Nicholas M Pearce (Nicholas Pearce)

Publication Activity (10 Years)

Years Active: 2017-2022
Publications (10 Years): 8

Top Topics

Molecular Dynamics Simulations

Crystal Structure

Top Venues

Angewandte Chemie (International ed. in English)

Acta crystallographica. Section D, Structural biology

Chemical science

PLoS computational biology

This page only lists publications with an associated author ORCID identifier.

Publications

Manfred S Weiss, Jan Wollenhaupt, Galen J Correy, Brian K Shoichet, Andreas Heine, Gerhard Klebe, Tobias Krojer, Marjolein Thunissen, Nicholas M Pearce
Of problems and opportunities-How to treat and how to not treat crystallographic fragment screening data. Protein science : a publication of the Protein Society 31 (9) (2022)
Thomas M Wood, Matthieu R Zeronian, Ned Buijs, Kristine Bertheussen, Hanieh K Abedian, Aidan V Johnson, Nicholas M Pearce, Martin Lutz, Johan Kemmink, Tjalling Seirsma, Leendert W Hamoen, Bert J C Janssen, Nathaniel I Martin
Mechanistic insights into the C 55 -P targeting lipopeptide antibiotics revealed by structure-activity studies and high-resolution crystal structures. Chemical science 13 (10) (2022)
Mathias Wendt, Rosa Bellavita, Alan Gerber, Nina-Louisa Efrém, Thirza van Ramshorst, Nicholas M Pearce, Paul R J Davey, Isabel Everard, Mercedes Vazquez-Chantada, Elisabetta Chiarparin, Paolo Grieco, Sven Hennig, Tom N Grossmann
Bicyclic β-Sheet Mimetics that Target the Transcriptional Coactivator β-Catenin and Inhibit Wnt Signaling. Angewandte Chemie (International ed. in English) 60 (25) (2021)
Nicholas M Pearce, Piet Gros
A method for intuitively extracting macromolecular dynamics from structural disorder. Nature communications 12 (1) (2021)
Nicoleta T Ploscariu, Tom Burnley, Piet Gros, Nicholas M Pearce
Improving sampling of crystallographic disorder in ensemble refinement. Acta crystallographica. Section D, Structural biology 77 (Pt 11) (2021)
Wout Oosterheert, Katerina T Xenaki, Viviana Neviani, Wouter Pos, Sofia Doulkeridou, Jip Manshande, Nicholas M Pearce, Loes M J Kroon-Batenburg, Martin Lutz, Paul M P van Bergen En Henegouwen, Piet Gros
Implications for tetraspanin-enriched microdomain assembly based on structures of CD9 with EWI-F. Life science alliance 3 (11) (2020)
Daniel A Keedy, Zachary B Hill, Justin T Biel, Emily Kang, T Justin Rettenmaier, José Brandão-Neto, Nicholas M Pearce, Frank von Delft, James A Wells, Brian K Shoichet
An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering. eLife 7 (2018)
Samuel Demharter, Nicholas M Pearce, Kylie Beattie, Isabel Frost, Jinwoo Leem, Alistair Martin, Robert Oppenheimer, Cristian Regep, Tammo Rukat, Alexander Skates, Nicola Trendel, David J Gavaghan, Charlotte M Deane, Bernhard Knapp
Ten simple rules for surviving an interdisciplinary PhD. PLoS computational biology 13 (5) (2017)