanuj DasGupta, Baki Topal, Massimilliano Mazzone
Nucleotide metabolism in cancer cells fuels a UDP-driven macrophage cross-talk, promoting immunosuppression and immunotherapy resistance. Nature cancer 5 (8) (2024)
Tal Levy, Kai Voeltzke, Laura Hruby, Khawla Alasad, Zuelal Bas, Marteinn T Snaebjornsson, Ran Marciano, Katerina Scharov, Mélanie Planque, Kim Vriens, Stefan Christen, Cornelius Maximilian Funk, Christina Hassiepen, Alisa Kahler, Beate Heider, Daniel Picard, Jonathan K M Lim, Anja Stefanski, Katja Bendrin, Andres Vargas-Toscano, Ulf Dietrich Kahlert, Kai Stühler, Marc Remke, Moshe Elkabets, Thomas G P Grünewald, Andreas S Reichert, Sarah-Maria Fendt, Almut Schulze, Guido Reifenberger, Barak Rotblat, Gabriel Leprivier
mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism. Nature communications 15 (1) (2024)
Tommaso Scolaro, Marta Manco, Mathieu Pecqueux, Ricardo Amorim, Rosa Trotta, Heleen H Van Acker, Matthias Van Haele, Niranjan Shirgaonkar, Stefan Naulaerts, Jan Daniluk, Fran Prenen, Chiara Varamo, Donatella Ponti, Ginevra Doglioni, Ana Margarida Ferreira Campos, Juan Fernández-García, Silvia Radenkovic, Pegah Rouhi, Aleksandar Beatovic, Liwei Wang, Yu Wang, Amalia Tzoumpa, Asier Antoranz, Ara Sargsian, Mario Di Matteo, Emanuele Berardi, Jermaine Goveia, Bart Ghesquiere, Tania Roskams, Stefaan J Soenen, Thomas Voets, Bella Manshian, Sarah-Maria Fendt, Peter Carmeliet, Abhishek Dinkarnath Garg, Ramanuj DasGupta, Baki Topal, Massimilliano Mazzone
Nucleotide metabolism in cancer cells fuels a UDP-driven macrophage cross-talk, promoting immunosuppression and immunotherapy resistance. Nature cancer (2024)
Pu-Ste Liu, Yi-Ting Chen, Xiaoyun Li, Pei-Chun Hsueh, Sheue-Fen Tzeng, Hsi Chen, Pei-Zhu Shi, Xin Xie, Sweta Parik, Mélanie Planque, Sarah-Maria Fendt, Ping-Chih Ho
CD40 signal rewires fatty acid and glutamine metabolism for stimulating macrophage anti-tumorigenic functions. Nature immunology 24 (3) (2023)
Pu-Ste Liu, Yi-Ting Chen, Xiaoyun Li, Pei-Chun Hsueh, Sheue-Fen Tzeng, Hsi Chen, Pei-Zhu Shi, Xin Xie, Sweta Parik, Mélanie Planque, Sarah-Maria Fendt, Ping-Chih Ho
CD40 signal rewires fatty acid and glutamine metabolism for stimulating macrophage anti-tumorigenic functions. Nature immunology 24 (3) (2023)
Mitsugu Shimobayashi, Amandine Thomas, Sunil Shetty, Irina C Frei, Bettina K Wölnerhanssen, Diana Weissenberger, Anke Vandekeere, Mélanie Planque, Nikolaus Dietz, Danilo Ritz, Anne Christin Meyer-Gerspach, Timm Maier, Nissim Hay, Ralph Peterli, Sarah-Maria Fendt, Nicolas Rohner, Michael N Hall
Diet-induced loss of adipose hexokinase 2 correlates with hyperglycemia. eLife 12 (2023)
Mitsugu Shimobayashi, Amandine Thomas, Sunil Shetty, Irina C Frei, Bettina K Wölnerhanssen, Diana Weissenberger, Anke Vandekeere, Mélanie Planque, Nikolaus Dietz, Danilo Ritz, Anne Christin Meyer-Gerspach, Timm Maier, Nissim Hay, Ralph Peterli, Sarah-Maria Fendt, Nicolas Rohner, Michael N Hall
Diet-induced loss of adipose hexokinase 2 correlates with hyperglycemia. eLife 12 (2023)
Pu-Ste Liu, Yi-Ting Chen, Xiaoyun Li, Pei-Chun Hsueh, Sheue-Fen Tzeng, Hsi Chen, Pei-Zhu Shi, Xin Xie, Sweta Parik, Mélanie Planque, Sarah-Maria Fendt, Ping-Chih Ho
Author Correction: CD40 signal rewires fatty acid and glutamine metabolism for stimulating macrophage anti-tumorigenic functions. Nature immunology (2023)
Patricia Altea-Manzano, Ginevra Doglioni, Yawen Liu, Alejandro M Cuadros, Emma Nolan, Juan Fernández-García, Qi Wu, Mélanie Planque, Kathrin Julia Laue, Florencia Cidre-Aranaz, Xiao-Zheng Liu, Oskar Marin-Bejar, Joke Van Elsen, Ines Vermeire, Dorien Broekaert, Sofie Demeyer, Xander Spotbeen, Jakub Idkowiak, Aurélie Montagne, Margherita Demicco, H Furkan Alkan, Nick Rabas, Carla Riera-Domingo, François Richard, Tatjana Geukens, Maxim De Schepper, Sophia Leduc, Sigrid Hatse, Yentl Lambrechts, Emily Jane Kay, Sergio Lilla, Alisa Alekseenko, Vincent Geldhof, Bram Boeckx, Celia de la Calle Arregui, Giuseppe Floris, Johannes V Swinnen, Jean-Christophe Marine, Diether Lambrechts, Vicent Pelechano, Massimilliano Mazzone, Sara R Zanivan, Jan Cools, Hans P M W Wildiers, Veronique Baud, Thomas G P Grünewald, Uri Ben-David, Christine Desmedt, Ilaria Malanchi, Sarah-Maria Fendt
A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling. Nature cancer (2023)
Ryohei Iwata, Pierre Casimir, Emir Erkol, Leïla Boubakar, Mélanie Planque, Isabel M Gallego López, Martyna Ditkowska, Vaiva Gaspariunaite, Sofie Beckers, Daan Remans, Katlijn Vints, Anke Vandekeere, Suresh Poovathingal, Matthew Bird, Ine Vlaeminck, Eline Creemers, Keimpe Wierda, Nikky Corthout, Pieter Vermeersch, Sebastien Christian Carpentier, Kristofer Davie, Massimilliano Mazzone, Natalia V Gounko, Stein Aerts, Bart Ghesquiere, Sarah-Maria Fendt, Pierre Vanderhaeghen
Mitochondria metabolism sets the species-specific tempo of neuronal development. Science (New York, N.Y.) 379 (6632) (2023)
Pu-Ste Liu, Yi-Ting Chen, Xiaoyun Li, Pei-Chun Hsueh, Sheue-Fen Tzeng, Hsi Chen, Pei-Zhu Shi, Xin Xie, Sweta Parik, Mélanie Planque, Sarah-Maria Fendt, Ping-Chih Ho
CD40 signal rewires fatty acid and glutamine metabolism for stimulating macrophage anti-tumorigenic functions. Nature immunology 24 (3) (2023)
Ryohei Iwata, Pierre Casimir, Emir Erkol, Leïla Boubakar, Mélanie Planque, Isabel M Gallego López, Martyna Ditkowska, Vaiva Gaspariunaite, Sofie Beckers, Daan Remans, Katlijn Vints, Anke Vandekeere, Suresh Poovathingal, Matthew Bird, Ine Vlaeminck, Eline Creemers, Keimpe Wierda, Nikky Corthout, Pieter Vermeersch, Sebastien Christian Carpentier, Kristofer Davie, Massimilliano Mazzone, Natalia V Gounko, Stein Aerts, Bart Ghesquiere, Sarah-Maria Fendt, Pierre Vanderhaeghen
Mitochondria metabolism sets the species-specific tempo of neuronal development. Science (New York, N.Y.) 379 (6632) (2023)
Patricia Altea-Manzano, Ginevra Doglioni, Yawen Liu, Alejandro M Cuadros, Emma Nolan, Juan Fernández-García, Qi Wu, Mélanie Planque, Kathrin Julia Laue, Florencia Cidre-Aranaz, Xiao-Zheng Liu, Oskar Marin-Bejar, Joke Van Elsen, Ines Vermeire, Dorien Broekaert, Sofie Demeyer, Xander Spotbeen, Jakub Idkowiak, Aurélie Montagne, Margherita Demicco, H Furkan Alkan, Nick Rabas, Carla Riera-Domingo, François Richard, Tatjana Geukens, Maxim De Schepper, Sophia Leduc, Sigrid Hatse, Yentl Lambrechts, Emily Jane Kay, Sergio Lilla, Alisa Alekseenko, Vincent Geldhof, Bram Boeckx, Celia de la Calle Arregui, Giuseppe Floris, Johannes V Swinnen, Jean-Christophe Marine, Diether Lambrechts, Vicent Pelechano, Massimilliano Mazzone, Sara R Zanivan, Jan Cools, Hans P M W Wildiers, Veronique Baud, Thomas G P Grünewald, Uri Ben-David, Christine Desmedt, Ilaria Malanchi, Sarah-Maria Fendt
A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling. Nature cancer (2023)
Patricia Altea-Manzano, Ginevra Doglioni, Yawen Liu, Alejandro M Cuadros, Emma Nolan, Juan Fernández-García, Qi Wu, Mélanie Planque, Kathrin Julia Laue, Florencia Cidre-Aranaz, Xiao-Zheng Liu, Oskar Marin-Bejar, Joke Van Elsen, Ines Vermeire, Dorien Broekaert, Sofie Demeyer, Xander Spotbeen, Jakub Idkowiak, Aurélie Montagne, Margherita Demicco, H Furkan Alkan, Nick Rabas, Carla Riera-Domingo, François Richard, Tatjana Geukens, Maxim De Schepper, Sophia Leduc, Sigrid Hatse, Yentl Lambrechts, Emily Jane Kay, Sergio Lilla, Alisa Alekseenko, Vincent Geldhof, Bram Boeckx, Celia de la Calle Arregui, Giuseppe Floris, Johannes V Swinnen, Jean-Christophe Marine, Diether Lambrechts, Vicent Pelechano, Massimilliano Mazzone, Sara R Zanivan, Jan Cools, Hans P M W Wildiers, Veronique Baud, Thomas G P Grünewald, Uri Ben-David, Christine Desmedt, Ilaria Malanchi, Sarah-Maria Fendt
A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling. Nature cancer (2023)
Ryohei Iwata, Pierre Casimir, Emir Erkol, Leïla Boubakar, Mélanie Planque, Isabel M Gallego López, Martyna Ditkowska, Vaiva Gaspariunaite, Sofie Beckers, Daan Remans, Katlijn Vints, Anke Vandekeere, Suresh Poovathingal, Matthew Bird, Ine Vlaeminck, Eline Creemers, Keimpe Wierda, Nikky Corthout, Pieter Vermeersch, Sebastien Christian Carpentier, Kristofer Davie, Massimilliano Mazzone, Natalia V Gounko, Stein Aerts, Bart Ghesquiere, Sarah-Maria Fendt, Pierre Vanderhaeghen
Mitochondria metabolism sets the species-specific tempo of neuronal development. Science (New York, N.Y.) 379 (6632) (2023)
Ryohei Iwata, Pierre Casimir, Emir Erkol, Leïla Boubakar, Mélanie Planque, Isabel M Gallego López, Martyna Ditkowska, Vaiva Gaspariunaite, Sofie Beckers, Daan Remans, Katlijn Vints, Anke Vandekeere, Suresh Poovathingal, Matthew Bird, Nikky Corthout, Pieter Vermeersch, Sebastien Christian Carpentier, Kristofer Davie, Massimilliano Mazzone, Natalia V Gounko, Stein Aerts, Bart Ghesquiere, Sarah-Maria Fendt, Pierre Vanderhaeghen
Mitochondria metabolism sets the species-specific tempo of neuronal development. Science (New York, N.Y.) (2023)
Mitsugu Shimobayashi, Amandine Thomas, Sunil Shetty, Irina C Frei, Bettina K Wölnerhanssen, Diana Weissenberger, Anke Vandekeere, Mélanie Planque, Nikolaus Dietz, Danilo Ritz, Anne Christin Meyer-Gerspach, Timm Maier, Nissim Hay, Ralph Peterli, Sarah-Maria Fendt, Nicolas Rohner, Michael N Hall
Diet-induced loss of adipose hexokinase 2 correlates with hyperglycemia. eLife 12 (2023)
Steven E Pilley, Marc Hennequart, Anke Vandekeere, Julianna Blagih, Nathalie M Legrave, Sarah-Maria Fendt, Karen H Vousden, Christiaan F Labuschagne
Loss of attachment promotes proline accumulation and excretion in cancer cells. Science advances 9 (36) (2023)
Patricia Altea-Manzano, Ginevra Doglioni, Yawen Liu, Alejandro M Cuadros, Emma Nolan, Juan Fernández-García, Qi Wu, Mélanie Planque, Kathrin Julia Laue, Florencia Cidre-Aranaz, Xiao-Zheng Liu, Oskar Marin-Bejar, Joke Van Elsen, Ines Vermeire, Dorien Broekaert, Sofie Demeyer, Xander Spotbeen, Jakub Idkowiak, Aurélie Montagne, Margherita Demicco, H Furkan Alkan, Nick Rabas, Carla Riera-Domingo, François Richard, Tatjana Geukens, Maxim De Schepper, Sophia Leduc, Sigrid Hatse, Yentl Lambrechts, Emily Jane Kay, Sergio Lilla, Alisa Alekseenko, Vincent Geldhof, Bram Boeckx, Celia de la Calle Arregui, Giuseppe Floris, Johannes V Swinnen, Jean-Christophe Marine, Diether Lambrechts, Vicent Pelechano, Massimilliano Mazzone, Sara R Zanivan, Jan Cools, Hans P M W Wildiers, Veronique Baud, Thomas G P Grünewald, Uri Ben-David, Christine Desmedt, Ilaria Malanchi, Sarah-Maria Fendt
A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling. Nature cancer (2023)
Ryohei Iwata, Pierre Casimir, Emir Erkol, Leïla Boubakar, Mélanie Planque, Isabel M Gallego López, Martyna Ditkowska, Vaiva Gaspariunaite, Sofie Beckers, Daan Remans, Katlijn Vints, Anke Vandekeere, Suresh Poovathingal, Matthew Bird, Ine Vlaeminck, Eline Creemers, Keimpe Wierda, Nikky Corthout, Pieter Vermeersch, Sebastien Christian Carpentier, Kristofer Davie, Massimilliano Mazzone, Natalia V Gounko, Stein Aerts, Bart Ghesquiere, Sarah-Maria Fendt, Pierre Vanderhaeghen
Mitochondria metabolism sets the species-specific tempo of neuronal development. Science (New York, N.Y.) 379 (6632) (2023)
Mitsugu Shimobayashi, Amandine Thomas, Sunil Shetty, Irina C Frei, Bettina K Wölnerhanssen, Diana Weissenberger, Anke Vandekeere, Mélanie Planque, Nikolaus Dietz, Danilo Ritz, Anne Christin Meyer-Gerspach, Timm Maier, Nissim Hay, Ralph Peterli, Sarah-Maria Fendt, Nicolas Rohner, Michael N Hall
Diet-induced loss of adipose hexokinase 2 correlates with hyperglycemia. eLife 12 (2023)
Pu-Ste Liu, Yi-Ting Chen, Xiaoyun Li, Pei-Chun Hsueh, Sheue-Fen Tzeng, Hsi Chen, Pei-Zhu Shi, Xin Xie, Sweta Parik, Mélanie Planque, Sarah-Maria Fendt, Ping-Chih Ho
CD40 signal rewires fatty acid and glutamine metabolism for stimulating macrophage anti-tumorigenic functions. Nature immunology 24 (3) (2023)
Pu-Ste Liu, Yi-Ting Chen, Xiaoyun Li, Pei-Chun Hsueh, Sheue-Fen Tzeng, Hsi Chen, Pei-Zhu Shi, Xin Xie, Sweta Parik, Mélanie Planque, Sarah-Maria Fendt, Ping-Chih Ho
CD40 signal rewires fatty acid and glutamine metabolism for stimulating macrophage anti-tumorigenic functions. Nature immunology (2023)
Pu-Ste Liu, Yi-Ting Chen, Xiaoyun Li, Pei-Chun Hsueh, Sheue-Fen Tzeng, Hsi Chen, Pei-Zhu Shi, Xin Xie, Sweta Parik, Mélanie Planque, Sarah-Maria Fendt, Ping-Chih Ho
CD40 signal rewires fatty acid and glutamine metabolism for stimulating macrophage anti-tumorigenic functions. Nature immunology (2023)
Tom Van Nyen, Mélanie Planque, Lilian van Wagensveld, Joao A G Duarte, Esther A Zaal, Ali Talebi, Matteo Rossi, Pierre-René Körner, Lara Rizzotto, Stijn Moens, Wout De Wispelaere, Regina Esi Mensimah Baiden-Amissah, Gabe S Sonke, Hugo Mark Horlings, Guy Eelen, Emanuele Berardi, Johannes V Swinnen, Celia R Berkers, Peter Carmeliet, Diether Lambrechts, Ben Davidson, Reuven Agami, Sarah-Maria Fendt, Daniela Annibali, Frédéric Amant
Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancers. Nature communications 13 (1) (2022)
Ana P Gomes, Didem Ilter, Vivien Low, Stanislav Drapela, Tanya Schild, Edouard Mullarky, Julie Han, Ilaria Elia, Dorien Broekaert, Adam Rosenzweig, Michal Nagiec, Joana B Nunes, Bethany E Schaffer, Anders P Mutvei, John M Asara, Lewis C Cantley, Sarah-Maria Fendt, John Blenis
Altered propionate metabolism contributes to tumour progression and aggressiveness. Nature metabolism 4 (4) (2022)
Matteo Rossi, Patricia Altea-Manzano, Margherita Demicco, Ginevra Doglioni, Laura Bornes, Marina Fukano, Anke Vandekeere, Alejandro M Cuadros, Juan Fernández-García, Carla Riera-Domingo, Cristina Jauset, Mélanie Planque, Hamza Furkan Alkan, David Nittner, Dongmei Zuo, Lindsay A Broadfield, Sweta Parik, Antonino Alejandro Pane, Francesca Rizzollo, Gianmarco Rinaldi, Tao Zhang, Shao Thing Teoh, Arin B Aurora, Panagiotis Karras, Ines Vermeire, Dorien Broekaert, Joke Van Elsen, Maximilian Martin Ludwig Knott, Martin F Orth, Sofie Demeyer, Guy Eelen, Lacey E Dobrolecki, Ayse Bassez, Thomas Van Brussel, Karl Sotlar, Michael T Lewis, Harald Bartsch, Dana L E Vergoossen, Peter van Veelen, Peter Carmeliet, Jan Cools, Sean J Morrison, Jean-Christophe Marine, Diether Lambrechts, Massimiliano Mazzone, Gregory James Hannon, Sophia Y Lunt, Thomas G P Grünewald, Morag Park, Jacco van Rheenen, Sarah-Maria Fendt
PHGDH heterogeneity potentiates cancer cell dissemination and metastasis. Nature 605 (7911) (2022)
Gabriele Bergers, Sarah-Maria Fendt
The metabolism of cancer cells during metastasis. Nature reviews. Cancer 21 (3) (2021)
Lindsay A Broadfield, João André Gonçalves Duarte, Roberta Schmieder, Dorien Broekaert, Koen Veys, Mélanie Planque, Kim Vriens, Yasuaki Karasawa, Francesco Napolitano, Suguru Fujita, Masashi Fujii, Miki Eto, Bryan Holvoet, Pieter-Jan Martens, Juan Fernandez-Garcia, Joke Van Elsen, Jonas Dehairs, Jia Zeng, James Dooley, Rebeca Alba Rubio, Jos van Pelt, Thomas G P Grünewald, Adrian Liston, Chantal Mathieu, Christophe M Deroose, Johannes V Swinnen, Diether Lambrechts, Diego Di Bernardo, Shinya Kuroda, Katrien De Bock, Sarah-Maria Fendt
Fat Induces Glucose Metabolism in Nontransformed Liver Cells and Promotes Liver Tumorigenesis. Cancer research 81 (8) (2021)
Ruben Boon, Manoj Kumar, Tine Tricot, Ilaria Elia, Laura Ordovás, Frank Jacobs, Jennifer One, Jonathan De Smedt, Guy Eelen, Matthew Bird, Philip Roelandt, Ginevra Doglioni, Kim Vriens, Matteo Rossi, Marta Aguirre Vazquez, Thomas Vanwelden, François Chesnais, Adil El Taghdouini, Mustapha Najimi, Etienne Sokal, David Cassiman, Jan Snoeys, Mario Monshouwer, Wei-Shou Hu, Christian Lange, Peter Carmeliet, Sarah-Maria Fendt, Catherine M Verfaillie
Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines. Nature communications 11 (1) (2020)
Shauni Lien Geeraerts, Kim Rosalie Kampen, Gianmarco Rinaldi, Purvi Gupta, Mélanie Planque, Nikolaos N Louros, Elien Heylen, Kaat De Cremer, Katrijn De Brucker, Stijn Vereecke, Benno Verbelen, Pieter Vermeersch, Joost Schymkowitz, Frederic Rousseau, David Cassiman, Sarah-Maria Fendt, Arnout Voet, Bruno P A Cammue, Karin Thevissen, Kim De Keersmaecker
Repurposing the Antidepressant Sertraline as SHMT Inhibitor to Suppress Serine/Glycine Synthesis-Addicted Breast Tumor Growth. Molecular cancer therapeutics 20 (1) (2020)
Haiping Wang, Fabien Franco, Yao-Chen Tsui, Xin Xie, Marcel Philipp Trefny, Roberta Zappasodi, Syed Raza Mohmood, Juan Fernández-García, Chin-Hsien Tsai, Isabell Schulze, Florence Picard, Etienne Meylan, Roy Silverstein, Ira Goldberg, Sarah-Maria Fendt, Jedd D Wolchok, Taha Merghoub, Camilla Jandus, Alfred Zippelius, Ping-Chih Ho
CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors. Nature immunology 21 (3) (2020)
Arnaud Blomme, Catriona A Ford, Ernest Mui, Rachana Patel, Chara Ntala, Lauren E Jamieson, Mélanie Planque, Grace H McGregor, Paul Peixoto, Eric Hervouet, Colin Nixon, Mark Salji, Luke Gaughan, Elke Markert, Peter Repiscak, David Sumpton, Giovanny Rodriguez Blanco, Sergio Lilla, Jurre J Kamphorst, Duncan Graham, Karen Faulds, Gillian M MacKay, Sarah-Maria Fendt, Sara R Zanivan, Hing Y Leung
2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer. Nature communications 11 (1) (2020)
Patricia Altea-Manzano, Alejandro M Cuadros, Lindsay A Broadfield, Sarah-Maria Fendt
Nutrient metabolism and cancer in the in vivo context: a metabolic game of give and take. EMBO reports 21 (10) (2020)
Ana P Gomes, Didem Ilter, Vivien Low, Jennifer E Endress, Juan Fernández-García, Adam Rosenzweig, Tanya Schild, Dorien Broekaert, Adnan Ahmed, Melanie Planque, Ilaria Elia, Julie Han, Charles Kinzig, Edouard Mullarky, Anders P Mutvei, John Asara, Rafael de Cabo, Lewis C Cantley, Noah Dephoure, Sarah-Maria Fendt, John Blenis
Age-induced accumulation of methylmalonic acid promotes tumour progression. Nature 585 (7824) (2020)
Sarah-Maria Fendt, Christian Frezza, Ayelet Erez
Targeting Metabolic Plasticity and Flexibility Dynamics for Cancer Therapy. Cancer discovery 10 (12) (2020)
Kim Rosalie Kampen, Laura Fancello, Tiziana Girardi, Gianmarco Rinaldi, Mélanie Planque, Sergey O Sulima, Fabricio Loayza-Puch, Benno Verbelen, Stijn Vereecke, Jelle Verbeeck, Joyce Op de Beeck, Jonathan Royaert, Pieter Vermeersch, David Cassiman, Jan Cools, Reuven Agami, Mark Fiers, Sarah-Maria Fendt, Kim De Keersmaecker
Translatome analysis reveals altered serine and glycine metabolism in T-cell acute lymphoblastic leukemia cells. Nature communications 10 (1) (2019)
Tijs Vandoorne, Koen Veys, Wenting Guo, Adria Sicart, Katlijn Vints, Ann Swijsen, Matthieu Moisse, Guy Eelen, Natalia V Gounko, Laura Fumagalli, Raheem Fazal, Christine Germeys, Annelies Quaegebeur, Sarah-Maria Fendt, Peter Carmeliet, Catherine Verfaillie, Philip Van Damme, Bart Ghesquière, Katrien De Bock, Ludo Van Den Bosch
Differentiation but not ALS mutations in FUS rewires motor neuron metabolism. Nature communications 10 (1) (2019)