Nikolaos G Sgourakis

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 25

Top Venues

Nature communications

bioRxiv : the preprint server for biology

Proceedings of the National Academy of Sciences of the United States of America

Science advances

University of Pennsylvania

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Pennsylvania Jul 01 2020

United States

Associate Professor :: Biochemistry and Biophysics

Publications

Richard J Gilbertson, Sam Behjati, Anna-Lisa Böttcher, Marianne E Bronner, Matthew Burridge, Henrick Clausing, Harry Clifford, Tracey Danaher, Laura K Donovan, Jarno Drost, Alexander M M Eggermont, Chris Emerson, Mona G Flores, Petra Hamerlik, Nada Jabado, Andrew Jones, Henrick Kaessmann, Claudia L Kleinman, Marcel Kool, Lena M Kutscher, Gavin Lindberg, Emily Linnane, John C Marioni, John M Maris, Michelle Monje, Alexandra Macaskill, Steven A Niederer, Paul A Northcott, Elizabeth Peeters, Willemijn Plieger-van Solkema, Liane Preußner, Anne C Rios, Karsten Rippe, Peter Sandford, Nikolaos G Sgourakis, Adam Shlien, Pete Smith, Karin Straathof, Patrick J Sullivan, Mario L Suvà, Michael D Taylor, Emma Thompson, Roser Vento-Tormo, Brandon J Wainwright, Robert J Wechsler-Reya, Frank Westermann, Shannon Winslade, Bissan Al-Lazikani, Stefan M Pfister
The Virtual Child. Cancer discovery 14 (4) (2024)
Sagar Gupta, Nikolaos G Sgourakis
A structure-guided approach to predict MHC-I restriction of T cell receptors for public antigens. bioRxiv : the preprint server for biology (2024)
Yi Sun, Tyler J Florio, Sagar Gupta, Michael C Young, Quinlen F Marshall, Samuel E Garfinkle, Georgia F Papadaki, Hau V Truong, Emily Mycek, Peiyao Li, Alvin Farrel, Nicole L Church, Shereen Jabar, Matthew D Beasley, Ben R Kiefel, Mark Yarmarkovich, Leena Mallik, John M Maris, Nikolaos G Sgourakis
Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion. Science immunology 8 (90) (2023)
Yi Sun, Tyler J Florio, Sagar Gupta, Michael C Young, Quinlen F Marshall, Samuel E Garfinkle, Georgia F Papadaki, Hau V Truong, Emily Mycek, Peiyao Li, Alvin Farrel, Nicole L Church, Shereen Jabar, Matthew D Beasley, Ben R Kiefel, Mark Yarmarkovich, Leena Mallik, John M Maris, Nikolaos G Sgourakis
Structural principles of peptide-centric Chimeric Antigen Receptor recognition guide therapeutic expansion. bioRxiv : the preprint server for biology (2023)
Yi Sun, Georgia F Papadaki, Christine A Devlin, Julia N Danon, Michael C Young, Trenton J Winters, George M Burslem, Erik Procko, Nikolaos G Sgourakis
Xeno interactions between MHC-I proteins and molecular chaperones enable ligand exchange on a broad repertoire of HLA allotypes. Science advances 9 (8) (2023)
Sagar Gupta, Santrupti Nerli, Sreeja Kutti Kandy, Glenn L Mersky, Nikolaos G Sgourakis
HLA3DB: comprehensive annotation of peptide/HLA complexes enables blind structure prediction of T cell epitopes. Nature communications 14 (1) (2023)
Yi Sun, Georgia F Papadaki, Christine A Devlin, Julia N Danon, Michael C Young, Trenton J Winters, George M Burslem, Erik Procko, Nikolaos G Sgourakis
Xeno interactions between MHC-I proteins and molecular chaperones enable ligand exchange on a broad repertoire of HLA allotypes. Science advances 9 (8) (2023)
Yi Sun, Georgia F Papadaki, Christine A Devlin, Julia N Danon, Michael C Young, Trenton J Winters, George M Burslem, Erik Procko, Nikolaos G Sgourakis
Xeno interactions between MHC-I proteins and molecular chaperones enable ligand exchange on a broad repertoire of HLA allotypes. Science advances 9 (8) (2023)
Yi Sun, Georgia F Papadaki, Christine A Devlin, Julia N Danon, Michael C Young, Trenton J Winters, George M Burslem, Erik Procko, Nikolaos G Sgourakis
Xeno interactions between MHC-I proteins and molecular chaperones enable ligand exchange on a broad repertoire of HLA allotypes. Science advances 9 (8) (2023)
Sagar Gupta, Santrupti Nerli, Sreeja Kutti Kandy, Glenn L Mersky, Nikolaos G Sgourakis
HLA3DB: comprehensive annotation of peptide/HLA complexes enables blind structure prediction of T cell epitopes. bioRxiv : the preprint server for biology (2023)
Yi Sun, Michael C Young, Claire H Woodward, Julia N Danon, Hau Truong, Sagar Gupta, Trenton J Winters, George M Burslem, Nikolaos G Sgourakis
Universal open MHC-I molecules for rapid peptide loading and enhanced complex stability across HLA allotypes. bioRxiv : the preprint server for biology (2023)
Andrew C McShan, David Flores-Solis, Yi Sun, Samuel E Garfinkle, Jugmohit S Toor, Michael C Young, Nikolaos G Sgourakis
Conformational plasticity of RAS Q61 family of neoepitopes results in distinct features for targeted recognition. Nature communications 14 (1) (2023)
Yi Sun, Michael C Young, Claire H Woodward, Julia N Danon, Hau V Truong, Sagar Gupta, Trenton J Winters, Joan Font-Burgada, George M Burslem, Nikolaos G Sgourakis
Universal open MHC-I molecules for rapid peptide loading and enhanced complex stability across HLA allotypes. Proceedings of the National Academy of Sciences of the United States of America 120 (25) (2023)
Andrew C McShan, Christine A Devlin, Georgia F Papadaki, Yi Sun, Adam I Green, Giora I Morozov, George M Burslem, Erik Procko, Nikolaos G Sgourakis
TAPBPR employs a ligand-independent docking mechanism to chaperone MR1 molecules. Nature chemical biology 18 (8) (2022)
Jiansheng Jiang, Daniel K Taylor, Ellen J Kim, Lisa F Boyd, Javeed Ahmad, Michael G Mage, Hau V Truong, Claire H Woodward, Nikolaos G Sgourakis, Peter Cresswell, David H Margulies, Kannan Natarajan
Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation. Nature communications 13 (1) (2022)
Andrew C McShan, Christine A Devlin, Giora I Morozov, Sarah A Overall, Danai Moschidi, Neha Akella, Erik Procko, Nikolaos G Sgourakis
TAPBPR promotes antigen loading on MHC-I molecules using a peptide trap. Nature communications 12 (1) (2021)
Santrupti Nerli, Viviane S De Paula, Andrew C McShan, Nikolaos G Sgourakis
Backbone-independent NMR resonance assignments of methyl probes in large proteins. Nature communications 12 (1) (2021)
Viviane S De Paula, Kevin M Jude, Santrupti Nerli, Caleb R Glassman, K Christopher Garcia, Nikolaos G Sgourakis
Interleukin-2 druggability is modulated by global conformational transitions controlled by a helical capping switch. Proceedings of the National Academy of Sciences of the United States of America 117 (13) (2020)
Soumya P Behera, Abhinav Dubey, Wan-Na Chen, Viviane S De Paula, Meng Zhang, Nikolaos G Sgourakis, Wolfgang Bermel, Gerhard Wagner, Paul W Coote, Haribabu Arthanari
Nearest-neighbor NMR spectroscopy: categorizing spectral peaks by their adjacent nuclei. Nature communications 11 (1) (2020)
Kathy Y Wei, Danai Moschidi, Matthew J Bick, Santrupti Nerli, Andrew C McShan, Lauren P Carter, Po-Ssu Huang, Daniel A Fletcher, Nikolaos G Sgourakis, Scott E Boyken, Julien S Baker
Computational design of closely related proteins that adopt two well-defined but structurally divergent folds. Proceedings of the National Academy of Sciences of the United States of America 117 (13) (2020)
Santrupti Nerli, Nikolaos G Sgourakis
Structure-based modeling of SARS-CoV-2 peptide/HLA-A02 antigens. bioRxiv : the preprint server for biology (2020)
Aimee H Marceau, Caileen M Brison, Santrupti Nerli, Heather E Arsenault, Andrew C McShan, Eefei Chen, Hsiau-Wei Lee, Jennifer A Benanti, Nikolaos G Sgourakis, Seth M Rubin
An order-to-disorder structural switch activates the FoxM1 transcription factor. eLife 8 (2019)
Andrew C McShan, Christine A Devlin, Sarah A Overall, Jihye Park, Jugmohit S Toor, Danai Moschidi, David Flores-Solis, Hannah Choi, Sarvind M Tripathi, Erik Procko, Nikolaos G Sgourakis
Molecular determinants of chaperone interactions on MHC-I for folding and antigen repertoire selection. Proceedings of the National Academy of Sciences of the United States of America 116 (51) (2019)
Jooyoung Park, Brinda Selvaraj, Andrew C McShan, Scott E Boyken, Kathy Y Wei, Gustav Oberdorfer, William DeGrado, Nikolaos G Sgourakis, Matthew J Cuneo, Dean A A Myles, Julien S Baker
De novo design of a homo-trimeric amantadine-binding protein. eLife 8 (2019)
Viviane S De Paula, Nikolaos G Sgourakis, Ivo M B Francischetti, Fabio Ceneviva Lacerda de Almeida, Robson Q Monteiro, Ana Paula Valente
NMR structure determination of Ixolaris and factor X(a) interaction reveals a noncanonical mechanism of Kunitz inhibition. Blood 134 (8) (2019)

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Publication Activity (10 Years)

Top Topics

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Nikolaos G Sgourakis