Mark T Bedford (Mark Bedford)

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 39

Top Topics

Transcription Factor

Histone Deacetylase

Top Venues

Nature communications

Science immunology

The Journal of biological chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Tomer M Yaron, Brian A Joughin, Emily M Huntsman, Alexander Kerelsky, Daniel M Cizin, Benjamin M Cohen, Amit Regev, Junho Song, Neil Vasan, Ting-Yu Lin, Jose M Orozco, Christina Schoenherr, Cari Sagum, Mark T Bedford, R Max Wynn, Shih-Chia Tso, David T Chuang, Lei Li, Shawn Shun-Cheng Li, Pau Creixell, Konstantin Krismer, Mina Takegami, Harin Lee, Bin Zhang, Jingyi Lu, Ian Cossentino, Sean D Landry, Mohamed Uduman, John Blenis, Olivier Elemento, Margaret C Frame, Peter V Hornbeck, Lewis C Cantley, Benjamin E Turk, Micheal B Yaffe, Jared L Johnson
The intrinsic substrate specificity of the human tyrosine kinome. Nature (2024)
Ioanna Tiniakou, Pei-Feng Hsu, Lorena S Lopez-Zepeda, Görkem Garipler, Eduardo Esteva, Nicholas M Adams, Geunhyo Jang, Chetna Soni, Colleen M Lau, Fan Liu, Alireza Khodadadi-Jamayran, Tori C Rodrick, Drew R Jones, Aristotelis Tsirigos, Uwe Ohler, Mark T Bedford, Stephen D Nimer, Vesa Kaartinen, Esteban Orlando Mazzoni, Boris Reizis
Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation. Science immunology 9 (94) (2024)
Ioanna Tiniakou, Pei-Feng Hsu, Lorena S Lopez-Zepeda, Görkem Garipler, Eduardo Esteva, Nicholas M Adams, Geunhyo Jang, Chetna Soni, Colleen M Lau, Fan Liu, Alireza Khodadadi-Jamayran, Tori C Rodrick, Drew R Jones, Aristotelis Tsirigos, Uwe Ohler, Mark T Bedford, Stephen D Nimer, Vesa Kaartinen, Esteban Orlando Mazzoni, Boris Reizis
Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation. Science immunology 9 (94) (2024)
Tomer M Yaron, Brian A Joughin, Emily M Huntsman, Alexander Kerelsky, Daniel M Cizin, Benjamin M Cohen, Amit Regev, Junho Song, Neil Vasan, Ting-Yu Lin, Jose M Orozco, Christina Schoenherr, Cari Sagum, Mark T Bedford, R Max Wynn, Shih-Chia Tso, David T Chuang, Lei Li, Shawn Shun-Cheng Li, Pau Creixell, Konstantin Krismer, Mina Takegami, Harin Lee, Bin Zhang, Jingyi Lu, Ian Cossentino, Sean D Landry, Mohamed Uduman, John Blenis, Olivier Elemento, Margaret C Frame, Peter V Hornbeck, Lewis C Cantley, Benjamin E Turk, Micheal B Yaffe, Jared L Johnson
The intrinsic substrate specificity of the human tyrosine kinome. Nature 629 (8014) (2024)
Ioanna Tiniakou, Pei-Feng Hsu, Lorena S Lopez-Zepeda, Görkem Garipler, Eduardo Esteva, Nicholas M Adams, Geunhyo Jang, Chetna Soni, Colleen M Lau, Fan Liu, Alireza Khodadadi-Jamayran, Tori C Rodrick, Drew R Jones, Aristotelis Tsirigos, Uwe Ohler, Mark T Bedford, Stephen D Nimer, Vesa Kaartinen, Esteban Orlando Mazzoni, Boris Reizis
Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation. Science immunology 9 (94) (2024)
Ioanna Tiniakou, Pei-Feng Hsu, Lorena S Lopez-Zepeda, Görkem Garipler, Eduardo Esteva, Nicholas M Adams, Geunhyo Jang, Chetna Soni, Colleen M Lau, Fan Liu, Alireza Khodadadi-Jamayran, Tori C Rodrick, Drew R Jones, Aristotelis Tsirigos, Uwe Ohler, Mark T Bedford, Stephen D Nimer, Vesa Kaartinen, Esteban Orlando Mazzoni, Boris Reizis
Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation. Science immunology 9 (94) (2024)
Tomer M Yaron, Brian A Joughin, Emily M Huntsman, Alexander Kerelsky, Daniel M Cizin, Benjamin M Cohen, Amit Regev, Junho Song, Neil Vasan, Ting-Yu Lin, Jose M Orozco, Christina Schoenherr, Cari Sagum, Mark T Bedford, R Max Wynn, Shih-Chia Tso, David T Chuang, Lei Li, Shawn Shun-Cheng Li, Pau Creixell, Konstantin Krismer, Mina Takegami, Harin Lee, Bin Zhang, Jingyi Lu, Ian Cossentino, Sean D Landry, Mohamed Uduman, John Blenis, Olivier Elemento, Margaret C Frame, Peter V Hornbeck, Lewis C Cantley, Benjamin E Turk, Micheal B Yaffe, Jared L Johnson
The intrinsic substrate specificity of the human tyrosine kinome. Nature 629 (8014) (2024)
Ioanna Tiniakou, Pei-Feng Hsu, Lorena S Lopez-Zepeda, Görkem Garipler, Eduardo Esteva, Nicholas M Adams, Geunhyo Jang, Chetna Soni, Colleen M Lau, Fan Liu, Alireza Khodadadi-Jamayran, Tori C Rodrick, Drew R Jones, Aristotelis Tsirigos, Uwe Ohler, Mark T Bedford, Stephen D Nimer, Vesa Kaartinen, Esteban Orlando Mazzoni, Boris Reizis
Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation. Science immunology 9 (94) (2024)
Tomer M Yaron, Brian A Joughin, Emily M Huntsman, Alexander Kerelsky, Daniel M Cizin, Benjamin M Cohen, Amit Regev, Junho Song, Neil Vasan, Ting-Yu Lin, Jose M Orozco, Christina Schoenherr, Cari Sagum, Mark T Bedford, R Max Wynn, Shih-Chia Tso, David T Chuang, Lei Li, Shawn Shun-Cheng Li, Pau Creixell, Konstantin Krismer, Mina Takegami, Harin Lee, Bin Zhang, Jingyi Lu, Ian Cossentino, Sean D Landry, Mohamed Uduman, John Blenis, Olivier Elemento, Margaret C Frame, Peter V Hornbeck, Lewis C Cantley, Benjamin E Turk, Micheal B Yaffe, Jared L Johnson
The intrinsic substrate specificity of the human tyrosine kinome. Nature 629 (8014) (2024)
Tomer M Yaron, Brian A Joughin, Emily M Huntsman, Alexander Kerelsky, Daniel M Cizin, Benjamin M Cohen, Amit Regev, Junho Song, Neil Vasan, Ting-Yu Lin, Jose M Orozco, Christina Schoenherr, Cari Sagum, Mark T Bedford, R Max Wynn, Shih-Chia Tso, David T Chuang, Lei Li, Shawn Shun-Cheng Li, Pau Creixell, Konstantin Krismer, Mina Takegami, Harin Lee, Bin Zhang, Jingyi Lu, Ian Cossentino, Sean D Landry, Mohamed Uduman, John Blenis, Olivier Elemento, Margaret C Frame, Peter V Hornbeck, Lewis C Cantley, Benjamin E Turk, Micheal B Yaffe, Jared L Johnson
The intrinsic substrate specificity of the human tyrosine kinome. Nature 629 (8014) (2024)
Ioanna Tiniakou, Pei-Feng Hsu, Lorena S Lopez-Zepeda, Görkem Garipler, Eduardo Esteva, Nicholas M Adams, Geunhyo Jang, Chetna Soni, Colleen M Lau, Fan Liu, Alireza Khodadadi-Jamayran, Tori C Rodrick, Drew R Jones, Aristotelis Tsirigos, Uwe Ohler, Mark T Bedford, Stephen D Nimer, Vesa Kaartinen, Esteban Orlando Mazzoni, Boris Reizis
Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation. Science immunology 9 (94) (2024)
Ioanna Tiniakou, Pei-Feng Hsu, Lorena S Lopez-Zepeda, Görkem Garipler, Eduardo Esteva, Nicholas M Adams, Geunhyo Jang, Chetna Soni, Colleen M Lau, Fan Liu, Alireza Khodadadi-Jamayran, Tori C Rodrick, Drew R Jones, Aristotelis Tsirigos, Uwe Ohler, Mark T Bedford, Stephen D Nimer, Vesa Kaartinen, Esteban Orlando Mazzoni, Boris Reizis
Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation. Science immunology 9 (94) (2024)
Guozhen Gao, Simone Hausmann, Natasha M Flores, Ana Morales Benitez, Jianjun Shen, Xiaojie Yang, Maria D Person, Sitaram Gayatri, Donghang Cheng, Yue Lu, Bin Liu, Pawel K Mazur, Mark T Bedford
The NFIB/CARM1 partnership is a driver in preclinical models of small cell lung cancer. Nature communications 14 (1) (2023)
Yalong Wang, Mark T Bedford
Effectors and effects of arginine methylation. Biochemical Society transactions (2023)
Guozhen Gao, Simone Hausmann, Natasha M Flores, Ana Morales Benitez, Jianjun Shen, Xiaojie Yang, Maria D Person, Sitaram Gayatri, Donghang Cheng, Yue Lu, Bin Liu, Pawel K Mazur, Mark T Bedford
The NFIB/CARM1 partnership is a driver in preclinical models of small cell lung cancer. Nature communications 14 (1) (2023)
Guozhen Gao, Simone Hausmann, Natasha M Flores, Ana Morales Benitez, Jianjun Shen, Xiaojie Yang, Maria D Person, Sitaram Gayatri, Donghang Cheng, Yue Lu, Bin Liu, Pawel K Mazur, Mark T Bedford
The NFIB/CARM1 partnership is a driver in preclinical models of small cell lung cancer. Nature communications 14 (1) (2023)
Guozhen Gao, Simone Hausmann, Natasha M Flores, Ana Morales Benitez, Jianjun Shen, Xiaojie Yang, Maria D Person, Sitaram Gayatri, Donghang Cheng, Yue Lu, Bin Liu, Pawel K Mazur, Mark T Bedford
The NFIB/CARM1 partnership is a driver in preclinical models of small cell lung cancer. Nature communications 14 (1) (2023)
Guozhen Gao, Simone Hausmann, Natasha M Flores, Ana Morales Benitez, Jianjun Shen, Xiaojie Yang, Maria D Person, Sitaram Gayatri, Donghang Cheng, Yue Lu, Bin Liu, Pawel K Mazur, Mark T Bedford
The NFIB/CARM1 partnership is a driver in preclinical models of small cell lung cancer. Nature communications 14 (1) (2023)
Guozhen Gao, Simone Hausmann, Natasha M Flores, Ana Morales Benitez, Jianjun Shen, Xiaojie Yang, Maria D Person, Sitaram Gayatri, Donghang Cheng, Yue Lu, Bin Liu, Pawel K Mazur, Mark T Bedford
The NFIB/CARM1 partnership is a driver in preclinical models of small cell lung cancer. Nature communications 14 (1) (2023)
Guozhen Gao, Simone Hausmann, Natasha M Flores, Ana Morales Benitez, Jianjun Shen, Xiaojie Yang, Maria D Person, Sitaram Gayatri, Donghang Cheng, Yue Lu, Bin Liu, Pawel K Mazur, Mark T Bedford
The NFIB/CARM1 partnership is a driver in preclinical models of small cell lung cancer. Nature communications 14 (1) (2023)
Yanli Liu, Aman Iqbal, Weiguo Li, Zuyao Ni, Yalong Wang, Jurupula Ramprasad, Karan Joshua Abraham, Mengmeng Zhang, Dorothy Yanling Zhao, Su Qin, Peter Loppnau, Honglv Jiang, Xinghua Guo, Peter J Brown, Xuechu Zhen, Guoqiang Xu, Karim Mekhail, Xingyue Ji, Mark T Bedford, Jack F Greenblatt, Jinrong Min
A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II. Nature communications 13 (1) (2022)
Andrew Fedoriw, Leilei Shi, Shane O'Brien, Kimberly N Smitheman, Yunfei Wang, Jiakai Hou, Christian Sherk, Satyajit Rajapurkar, Jenny Laraio, Leila J Williams, Chunyu Xu, Guangchun Han, Qin Feng, Mark T Bedford, Linghua Wang, Olena Barbash, Ryan G Kruger, Patrick Hwu, Helai P Mohammad, Weiyi Peng
Inhibiting Type I Arginine Methyltransferase Activity Promotes T Cell-Mediated Antitumor Immune Responses. Cancer immunology research 10 (4) (2022)
Jianji Chen, John Horton, Cari Sagum, Jujun Zhou, Xiaodong Cheng, Mark T Bedford
Histone H3 N-terminal mimicry drives a novel network of methyl-effector interactions. The Biochemical journal 478 (10) (2021)
Fen Yang, Jianji Chen, Bin Liu, Guozhen Gao, Manu Sebastian, Collene Jeter, Jianjun Shen, Maria D Person, Mark T Bedford
SPINDOC binds PARP1 to facilitate PARylation. Nature communications 12 (1) (2021)
Ziying Han, Shantoshini Dash, Cari A Sagum, Gordon Ruthel, Chaitanya Kumar Jaladanki, Corbett T Berry, Michael P Schwoerer, Nina M Harty, Bruce D Freedman, Mark T Bedford, Hao Fan, Sachdev S Sidhu, Marius Sudol, Olena Shtanko, Ronald N Harty
Modular mimicry and engagement of the Hippo pathway by Marburg virus VP40: Implications for filovirus biology and budding. PLoS pathogens 16 (1) (2020)
Wei He, Liang Zhang, Oscar D Villarreal, Rongjie Fu, Ella Bedford, Jingzhuang Dou, Anish Y Patel, Mark T Bedford, Xiaobing Shi, Jiameng Dan, Blaine Bartholomew, Han Xu
Author Correction: De novo identification of essential protein domains from CRISPR-Cas9 tiling-sgRNA knockout screens. Nature communications 11 (1) (2020)
Swarnalatha Manickavinayaham, Renier Vélez-Cruz, Anup K Biswas, Ella Bedford, Brianna J Klein, Tatiana G Kutateladze, Bin Liu, Mark T Bedford, David G Johnson
E2F1 acetylation directs p300/CBP-mediated histone acetylation at DNA double-strand breaks to facilitate repair. Nature communications 10 (1) (2019)
Sreedevi Avasarala, Pei-Ying Wu, Samia Q Khan, Su Yanlin, Michelle Van Scoyk, Jianqiang Bao, Alessandra Di Lorenzo, Odile David, Mark T Bedford, Vineet Gupta, Robert A Winn, Rama Kamesh Bikkavilli
PRMT6 Promotes Lung Tumor Progression via the Alternate Activation of Tumor-Associated Macrophages. Molecular cancer research : MCR 18 (1) (2019)
Praveen Rajendran, Gavin Johnson, Li Li, Ying-Shiuan Chen, Mohaiza Dashwood, Nhung Nguyen, Ahmet Ulusan, Furkan Ertem, Mutian Zhang, Jia Li, Deqiang Sun, Yun Huang, Shan Wang, Hon-Chiu Leung, David Lieberman, Laura Beaver, Emily Ho, Mark T Bedford, Kyle Chang, Eduardo Vilar, Roderick Dashwood
Acetylation of CCAR2 Establishes a BET/BRD9 Acetyl Switch in Response to Combined Deacetylase and Bromodomain Inhibition. Cancer research 79 (5) (2019)
Lee Roth, Jean Wakim, Elad Wasserman, Moran Shalev, Esther Arman, Merle Stein, Vlad Brumfeld, Cari A Sagum, Mark T Bedford, Jan P Tuckermann, Ari Elson
Phosphorylation of the phosphatase PTPROt at Tyr399 is a molecular switch that controls osteoclast activity and bone mass in vivo. Science signaling 12 (563) (2019)
Wei He, Liang Zhang, Oscar D Villarreal, Rongjie Fu, Ella Bedford, Jingzhuang Dou, Anish Y Patel, Mark T Bedford, Xiaobing Shi, Jiameng Dan, Blaine Bartholomew, Han Xu
De novo identification of essential protein domains from CRISPR-Cas9 tiling-sgRNA knockout screens. Nature communications 10 (1) (2019)
Mark T Bedford
Screening for histone codebreakers. The Journal of biological chemistry 293 (35) (2019)
Ziying Han, Michael P Schwoerer, Philip Hicks, Jingjing Liang, Gordon Ruthel, Corbett T Berry, Bruce D Freedman, Cari A Sagum, Mark T Bedford, Sachdev S Sidhu, Marius Sudol, Ronald N Harty
Host Protein BAG3 is a Negative Regulator of Lassa VLP Egress. Diseases (Basel, Switzerland) 6 (3) (2018)
Donghang Cheng, Vidyasiri Vemulapalli, Yue Lu, Jianjun Shen, Sayura Aoyagi, Christopher J Fry, Yanzhong Yang, Charles E Foulds, Fabio Stossi, Lindsey S Treviño, Michael A Mancini, Bert W O' Malley, Cheryl L Walker, Thomas G Boyer, Mark T Bedford
CARM1 methylates MED12 to regulate its RNA-binding ability. Life science alliance 1 (5) (2018)
Jianqiang Bao, Alessandra Di Lorenzo, Kevin Lin, Yue Lu, Yi Zhong, Manu M Sebastian, William J Muller, Yanzhong Yang, Mark T Bedford
Mouse Models of Overexpression Reveal Distinct Oncogenic Roles for Different Type I Protein Arginine Methyltransferases. Cancer research 79 (1) (2018)
Narkhyun Bae, Monica Viviano, Xiaonan Su, Jie Lv, Donghang Cheng, Cari Sagum, Sabrina Castellano, Xue Bai, Claire Johnson, Mahmoud Ibrahim Khalil, Jianjun Shen, Kaifu Chen, Haitao Li, Gianluca Sbardella, Mark T Bedford
Developing Spindlin1 small-molecule inhibitors by using protein microarrays. Nature chemical biology 13 (7) (2017)
Narkhyun Bae, Min Gao, Xu Li, Tolkappiyan Premkumar, Gianluca Sbardella, Junjie Chen, Mark T Bedford
A transcriptional coregulator, SPIN·DOC, attenuates the coactivator activity of Spindlin1. The Journal of biological chemistry 292 (51) (2017)
Mohammad B Hossain, Rehnuma Shifat, David G Johnson, Mark T Bedford, Konrad R Gabrusiewicz, Nahir Cortes-Santiago, Xuemei Luo, Zhimin Lu, Ravesanker Ezhilarasan, Erik P Sulman, Hong Jiang, Shawn S C Li, Frederick F Lang, Jessica Tyler, Mien-Chie Hung, Juan Fueyo, Candelaria Gomez-Manzano
TIE2-mediated tyrosine phosphorylation of H4 regulates DNA damage response by recruiting ABL1. Science advances 2 (4) (2016)
Alexsandra B Espejo, Guozhen Gao, Karynne Black, Sitaram Gayatri, Nicolas Veland, Jeesun Kim, Taiping Chen, Marius Sudol, Cheryl K Walker, Mark T Bedford
PRMT5 C-terminal Phosphorylation Modulates a 14-3-3/PDZ Interaction Switch. The Journal of biological chemistry 292 (6) (2016)
Andrea Hadjikyriacou, Yanzhong Yang, Alexsandra B Espejo, Mark T Bedford, Steven G Clarke
Unique Features of Human Protein Arginine Methyltransferase 9 (PRMT9) and Its Substrate RNA Splicing Factor SF3B2. The Journal of biological chemistry 290 (27) (2015)