Marcelo Alberto Comini (Marcelo A Comini, Marcelo Comini)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 16

Top Venues

Molecules (Basel, Switzerland)

Inorganic chemistry

The Journal of biological chemistry

Biomedicines

Institut Pasteur de Montevideo

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Institut Pasteur de Montevideo Jun 08 2008

Uruguay

Principal Investigator :: Laboratory Redox Biology of Trypanosomes

Publications

Feriannys Rivas, Carolina Del Mármol, Gonzalo Scalese, Leticia Pérez Díaz, Ignacio Machado, Olivier Blacque, Fabiana Salazar, E Laura Coitiño, Diego Benítez, Andrea Medeiros, Marcelo Alberto Comini, Dinorah Gambino
Multifunctional Organometallic Compounds Active against Infective Trypanosomes: Ru(II) Ferrocenyl Derivatives with Two Different Bioactive Ligands. Inorganic chemistry 63 (25) (2024)
Feriannys Rivas, Carolina Del Mármol, Gonzalo Scalese, Leticia Pérez Díaz, Ignacio Machado, Olivier Blacque, Fabiana Salazar, E Laura Coitiño, Diego Benítez, Andrea Medeiros, Marcelo Alberto Comini, Dinorah Gambino
Multifunctional Organometallic Compounds Active against Infective Trypanosomes: Ru(II) Ferrocenyl Derivatives with Two Different Bioactive Ligands. Inorganic chemistry (2024)
Annagiulia Favaro, Giovanni Bolcato, Marcelo Alberto Comini, Stefano Moro, Massimo Bellanda, Mattia Sturlese
Drugging the Undruggable Trypanosoma brucei Monothiol Glutaredoxin 1. Molecules (Basel, Switzerland) 28 (3) (2023)
Irina Ihnatenko, Marco J Müller, Oliver C F Orban, Jens C Lindhof, Diego Benítez, Cecilia Ortíz, Estefanía Dibello, Leonardo L Seidl, Marcelo Alberto Comini, Conrad Kunick
The indole motif is essential for the antitrypanosomal activity of N5-substituted paullones. PloS one 18 (11) (2023)
Annagiulia Favaro, Giovanni Bolcato, Marcelo Alberto Comini, Stefano Moro, Massimo Bellanda, Mattia Sturlese
Drugging the Undruggable Trypanosoma brucei Monothiol Glutaredoxin 1. Molecules (Basel, Switzerland) 28 (3) (2023)
Annagiulia Favaro, Giovanni Bolcato, Marcelo Alberto Comini, Stefano Moro, Massimo Bellanda, Mattia Sturlese
Drugging the Undruggable Trypanosoma brucei Monothiol Glutaredoxin 1. Molecules (Basel, Switzerland) 28 (3) (2023)
Karen Perelmuter, Inés Tiscornia, Marcelo Alberto Comini, Mariela Bollati-Fogolín
Generation and Characterization of Stable Redox-Reporter Mammalian Cell Lines of Biotechnological Relevance. Sensors (Basel, Switzerland) 22 (4) (2022)
Mariana Pazos, Estefania Dibello, Juan Manuel Mesa, Dalibor Sames, Marcelo Alberto Comini, Gustavo Seoane, Ignacio Carrera
Iboga Inspired N -Indolylethyl-Substituted Isoquinuclidines as a Bioactive Scaffold: Chemoenzymatic Synthesis and Characterization as GDNF Releasers and Antitrypanosoma Agents. Molecules (Basel, Switzerland) 27 (3) (2022)
Olalla Barreiro-Costa, Cristina Quiroga Lozano, Erika Muñoz, Patricio Rojas-Silva, Andrea Medeiros, Marcelo Alberto Comini, Jorge Heredia-Moya
Evaluation of the Anti- Leishmania mexicana and - Trypanosoma brucei Activity and Mode of Action of 4,4'-(Arylmethylene)bis(3-methyl-1-phenyl-1 H -pyrazol-5-ol). Biomedicines 10 (8) (2022)
Andrea Medeiros, Diego Benítez, Ricarda S Korn, Vinicius C Ferreira, Exequiel E Barrera, Federico Carrión, Otto Pritsch, Sergio Pantano, Conrad Kunick, Camila I de Oliveira, Oliver C F Orban, Marcelo Alberto Comini
Mechanistic and biological characterisation of novel N5-substituted paullones targeting the biosynthesis of trypanothione in Leishmania. Journal of enzyme inhibition and medicinal chemistry 35 (1) (2021)
Juan I Alice, Carolina L Bellera, Diego Benítez, Marcelo Alberto Comini, Pablo R Duchowicz, Alan Talevi
Ensemble learning application to discover new trypanothione synthetase inhibitors. Molecular diversity 25 (3) (2021)
Cecilia Ortíz, Francesca Moraca, Marc Laverriere, Allan Michael Jordan, Niall Hamilton, Marcelo Alberto Comini
Glucose 6-Phosphate Dehydrogenase from Trypanosomes: Selectivity for Steroids and Chemical Validation in Bloodstream Trypanosoma brucei. Molecules (Basel, Switzerland) 26 (2) (2021)
Diego Benítez, Estefania Dibello, Mariana Bonilla, Marcelo Alberto Comini
A simple, robust, and affordable bioluminescent assay for drug discovery against infective African trypanosomes. Drug development research (2020)
Franco Vairoletti, Andrea Medeiros, Pablo Fontán, Jennifer Meléndrez, Carlos Tabárez, Gustavo Salinas, Jaime Franco, Marcelo Alberto Comini, Jenny Saldaña, Vojtech Jancik, Graciela Mahler, Cecilia Saiz
Synthesis of bicyclic 1,4-thiazepines as novel anti-Trypanosoma brucei brucei agents. MedChemComm 10 (8) (2019)
Bruno Manta, Matías N Möller, Mariana Bonilla, Matías Deambrosi, Karin Grunberg, Massimo Bellanda, Marcelo Alberto Comini, Gerardo Ferrer-Sueta
Kinetic studies reveal a key role of a redox-active glutaredoxin in the evolution of the thiol-redox metabolism of trypanosomatid parasites. The Journal of biological chemistry 294 (9) (2018)
Mattia Sturlese, Bruno Manta, Andrea Bertarello, Mariana Bonilla, Moreno Lelli, Barbara Zambelli, Karin Grunberg, Stefano Mammi, Marcelo Alberto Comini, Massimo Bellanda
The lineage-specific, intrinsically disordered N-terminal extension of monothiol glutaredoxin 1 from trypanosomes contains a regulatory region. Scientific reports 8 (1) (2018)

Marcelo Alberto Comini.css-eqlu8i{font-size:small;padding-left:4px;} (Marcelo A Comini, Marcelo Comini)

Publication Activity (10 Years)

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Marcelo Alberto Comini (Marcelo A Comini, Marcelo Comini)