Lynn A Spruce

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 12

Top Topics

Dna Damage Response

Top Venues

Science advances

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Saranya Santhosh Kumar, Nima N Naseri, Sarshan R Pather, Erinc Hallacli, Alain Ndayisaba, Chris Buenaventura, Karen Acosta, Jennifer Roof, Hossein Fazelinia, Lynn A Spruce, Kelvin C Luk, Vikram Khurana, Elizabeth Rhoades, Ophir Shalem
Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons. Science advances 10 (6) (2024)
Saranya Santhosh Kumar, Nima N Naseri, Sarshan R Pather, Erinc Hallacli, Alain Ndayisaba, Chris Buenaventura, Karen Acosta, Jennifer Roof, Hossein Fazelinia, Lynn A Spruce, Kelvin C Luk, Vikram Khurana, Elizabeth Rhoades, Ophir Shalem
Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons. Science advances 10 (6) (2024)
Saranya Santhosh Kumar, Nima N Naseri, Sarshan R Pather, Erinc Hallacli, Alain Ndayisaba, Chris Buenaventura, Karen Acosta, Jennifer Roof, Hossein Fazelinia, Lynn A Spruce, Kelvin C Luk, Vikram Khurana, Elizabeth Rhoades, Ophir Shalem
Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons. Science advances 10 (6) (2024)
Saranya Santhosh Kumar, Nima N Naseri, Sarshan R Pather, Erinc Hallacli, Alain Ndayisaba, Chris Buenaventura, Karen Acosta, Jennifer Roof, Hossein Fazelinia, Lynn A Spruce, Kelvin C Luk, Vikram Khurana, Elizabeth Rhoades, Ophir Shalem
Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons. Science advances 10 (6) (2024)
Saranya Santhosh Kumar, Nima N Naseri, Sarshan R Pather, Erinc Hallacli, Alain Ndayisaba, Chris Buenaventura, Karen Acosta, Jennifer Roof, Hossein Fazelinia, Lynn A Spruce, Kelvin C Luk, Vikram Khurana, Elizabeth Rhoades, Ophir Shalem
Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons. Science advances 10 (6) (2024)
Saranya Santhosh Kumar, Nima N Naseri, Sarshan R Pather, Erinc Hallacli, Alain Ndayisaba, Chris Buenaventura, Karen Acosta, Jennifer Roof, Hossein Fazelinia, Lynn A Spruce, Kelvin C Luk, Vikram Khurana, Elizabeth Rhoades, Ophir Shalem
Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons. Science advances 10 (6) (2024)
Saranya Santhosh Kumar, Nima N Naseri, Sarshan R Pather, Erinc Hallacli, Alain Ndayisaba, Chris Buenaventura, Karen Acosta, Jennifer Roof, Hossein Fazelinia, Lynn A Spruce, Kelvin C Luk, Vikram Khurana, Elizabeth Rhoades, Ophir Shalem
Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons. Science advances 10 (6) (2024)
Asif A Dar, Dale D Kim, Scott M Gordon, Kathleen N Klinzing, Siera Rosen, Ipsita Guha, Nadia Porter, Yohaniz Ortega, Katherine S Forsyth, Jennifer Roof, Hossein Fazelinia, Lynn A Spruce, Laurence C Eisenlohr, Edward M Behrens, Paula M Oliver
c-Myc uses Cul4b to preserve genome integrity and promote antiviral CD8 + T cell immunity. Nature communications 14 (1) (2023)
Stephanie N Hurwitz, Seul K Jung, Danielle R Kobulsky, Hossein Fazelinia, Lynn A Spruce, Empar Baltasar-Pérez, Nathalie Groen, Clementina Mesaros, Peter Kurre
Neutral sphingomyelinase blockade enhances hematopoietic stem cell fitness through an integrated stress response. Blood (2023)
Scarlett Y Yang, Katharina E Hayer, Hossein Fazelinia, Lynn A Spruce, Mukta Asnani, Kathryn L Black, Ammar S Naqvi, Vinodh Pillai, Yoseph Barash, Kojo S J Elenitoba-Johnson, Andrei Thomas-Tikhonenko
FBXW7β isoform drives transcriptional activation of the proinflammatory TNF cluster in human pro-B cells. Blood advances (2022)
Asif A Dar, Keisuke Sawada, Joseph M Dybas, Emily K Moser, Emma L Lewis, Eddie Park, Hossein Fazelinia, Lynn A Spruce, Ding Hua, Steven H Seeholzer, Paula M Oliver
The E3 ubiquitin ligase Cul4b promotes CD4+ T cell expansion by aiding the repair of damaged DNA. PLoS biology 19 (2) (2021)
Joseph M Dybas, Claire E O'Leary, Hua Ding, Lynn A Spruce, Steven H Seeholzer, Paula M Oliver
Integrative proteomics reveals an increase in non-degradative ubiquitylation in activated CD4+ T cells. Nature immunology 20 (6) (2019)