Markku Varjosalo

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 48

Top Topics

Transcription Factor

Tyrosine Kinase

Capillary Electrophoresis

Top Venues

Nature structural & molecular biology

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Kaisa-Mari Launonen, Vera Varis, Niina Aaltonen, Einari A Niskanen, Markku Varjosalo, Jorma J Palvimo, Jorma J Palvimo
Central role of SUMOylation in the regulation of chromatin interactions and transcriptional outputs of the androgen receptor in prostate cancer cells. Nucleic acids research (2024)
Saara Laulumaa, Esa-Pekka Kumpula, Juha T Huiskonen, Markku Varjosalo
Author Correction: Structure and interactions of the endogenous human Commander complex. Nature structural & molecular biology (2024)
Saara Laulumaa, Esa-Pekka Kumpula, Juha T Huiskonen, Markku Varjosalo
Author Correction: Structure and interactions of the endogenous human Commander complex. Nature structural & molecular biology (2024)
Xiaonan Liu, Lawrence Abad, Lopamudra Chatterjee, Ileana M Cristea, Markku Varjosalo
Mapping protein-protein interactions by mass spectrometry. Mass spectrometry reviews (2024)
Giovanna Dashi, Markku Varjosalo
Oncofusions - shaping cancer care. The oncologist (2024)
Leo Meriranta, Selma Sorri, Kanutte Huse, Xiaonan Liu, Ivana Spasevska, Sadia Zafar, Iftekhar Chowdury, Olli Dufva, Eerika Sahlberg, Luka Tandaric, Marja-Liisa Karjalainen-Lindsberg, Marko M Hyytiäinen, Markku Varjosalo, June Helen Myklebust, Sirpa Leppa
Disruption of KLHL6 Fuels Oncogenic Antigen Receptor Signaling in B-Cell Lymphoma. Blood cancer discovery 5 (5) (2024)
Lisa M Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo
Interaction network of human early embryonic transcription factors. EMBO reports 25 (3) (2024)
Xiaonan Liu, Lawrence Abad, Lopamudra Chatterjee, Ileana M Cristea, Markku Varjosalo
Mapping protein-protein interactions by mass spectrometry. Mass spectrometry reviews (2024)
Saara Laulumaa, Esa-Pekka Kumpula, Juha T Huiskonen, Markku Varjosalo
Structure and interactions of the endogenous human Commander complex. Nature structural & molecular biology (2024)
Leo Meriranta, Selma Sorri, Kanutte Huse, Xiaonan Liu, Ivana Spasevska, Sadia Zafar, Iftekhar Chowdury, Olli Dufva, Eerika Sahlberg, Luka Tandaric, Marja-Liisa Karjalainen-Lindsberg, Marko M Hyytiäinen, Markku Varjosalo, June Helen Myklebust, Sirpa Leppa
Disruption of KLHL6 Fuels Oncogenic Antigen Receptor Signaling in B-cell Lymphoma. Blood cancer discovery (2024)
Saara Laulumaa, Esa-Pekka Kumpula, Juha T Huiskonen, Markku Varjosalo
Structure and interactions of the endogenous human Commander complex. Nature structural & molecular biology (2024)
Lisa M Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo
Interaction network of human early embryonic transcription factors. EMBO reports (2024)
Saara Laulumaa, Esa-Pekka Kumpula, Juha T Huiskonen, Markku Varjosalo
Structure and interactions of the endogenous human Commander complex. Nature structural & molecular biology (2024)
Lisa M Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo
Interaction network of human early embryonic transcription factors. EMBO reports 25 (3) (2024)
Saara Laulumaa, Esa-Pekka Kumpula, Juha T Huiskonen, Markku Varjosalo
Structure and interactions of the endogenous human Commander complex. Nature structural & molecular biology 31 (6) (2024)
Lisa M Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo
Interaction network of human early embryonic transcription factors. EMBO reports 25 (3) (2024)
Saara Laulumaa, Esa-Pekka Kumpula, Juha T Huiskonen, Markku Varjosalo
Structure and interactions of the endogenous human Commander complex. Nature structural & molecular biology 31 (6) (2024)
Saara Laulumaa, Esa-Pekka Kumpula, Juha T Huiskonen, Markku Varjosalo
Structure and interactions of the endogenous human Commander complex. Nature structural & molecular biology (2024)
Saara Laulumaa, Esa-Pekka Kumpula, Juha T Huiskonen, Markku Varjosalo
Structure and interactions of the endogenous human Commander complex. Nature structural & molecular biology 31 (6) (2024)
Rafael Moliner, Mykhailo Girych, Cecilia A Brunello, Vera Kovaleva, Caroline Biojone, Giray Enkavi, Lina Antenucci, Erik F Kot, Sergey A Goncharuk, Katja Kaurinkoski, Mirjami Kuutti, Senem Merve Fred, Lauri V Elsilä, Sven Sakson, Cecilia Cannarozzo, Cassiano Ricardo Alves Faria Diniz, Nina Seiffert, Anna Rubiolo, Hele Haapaniemi, Elsa Meshi, Elina Nagaeva, Tiina J Öhman, Tomasz Róg, Esko Kankuri, Marçal Vilar, Markku Varjosalo, Esa R Korpi, Perttu Permi, Konstantin S Mineev, Mart Saarma, Ilpo Vattulainen, Plinio Cabrera Casarotto, Eero Castren
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB. Nature neuroscience 26 (6) (2023)
Kari Salokas, Giovanna Dashi, Markku Varjosalo
Decoding Oncofusions: Unveiling Mechanisms, Clinical Impact, and Prospects for Personalized Cancer Therapies. Cancers 15 (14) (2023)
Sevgi Kostel Bal, Sarah Giuliani, Jana Block, Peter Repiscak, Christoph Hafemeister, Tala Shahin, Nurhan Kasap, Bernhard Ransmayr, Yirun Miao, Cheryl van de Wetering, Alexandra Frohne, Raul Jimenez-Heredia, Michael K Schuster, Samaneh Zoghi, Vanessa Hertlein, Marini Thian, Aleksandr Bykov, Royala Babayeva, Sevgi Bilgic Eltan, Elif Karakoc-Aydiner, Lisa Ellen Shaw, Iftekhar Chowdury, Markku Varjosalo, Rafael Jose Argüello, Matthias Farlik, Ahmet Ozen, Edgar Albert Ernst Serfling, Loïc Dupré, Christoph Bock, Florian Halbritter, J Thomas Hannich, Irinka Castanon, Michael J Kraakman, Safa Barış, Kaan Boztug
Biallelic NFATC1 mutations cause an inborn error of immunity with impaired CD8+ T-cell function and perturbed glycolysis. Blood (2023)
Matias Kinnunen, Xiaonan Liu, Elina H Niemelä, Tiina J Öhman, Lisa M Gawriyski, Kari Salokas, Salla Keskitalo, Markku Varjosalo
The Impact of ETV6-NTRK3 Oncogenic Gene Fusions on Molecular and Signaling Pathway Alterations. Cancers 15 (17) (2023)
Larisa Chernyaeva, Giorgio Ratti, Laura Teirilä, Satoshi Fudo, Uni Rankka, Anssi Pelkonen, Paula Korhonen, Katarzyna Leskinen, Salla Keskitalo, Kari Salokas, Christina Gkolfinopoulou, Katrina E Crompton, Matti Javanainen, Lotta J Happonen, Markku Varjosalo, Tarja Malm, Ville Leinonen, Angeliki Chroni, Päivi Saavalainen, Seppo Meri, Tommi Kajander, Adam J M Wollman, Eija Nissilä, Karita Haapasalo
Reduced binding of apoE4 to complement factor H promotes amyloid-β oligomerization and neuroinflammation. EMBO reports (2023)
Salla Keskitalo, Markku Varjosalo
Single-cell omics techniques to elucidate cell-to-cell variability in signaling cascades involved in human diseases. Expert review of proteomics (2023)
Sini Luoma, Philipp Sergeev, Komal Kumar Javarappa, Tiina J Öhman, Markku Varjosalo, Marjaana Säily, Pekka Anttila, Marja Sankelo, Partanen Anu, Anne Nihtinen, Caroline A Heckman, Raija Silvennoinen
Deep Immune Profiling of Multiple Myeloma at Diagnosis and under Lenalidomide Maintenance Therapy. Cancers 15 (9) (2023)
Sini Luoma, Philipp Sergeev, Komal Kumar Javarappa, Tiina J Öhman, Markku Varjosalo, Marjaana Säily, Pekka Anttila, Marja Sankelo, Partanen Anu, Anne Nihtinen, Caroline A Heckman, Raija Silvennoinen
Deep Immune Profiling of Multiple Myeloma at Diagnosis and under Lenalidomide Maintenance Therapy. Cancers 15 (9) (2023)
Tala Shahin, Daniel Mayr, Mohamed R Shoeb, Hye Sun Kuehn, Birgit Hoeger, Sarah Giuliani, Lisa M Gawriyski, Özlem Yüce Petronczki, Jérôme Hadjadj, Sevgi Köstel Bal, Samaneh Zoghi, Matthias Haimel, Raul Jimenez Heredia, David Boutboul, Michael P Triebwasser, Fanny Rialland, Nathalie Costedoat Chalumeau, Pierre Quartier Dit Maire, Stuart G Tangye, Thomas A Fleisher, Nima Rezaei, Neil Romberg, Sylvain Latour, Markku Varjosalo, Florian Halbritter, Frédéric Rieux-Laucat, Irinka Castanon, Sergio D Rosenzweig, Kaan Boztug
Identification of germline monoallelic mutations in IKZF2 in patients with immune dysregulation. Blood advances 6 (7) (2022)
Julia Elzanowska, Laura Berrocal, Beatriz García-Peláez, Marta Vives-Usano, Beatriz Passos Sebo, Joana Maia, Silvia Batista, Jaakko S Teppo, Markku Varjosalo, Maria Carolina Strano Moraes, Miguel Ángel Molina-Vila, Bruno Costa Silva
Defining Optimal Conditions for Tumor Extracellular Vesicle DNA Extraction for Mutation Profiling. Cancers 14 (13) (2022)
Katri Vaparanta, Anne Jokilammi, Mahlet Tamirat, Johannes A M Merilahti, Kari Salokas, Markku Varjosalo, Johanna Ivaska, Mark S Johnson, Klaus Elenius
An extracellular receptor tyrosine kinase motif orchestrating intracellular STAT activation. Nature communications 13 (1) (2022)
Salla Mattola, Kari Salokas, Vesa Aho, Elina Mäntylä, Sami Salminen, Satu Hakanen, Einari A Niskanen, Julija Svirskaite, Teemu O Ihalainen, Kari J Airenne, Minna U Kaikkonen, Colin R Parrish, Markku Varjosalo, Maija Vihinen-Ranta
Parvovirus nonstructural protein 2 interacts with chromatin-regulating cellular proteins. PLoS pathogens 18 (4) (2022)
Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdury, Lisa M Gawriyski, Salla Keskitalo, Markku Varjosalo
Physical and functional interactome atlas of human receptor tyrosine kinases. EMBO reports 23 (6) (2022)
Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo
Human transcription factor protein interaction networks. Nature communications 13 (1) (2022)
Zlatka Plavec, Aušra Domanska, Xiaonan Liu, Pia Laine, Lars Paulin, Markku Varjosalo, Petri Auvinen, Sharon Grayer Wolf, Maria Anastasina, Sarah Jane Butcher
SARS-CoV-2 Production, Purification Methods and UV Inactivation for Proteomics and Structural Studies. Viruses 14 (9) (2022)
Ave Eesmaa, Li-Ying Yu, Helka Göös, Tatiana Danilova, Kristofer Nõges, Emmi Pakarinen, Markku Varjosalo, Maria Lindahl, Päivi Lindholm, Mart Saarma
CDNF Interacts with ER Chaperones and Requires UPR Sensors to Promote Neuronal Survival. International journal of molecular sciences 23 (16) (2022)
Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras A Redchuk, Mariia Bogacheva, Kari Salokas, Ina Poehner, Tiina J Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa M Gawriyski, Salla Keskitalo, Maria Kristina Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo
SARS-CoV-2-host proteome interactions for antiviral drug discovery. Molecular systems biology 17 (11) (2021)
Ganna Reint, Zhuokun Li, Kornel Labun, Salla Keskitalo, Inkeri Soppa, Katariina Mamia, Eero Tolo, Monika Szymanska, Leonardo A Meza-Zepeda, Susanne Lorenz, Artur Cieslar-Pobuda, Xian Hu, Diana L Bordin, Judith Staerk, Eivind Valen, Bernhard Schmierer, Markku Varjosalo, Jussi Taipale, Emma Haapaniemi
Rapid genome editing by CRISPR-Cas9-POLD3 fusion. eLife 10 (2021)
Tala Shahin, Hye Sun Kuehn, Mohamed R Shoeb, Lisa M Gawriyski, Sarah Giuliani, Peter Repiscak, Birgit Hoeger, Özlem Yüce Petronczki, Sevgi Köstel Bal, Samaneh Zoghi, Jasmin Dmytrus, Davide Seruggia, Irinka Castanon, Nima Rezaei, Markku Varjosalo, Florian Halbritter, Sergio D Rosenzweig, Kaan Boztug
Germline biallelic mutation affecting the transcription factor Helios causes pleiotropic defects of immunity. Science immunology 6 (65) (2021)
Saara Laulumaa, Markku Varjosalo
Commander Complex-A Multifaceted Operator in Intracellular Signaling and Cargo. Cells 10 (12) (2021)
Iivo Hetemäki, Meri Kaustio, Matias Kinnunen, Nelli Heikkilä, Salla Keskitalo, Kirsten H A Nowlan, Simo Miettinen, Joona Sarkkinen, Virpi Glumoff, Noora Andersson, Kaisa Kettunen, Reetta Vanhanen, Katariina Nurmi, Kari K Eklund, Johannes Dunkel, Mikko I Mäyränpää, Heinrich Schlums, T Petteri Arstila, Kai Kisand, Yenan T Bryceson, Pärt Peterson, Ulla Otava, Jaana Syrjänen, Janna Saarela, Markku Varjosalo, Eliisa Kekäläinen
Loss-of-function mutation in IKZF2 leads to immunodeficiency with dysregulated germinal center reactions and reduction of MAIT cells. Science immunology 6 (65) (2021)
Swarnalok De, Maija Pollari, Markku Varjosalo, Kristiina Mäkinen
Association of host protein VARICOSE with HCPro within a multiprotein complex is crucial for RNA silencing suppression, translation, encapsidation and systemic spread of potato virus A infection. PLoS pathogens 16 (10) (2020)
Xiaonan Liu, Kari Salokas, Rigbe G Weldatsadik, Lisa Gawriyski, Markku Varjosalo
Combined proximity labeling and affinity purification-mass spectrometry workflow for mapping and visualizing protein interaction networks. Nature protocols 15 (10) (2020)
Sampo Kukkurainen, Latifeh Azizi, Pingfeng Zhang, Marie-Claude Jacquier, Mo Baikoghli, Magdaléna von Essen, Anne Tuukkanen, Mikko Laitaoja, Xiaonan Liu, Rolle Rahikainen, Adam Orłowski, Janne Jänis, Juha A E Määttä, Markku Varjosalo, Ilpo Vattulainen, Tomasz Róg, Dmitri Svergun, R Holland Cheng, Jinhua Wu, Vesa Pekka Hytönen, Bernhard Wehrle-Haller
The F1 loop of the talin head domain acts as a gatekeeper in integrin activation and clustering. Journal of cell science 133 (19) (2020)
Tahira Anwar, Xiaonan Liu, Taina Suntio, Annika Marjamäki, Joanna Biazik, Edmond Y W Chan, Markku Varjosalo, Eeva-Liisa Eskelinen
ER-Targeted Beclin 1 Supports Autophagosome Biogenesis in the Absence of ULK1 and ULK2 Kinases. Cells 8 (5) (2019)
Ditte Marie Brix, Siri Amanda Tvingsholm, Malene Bredahl Hansen, Knut Bundgaard Clemmensen, Tiina Ohman, Valentina Siino, Matteo Lambrughi, Klaus Hansen, Pietri Puustinen, Irina Gromova, Peter James, Elena Papaleo, Markku Varjosalo, José Moreira, Marja Jäättelä, Tuula Kallunki
Release of transcriptional repression via ErbB2-induced, SUMO-directed phosphorylation of myeloid zinc finger-1 serine 27 activates lysosome redistribution and invasion. Oncogene 38 (17) (2019)
Svetlana Vakkilainen, Tiina Skoog, Elisabet Einarsdottir, Anna Middleton, Minna Pekkinen, Tiina Öhman, Shintaro Katayama, Kaarel Krjutškov, Panu E Kovanen, Markku Varjosalo, Arne Lindqvist, Juha Kere, Outi Mäkitie
The human long non-coding RNA gene RMRP has pleiotropic effects and regulates cell-cycle progression at G2. Scientific reports 9 (1) (2019)
Xiaonan Liu, Kari Salokas, Fitsum Tamene, Yaming Jiu, Rigbe G Weldatsadik, Tiina Öhman, Markku Varjosalo
An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations. Nature communications 9 (1) (2018)
Tiina J Öhman, Fitsum Tamene, Helka Göös, Sirpa Loukovaara, Markku Varjosalo
Systems pathology analysis identifies neurodegenerative nature of age-related vitreoretinal interface diseases. Aging cell 17 (5) (2018)