David Haselbach

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 24

Top Venues

Nature

Nature communications

Nature structural & molecular biology

eLife

Research Institute of Molecular Pathology

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Research Institute of Molecular Pathology Sep 01 2017

Austria

Fellow

Publications

Lisa Kofler, Lorenz Grundmann, Magdalena Gerhalter, Michael Prattes, Juliane Merl-Pham, Gertrude Zisser, Irina Grishkovskaya, Victor-Valentin Hodirnau, Martin Vareka, Rolf Breinbauer, Stefanie M Hauck, David Haselbach, Helmut Bergler
The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation. Nature communications 15 (1) (2024)
Arish N Shah, Friederike Leesch, Laura Lorenzo-Orts, Lorenz Grundmann, Maria Novatchkova, David Haselbach, Eliezer Calo, Andrea Pauli
A dual ribosomal system in the zebrafish soma and germline. bioRxiv : the preprint server for biology (2024)
Friederike Leesch, Laura Lorenzo-Orts, Carina Pribitzer, Irina Grishkovskaya, Josef Roehsner, Anastasia Chugunova, Manuel Matzinger, Elisabeth Roitinger, Katarina Belačić, Susanne Kandolf, Tzi-Yang Lin, Karl Mechtler, Anton Meinhart, David Haselbach, Andrea Pauli
A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature (2023)
Friederike Leesch, Laura Lorenzo-Orts, Carina Pribitzer, Irina Grishkovskaya, Josef Roehsner, Anastasia Chugunova, Manuel Matzinger, Elisabeth Roitinger, Katarina Belačić, Susanne Kandolf, Tzi-Yang Lin, Karl Mechtler, Anton Meinhart, David Haselbach, Andrea Pauli
A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature 613 (7945) (2023)
Friederike Leesch, Laura Lorenzo-Orts, Carina Pribitzer, Irina Grishkovskaya, Josef Roehsner, Anastasia Chugunova, Manuel Matzinger, Elisabeth Roitinger, Katarina Belačić, Susanne Kandolf, Tzi-Yang Lin, Karl Mechtler, Anton Meinhart, David Haselbach, Andrea Pauli
A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature 613 (7945) (2023)
Friederike Leesch, Laura Lorenzo-Orts, Carina Pribitzer, Irina Grishkovskaya, Josef Roehsner, Anastasia Chugunova, Manuel Matzinger, Elisabeth Roitinger, Katarina Belačić, Susanne Kandolf, Tzi-Yang Lin, Karl Mechtler, Anton Meinhart, David Haselbach, Andrea Pauli
A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature 613 (7945) (2023)
Friederike Leesch, Laura Lorenzo-Orts, Carina Pribitzer, Irina Grishkovskaya, Josef Roehsner, Anastasia Chugunova, Manuel Matzinger, Elisabeth Roitinger, Katarina Belačić, Susanne Kandolf, Tzi-Yang Lin, Karl Mechtler, Anton Meinhart, David Haselbach, Andrea Pauli
A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature 613 (7945) (2023)
Friederike Leesch, Laura Lorenzo-Orts, Carina Pribitzer, Irina Grishkovskaya, Josef Roehsner, Anastasia Chugunova, Manuel Matzinger, Elisabeth Roitinger, Katarina Belačić, Susanne Kandolf, Tzi-Yang Lin, Karl Mechtler, Anton Meinhart, David Haselbach, Andrea Pauli
A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature 613 (7945) (2023)
Friederike Leesch, Laura Lorenzo-Orts, Carina Pribitzer, Irina Grishkovskaya, Josef Roehsner, Anastasia Chugunova, Manuel Matzinger, Elisabeth Roitinger, Katarina Belačić, Susanne Kandolf, Tzi-Yang Lin, Karl Mechtler, Anton Meinhart, David Haselbach, Andrea Pauli
A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature 613 (7945) (2023)
Friederike Leesch, Laura Lorenzo-Orts, Carina Pribitzer, Irina Grishkovskaya, Josef Roehsner, Anastasia Chugunova, Manuel Matzinger, Elisabeth Roitinger, Katarina Belačić, Susanne Kandolf, Tzi-Yang Lin, Karl Mechtler, Anton Meinhart, David Haselbach, Andrea Pauli
A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature 613 (7945) (2023)
Friederike Leesch, Laura Lorenzo-Orts, Carina Pribitzer, Irina Grishkovskaya, Josef Roehsner, Anastasia Chugunova, Manuel Matzinger, Elisabeth Roitinger, Katarina Belačić, Susanne Kandolf, Tzi-Yang Lin, Karl Mechtler, Anton Meinhart, David Haselbach, Andrea Pauli
A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature 613 (7945) (2023)
Zuzana Hodáková, Irina Grishkovskaya, Hanna L Brunner, Derek L Bolhuis, Katarina Belačić, Alexander Schleiffer, Harald Kotisch, Nicholas G Brown, David Haselbach
Cryo-EM structure of the chain-elongating E3 ubiquitin ligase UBR5. The EMBO journal (2023)
Tatyana Bodrug, Kaeli A Welsh, Derek L Bolhuis, Ethan Paulаkonis, Raquel C Martinez-Chacin, Bei Liu, Nicholas Pinkin, Thomas Bonacci, Liying Cui, Pengning Xu, Olivia Roscow, Sascha Josef Amann, Irina Grishkovskaya, Michael J Emanuele, Joseph S Harrison, Joshua P Steimel, Klaus M Hahn, Wei Zhang, Ellen D Zhong, David Haselbach, Nicholas G Brown
Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C). Nature structural & molecular biology (2023)
Friederike Leesch, Laura Lorenzo-Orts, Carina Pribitzer, Irina Grishkovskaya, Josef Roehsner, Anastasia Chugunova, Manuel Matzinger, Elisabeth Roitinger, Katarina Belačić, Susanne Kandolf, Tzi-Yang Lin, Karl Mechtler, Anton Meinhart, David Haselbach, Andrea Pauli
A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature 613 (7945) (2023)
Catarina Pechincha, Sven Groessl, Robert Kalis, Melanie de Almeida, Andrea Zanotti, Marten Wittmann, Martin Schneider, Rafael Paschoal de Campos, Sarah Rieser, Marlene Brandstetter, Alexander Schleiffer, Karin Müller-Decker, Dominic Helm, Sabrina Jabs, David Haselbach, Marius K Lemberg, Johannes Zuber, Wilhelm Palm
Lysosomal enzyme trafficking factor LYSET enables nutritional usage of extracellular proteins. Science (New York, N.Y.) 378 (6615) (2022)
Michael Prattes, Irina Grishkovskaya, Victor-Valentin Hodirnau, Christina Hetzmannseder, Gertrude Zisser, Carolin Sailer, Vasileios Kargas, Mathias Loibl, Magdalena Gerhalter, Lisa Kofler, Alan John Warren, Florian Stengel, David Haselbach, Helmut Bergler
Visualizing maturation factor extraction from the nascent ribosome by the AAA-ATPase Drg1. Nature structural & molecular biology 29 (9) (2022)
Melanie de Almeida, Matthias Hinterndorfer, Hanna Brunner, Irina Grishkovskaya, Kashish Singh, Alexander Schleiffer, Julian Jude, Sumit Deswal, Robert Kalis, Milica Vunjak, Thomas Lendl, Richard Imre, Elisabeth Roitinger, Tobias Neumann, Susanne Kandolf, Michael Schutzbier, Karl Mechtler, Gijs A Versteeg, David Haselbach, Johannes Zuber
AKIRIN2 controls the nuclear import of proteasomes in vertebrates. Nature 599 (7885) (2021)
Michael Prattes, Irina Grishkovskaya, Victor-Valentin Hodirnau, Ingrid Rössler, Isabella Klein, Christina Hetzmannseder, Gertrude Zisser, Christian C Gruber, Karl Gruber, David Haselbach, Helmut Bergler
Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine. Nature communications 12 (1) (2021)
Paula Gutiérrez-Pérez, Emilio M Santillán, Thomas Lendl, Jingkui Wang, Anna Schrempf, Thomas L Steinacker, Mila Asparuhova, Marlene Brandstetter, David Haselbach, Luisa Cochella
miR-1 sustains muscle physiology by controlling V-ATPase complex assembly. Science advances 7 (42) (2021)
Daniel B Grabarczyk, Olga A Petrova, Luiza Deszcz, Robert Kurzbauer, Paul Murphy, Juraj Ahel, Antonia Vogel, Rebeca Gogova, Victoria Faas, Darja Kordic, Alexander Schleiffer, Anton Meinhart, Richard Imre, Anita Lehner, Jana Neuhold, Gerd Bader, Peggy Stolt-Bergner, Jark Böttcher, Bernhard Wolkerstorfer, Gerhard Fischer, Irina Grishkovskaya, David Haselbach, Dirk Kessler, Tim Clausen
HUWE1 employs a giant substrate-binding ring to feed and regulate its HECT E3 domain. Nature chemical biology 17 (10) (2021)
Alan Rodriguez Carvajal, Irina Grishkovskaya, Carlos Gomez-Diaz, Antonia Vogel, Adar Sonn-Segev, Manish S Kushwah, Katrin Schodl, Luiza Deszcz, Zsuzsanna Orban-Nemeth, Shinji Sakamoto, Karl Mechtler, Philipp Kukura, Tim Clausen, David Haselbach, Fumiyo Ikeda
The linear ubiquitin chain assembly complex (LUBAC) generates heterotypic ubiquitin chains. eLife 10 (2021)
Adar Sonn-Segev, Katarina Belačić, Tatyana Bodrug, Gavin Young, Ryan T VanderLinden, Brenda A Schulman, Johannes Schimpf, Thorsten Friedrich, Phat Vinh Dip, Thomas U Schwartz, Benedikt Bauer, Jan-Michael Peters, Weston B Struwe, Justin L P Benesch, Nicholas G Brown, David Haselbach, Philipp Kukura
Quantifying the heterogeneity of macromolecular machines by mass photometry. Nature communications 11 (1) (2020)
Juraj Ahel, Anita Lehner, Antonia Vogel, Alexander Schleiffer, Anton Meinhart, David Haselbach, Tim Clausen
Moyamoya disease factor RNF213 is a giant E3 ligase with a dynein-like core and a distinct ubiquitin-transfer mechanism. eLife 9 (2020)
David Haselbach, Jil Schrader, Felix Lambrecht, Fabian Henneberg, Ashwin Chari, Holger Stark
Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs. Nature communications 8 (2017)
Ashwin Chari, David Haselbach, Jan-Martin Kirves, Juergen Ohmer, Elham Paknia, Niels Fischer, Oleg Ganichkin, Vanessa Möller, Jeremiah J Frye, Georg Petzold, Marc Jarvis, Michael Tietzel, Clemens Grimm, Jan-Michael Peters, Brenda A Schulman, Kai Tittmann, Jürgen Markl, Utz Fischer, Holger Stark
ProteoPlex: stability optimization of macromolecular complexes by sparse-matrix screening of chemical space. Nature methods 12 (9) (2015)

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Publication Activity (10 Years)

Top Topics

Top Venues

David Haselbach