Ophir Shalem

ORCID

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 21

Top Venues

University of Pennsylvania

Weizmann Institute of Science (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Pennsylvania Jan 01 2017

United States

Assistant Professor :: Genetics

Children's Hospital of Philadelphia Sep 01 2016

United States

Senior Scientist :: Center for Cellular and Molecular Therapeutics

UC Berkeley Oct 24 2014 - Aug 30 2016

United States

Visiting Scholar :: Prof. Andrew Dillin lab

Broad Institute of Harvard and MIT Jan 10 2013 - Aug 30 2016

United States

Postdoctoral Fellow :: Prof. Feng Zhang lab

Education History

Weizmann Institute of Science Apr 01 2007 - Dec 31 2012

Israel

PHD :: Molecular Genetics (labs of Prof. Tzachi Pilpel and Prof. Eran Segal)

Weizmann Institute of Science Sep 01 2004 - Mar 01 2007

Israel

MSC :: Molecular Genetics (Prof. Tzachi Pilpel lab)

Ben-Gurion University of the Negev Sep 01 2001 - Jul 31 2004

Israel

BSC :: Computer Science

Publications

Saranya Santhosh Kumar, Nima N Naseri, Sarshan R Pather, Erinc Hallacli, Alain Ndayisaba, Chris Buenaventura, Karen Acosta, Jennifer Roof, Hossein Fazelinia, Lynn A Spruce, Kelvin C Luk, Vikram Khurana, Elizabeth Rhoades, Ophir Shalem
Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons. Science advances 10 (6) (2024)
Katelyn M Sweeney, Sapanna Chantarawong, Edward M Barbieri, Greg Cajka, Matthew Liu, Lynn Spruce, Hossein Fazelinia, Bede Portz, Katie Copley, Tomer Lapidot, Lauren Duhamel, Phoebe Greenwald, Naseeb Saida, Reut Shalgi, James Shorter, Ophir Shalem
CRISPR screen for protein inclusion formation uncovers a role for SRRD in the regulation of intermediate filament dynamics and aggresome assembly. PLoS genetics 20 (2) (2024)
Katelyn M Sweeney, Sapanna Chantarawong, Edward M Barbieri, Greg Cajka, Matthew Liu, Lynn Spruce, Hossein Fazelinia, Bede Portz, Katie Copley, Tomer Lapidot, Lauren Duhamel, Phoebe Greenwald, Naseeb Saida, Reut Shalgi, James Shorter, Ophir Shalem
CRISPR screen for protein inclusion formation uncovers a role for SRRD in the regulation of intermediate filament dynamics and aggresome assembly. PLoS genetics 20 (2) (2024)
Saranya Santhosh Kumar, Nima N Naseri, Sarshan R Pather, Erinc Hallacli, Alain Ndayisaba, Chris Buenaventura, Karen Acosta, Jennifer Roof, Hossein Fazelinia, Lynn A Spruce, Kelvin C Luk, Vikram Khurana, Elizabeth Rhoades, Ophir Shalem
Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons. Science advances 10 (6) (2024)
Saranya Santhosh Kumar, Nima N Naseri, Sarshan R Pather, Erinc Hallacli, Alain Ndayisaba, Chris Buenaventura, Karen Acosta, Jennifer Roof, Hossein Fazelinia, Lynn A Spruce, Kelvin C Luk, Vikram Khurana, Elizabeth Rhoades, Ophir Shalem
Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons. Science advances 10 (6) (2024)
Dylan F Fingerman, David R O'Leary, Ava R Hansen, Thi Tran, Brooke R Harris, Rachel A DeWeerd, Katharina E Hayer, Jiayi Fan, Emily Chen, Mithila Tennakoon, Alice Meroni, Julia H Szeto, Jessica Devenport, Danielle LaVigne, Matthew D Weitzman, Ophir Shalem, Jeffrey J Bednarski, Alessandro Vindigni, Xiaolan Zhao, Abby M Green
The SMC5/6 complex prevents genotoxicity upon APOBEC3A-mediated replication stress. The EMBO journal 43 (15) (2024)
Saranya Santhosh Kumar, Nima N Naseri, Sarshan R Pather, Erinc Hallacli, Alain Ndayisaba, Chris Buenaventura, Karen Acosta, Jennifer Roof, Hossein Fazelinia, Lynn A Spruce, Kelvin C Luk, Vikram Khurana, Elizabeth Rhoades, Ophir Shalem
Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons. Science advances 10 (6) (2024)
Dylan F Fingerman, David R O'Leary, Ava R Hansen, Thi Tran, Brooke R Harris, Rachel A DeWeerd, Katharina E Hayer, Jiayi Fan, Emily Chen, Mithila Tennakoon, Alice Meroni, Julia H Szeto, Jessica Devenport, Danielle LaVigne, Matthew D Weitzman, Ophir Shalem, Jeffrey J Bednarski, Alessandro Vindigni, Xiaolan Zhao, Abby M Green
The SMC5/6 complex prevents genotoxicity upon APOBEC3A-mediated replication stress. The EMBO journal (2024)
Katelyn M Sweeney, Sapanna Chantarawong, Edward M Barbieri, Greg Cajka, Matthew Liu, Lynn Spruce, Hossein Fazelinia, Bede Portz, Katie Copley, Tomer Lapidot, Lauren Duhamel, Phoebe Greenwald, Naseeb Saida, Reut Shalgi, James Shorter, Ophir Shalem
CRISPR screen for protein inclusion formation uncovers a role for SRRD in the regulation of intermediate filament dynamics and aggresome assembly. PLoS genetics 20 (2) (2024)
Dylan F Fingerman, David R O'Leary, Ava R Hansen, Thi Tran, Brooke R Harris, Rachel A DeWeerd, Katharina E Hayer, Jiayi Fan, Emily Chen, Mithila Tennakoon, Alice Meroni, Julia H Szeto, Jessica Devenport, Danielle LaVigne, Matthew D Weitzman, Ophir Shalem, Jeffrey J Bednarski, Alessandro Vindigni, Xiaolan Zhao, Abby M Green
The SMC5/6 complex prevents genotoxicity upon APOBEC3A-mediated replication stress. The EMBO journal 43 (15) (2024)
Dylan F Fingerman, David R O'Leary, Ava R Hansen, Thi Tran, Brooke R Harris, Rachel A DeWeerd, Katharina E Hayer, Jiayi Fan, Emily Chen, Mithila Tennakoon, Alice Meroni, Julia H Szeto, Jessica Devenport, Danielle LaVigne, Matthew D Weitzman, Ophir Shalem, Jeffrey J Bednarski, Alessandro Vindigni, Xiaolan Zhao, Abby M Green
The SMC5/6 complex prevents genotoxicity upon APOBEC3A-mediated replication stress. The EMBO journal (2024)
Katelyn M Sweeney, Sapanna Chantarawong, Edward M Barbieri, Greg Cajka, Matthew Liu, Lynn Spruce, Hossein Fazelinia, Bede Portz, Katie Copley, Tomer Lapidot, Lauren Duhamel, Phoebe Greenwald, Naseeb Saida, Reut Shalgi, James Shorter, Ophir Shalem
CRISPR screen for protein inclusion formation uncovers a role for SRRD in the regulation of intermediate filament dynamics and aggresome assembly. PLoS genetics 20 (2) (2024)
Saranya Santhosh Kumar, Nima N Naseri, Sarshan R Pather, Erinc Hallacli, Alain Ndayisaba, Chris Buenaventura, Karen Acosta, Jennifer Roof, Hossein Fazelinia, Lynn A Spruce, Kelvin C Luk, Vikram Khurana, Elizabeth Rhoades, Ophir Shalem
Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons. Science advances 10 (6) (2024)
Saranya Santhosh Kumar, Nima N Naseri, Sarshan R Pather, Erinc Hallacli, Alain Ndayisaba, Chris Buenaventura, Karen Acosta, Jennifer Roof, Hossein Fazelinia, Lynn A Spruce, Kelvin C Luk, Vikram Khurana, Elizabeth Rhoades, Ophir Shalem
Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons. Science advances 10 (6) (2024)
Katelyn M Sweeney, Sapanna Chantarawong, Edward M Barbieri, Greg Cajka, Matthew Liu, Lynn Spruce, Hossein Fazelinia, Bede Portz, Katie Copley, Tomer Lapidot, Lauren Duhamel, Phoebe Greenwald, Naseeb Saida, Reut Shalgi, James Shorter, Ophir Shalem
CRISPR screen for protein inclusion formation uncovers a role for SRRD in the regulation of intermediate filament dynamics and aggresome assembly. PLoS genetics 20 (2) (2024)
Saranya Santhosh Kumar, Nima N Naseri, Sarshan R Pather, Erinc Hallacli, Alain Ndayisaba, Chris Buenaventura, Karen Acosta, Jennifer Roof, Hossein Fazelinia, Lynn A Spruce, Kelvin C Luk, Vikram Khurana, Elizabeth Rhoades, Ophir Shalem
Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons. Science advances 10 (6) (2024)
Dylan F Fingerman, David R O'Leary, Ava R Hansen, Thi Tran, Brooke R Harris, Rachel A DeWeerd, Katharina E Hayer, Jiayi Fan, Emily Chen, Mithila Tennakoon, Alice Meroni, Julia H Szeto, Jessica Devenport, Danielle LaVigne, Matthew D Weitzman, Ophir Shalem, Jeffrey J Bednarski, Alessandro Vindigni, Xiaolan Zhao, Abby M Green
The SMC5/6 complex prevents genotoxicity upon APOBEC3A-mediated replication stress. The EMBO journal 43 (15) (2024)
Katelyn M Sweeney, Sapanna Chantarawong, Edward M Barbieri, Greg Cajka, Matthew Liu, Lynn Spruce, Hossein Fazelinia, Bede Portz, Katie Copley, Tomer Lapidot, Lauren Duhamel, Phoebe Greenwald, Naseeb Saida, Reut Shalgi, James Shorter, Ophir Shalem
CRISPR screen for protein inclusion formation uncovers a role for SRRD in the regulation of intermediate filament dynamics and aggresome assembly. PLoS genetics 20 (2) (2024)
David R O'Leary, Ava R Hansen, Dylan F Fingerman, Thi Tran, Brooke R Harris, Katharina E Hayer, Mithila Tennekoon, Rachel A DeWeerd, Alice Meroni, Julia H Szeto, Matthew D Weitzman, Ophir Shalem, Jeffrey J Bednarski, Alessandro Vindigni, Abby M Green
The SMC5/6 complex is required for maintenance of genome integrity upon APOBEC3A-mediated replication stress. bioRxiv : the preprint server for biology (2023)
Yogev Sela, Jinyang Li, Shivahamy Maheswaran, Robert Norgard, Salina Yuan, Maimon Hubbi, Miriam Doepner, Jimmy P Xu, Elaine S Ho, Clementina A Mesaros, Colin Sheehan, Grace Croley, Alexander Muir, Ian A Blair, Ophir Shalem, Chi Van Dang, Ben Z Stanger
Bcl-xL Enforces a Slow-Cycling State Necessary for Survival in the Nutrient-Deprived Microenvironment of Pancreatic Cancer. Cancer research 82 (10) (2022)
Eran Segal, Feng Zhang, Xihong Lin, Gary King, Ophir Shalem, Smadar Shilo, William E Allen, Faisal Alquaddoomi, Han Altae-Tran, Simon Anders, Ran Balicer, Tal Bauman, Ximena Bonilla, Gisel Booman, Andrew T Chan, Ori Cohen, Silvano Coletti, Natalie Davidson, Yuval Dor, David A Drew, Olivier Elemento, Georgina Evans, Philip A Ewels, Joshua Gale, Amir Gavrieli, Benjamin Geiger, Yonatan Hagai Grad, Casey S Greene, Iman Hajirasouliha, Roman Jerala, Andre Kahles, Olli Kallioniemi, Ayya Keshet, Ljupco Kocarev, Gregory Landua, Tomer Meir, Aline Muller, Long H Nguyen, Matej Oresic, Svetlana Ovchinnikova, Hedi Peterson, Jana Prodanova, Jay Rajagopal, Gunnar Rätsch, Hagai Rossman, Johan Rung, Andrea Sboner, Alexandros Sigaras, Timothy D Spector, Ron Steinherz, Irene Stevens, Jaak Vilo, Paul Wilmes
Building an international consortium for tracking coronavirus health status. Nature medicine 26 (8) (2020)

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Publication Activity (10 Years)

Top Topics

Top Venues

Ophir Shalem