Graciela Mahler

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 8

Top Venues

Journal of medicinal chemistry

Proteins

ACS infectious diseases

Chemical science

Universidad de la Republica Uruguay Facultad de Quimica

Universidad de la Republica Uruguay, Facultad de Quimica (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Universidad de la Republica Uruguay Facultad de Quimica Oct 01 2005

Uruguay

Professor :: Quimica Farmaceutica

Education History

Universidad de la Republica Uruguay, Facultad de Quimica Mar 02 1996 - Nov 14 2002

Uruguay

PHD :: Quimica Farmacuetica

Publications

Valentina Villamil, Maria-Agustina Rossi, Maria F Mojica, Philip Hinchliffe, Verónica Martínez, Valerie Castillo, Cecilia Saiz, Claudia Banchio, Mario A Macías, James Spencer, Robert A Bonomo, Alejandro Vila, Diego Martín Moreno, Graciela Mahler
Rational Design of Benzobisheterocycle Metallo-β-Lactamase Inhibitors: A Tricyclic Scaffold Enhances Potency against Target Enzymes. Journal of medicinal chemistry (2024)
Valentina Villamil, Maria-Agustina Rossi, Maria F Mojica, Philip Hinchliffe, Verónica Martínez, Valerie Castillo, Cecilia Saiz, Claudia Banchio, Mario A Macías, James Spencer, Robert A Bonomo, Alejandro Vila, Diego Martín Moreno, Graciela Mahler
Rational Design of Benzobisheterocycle Metallo-β-Lactamase Inhibitors: A Tricyclic Scaffold Enhances Potency against Target Enzymes. Journal of medicinal chemistry 67 (5) (2024)
Valentina Villamil, Maria-Agustina Rossi, Maria F Mojica, Philip Hinchliffe, Verónica Martínez, Valerie Castillo, Cecilia Saiz, Claudia Banchio, Mario A Macías, James Spencer, Robert A Bonomo, Alejandro Vila, Diego Martín Moreno, Graciela Mahler
Rational Design of Benzobisheterocycle Metallo-β-Lactamase Inhibitors: A Tricyclic Scaffold Enhances Potency against Target Enzymes. Journal of medicinal chemistry 67 (5) (2024)
Valentina Villamil, Franco Vairoletti, Ariel Tijman, Gonzalo López, Alejandro Peixoto de Abreu Lima, Cecilia Saiz, César Iglesias, Graciela Mahler
Novel Kinetic Resolution of Thiazolo-Benzimidazolines Using MAO Enzymes. ACS omega 8 (45) (2023)
Philip Hinchliffe, Diego Martín Moreno, Maria-Agustina Rossi, Maria F Mojica, Veronica Martinez, Valentina Villamil, Brad Spellberg, George L Drusano, Claudia Banchio, Graciela Mahler, Robert A Bonomo, Alejandro J Vila, James Spencer
2-Mercaptomethyl Thiazolidines (MMTZs) Inhibit All Metallo-β-Lactamase Classes by Maintaining a Conserved Binding Mode. ACS infectious diseases 7 (9) (2021)
Silvia Gervasoni, James Spencer, Philip Hinchliffe, Alessandro Pedretti, Franco Vairoletti, Graciela Mahler, Adrian J Mulholland
A multiscale approach to predict the binding mode of metallo beta-lactamase inhibitors. Proteins (2021)
Maria-Agustina Rossi, Veronica Martinez, Philip Hinchliffe, María Fernanda Mojica, Valerie Castillo, Diego Martín Moreno, Ryan Smith, Brad Spellberg, George L Drusano, Claudia Banchio, Robert A Bonomo, James Spencer, Alejandro J Vila, Graciela Mahler
2-Mercaptomethyl-thiazolidines use conserved aromatic-S interactions to achieve broad-range inhibition of metallo-β-lactamases. Chemical science 12 (8) (2021)
Franco Vairoletti, Andrea Medeiros, Pablo Fontán, Jennifer Meléndrez, Carlos Tabárez, Gustavo Salinas, Jaime Franco, Marcelo Alberto Comini, Jenny Saldaña, Vojtech Jancik, Graciela Mahler, Cecilia Saiz
Synthesis of bicyclic 1,4-thiazepines as novel anti-Trypanosoma brucei brucei agents. MedChemComm 10 (8) (2019)

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Publication Activity (10 Years)

Top Topics

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Graciela Mahler