Micheal B Yaffe (Michael Yaffe, Michael B Yaffe)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 59

Top Topics

Top Venues

Nature communications

Science signaling

Cancer research

This page only lists publications with an associated author ORCID identifier.

Publications

Tomer M Yaron, Brian A Joughin, Emily M Huntsman, Alexander Kerelsky, Daniel M Cizin, Benjamin M Cohen, Amit Regev, Junho Song, Neil Vasan, Ting-Yu Lin, Jose M Orozco, Christina Schoenherr, Cari Sagum, Mark T Bedford, R Max Wynn, Shih-Chia Tso, David T Chuang, Lei Li, Shawn Shun-Cheng Li, Pau Creixell, Konstantin Krismer, Mina Takegami, Harin Lee, Bin Zhang, Jingyi Lu, Ian Cossentino, Sean D Landry, Mohamed Uduman, John Blenis, Olivier Elemento, Margaret C Frame, Peter V Hornbeck, Lewis C Cantley, Benjamin E Turk, Micheal B Yaffe, Jared L Johnson
The intrinsic substrate specificity of the human tyrosine kinome. Nature (2024)
Bert van de Kooij, Fenna J van der Wal, Magdalena B Rother, Wouter W Wiegant, Pau Creixell, Merula Stout, Brian A Joughin, Julia Vornberger, Matthias Altmeyer, Marcel A T M van Vugt, Micheal B Yaffe, Haico van Attikum
The Fanconi anemia core complex promotes CtIP-dependent end resection to drive homologous recombination at DNA double-strand breaks. Nature communications 15 (1) (2024)
Ting Dong, Guangan Hu, Zhongqi Fan, Huirui Wang, Yinghui Gao, Sisi Wang, Hao Xu, Micheal B Yaffe, Matthew G Vander Heiden, Guo-Yue Lv, Jianzhu Chen
Activation of GPR3-β-arrestin2-PKM2 pathway in Kupffer cells stimulates glycolysis and inhibits obesity and liver pathogenesis. Nature communications 15 (1) (2024)
Bert van de Kooij, Fenna J van der Wal, Magdalena B Rother, Wouter W Wiegant, Pau Creixell, Merula Stout, Brian A Joughin, Julia Vornberger, Matthias Altmeyer, Marcel A T M van Vugt, Micheal B Yaffe, Haico van Attikum
The Fanconi anemia core complex promotes CtIP-dependent end resection to drive homologous recombination at DNA double-strand breaks. Nature communications 15 (1) (2024)
Michela Chiappa, Alessandra Decio, Luca Guarrera, Ilaria Mengoli, Anju Karki, Divora Yemane, Carmen Ghilardi, Eugenio Scanziani, Simone Canesi, Maria C Barbera, Ilaria Craparotta, Marco Bolis, Robert Fruscio, Chiara Grasselli, Tommaso Ceruti, Massimo Zucchetti, Jesse C Patterson, Robin A Lu, Micheal B Yaffe, Maya Ridinger, Giovanna Damia, Federica Guffanti
Onvansertib treatment overcomes olaparib resistance in high-grade ovarian carcinomas. Cell death & disease 15 (7) (2024)
Tomer M Yaron, Brian A Joughin, Emily M Huntsman, Alexander Kerelsky, Daniel M Cizin, Benjamin M Cohen, Amit Regev, Junho Song, Neil Vasan, Ting-Yu Lin, Jose M Orozco, Christina Schoenherr, Cari Sagum, Mark T Bedford, R Max Wynn, Shih-Chia Tso, David T Chuang, Lei Li, Shawn Shun-Cheng Li, Pau Creixell, Konstantin Krismer, Mina Takegami, Harin Lee, Bin Zhang, Jingyi Lu, Ian Cossentino, Sean D Landry, Mohamed Uduman, John Blenis, Olivier Elemento, Margaret C Frame, Peter V Hornbeck, Lewis C Cantley, Benjamin E Turk, Micheal B Yaffe, Jared L Johnson
The intrinsic substrate specificity of the human tyrosine kinome. Nature 629 (8014) (2024)
Ting Dong, Guangan Hu, Zhongqi Fan, Huirui Wang, Yinghui Gao, Sisi Wang, Hao Xu, Micheal B Yaffe, Matthew G Vander Heiden, Guo-Yue Lv, Jianzhu Chen
Activation of GPR3-β-arrestin2-PKM2 pathway in Kupffer cells stimulates glycolysis and inhibits obesity and liver pathogenesis. Nature communications 15 (1) (2024)
Michela Chiappa, Alessandra Decio, Luca Guarrera, Ilaria Mengoli, Anju Karki, Divora Yemane, Carmen Ghilardi, Eugenio Scanziani, Simone Canesi, Maria C Barbera, Ilaria Craparotta, Marco Bolis, Robert Fruscio, Chiara Grasselli, Tommaso Ceruti, Massimo Zucchetti, Jesse C Patterson, Robin A Lu, Micheal B Yaffe, Maya Ridinger, Giovanna Damia, Federica Guffanti
Onvansertib treatment overcomes olaparib resistance in high-grade ovarian carcinomas. Cell death & disease 15 (7) (2024)
Michela Chiappa, Alessandra Decio, Luca Guarrera, Ilaria Mengoli, Anju Karki, Divora Yemane, Carmen Ghilardi, Eugenio Scanziani, Simone Canesi, Maria C Barbera, Ilaria Craparotta, Marco Bolis, Robert Fruscio, Chiara Grasselli, Tommaso Ceruti, Massimo Zucchetti, Jesse C Patterson, Robin A Lu, Micheal B Yaffe, Maya Ridinger, Giovanna Damia, Federica Guffanti
Onvansertib treatment overcomes olaparib resistance in high-grade ovarian carcinomas. Cell death & disease 15 (7) (2024)
Ting Dong, Guangan Hu, Zhongqi Fan, Huirui Wang, Yinghui Gao, Sisi Wang, Hao Xu, Micheal B Yaffe, Matthew G Vander Heiden, Guo-Yue Lv, Jianzhu Chen
Activation of GPR3-β-arrestin2-PKM2 pathway in Kupffer cells stimulates glycolysis and inhibits obesity and liver pathogenesis. Nature communications 15 (1) (2024)
Tomer M Yaron, Brian A Joughin, Emily M Huntsman, Alexander Kerelsky, Daniel M Cizin, Benjamin M Cohen, Amit Regev, Junho Song, Neil Vasan, Ting-Yu Lin, Jose M Orozco, Christina Schoenherr, Cari Sagum, Mark T Bedford, R Max Wynn, Shih-Chia Tso, David T Chuang, Lei Li, Shawn Shun-Cheng Li, Pau Creixell, Konstantin Krismer, Mina Takegami, Harin Lee, Bin Zhang, Jingyi Lu, Ian Cossentino, Sean D Landry, Mohamed Uduman, John Blenis, Olivier Elemento, Margaret C Frame, Peter V Hornbeck, Lewis C Cantley, Benjamin E Turk, Micheal B Yaffe, Jared L Johnson
The intrinsic substrate specificity of the human tyrosine kinome. Nature 629 (8014) (2024)
Tomer M Yaron, Brian A Joughin, Emily M Huntsman, Alexander Kerelsky, Daniel M Cizin, Benjamin M Cohen, Amit Regev, Junho Song, Neil Vasan, Ting-Yu Lin, Jose M Orozco, Christina Schoenherr, Cari Sagum, Mark T Bedford, R Max Wynn, Shih-Chia Tso, David T Chuang, Lei Li, Shawn Shun-Cheng Li, Pau Creixell, Konstantin Krismer, Mina Takegami, Harin Lee, Bin Zhang, Jingyi Lu, Ian Cossentino, Sean D Landry, Mohamed Uduman, John Blenis, Olivier Elemento, Margaret C Frame, Peter V Hornbeck, Lewis C Cantley, Benjamin E Turk, Micheal B Yaffe, Jared L Johnson
The intrinsic substrate specificity of the human tyrosine kinome. Nature 629 (8014) (2024)
Xiao-Kang Lun, Kuanwei Sheng, Xueyang Yu, Ching Yeung Lam, Gokul Gowri, Matthew Serrata, Yunhao Zhai, Hanquan Su, Jingyi Luan, Youngeun Kim, Donald E Ingber, Hartland Warren Jackson, Micheal B Yaffe, Peng Yin
Signal amplification by cyclic extension enables high-sensitivity single-cell mass cytometry. Nature biotechnology (2024)
Tomer M Yaron, Brian A Joughin, Emily M Huntsman, Alexander Kerelsky, Daniel M Cizin, Benjamin M Cohen, Amit Regev, Junho Song, Neil Vasan, Ting-Yu Lin, Jose M Orozco, Christina Schoenherr, Cari Sagum, Mark T Bedford, R Max Wynn, Shih-Chia Tso, David T Chuang, Lei Li, Shawn Shun-Cheng Li, Pau Creixell, Konstantin Krismer, Mina Takegami, Harin Lee, Bin Zhang, Jingyi Lu, Ian Cossentino, Sean D Landry, Mohamed Uduman, John Blenis, Olivier Elemento, Margaret C Frame, Peter V Hornbeck, Lewis C Cantley, Benjamin E Turk, Micheal B Yaffe, Jared L Johnson
The intrinsic substrate specificity of the human tyrosine kinome. Nature 629 (8014) (2024)
Ting Dong, Guangan Hu, Zhongqi Fan, Huirui Wang, Yinghui Gao, Sisi Wang, Hao Xu, Micheal B Yaffe, Matthew G Vander Heiden, Guo-Yue Lv, Jianzhu Chen
Activation of GPR3-β-arrestin2-PKM2 pathway in Kupffer cells stimulates glycolysis and inhibits obesity and liver pathogenesis. Nature communications 15 (1) (2024)
Bert van de Kooij, Fenna J van der Wal, Magdalena B Rother, Wouter W Wiegant, Pau Creixell, Merula Stout, Brian A Joughin, Julia Vornberger, Matthias Altmeyer, Marcel A T M van Vugt, Micheal B Yaffe, Haico van Attikum
The Fanconi anemia core complex promotes CtIP-dependent end resection to drive homologous recombination at DNA double-strand breaks. Nature communications 15 (1) (2024)
Ting Dong, Guangan Hu, Zhongqi Fan, Huirui Wang, Yinghui Gao, Sisi Wang, Hao Xu, Micheal B Yaffe, Matthew G Vander Heiden, Guo-Yue Lv, Jianzhu Chen
Activation of GPR3-β-arrestin2-PKM2 pathway in Kupffer cells stimulates glycolysis and inhibits obesity and liver pathogenesis. Nature communications 15 (1) (2024)
Ting Dong, Guangan Hu, Zhongqi Fan, Huirui Wang, Yinghui Gao, Sisi Wang, Hao Xu, Micheal B Yaffe, Matthew G Vander Heiden, Guo-Yue Lv, Jianzhu Chen
Activation of GPR3-β-arrestin2-PKM2 pathway in Kupffer cells stimulates glycolysis and inhibits obesity and liver pathogenesis. Nature communications 15 (1) (2024)
Jared L Johnson, Tomer M Yaron, Emily M Huntsman, Alexander Kerelsky, Junho Song, Amit Regev, Ting-Yu Lin, Katarina Liberatore, Daniel M Cizin, Benjamin M Cohen, Neil Vasan, Yilun Ma, Konstantin Krismer, Jaylissa Torres Robles, Bert van de Kooij, Anne E van Vlimmeren, Nicole Andrée-Busch, Norbert F Käufer, Maxim V Dorovkov, Alexey G Ryazanov, Yuichiro Takagi, Edward R Kastenhuber, Marcus DaSilva Goncalves, Benjamin D Hopkins, Olivier Elemento, Dylan J Taatjes, Alexandre Maucuer, Akio Yamashita, Alexei Degterev, Mohamed Uduman, Jingyi Lu, Sean D Landry, Bin Zhang, Ian Cossentino, Rune Linding, John Blenis, Peter V Hornbeck, Benjamin E Turk, Micheal B Yaffe, Lewis C Cantley
An atlas of substrate specificities for the human serine/threonine kinome. Nature 613 (7945) (2023)
Jared L Johnson, Tomer M Yaron, Emily M Huntsman, Alexander Kerelsky, Junho Song, Amit Regev, Ting-Yu Lin, Katarina Liberatore, Daniel M Cizin, Benjamin M Cohen, Neil Vasan, Yilun Ma, Konstantin Krismer, Jaylissa Torres Robles, Bert van de Kooij, Anne E van Vlimmeren, Nicole Andrée-Busch, Norbert F Käufer, Maxim V Dorovkov, Alexey G Ryazanov, Yuichiro Takagi, Edward R Kastenhuber, Marcus DaSilva Goncalves, Benjamin D Hopkins, Olivier Elemento, Dylan J Taatjes, Alexandre Maucuer, Akio Yamashita, Alexei Degterev, Mohamed Uduman, Jingyi Lu, Sean D Landry, Bin Zhang, Ian Cossentino, Rune Linding, John Blenis, Peter V Hornbeck, Benjamin E Turk, Micheal B Yaffe, Lewis C Cantley
An atlas of substrate specificities for the human serine/threonine kinome. Nature 613 (7945) (2023)
Jared L Johnson, Tomer M Yaron, Emily M Huntsman, Alexander Kerelsky, Junho Song, Amit Regev, Ting-Yu Lin, Katarina Liberatore, Daniel M Cizin, Benjamin M Cohen, Neil Vasan, Yilun Ma, Konstantin Krismer, Jaylissa Torres Robles, Bert van de Kooij, Anne E van Vlimmeren, Nicole Andrée-Busch, Norbert F Käufer, Maxim V Dorovkov, Alexey G Ryazanov, Yuichiro Takagi, Edward R Kastenhuber, Marcus DaSilva Goncalves, Benjamin D Hopkins, Olivier Elemento, Dylan J Taatjes, Alexandre Maucuer, Akio Yamashita, Alexei Degterev, Mohamed Uduman, Jingyi Lu, Sean D Landry, Bin Zhang, Ian Cossentino, Rune Linding, John Blenis, Peter V Hornbeck, Benjamin E Turk, Micheal B Yaffe, Lewis C Cantley
An atlas of substrate specificities for the human serine/threonine kinome. Nature 613 (7945) (2023)
Jared L Johnson, Tomer M Yaron, Emily M Huntsman, Alexander Kerelsky, Junho Song, Amit Regev, Ting-Yu Lin, Katarina Liberatore, Daniel M Cizin, Benjamin M Cohen, Neil Vasan, Yilun Ma, Konstantin Krismer, Jaylissa Torres Robles, Bert van de Kooij, Anne E van Vlimmeren, Nicole Andrée-Busch, Norbert F Käufer, Maxim V Dorovkov, Alexey G Ryazanov, Yuichiro Takagi, Edward R Kastenhuber, Marcus DaSilva Goncalves, Benjamin D Hopkins, Olivier Elemento, Dylan J Taatjes, Alexandre Maucuer, Akio Yamashita, Alexei Degterev, Mohamed Uduman, Jingyi Lu, Sean D Landry, Bin Zhang, Ian Cossentino, Rune Linding, John Blenis, Peter V Hornbeck, Benjamin E Turk, Micheal B Yaffe, Lewis C Cantley
An atlas of substrate specificities for the human serine/threonine kinome. Nature 613 (7945) (2023)
Jared L Johnson, Tomer M Yaron, Emily M Huntsman, Alexander Kerelsky, Junho Song, Amit Regev, Ting-Yu Lin, Katarina Liberatore, Daniel M Cizin, Benjamin M Cohen, Neil Vasan, Yilun Ma, Konstantin Krismer, Jaylissa Torres Robles, Bert van de Kooij, Anne E van Vlimmeren, Nicole Andrée-Busch, Norbert F Käufer, Maxim V Dorovkov, Alexey G Ryazanov, Yuichiro Takagi, Edward R Kastenhuber, Marcus DaSilva Goncalves, Benjamin D Hopkins, Olivier Elemento, Dylan J Taatjes, Alexandre Maucuer, Akio Yamashita, Alexei Degterev, Mohamed Uduman, Jingyi Lu, Sean D Landry, Bin Zhang, Ian Cossentino, Rune Linding, John Blenis, Peter V Hornbeck, Benjamin E Turk, Micheal B Yaffe, Lewis C Cantley
An atlas of substrate specificities for the human serine/threonine kinome. Nature 613 (7945) (2023)
Benjamin L Green, Lauren A Gamble, Laurence P Diggs, Darryl Nousome, Jesse C Patterson, Brian A Joughin, Billel Gasmi, Stephanie C Lux, Sarah G Samaranayake, Markku M Miettinen, Martha Quezado, Jonathan M Hernandez, Micheal B Yaffe, Jeremy Lee Davis
Early immune changes support signet ring cell dormancy in CDH1-driven hereditary diffuse gastric carcinogenesis. Molecular cancer research : MCR (2023)
Jared L Johnson, Tomer M Yaron, Emily M Huntsman, Alexander Kerelsky, Junho Song, Amit Regev, Ting-Yu Lin, Katarina Liberatore, Daniel M Cizin, Benjamin M Cohen, Neil Vasan, Yilun Ma, Konstantin Krismer, Jaylissa Torres Robles, Bert van de Kooij, Anne E van Vlimmeren, Nicole Andrée-Busch, Norbert F Käufer, Maxim V Dorovkov, Alexey G Ryazanov, Yuichiro Takagi, Edward R Kastenhuber, Marcus DaSilva Goncalves, Benjamin D Hopkins, Olivier Elemento, Dylan J Taatjes, Alexandre Maucuer, Akio Yamashita, Alexei Degterev, Mohamed Uduman, Jingyi Lu, Sean D Landry, Bin Zhang, Ian Cossentino, Rune Linding, John Blenis, Peter V Hornbeck, Benjamin E Turk, Micheal B Yaffe, Lewis C Cantley
An atlas of substrate specificities for the human serine/threonine kinome. Nature 613 (7945) (2023)
H Holden Thorp, Micheal B Yaffe
Seeing is great, understanding is better. Science signaling 16 (767) (2023)
Jared L Johnson, Tomer M Yaron, Emily M Huntsman, Alexander Kerelsky, Junho Song, Amit Regev, Ting-Yu Lin, Katarina Liberatore, Daniel M Cizin, Benjamin M Cohen, Neil Vasan, Yilun Ma, Konstantin Krismer, Jaylissa Torres Robles, Bert van de Kooij, Anne E van Vlimmeren, Nicole Andrée-Busch, Norbert F Käufer, Maxim V Dorovkov, Alexey G Ryazanov, Yuichiro Takagi, Edward R Kastenhuber, Marcus DaSilva Goncalves, Benjamin D Hopkins, Olivier Elemento, Dylan J Taatjes, Alexandre Maucuer, Akio Yamashita, Alexei Degterev, Mohamed Uduman, Jingyi Lu, Sean D Landry, Bin Zhang, Ian Cossentino, Rune Linding, John Blenis, Peter V Hornbeck, Benjamin E Turk, Micheal B Yaffe, Lewis C Cantley
An atlas of substrate specificities for the human serine/threonine kinome. Nature 613 (7945) (2023)
H Holden Thorp, Micheal B Yaffe
Seeing is great, understanding is better. Science signaling 16 (767) (2023)
Jared L Johnson, Tomer M Yaron, Emily M Huntsman, Alexander Kerelsky, Junho Song, Amit Regev, Ting-Yu Lin, Katarina Liberatore, Daniel M Cizin, Benjamin M Cohen, Neil Vasan, Yilun Ma, Konstantin Krismer, Jaylissa Torres Robles, Bert van de Kooij, Anne E van Vlimmeren, Nicole Andrée-Busch, Norbert F Käufer, Maxim V Dorovkov, Alexey G Ryazanov, Yuichiro Takagi, Edward R Kastenhuber, Marcus DaSilva Goncalves, Benjamin D Hopkins, Olivier Elemento, Dylan J Taatjes, Alexandre Maucuer, Akio Yamashita, Alexei Degterev, Mohamed Uduman, Jingyi Lu, Sean D Landry, Bin Zhang, Ian Cossentino, Rune Linding, John Blenis, Peter V Hornbeck, Benjamin E Turk, Micheal B Yaffe, Lewis C Cantley
An atlas of substrate specificities for the human serine/threonine kinome. Nature 613 (7945) (2023)
Jung-Kuei Chen, Karl A Merrick, Yi Wen Kong, Anita Izrael-Tomasevic, George Eng, Erika D Handly, Jesse C Patterson, Ian G Cannell, Lucia Suarez-Lopez, Aaron M Hosios, Anh Dinh, Donald S Kirkpatrick, Kebing Yu, Christopher M Rose, Jonathan M Hernandez, Haeun Hwangbo, Adam C Palmer, Matthew G Vander Heiden, Ömer H Yilmaz, Micheal B Yaffe
An RNA Damage Response Network Mediates the Lethality of 5-FU in Clinically Relevant Tumor Types. bioRxiv : the preprint server for biology (2023)
Angus I Lamond, Ivan Đikić, André Nussenzweig, Christoph W Müller, Janet M Thornton, Micheal B Yaffe
The mission to ensure continued funding for excellent basic research. EMBO reports (2023)
Jared L Johnson, Tomer M Yaron, Emily M Huntsman, Alexander Kerelsky, Junho Song, Amit Regev, Ting-Yu Lin, Katarina Liberatore, Daniel M Cizin, Benjamin M Cohen, Neil Vasan, Yilun Ma, Konstantin Krismer, Jaylissa Torres Robles, Bert van de Kooij, Anne E van Vlimmeren, Nicole Andrée-Busch, Norbert F Käufer, Maxim V Dorovkov, Alexey G Ryazanov, Yuichiro Takagi, Edward R Kastenhuber, Marcus DaSilva Goncalves, Benjamin D Hopkins, Olivier Elemento, Dylan J Taatjes, Alexandre Maucuer, Akio Yamashita, Alexei Degterev, Mohamed Uduman, Jingyi Lu, Sean D Landry, Bin Zhang, Ian Cossentino, Rune Linding, John Blenis, Peter V Hornbeck, Benjamin E Turk, Micheal B Yaffe, Lewis C Cantley
An atlas of substrate specificities for the human serine/threonine kinome. Nature 613 (7945) (2023)
H Holden Thorp, Micheal B Yaffe
Seeing is great, understanding is better. Science signaling 16 (767) (2023)
Jared L Johnson, Tomer M Yaron, Emily M Huntsman, Alexander Kerelsky, Junho Song, Amit Regev, Ting-Yu Lin, Katarina Liberatore, Daniel M Cizin, Benjamin M Cohen, Neil Vasan, Yilun Ma, Konstantin Krismer, Jaylissa Torres Robles, Bert van de Kooij, Anne E van Vlimmeren, Nicole Andrée-Busch, Norbert F Käufer, Maxim V Dorovkov, Alexey G Ryazanov, Yuichiro Takagi, Edward R Kastenhuber, Marcus DaSilva Goncalves, Benjamin D Hopkins, Olivier Elemento, Dylan J Taatjes, Alexandre Maucuer, Akio Yamashita, Alexei Degterev, Mohamed Uduman, Jingyi Lu, Sean D Landry, Bin Zhang, Ian Cossentino, Rune Linding, John Blenis, Peter V Hornbeck, Benjamin E Turk, Micheal B Yaffe, Lewis C Cantley
An atlas of substrate specificities for the human serine/threonine kinome. Nature 613 (7945) (2023)
Jung-Kuei Chen, Karl A Merrick, Yi Wen Kong, Anita Izrael-Tomasevic, George Eng, Erika D Handly, Jesse C Patterson, Ian G Cannell, Lucia Suarez-Lopez, Aaron M Hosios, Anh Dinh, Donald S Kirkpatrick, Kebing Yu, Christopher M Rose, Jonathan M Hernandez, Haeun Hwangbo, Adam C Palmer, Matthew G Vander Heiden, Ömer H Yilmaz, Micheal B Yaffe
An RNA Damage Response Network Mediates the Lethality of 5-FU in Clinically Relevant Tumor Types. bioRxiv : the preprint server for biology (2023)
Jared L Johnson, Tomer M Yaron, Emily M Huntsman, Alexander Kerelsky, Junho Song, Amit Regev, Ting-Yu Lin, Katarina Liberatore, Daniel M Cizin, Benjamin M Cohen, Neil Vasan, Yilun Ma, Konstantin Krismer, Jaylissa Torres Robles, Bert van de Kooij, Anne E van Vlimmeren, Nicole Andrée-Busch, Norbert F Käufer, Maxim V Dorovkov, Alexey G Ryazanov, Yuichiro Takagi, Edward R Kastenhuber, Marcus DaSilva Goncalves, Benjamin D Hopkins, Olivier Elemento, Dylan J Taatjes, Alexandre Maucuer, Akio Yamashita, Alexei Degterev, Mohamed Uduman, Jingyi Lu, Sean D Landry, Bin Zhang, Ian Cossentino, Rune Linding, John Blenis, Peter V Hornbeck, Benjamin E Turk, Micheal B Yaffe, Lewis C Cantley
An atlas of substrate specificities for the human serine/threonine kinome. Nature 613 (7945) (2023)
Jared L Johnson, Tomer M Yaron, Emily M Huntsman, Alexander Kerelsky, Junho Song, Amit Regev, Ting-Yu Lin, Katarina Liberatore, Daniel M Cizin, Benjamin M Cohen, Neil Vasan, Yilun Ma, Konstantin Krismer, Jaylissa Torres Robles, Bert van de Kooij, Anne E van Vlimmeren, Nicole Andrée-Busch, Norbert F Käufer, Maxim V Dorovkov, Alexey G Ryazanov, Yuichiro Takagi, Edward R Kastenhuber, Marcus DaSilva Goncalves, Benjamin D Hopkins, Olivier Elemento, Dylan J Taatjes, Alexandre Maucuer, Akio Yamashita, Alexei Degterev, Mohamed Uduman, Jingyi Lu, Sean D Landry, Bin Zhang, Ian Cossentino, Rune Linding, John Blenis, Peter V Hornbeck, Benjamin E Turk, Micheal B Yaffe, Lewis C Cantley
An atlas of substrate specificities for the human serine/threonine kinome. Nature (2023)
Jared L Johnson, Tomer M Yaron, Emily M Huntsman, Alexander Kerelsky, Junho Song, Amit Regev, Ting-Yu Lin, Katarina Liberatore, Daniel M Cizin, Benjamin M Cohen, Neil Vasan, Yilun Ma, Konstantin Krismer, Jaylissa Torres Robles, Bert van de Kooij, Anne E van Vlimmeren, Nicole Andrée-Busch, Norbert F Käufer, Maxim V Dorovkov, Alexey G Ryazanov, Yuichiro Takagi, Edward R Kastenhuber, Marcus DaSilva Goncalves, Benjamin D Hopkins, Olivier Elemento, Dylan J Taatjes, Alexandre Maucuer, Akio Yamashita, Alexei Degterev, Mohamed Uduman, Jingyi Lu, Sean D Landry, Bin Zhang, Ian Cossentino, Rune Linding, John Blenis, Peter V Hornbeck, Benjamin E Turk, Micheal B Yaffe, Lewis C Cantley
An atlas of substrate specificities for the human serine/threonine kinome. Nature (2023)
Siva Sankari, Vignesh M P Babu, Ke Bian, Areej Alhhazmi, Mary C Andorfer, Dante M Avalos, Tyler A Smith, Kwan Yoon, Catherine L Drennan, Micheal B Yaffe, Sebastian Lourido, Graham C Walker
A haem-sequestering plant peptide promotes iron uptake in symbiotic bacteria. Nature microbiology 7 (9) (2022)
Jesse C Patterson, Andreas Varkaris, Peter J P Croucher, Maya Ridinger, Susan L Dalrymple, Mannan Nouri, Fang Xie, Shohreh Varmeh, Oliver Jonas, Matthew A Whitman, Sen Chen, Saleh Rashed, Lovemore Makusha, Jun Luo, John T Isaacs, Mark G Erlander, David J Einstein, Steven P Balk, Micheal B Yaffe
Plk1 Inhibitors and Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling. Cancer research (2022)
Bert van de Kooij, Alex Kruswick, Haico van Attikum, Micheal B Yaffe
Multi-pathway DNA-repair reporters reveal competition between end-joining, single-strand annealing and homologous recombination at Cas9-induced DNA double-strand breaks. Nature communications 13 (1) (2022)
Ganapathy Sriram, Tiffany R Emmons, Lauren E Milling, Darrell J Irvine, Micheal B Yaffe
Immunogenic cell stress and injury versus immunogenic cell death: implications for improving cancer treatment with immune checkpoint blockade. Molecular & cellular oncology 9 (1) (2022)
Tiffany R Emmons, Thejaswini Giridharan, Kelly L Singel, Anm Nazmul H Khan, Jason Ricciuti, Kaitlyn Howard, Stephanie L Silva-Del Toro, Ivy L Debreceni, Cathelijn E M Aarts, Mieke C Brouwer, Sora Suzuki, Taco W Kuijpers, Ilse Jongerius, Lee-Ann H Allen, Viviana P Ferreira, Anna Schubart, Holger Sellner, Jörg Eder, Steven M Holland, Sanjay Ram, James Arthur Lederer, Kevin H Eng, Kirsten B Moysich, Kunle Odunsi, Micheal B Yaffe, Emese Zsiros, Brahm H Segal
Mechanisms Driving Neutrophil-Induced T-cell Immunoparalysis in Ovarian Cancer. Cancer immunology research 9 (7) (2021)
Ganapathy Sriram, Lauren E Milling, Jung-Kuei Chen, Yi Wen Kong, Brian A Joughin, Wuhbet Abraham, Susanne Swartwout, Erika D Handly, Darrell J Irvine, Micheal B Yaffe
The injury response to DNA damage in live tumor cells promotes antitumor immunity. Science signaling 14 (705) (2021)
David Hymel, Kohei Tsuji, Robert A Grant, Ramesh M Chingle, Dominique L Kunciw, Micheal B Yaffe, Terrence R Burke
Design and synthesis of a new orthogonally protected glutamic acid analog and its use in the preparation of high affinity polo-like kinase 1 polo-box domain - binding peptide macrocycles. Organic & biomolecular chemistry 19 (36) (2021)
Daniel C Lim, Vladimir Joukov, T Justin Rettenmaier, Akiko Kumagai, William G Dunphy, James A Wells, Micheal B Yaffe
Redox priming promotes Aurora A activation during mitosis. Science signaling 13 (641) (2020)
Fred C Lam, Yi Wen Kong, Micheal B Yaffe
Inducing DNA damage through R-loops to kill cancer cells. Molecular & cellular oncology 8 (1) (2020)
Christopher D Barrett, Hunter B Moore, Ernest E Moore, Robert C McIntyre, Peter K Moore, John Burke, Fei Hua, Joshua Apgar, Daniel S Talmor, Angela Sauaia, Deborah R Liptzin, Livia A Veress, Micheal B Yaffe
Fibrinolytic therapy for refractory COVID-19 acute respiratory distress syndrome: Scientific rationale and review. Research and practice in thrombosis and haemostasis 4 (4) (2020)
Yi Wen Kong, Erik C Dreaden, Sandra Morandell, Wen Zhou, Sanjeev S Dhara, Ganapathy Sriram, Fred C Lam, Jesse C Patterson, Mohiuddin Quadir, Anh Dinh, Kevin E Shopsowitz, Shohreh Varmeh, Ömer H Yilmaz, Stephen J Lippard, H Christian Reinhardt, Michael T Hemann, Paula T Hammond, Micheal B Yaffe
Enhancing chemotherapy response through augmented synthetic lethality by co-targeting nucleotide excision repair and cell-cycle checkpoints. Nature communications 11 (1) (2020)
Christopher D Barrett, Micheal B Yaffe
COVID-19: All the wrong moves in all the wrong places. Science signaling 13 (649) (2020)
Fred C Lam, Yi Wen Kong, Qiuying Huang, Tu-Lan Vu Han, Amanda D Maffa, Ekkehard M Kasper, Micheal B Yaffe
BRD4 prevents the accumulation of R-loops and protects against transcription-replication collision events and DNA damage. Nature communications 11 (1) (2020)
Joon Ho Kang, Georgios Katsikis, Zhaoqi Li, Kiera M Sapp, Max A Stockslager, Daniel Lim, Matthew G Vander Heiden, Micheal B Yaffe, Scott R Manalis, Teemu P Miettinen
Monitoring and modeling of lymphocytic leukemia cell bioenergetics reveals decreased ATP synthesis during cell division. Nature communications 11 (1) (2020)
Daniel C Lim, Vladimir Joukov, Micheal B Yaffe
Are redox changes a critical switch for mitotic progression? Molecular & cellular oncology 7 (6) (2020)
Nasir Haider, Previn Dutt, Bert van de Kooij, Jason Ho, Luis Palomero, Miguel Angel Pujana, Micheal B Yaffe, Vuk Stambolic
NEK10 tyrosine phosphorylates p53 and controls its transcriptional activity. Oncogene 39 (30) (2020)
Bert van de Kooij, Pau Creixell, Anne van Vlimmeren, Brian A Joughin, Chad J Miller, Nasir Haider, Craig D Simpson, Rune Linding, Vuk Stambolic, Benjamin E Turk, Micheal B Yaffe
Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs. eLife 8 (2019)
Canan Kasikara, Viralkumar Davra, David Calianese, Ke Geng, Thomas E Spires, Michael Quigley, Michael Wichroski, Ganapathy Sriram, Lucia Suarez-Lopez, Micheal B Yaffe, Sergei V Kotenko, Mariana S De Lorenzo, Raymond B Birge
Pan-TAM Tyrosine Kinase Inhibitor BMS-777607 Enhances Anti-PD-1 mAb Efficacy in a Murine Model of Triple-Negative Breast Cancer. Cancer research 79 (10) (2019)
Nazanin Rohani, Liangliang Hao, Maria S Alexis, Brian A Joughin, Konstantin Krismer, Mira N Moufarrej, Anthony R Soltis, Douglas A Lauffenburger, Micheal B Yaffe, Christopher B Burge, Sangeeta N Bhatia, Frank B Gertler
Acidification of Tumor at Stromal Boundaries Drives Transcriptome Alterations Associated with Aggressive Phenotypes. Cancer research 79 (8) (2019)
Micheal B Yaffe
Why geneticists stole cancer research even though cancer is primarily a signaling disease. Science signaling 12 (565) (2019)
Ozan Alkan, Birgit Schoeberl, Millie Shah, Alexander Koshkaryev, Tim Heinemann, Daryl C Drummond, Micheal B Yaffe, Andreas Raue
Modeling chemotherapy-induced stress to identify rational combination therapies in the DNA damage response pathway. Science signaling 11 (540) (2018)