Michael B Lazarus (Michael Lazarus)

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 26

Top Venues

ACS chemical biology

Research square

bioRxiv : the preprint server for biology

Journal of the American Chemical Society

Icahn School of Medicine at Mount Sinai

Harvard University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Icahn School of Medicine at Mount Sinai Apr 01 2016

United States

Assistant Professor :: Department of Pharmacological Sciences

Education History

Harvard University Sep 01 2004 - May 27 2010

United States

PHD :: Chemistry and Chemical Biology

Publications

Susmita Khamrui, Tetyana Dodatko, Ruoxi Wu, João Leandro, Amanda Sabovic, Sara Violante, Justin R Cross, Eric Marsan, Kunal Kumar, Robert J DeVita, Michael B Lazarus, Sander M Houten
Characterization, structure and inhibition of the human succinyl-CoA:glutarate-CoA transferase, a genetic modifier of glutaric aciduria type 1. bioRxiv : the preprint server for biology (2024)
Susmita Khamrui, Tetyana Dodatko, Ruoxi Wu, João Leandro, Amanda Sabovic, Sara Violante, Justin R Cross, Eric Marsan, Kunal Kumar, Robert J DeVita, Michael B Lazarus, Sander M Houten
Characterization, structure and inhibition of the human succinyl-CoA:glutarate-CoA transferase, a genetic modifier of glutaric aciduria type 1. bioRxiv : the preprint server for biology (2024)
Ruoxi Wu, Susmita Khamrui, Tetyana Dodatko, João Leandro, Amanda Sabovic, Sara Violante, Justin R Cross, Eric Marsan, Kunal Kumar, Robert J DeVita, Michael B Lazarus, Sander M Houten
Characterization, Structure, and Inhibition of the Human Succinyl-CoA:glutarate-CoA Transferase, a Putative Genetic Modifier of Glutaric Aciduria Type 1. ACS chemical biology 19 (7) (2024)
Ruoxi Wu, Shakti Ingle, Sarah A Barnes, Heather R Dahlin, Susmita Khamrui, Yufei Xiang, Yi Shi, David H Bechhofer, Michael B Lazarus
Structural insights into RNA cleavage by a novel family of bacterial RNases. Nucleic acids research (2024)
Susmita Khamrui, Tetyana Dodatko, Ruoxi Wu, João Leandro, Amanda Sabovic, Sara Violante, Justin R Cross, Eric Marsan, Kunal Kumar, Robert J DeVita, Michael B Lazarus, Sander M Houten
Characterization, structure and inhibition of the human succinyl-CoA:glutarate-CoA transferase, a genetic modifier of glutaric aciduria type 1. bioRxiv : the preprint server for biology (2024)
Ruoxi Wu, Susmita Khamrui, Tetyana Dodatko, João Leandro, Amanda Sabovic, Sara Violante, Justin R Cross, Eric Marsan, Kunal Kumar, Robert J DeVita, Michael B Lazarus, Sander M Houten
Characterization, Structure, and Inhibition of the Human Succinyl-CoA:glutarate-CoA Transferase, a Putative Genetic Modifier of Glutaric Aciduria Type 1. ACS chemical biology (2024)
Ruoxi Wu, Susmita Khamrui, Tetyana Dodatko, João Leandro, Amanda Sabovic, Sara Violante, Justin R Cross, Eric Marsan, Kunal Kumar, Robert J DeVita, Michael B Lazarus, Sander M Houten
Characterization, Structure, and Inhibition of the Human Succinyl-CoA:glutarate-CoA Transferase, a Putative Genetic Modifier of Glutaric Aciduria Type 1. ACS chemical biology (2024)
Susmita Khamrui, Tetyana Dodatko, Ruoxi Wu, João Leandro, Amanda Sabovic, Sara Violante, Justin R Cross, Eric Marsan, Kunal Kumar, Robert J DeVita, Michael B Lazarus, Sander M Houten
Characterization, structure and inhibition of the human succinyl-CoA:glutarate-CoA transferase, a genetic modifier of glutaric aciduria type 1. bioRxiv : the preprint server for biology (2024)
Ruoxi Wu, Susmita Khamrui, Tetyana Dodatko, João Leandro, Amanda Sabovic, Sara Violante, Justin R Cross, Eric Marsan, Kunal Kumar, Robert J DeVita, Michael B Lazarus, Sander M Houten
Characterization, Structure, and Inhibition of the Human Succinyl-CoA:glutarate-CoA Transferase, a Putative Genetic Modifier of Glutaric Aciduria Type 1. ACS chemical biology (2024)
Susmita Khamrui, Tetyana Dodatko, Ruoxi Wu, João Leandro, Amanda Sabovic, Sara Violante, Justin R Cross, Eric Marsan, Kunal Kumar, Robert J DeVita, Michael B Lazarus, Sander M Houten
Characterization, structure and inhibition of the human succinyl-CoA:glutarate-CoA transferase, a genetic modifier of glutaric aciduria type 1. bioRxiv : the preprint server for biology (2024)
Ruoxi Wu, Shakti Ingle, Sarah A Barnes, Heather R Dahlin, Susmita Khamrui, Yufei Xiang, Yi Shi, David H Bechhofer, Michael B Lazarus
Structural insights into RNA cleavage by a novel family of bacterial RNases. Nucleic acids research (2024)
Ruoxi Wu, Susmita Khamrui, Tetyana Dodatko, João Leandro, Amanda Sabovic, Sara Violante, Justin R Cross, Eric Marsan, Kunal Kumar, Robert J DeVita, Michael B Lazarus, Sander M Houten
Characterization, Structure, and Inhibition of the Human Succinyl-CoA:glutarate-CoA Transferase, a Putative Genetic Modifier of Glutaric Aciduria Type 1. ACS chemical biology 19 (7) (2024)
Ruoxi Wu, Sarah Barnes, Heather Dahlin, Susmita Khamrui, Shakti Ingle, Yufei Xiang, Yi Shi, David Bechhofer, Michael B Lazarus
Structural insights into RNA cleavage by a novel family of bacterial RNases. Research square (2023)
Ruoxi Wu, Sarah Barnes, Heather Dahlin, Susmita Khamrui, Shakti Ingle, Yufei Xiang, Yi Shi, David Bechhofer, Michael B Lazarus
Structural insights into RNA cleavage by a novel family of bacterial RNases. Research square (2023)
Ruoxi Wu, Sarah Barnes, Heather Dahlin, Susmita Khamrui, Shakti Ingle, Yufei Xiang, Yi Shi, David Bechhofer, Michael B Lazarus
Structural insights into RNA cleavage by a novel family of bacterial RNases. Research square (2023)
Ruoxi Wu, Sarah Barnes, Heather Dahlin, Susmita Khamrui, Shakti Ingle, Yufei Xiang, Yi Shi, David Bechhofer, Michael B Lazarus
Structural insights into RNA cleavage by a novel family of bacterial RNases. Research square (2023)
Ruoxi Wu, Sarah Barnes, Heather Dahlin, Susmita Khamrui, Shakti Ingle, Yufei Xiang, Yi Shi, David Bechhofer, Michael B Lazarus
Structural insights into RNA cleavage by a novel family of bacterial RNases. Research square (2023)
João Leandro, Susmita Khamrui, Chalada Suebsuwong, Peng-Jen Chen, Cody Secor, Tetyana Dodatko, Chunli Yu, Roberto Sanchez, Robert J DeVita, Sander M Houten, Michael B Lazarus
Characterization and structure of the human lysine-2-oxoglutarate reductase domain, a novel therapeutic target for treatment of glutaric aciduria type 1. Open biology 12 (9) (2022)
Kisa Sung, Agata Kurowski, Carisse Lansiquot, Kanny K Wan, Samarjit Patnaik, Martin J Walsh, Michael B Lazarus
Selective Inhibitors of Autophagy Reveal New Link between the Cell Cycle and Autophagy and Lead to Discovery of Novel Synergistic Drug Combinations. ACS chemical biology (2022)
Vadim Baidin, Tristan W Owens, Michael B Lazarus, Daniel E Kahne
Simple Secondary Amines Inhibit Growth of Gram-Negative Bacteria through Highly Selective Binding to Phenylalanyl-tRNA Synthetase. Journal of the American Chemical Society 143 (2) (2021)
Kunal Kumar, Peng Wang, Ethan A Swartz, Susmita Khamrui, Cody Secor, Michael B Lazarus, Roberto Sanchez, Andrew F Stewart, Robert J DeVita
Structure-Activity Relationships and Biological Evaluation of 7-Substituted Harmine Analogs for Human β-Cell Proliferation. Molecules (Basel, Switzerland) 25 (8) (2020)
Xu Zhang, Natalia S Nemeria, João Leandro, Sander M Houten, Michael B Lazarus, Gary Gerfen, Oliver Ozohanics, Attila Ambrus, Balint Nagy, Roman Brukh, Frank Jordan
Structure-function analyses of the G729R 2-oxoadipate dehydrogenase genetic variant associated with a disorder of l-lysine metabolism. The Journal of biological chemistry 295 (23) (2020)
João Leandro, Susmita Khamrui, Hui Wang, Chalada Suebsuwong, Natalia S Nemeria, Khoi Huynh, Moses Moustakim, Cody Secor, May Wang, Tetyana Dodatko, Brandon Stauffer, Christopher G Wilson, Chunli Yu, Michelle R Arkin, Frank Jordan, Roberto Sanchez, Robert J DeVita, Michael B Lazarus, Sander M Houten
Inhibition and Crystal Structure of the Human DHTKD1-Thiamin Diphosphate Complex. ACS chemical biology 15 (8) (2020)
Kunal Kumar, Peng Wang, Jessica Wilson, Viktor Zlatanic, Cecilia Berrouet, Susmita Khamrui, Cody Secor, Ethan A Swartz, Michael B Lazarus, Roberto Sanchez, Andrew F Stewart, Adolfo Garcia-Ocana, Robert J DeVita
Synthesis and Biological Validation of a Harmine-Based, Central Nervous System (CNS)-Avoidant, Selective, Human β-Cell Regenerative Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase A (DYRK1A) Inhibitor. Journal of medicinal chemistry 63 (6) (2020)
Susmita Khamrui, Peter M U Ung, Cody Secor, Avner Schlessinger, Michael B Lazarus
High-Resolution Structure and Inhibition of the Schizophrenia-Linked Pseudokinase ULK4. Journal of the American Chemical Society 142 (1) (2019)
Sara E S Martin, Zhi-Wei Tan, Harri M Itkonen, Damien Y Duveau, Joao A Paulo, John Janetzko, Paul L Boutz, Lisa Törk, Frederick A Moss, Craig J Thomas, Steven P Gygi, Michael B Lazarus, Suzanne Walker
Structure-Based Evolution of Low Nanomolar O-GlcNAc Transferase Inhibitors. Journal of the American Chemical Society 140 (42) (2018)

Michael B Lazarus.css-eqlu8i{font-size:small;padding-left:4px;} (Michael Lazarus)

Publication Activity (10 Years)

Top Topics

Top Venues

Michael B Lazarus (Michael Lazarus)