Frederica Piccioni (F Piccioni, Federica Piccioni)

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 29

Top Venues

Nature communications

Cancer discovery

Acta neuropathologica communications

Molecular cancer research : MCR

Broad Institute

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Broad Institute Apr 20 2010

United States

Group Leader :: Genetic Perturbation Platform

Publications

Foteini Tsiami, Chiara Lago, Noemi Pozza, Frederica Piccioni, Xuesong Zhao, Fabienne Lülsberg, David E Root, Luca Tiberi, Marcel Kool, Cornelia Brendle, Pratiti Bandopadhayay, Rosalind A Segal, Ghazaleh Tabatabai, Daniel J Merk
Genome-wide CRISPR-Cas9 knockout screens identify DNMT1 as a druggable dependency in sonic hedgehog medulloblastoma. Acta neuropathologica communications 12 (1) (2024)
Tikvah K Hayes, Elisa Aquilanti, Nicole S Persky, Xiaoping Yang, Erica E Kim, Lisa Brenan, Amy B Goodale, Douglas Alan, Ted Sharpe, Robert E Shue, Lindsay Westlake, Lior Golomb, Brianna R Silverman, Myshal D Morris, Ty Running Fisher, Eden Beyene, Yvonne Y Li, Andrew D Cherniak, Frederica Piccioni, J Kevin Hicks, Andrew S Chi, Daniel P Cahill, Jorg Dietrich, Tracy T Batchelor, David E Root, Cory M Johannessen, Matthew L Meyerson
Comprehensive mutational scanning of EGFR reveals TKI sensitivities of extracellular domain mutants. Nature communications 15 (1) (2024)
Tikvah K Hayes, Elisa Aquilanti, Nicole S Persky, Xiaoping Yang, Erica E Kim, Lisa Brenan, Amy B Goodale, Douglas Alan, Ted Sharpe, Robert E Shue, Lindsay Westlake, Lior Golomb, Brianna R Silverman, Myshal D Morris, Ty Running Fisher, Eden Beyene, Yvonne Y Li, Andrew D Cherniak, Frederica Piccioni, J Kevin Hicks, Andrew S Chi, Daniel P Cahill, Jorg Dietrich, Tracy T Batchelor, David E Root, Cory M Johannessen, Matthew L Meyerson
Comprehensive mutational scanning of EGFR reveals TKI sensitivities of extracellular domain mutants. Nature communications 15 (1) (2024)
Foteini Tsiami, Chiara Lago, Noemi Pozza, Frederica Piccioni, Xuesong Zhao, Fabienne Lülsberg, David E Root, Luca Tiberi, Marcel Kool, Cornelia Brendle, Pratiti Bandopadhayay, Rosalind A Segal, Ghazaleh Tabatabai, Daniel J Merk
Genome-wide CRISPR-Cas9 knockout screens identify DNMT1 as a druggable dependency in sonic hedgehog medulloblastoma. Acta neuropathologica communications 12 (1) (2024)
Tikvah K Hayes, Elisa Aquilanti, Nicole S Persky, Xiaoping Yang, Erica E Kim, Lisa Brenan, Amy B Goodale, Douglas Alan, Ted Sharpe, Robert E Shue, Lindsay Westlake, Lior Golomb, Brianna R Silverman, Myshal D Morris, Ty Running Fisher, Eden Beyene, Yvonne Y Li, Andrew D Cherniak, Frederica Piccioni, J Kevin Hicks, Andrew S Chi, Daniel P Cahill, Jorg Dietrich, Tracy T Batchelor, David E Root, Cory M Johannessen, Matthew L Meyerson
Comprehensive mutational scanning of EGFR reveals TKI sensitivities of extracellular domain mutants. Nature communications 15 (1) (2024)
Foteini Tsiami, Chiara Lago, Noemi Pozza, Frederica Piccioni, Xuesong Zhao, Fabienne Lülsberg, David E Root, Luca Tiberi, Marcel Kool, Cornelia Brendle, Pratiti Bandopadhayay, Rosalind A Segal, Ghazaleh Tabatabai, Daniel J Merk
Genome-wide CRISPR-Cas9 knockout screens identify DNMT1 as a druggable dependency in sonic hedgehog medulloblastoma. Acta neuropathologica communications 12 (1) (2024)
Tikvah K Hayes, Elisa Aquilanti, Nicole S Persky, Xiaoping Yang, Erica E Kim, Lisa Brenan, Amy B Goodale, Douglas Alan, Ted Sharpe, Robert E Shue, Lindsay Westlake, Lior Golomb, Brianna R Silverman, Myshal D Morris, Ty Running Fisher, Eden Beyene, Yvonne Y Li, Andrew D Cherniak, Frederica Piccioni, J Kevin Hicks, Andrew S Chi, Daniel P Cahill, Jorg Dietrich, Tracy T Batchelor, David E Root, Cory M Johannessen, Matthew L Meyerson
Comprehensive mutational scanning of EGFR reveals TKI sensitivities of extracellular domain mutants. Nature communications 15 (1) (2024)
Tikvah K Hayes, Elisa Aquilanti, Nicole S Persky, Xiaoping Yang, Erica E Kim, Lisa Brenan, Amy B Goodale, Douglas Alan, Ted Sharpe, Robert E Shue, Lindsay Westlake, Lior Golomb, Brianna R Silverman, Myshal D Morris, Ty Running Fisher, Eden Beyene, Yvonne Y Li, Andrew D Cherniak, Frederica Piccioni, J Kevin Hicks, Andrew S Chi, Daniel P Cahill, Jorg Dietrich, Tracy T Batchelor, David E Root, Cory M Johannessen, Matthew L Meyerson
Comprehensive mutational scanning of EGFR reveals TKI sensitivities of extracellular domain mutants. Nature communications 15 (1) (2024)
Tikvah K Hayes, Elisa Aquilanti, Nicole S Persky, Xiaoping Yang, Erica E Kim, Lisa Brenan, Amy B Goodale, Douglas Alan, Ted Sharpe, Robert E Shue, Lindsay Westlake, Lior Golomb, Brianna R Silverman, Myshal D Morris, Ty Running Fisher, Eden Beyene, Yvonne Y Li, Andrew D Cherniak, Frederica Piccioni, J Kevin Hicks, Andrew S Chi, Daniel P Cahill, Jorg Dietrich, Tracy T Batchelor, David E Root, Cory M Johannessen, Matthew L Meyerson
Author Correction: Comprehensive mutational scanning of EGFR reveals TKI sensitivities of extracellular domain mutants. Nature communications 15 (1) (2024)
Tikvah K Hayes, Elisa Aquilanti, Nicole S Persky, Xiaoping Yang, Erica E Kim, Lisa Brenan, Amy B Goodale, Douglas Alan, Ted Sharpe, Robert E Shue, Lindsay Westlake, Lior Golomb, Brianna R Silverman, Myshal D Morris, Ty Running Fisher, Eden Beyene, Yvonne Y Li, Andrew D Cherniak, Frederica Piccioni, J Kevin Hicks, Andrew S Chi, Daniel P Cahill, Jorg Dietrich, Tracy T Batchelor, David E Root, Cory M Johannessen, Matthew L Meyerson
Author Correction: Comprehensive mutational scanning of EGFR reveals TKI sensitivities of extracellular domain mutants. Nature communications 15 (1) (2024)
Tikvah K Hayes, Elisa Aquilanti, Nicole S Persky, Xiaoping Yang, Erica E Kim, Lisa Brenan, Amy B Goodale, Douglas Alan, Ted Sharpe, Robert E Shue, Lindsay Westlake, Lior Golomb, Brianna R Silverman, Myshal D Morris, Ty Running Fisher, Eden Beyene, Yvonne Y Li, Andrew D Cherniak, Frederica Piccioni, J Kevin Hicks, Andrew S Chi, Daniel P Cahill, Jorg Dietrich, Tracy T Batchelor, David E Root, Cory M Johannessen, Matthew L Meyerson
Comprehensive mutational scanning of EGFR reveals TKI sensitivities of extracellular domain mutants. Nature communications 15 (1) (2024)
Lisa D Cervia, Tsukasa Shibue, Ashir A Borah, Benjamin Gaeta, Linh He, Lisa Leung, Naomi Li, Sydney M Moyer, Brian H Shim, Nancy Dumont, Alfredo E Gonzalez, Nolan R Bick, Mariya Kazachkova, Joshua M Dempster, John Michael Krill-Burger, Frederica Piccioni, Namrata D Udeshi, Meagan E Olive, Steven A Carr, David E Root, James M McFarland, Francisca Vazquez, William C Hahn
A Ubiquitination Cascade Regulating the Integrated Stress Response and Survival in Carcinomas. Cancer discovery 13 (3) (2023)
Lisa D Cervia, Tsukasa Shibue, Ashir A Borah, Benjamin Gaeta, Linh He, Lisa Leung, Naomi Li, Sydney M Moyer, Brian H Shim, Nancy Dumont, Alfredo E Gonzalez, Nolan R Bick, Mariya Kazachkova, Joshua M Dempster, John Michael Krill-Burger, Frederica Piccioni, Namrata D Udeshi, Meagan E Olive, Steven A Carr, David E Root, James M McFarland, Francisca Vazquez, William C Hahn
A Ubiquitination Cascade Regulating the Integrated Stress Response and Survival in Carcinomas. Cancer discovery 13 (3) (2023)
Lisa D Cervia, Tsukasa Shibue, Ashir A Borah, Benjamin Gaeta, Linh He, Lisa Leung, Naomi Li, Sydney M Moyer, Brian H Shim, Nancy Dumont, Alfredo E Gonzalez, Nolan R Bick, Mariya Kazachkova, Joshua M Dempster, John Michael Krill-Burger, Frederica Piccioni, Namrata D Udeshi, Meagan E Olive, Steven A Carr, David E Root, James M McFarland, Francisca Vazquez, William C Hahn
A Ubiquitination Cascade Regulating the Integrated Stress Response and Survival in Carcinomas. Cancer discovery 13 (3) (2023)
Tanaz Abid, Amy B Goodale, Zohra Kalani, Meghan Wyatt, Elizabeth M Gonzalez, Kevin Ning Zhou, Kenin Qian, Dana Novikov, Alexandra-Larisa Condurat, Pratiti Bandopadhayay, Frederica Piccioni, Nicole S Persky, David E Root
Genome-wide pooled CRISPR screening in neurospheres. Nature protocols (2023)
Prasidda Khadka, Zachary J Reitman, Sophie Lu, Graham Buchan, Gabrielle Gionet, Frank Dubois, Diana M Carvalho, Juliann Shih, Shu Zhang, Noah F Greenwald, Travis Zack, Ofer Shapira, Kristine Pelton, Rachel Hartley, Heather Bear, Yohanna Georgis, Spandana Jarmale, Randy Melanson, Kevin Bonanno, Kathleen Schoolcraft, Peter G Miller, Alexandra L Condurat, Elizabeth M Gonzalez, Kenin Qian, Eric Morin, Jaldeep Langhnoja, Leslie E Lupien, Veronica Rendo, Jeromy Digiacomo, Dayle K Wang, Kevin Ning Zhou, Rushil Kumbhani, Maria E Guerra Garcia, Claire E Sinai, Sarah Becker, Rachel Schneider, Jayne Vogelzang, Karsten Krug, Amy Goodale, Tanaz Abid, Zohra Kalani, Frederica Piccioni, Rameen Beroukhim, Nicole S Persky, David E Root, Angel Montero Carcaboso, Benjamin L Ebert, Christine Fuller, Ozgun Babur, Mark W Kieran, Chris Jones, Hasmik Keshishian, Keith L Ligon, Steven A Carr, Timothy N Phoenix, Pratiti Bandopadhayay
PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation. Nature communications 13 (1) (2022)
Lisa D Cervia, Tsukasa Shibue, Ashir A Borah, Benjamin Gaeta, Linh He, Lisa Leung, Naomi Li, Sydney M Moyer, Brian H Shim, Nancy Dumont, Alfredo E Gonzalez, Nolan R Bick, Mariya Kazachkova, Joshua M Dempster, John Michael Krill-Burger, Frederica Piccioni, Namrata D Udeshi, Meagan E Olive, Steven A Carr, David E Root, James M McFarland, Francisca Vazquez, William C Hahn
A ubiquitination cascade regulating the integrated stress response and survival in carcinomas. Cancer discovery (2022)
Eshini Panditharatna, Joana G Marques, Tingjian Wang, Maria C Trissal, Ilon Liu, Li Jiang, Alexander Beck, Andrew Groves, Neekesh V Dharia, Deyao Li, Samantha E Hoffman, Guillaume Kugener, McKenzie L Shaw, Hafsa M Mire, Olivia A Hack, Joshua M Dempster, Caleb A Lareau, Lingling Dai, Logan H Sigua, Michael A Quezada, Ann-Catherine J Stanton, Meghan Wyatt, Zohra Kalani, Amy Goodale, Francisca Vazquez, Frederica Piccioni, John G Doench, David E Root, Jamie N Anastas, Kristen L Jones, Amy Saur Conway, Sylwia A Stopka, Michael S Regan, Yu Liang, Hyuk-Soo Seo, Kijun Song, Puspalata Bashyal, William P Jerome, Nathan D Mathewson, Sirano Dhe-Paganon, Mario L Suvà, Angel Montero Carcaboso, Cinzia Lavarino, Jaume Catala-Mora, Quang-De Nguyen, Keith L Ligon, Yang Shi, Sameer Agnihotri, Nathalie Y R Agar, Kimberly Stegmaier, Charles D Stiles, Michelle Monje, Todd R Golub, Jun Qi, Mariella G Filbin
BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma. Cancer discovery 12 (12) (2022)
Ator Ashoti, Francesco Limone, Melissa van Kranenburg, Anna Alemany, Mirna Baak, Judith Vivié, Frederica Piccioni, Pascale F Dijkers, Menno Creyghton, Kevin Eggan, Niels Geijsen
Considerations and practical implications of performing a phenotypic CRISPR/Cas survival screen. PloS one 17 (2) (2022)
Clare F Malone, Minjee Kim, Gabriela Alexe, Kathleen L Engel, Alexandra B Forman, Amanda L Robichaud, Amy Saur Conway, Amy Goodale, Ashleigh Meyer, Delan Khalid, Allen Thayakumar, John M Hatcher, Nathanael S Gray, Frederica Piccioni, Kimberly Stegmaier
Transcriptional Antagonism by CDK8 Inhibition Improves Therapeutic Efficacy of MEK Inhibitors. Cancer research (2022)
Shan Lin, Clement Larrue, Nastassja K Scheidegger, Bo Kyung Alex Seong, Neekesh V Dharia, Miljan Kuljanin, Caroline S Wechsler, Guillaume Kugener, Amanda L Robichaud, Amy Saur Conway, Thelma Mashaka, Sarah Mouche, Biniam Adane, Jeremy Adam Ryan, Joseph D Mancias, Scott T Younger, Frederica Piccioni, Lynn H Lee, Mark Wunderlich, Anthony G Letai, Jerome Tamburini, Kimberly Stegmaier
An in vivo CRISPR screening platform for prioritizing therapeutic targets in AML. Cancer discovery (2021)
Jennifer A Calvo, Briana Fritchman, Desiree Hernandez, Nicole S Persky, Cory M Johannessen, Frederica Piccioni, Brian A Kelch, Sharon B Cantor
Comprehensive Mutational Analysis of the BRCA1-Associated DNA Helicase and Tumor-Suppressor FANCJ/BACH1/BRIP1. Molecular cancer research : MCR 19 (6) (2021)
N S Persky, D Hernandez, M Do Carmo, L Brenan, O Cohen, S Kitajima, U Nayar, A Walker, S Pantel, Y Lee, J Cordova, M Sathappa, C Zhu, T K Hayes, P Ram, P Pancholi, T S Mikkelsen, D A Barbie, X Yang, Rizwan Haq, Frederica Piccioni, David E Root, Cory M Johannessen
Defining the landscape of ATP-competitive inhibitor resistance residues in protein kinases. Nature structural & molecular biology 27 (1) (2020)
Pingping Mao, Ofir Cohen, Kailey J Kowalski, Justin G Kusiel, Jorge E Buendia-Buendia, Michael S Cuoco, Pedro Exman, Seth A Wander, Adrienne G Waks, Utthara Nayar, Jon H Chung, Samuel S Freeman, Orit Rozenblatt-Rosen, Vincent A Miller, Frederica Piccioni, David E Root, Aviv Regev, Eric P Winer, Nancy U Lin, Nikhil Wagle
Acquired FGFR and FGF Alterations Confer Resistance to Estrogen Receptor (ER) Targeted Therapy in ER+ Metastatic Breast Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 26 (22) (2020)
Steffen Boettcher, Peter Grant Miller, Rohan Sharma, Marie McConkey, Matthew Joseph Leventhal, Andrei V Krivtsov, Andrew O Giacomelli, Waihay J Wong, Jesi Kim, Sherry Chao, Kari J Kurppa, Xiaoping Yang, Kirsten Milenkowic, Frederica Piccioni, David E Root, Frank G Rücker, Yael Flamand, Donna S Neuberg, R Coleman Lindsley, Pasi A Jänne, William C Hahn, Tyler Jacks, Hartmut Döhner, Scott A Armstrong, Benjamin L Ebert
A dominant-negative effect drives selection of TP53 missense mutations in myeloid malignancies. Science (New York, N.Y.) 365 (6453) (2020)
Carla Eller, Laura Heydmann, Che C Colpitts, Houssein El Saghire, Frederica Piccioni, Frank Jühling, Karim Majzoub, Caroline Pons, Charlotte Bach, Julie Lucifora, Joachim Lupberger, Michael Nassal, Glenn S Cowley, Naoto Fujiwara, Sen-Yung Hsieh, Yujin Hoshida, Emanuele Felli, Patrick Pessaux, Camille Sureau, Catherine Schuster, David E Root, Thomas F Baumert, Thomas F Baumert
A genome-wide gain-of-function screen identifies CDKN2C as a HBV host factor. Nature communications 11 (1) (2020)
Pratiti Bandopadhayay, Frederica Piccioni, Ryan O'Rourke, Patricia Ho, Elizabeth M Gonzalez, Graham Buchan, Kenin Qian, Gabrielle Gionet, Emily Girard, Margo Coxon, Matthew G Rees, Lisa Brenan, Frank Dubois, Ofer Shapira, Noah F Greenwald, Melanie Pages, Amanda Balboni Iniguez, Brenton R Paolella, Alice Meng, Claire Sinai, Giovanni Roti, Neekesh V Dharia, Amanda Creech, Benjamin Tanenbaum, Prasidda Khadka, Adam Tracy, Hong L Tiv, Andrew L Hong, Shannon Coy, Rumana Rashid, Jia-Ren Lin, Glenn S Cowley, Fred C Lam, Amy Goodale, Yenarae Lee, Kathleen Schoolcraft, Francisca Vazquez, William C Hahn, Aviad Tsherniak, James E Bradner, Michael B Yaffe, Till Milde, Stefan M Pfister, Jun Qi, Monica Schenone, Steven A Carr, Keith L Ligon, Mark W Kieran, Sandro Santagata, James M Olson, Prafulla C Gokhale, Jacob D Jaffe, David E Root, Kimberly Stegmaier, Cory M Johannessen, Rameen Beroukhim
Neuronal differentiation and cell-cycle programs mediate response to BET-bromodomain inhibition in MYC-driven medulloblastoma. Nature communications 10 (1) (2019)
Kendall R Sanson, Ruth E Hanna, Mudra Hegde, Katherine F Donovan, Christine Strand, Meagan E Sullender, Emma W Vaimberg, Amy Goodale, David E Root, Frederica Piccioni, John G Doench
Optimized libraries for CRISPR-Cas9 genetic screens with multiple modalities. Nature communications 9 (1) (2018)
Andrew O Giacomelli, Xiaoping Yang, Robert E Lintner, James M McFarland, Marc Duby, Jaegil Kim, Thomas P Howard, David Y Takeda, Seav Huong Ly, Eejung Kim, Hugh S Gannon, Brian Hurhula, Ted Sharpe, Amy Goodale, Briana Fritchman, Scott Steelman, Francisca Vazquez, Aviad Tsherniak, Andrew J Aguirre, John G Doench, Frederica Piccioni, Charles W M Roberts, Matthew L Meyerson, Gad A Getz, Cory M Johannessen, David E Root, William C Hahn
Mutational processes shape the landscape of TP53 mutations in human cancer. Nature genetics 50 (10) (2018)

Frederica Piccioni.css-eqlu8i{font-size:small;padding-left:4px;} (F Piccioni, Federica Piccioni)

Publication Activity (10 Years)

Top Topics

Top Venues

Frederica Piccioni (F Piccioni, Federica Piccioni)