Michael Nassal

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 24

Top Venues

Nature communications

PLoS pathogens

Proceedings of the National Academy of Sciences of the United States of America

Microbiology spectrum

University Hospital Freiburg

University of Heidelberg (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University Hospital Freiburg May 05 1997

Germany

Professor of Medical Molecular Biology :: Internal Medicine 2 / Molecular Biology

University of Heidelberg Apr 01 1989 - May 04 1997

Germany

University Assistant and Project Group Leader :: Microbiology and Center for Molecular Biology Heidelberg (ZMBH)

University of Heidelberg Jan 16 1986 - Mar 31 1989

Germany

Research Assistant and Head Oligonucleotide Synthesis :: Center for Molecular Biology Heidelberg (ZMBH)

Massachusetts Institute of Technology Sep 01 1983 - Jan 15 1986

United States

post-doc :: Biology & Chemistry

Max Planck Institute for Medical Research Oct 01 1980 - Aug 31 1983

Germany

Research Assistant :: Natural Products Chemistry

Education History

University of Heidelberg

Germany

PHD :: Faculty of Chemistry

Publications

Samuel Hofmann, Julius Luther, Verena Plank, Andreas Oswald, Julia Mai, Ilka Simons, Julija Miller, Valeria Falcone, Lea Hansen-Palmus, Hartmut Hengel, Michael Nassal, Ulrike Protzer, Sabrina Schreiner
Arsenic trioxide impacts hepatitis B virus core nuclear localization and efficiently interferes with HBV infection. Microbiology spectrum (2024)
Sara Pfister, Julius Rabl, Thomas Wiegand, Simone Mattei, Alexander A Malär, Lauriane Lecoq, Stefan Seitz, Ralf F W Bartenschlager, Anja Böckmann, Michael Nassal, Daniel Boehringer, Beat H Meier
Structural conservation of HBV-like capsid proteins over hundreds of millions of years despite the shift from non-enveloped to enveloped life-style. Nature communications 14 (1) (2023)
Sara Pfister, Julius Rabl, Thomas Wiegand, Simone Mattei, Alexander A Malär, Lauriane Lecoq, Stefan Seitz, Ralf F W Bartenschlager, Anja Böckmann, Michael Nassal, Daniel Boehringer, Beat H Meier
Structural conservation of HBV-like capsid proteins over hundreds of millions of years despite the shift from non-enveloped to enveloped life-style. Nature communications 14 (1) (2023)
Samuel Hofmann, Verena Plank, Peter Groitl, Nathalie Skvorc, Katharina Hofmann, Julius Luther, Chunkyu Ko, Peter Zimmerman, Volker Bruss, Daniela Stadler, Arnaud Carpentier, Shahinda Rezk, Michael Nassal, Ulrike Protzer, Sabrina Schreiner
SUMO Modification of Hepatitis B Virus Core Mediates Nuclear Entry, Promyelocytic Leukemia Nuclear Body Association, and Efficient Formation of Covalently Closed Circular DNA. Microbiology spectrum (2023)
Lauriane Lecoq, Louis Brigandat, Rebecca Huber, Marie-Laure Fogeron, Shishan Wang, Marie Dujardin, Mathilde Briday, Thomas Wiegand, Morgane Callon, Alexander Malär, David Durantel, Dara Burdette, Jan Martin Berke, Beat H Meier, Michael Nassal, Anja Böckmann
Molecular elucidation of drug-induced abnormal assemblies of the hepatitis B virus capsid protein by solid-state NMR. Nature communications 14 (1) (2023)
Sara Pfister, Julius Rabl, Thomas Wiegand, Simone Mattei, Alexander A Malär, Lauriane Lecoq, Stefan Seitz, Ralf F W Bartenschlager, Anja Böckmann, Michael Nassal, Daniel Boehringer, Beat H Meier
Structural conservation of HBV-like capsid proteins over hundreds of millions of years despite the shift from non-enveloped to enveloped life-style. Nature communications 14 (1) (2023)
Lauriane Lecoq, Louis Brigandat, Rebecca Huber, Marie-Laure Fogeron, Shishan Wang, Marie Dujardin, Mathilde Briday, Thomas Wiegand, Morgane Callon, Alexander Malär, David Durantel, Dara Burdette, Jan Martin Berke, Beat H Meier, Michael Nassal, Anja Böckmann
Molecular elucidation of drug-induced abnormal assemblies of the hepatitis B virus capsid protein by solid-state NMR. Nature communications 14 (1) (2023)
Lauriane Lecoq, Louis Brigandat, Rebecca Huber, Marie-Laure Fogeron, Shishan Wang, Marie Dujardin, Mathilde Briday, Thomas Wiegand, Morgane Callon, Alexander Malär, David Durantel, Dara Burdette, Jan Martin Berke, Beat H Meier, Michael Nassal, Anja Böckmann
Molecular elucidation of drug-induced abnormal assemblies of the hepatitis B virus capsid protein by solid-state NMR. Nature communications 14 (1) (2023)
Lauriane Lecoq, Louis Brigandat, Rebecca Huber, Marie-Laure Fogeron, Shishan Wang, Marie Dujardin, Mathilde Briday, Thomas Wiegand, Morgane Callon, Alexander Malär, David Durantel, Dara Burdette, Jan Martin Berke, Beat H Meier, Michael Nassal, Anja Böckmann
Molecular elucidation of drug-induced abnormal assemblies of the hepatitis B virus capsid protein by solid-state NMR. Nature communications 14 (1) (2023)
Katharina Dörnbrack, Jürgen Beck, Michael Nassal
Relaxing the restricted structural dynamics in the human hepatitis B virus RNA encapsidation signal enables replication initiation in vitro. PLoS pathogens 18 (3) (2022)
Mathilde Briday, François Hallé, Lauriane Lecoq, Sylvie Radix, Juliette Martin, Roland Montserret, Marie Dujardin, Marie-Laure Fogeron, Michael Nassal, Beat H Meier, Thierry Lomberget, Anja Böckmann
Pharmacomodulation of a ligand targeting the HBV capsid hydrophobic pocket. Chemical science 13 (30) (2022)
Michael Nassal
How many steps to a feasible mouse model of hepatitis B virus infection? Hepatology (Baltimore, Md.) (2022)
Yang Wang, Wenjie Yuan, Siqi Guo, Qiqi Li, Xiaomei Chen, Cheng Li, Qianying Liu, Lei Sun, Zhenguo Chen, Zhenghong Yuan, Cheng Luo, Shijie Chen, Shuping Tong, Michael Nassal, Yu-Mei Wen, Yong-Xiang Wang
A 33-residue peptide tag increases solubility and stability of Escherichia coli produced single-chain antibody fragments. Nature communications 13 (1) (2022)
Eloi R Verrier, Gaetan Ligat, Laura Heydmann, Katharina Doernbrack, Julija Miller, Anne Maglott-Roth, Frank Jühling, Houssein El Saghire, Margaux J Heuschkel, Naoto Fujiwara, Sen-Yung Hsieh, Yujin Hoshida, David E Root, Emanuele Felli, Patrick Pessaux, Atish Mukherji, Laurent Mailly, Catherine Schuster, Laurent Brino, Michael Nassal, Thomas F Baumert
Cell-based cccDNA reporter assay combined with functional genomics identifies YBX1 as HBV cccDNA host factor and antiviral candidate target. Gut (2022)
Morgane Callon, Alexander A Malär, Lauriane Lecoq, Marie Dujardin, Marie-Laure Fogeron, Shishan Wang, Maarten Schledorn, Thomas Bauer, Michael Nassal, Anja Böckmann, Beat H Meier
Fast Magic-Angle-Spinning NMR Reveals the Evasive Hepatitis B Virus Capsid C-Terminal Domain. Angewandte Chemie (International ed. in English) 61 (32) (2022)
Jürgen Beck, Stefan Seitz, Chris Lauber, Michael Nassal
Conservation of the HBV RNA element epsilon in nackednaviruses reveals ancient origin of protein-primed reverse transcription. Proceedings of the National Academy of Sciences of the United States of America 118 (13) (2021)
Lauriane Lecoq, Shishan Wang, Marie Dujardin, Peter Zimmermann, Leonard Schuster, Marie-Laure Fogeron, Mathilde Briday, Maarten Schledorn, Thomas Wiegand, Laura Cole, Roland Montserret, Stéphane Bressanelli, Beat H Meier, Michael Nassal, Anja Böckmann
A pocket-factor-triggered conformational switch in the hepatitis B virus capsid. Proceedings of the National Academy of Sciences of the United States of America 118 (17) (2021)
Matthias Niklasch, Peter Zimmermann, Michael Nassal
The Hepatitis B Virus Nucleocapsid-Dynamic Compartment for Infectious Virus Production and New Antiviral Target. Biomedicines 9 (11) (2021)
Cihan Makbul, Michael Nassal, Bettina Boettcher
Slowly folding surface extension in the prototypic avian hepatitis B virus capsid governs stability. eLife 9 (2020)
Lauriane Lecoq, Marie-Laure Fogeron, Beat H Meier, Michael Nassal, Anja Böckmann
Solid-State NMR for Studying the Structure and Dynamics of Viral Assemblies. Viruses 12 (10) (2020)
Carla Eller, Laura Heydmann, Che C Colpitts, Houssein El Saghire, Frederica Piccioni, Frank Jühling, Karim Majzoub, Caroline Pons, Charlotte Bach, Julie Lucifora, Joachim Lupberger, Michael Nassal, Glenn S Cowley, Naoto Fujiwara, Sen-Yung Hsieh, Yujin Hoshida, Emanuele Felli, Patrick Pessaux, Camille Sureau, Catherine Schuster, David E Root, Thomas F Baumert, Thomas F Baumert
A genome-wide gain-of-function screen identifies CDKN2C as a HBV host factor. Nature communications 11 (1) (2020)
Julia Heger-Stevic, Peter Zimmermann, Lauriane Lecoq, Bettina Boettcher, Michael Nassal
Hepatitis B virus core protein phosphorylation: Identification of the SRPK1 target sites and impact of their occupancy on RNA binding and capsid structure. PLoS pathogens 14 (12) (2018)
Lauriane Lecoq, Shishan Wang, Thomas Wiegand, Stéphane Bressanelli, Michael Nassal, Beat H Meier, Anja Böckmann
Localizing Conformational Hinges by NMR: Where Do Hepatitis B Virus Core Proteins Adapt for Capsid Assembly? Chemphyschem : a European journal of chemical physics and physical chemistry 19 (11) (2018)
Guillaume David, Marie-Laure Fogeron, Maarten Schledorn, Roland Montserret, Uta Haselmann, Susanne Penzel, Aurélie Badillo, Lauriane Lecoq, Patrice Andre, Michael Nassal, Ralf F W Bartenschlager, Beat H Meier, Anja Böckmann
Structural Studies of Self-Assembled Subviral Particles: Combining Cell-Free Expression with 110 kHz MAS NMR Spectroscopy. Angewandte Chemie (International ed. in English) 57 (17) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Michael Nassal