Kevin M Jude (Kevin Jude)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 33

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Nature chemical biology

Science (New York, N.Y.)

Nature

Howard Hughes Medical Institute - Stanford University

University of Pennsylvania (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Howard Hughes Medical Institute - Stanford University

United States

Research Specialist, Structural Biology :: Molecular and Cellular Physiology

University of California Berkeley

United States

postdoc :: Molecular and Cellular Biology

Education History

University of Pennsylvania

United States

PHD :: Chemistry

Georgia Institute of Technology

United States

BSC :: Chemistry

Publications

Hanlun Jiang, Kevin M Jude, Kejia Wu, Jorge Fallas, George Ueda, T J Brunette, Derrick R Hicks, Harley Pyles, Aerin Yang, Lauren Carter, Mila Lamb, Xinting Li, Paul M Levine, Lance J Stewart, K Christopher Garcia, Julien S Baker
De novo design of buttressed loops for sculpting protein functions. Nature chemical biology (2024)
Buwei Huang, Brian Coventry, Marta T Borowska, Dimitrios C Arhontoulis, Marc Exposit, Mohamad Abedi, Kevin M Jude, Samer F Halabiya, Aza Allen, Cami Cordray, Inna Goreshnik, Margaret Ahlrichs, Sidney Chan, Hillary Tunggal, Michelle DeWitt, Nathaniel Hyams, Lauren Carter, Lance J Stewart, Deborah Heydenburg Fuller, Ying Mei, K Christopher Garcia, Julien S Baker
De novo design of miniprotein antagonists of cytokine storm inducers. Nature communications 15 (1) (2024)
Hanlun Jiang, Kevin M Jude, Kejia Wu, Jorge Fallas, George Ueda, T J Brunette, Derrick R Hicks, Harley Pyles, Aerin Yang, Lauren Carter, Mila Lamb, Xinting Li, Paul M Levine, Lance J Stewart, K Christopher Garcia, Julien S Baker
De novo design of buttressed loops for sculpting protein functions. Nature chemical biology 20 (8) (2024)
Buwei Huang, Brian Coventry, Marta T Borowska, Dimitrios C Arhontoulis, Marc Exposit, Mohamad Abedi, Kevin M Jude, Samer F Halabiya, Aza Allen, Cami Cordray, Inna Goreshnik, Margaret Ahlrichs, Sidney Chan, Hillary Tunggal, Michelle DeWitt, Nathaniel Hyams, Lauren Carter, Lance J Stewart, Deborah Heydenburg Fuller, Ying Mei, K Christopher Garcia, Julien S Baker
De novo design of miniprotein antagonists of cytokine storm inducers. Nature communications 15 (1) (2024)
Buwei Huang, Brian Coventry, Marta T Borowska, Dimitrios C Arhontoulis, Marc Exposit, Mohamad Abedi, Kevin M Jude, Samer F Halabiya, Aza Allen, Cami Cordray, Inna Goreshnik, Margaret Ahlrichs, Sidney Chan, Hillary Tunggal, Michelle DeWitt, Nathaniel Hyams, Lauren Carter, Lance J Stewart, Deborah Heydenburg Fuller, Ying Mei, K Christopher Garcia, Julien S Baker
De novo design of miniprotein antagonists of cytokine storm inducers. Nature communications 15 (1) (2024)
Hanlun Jiang, Kevin M Jude, Kejia Wu, Jorge Fallas, George Ueda, T J Brunette, Derrick R Hicks, Harley Pyles, Aerin Yang, Lauren Carter, Mila Lamb, Xinting Li, Paul M Levine, Lance J Stewart, K Christopher Garcia, Julien S Baker
De novo design of buttressed loops for sculpting protein functions. Nature chemical biology 20 (8) (2024)
Nan Wang, Deepa Waghray, Nathanael A Caveney, Kevin M Jude, K Christopher Garcia
Structural insights into human MHC-II association with invariant chain. Proceedings of the National Academy of Sciences of the United States of America 121 (19) (2024)
Nan Wang, Deepa Waghray, Nathanael A Caveney, Kevin M Jude, K Christopher Garcia
Structural insights into human MHC-II association with invariant chain. Proceedings of the National Academy of Sciences of the United States of America 121 (19) (2024)
Hanlun Jiang, Kevin M Jude, Kejia Wu, Jorge Fallas, George Ueda, T J Brunette, Derrick R Hicks, Harley Pyles, Aerin Yang, Lauren Carter, Mila Lamb, Xinting Li, Paul M Levine, Lance J Stewart, K Christopher Garcia, Julien S Baker
De novo design of buttressed loops for sculpting protein functions. Nature chemical biology 20 (8) (2024)
Nan Wang, Deepa Waghray, Nathanael A Caveney, Kevin M Jude, K Christopher Garcia
Structural insights into human MHC-II association with invariant chain. Proceedings of the National Academy of Sciences of the United States of America 121 (19) (2024)
Hanlun Jiang, Kevin M Jude, Kejia Wu, Jorge Fallas, George Ueda, T J Brunette, Derrick R Hicks, Harley Pyles, Aerin Yang, Lauren Carter, Mila Lamb, Xinting Li, Paul M Levine, Lance J Stewart, K Christopher Garcia, Julien S Baker
De novo design of buttressed loops for sculpting protein functions. Nature chemical biology (2024)
Hanlun Jiang, Kevin M Jude, Kejia Wu, Jorge Fallas, George Ueda, T J Brunette, Derrick R Hicks, Harley Pyles, Aerin Yang, Lauren Carter, Mila Lamb, Xinting Li, Paul M Levine, Lance Stewart, K Christopher Garcia, Julien S Baker
De novo design of buttressed loops for sculpting protein functions. bioRxiv : the preprint server for biology (2023)
Aerin Yang, Kevin M Jude, Ben Lai, Mason Minot, Anna M Kocyla, Caleb R Glassman, Daisuke Nishimiya, Yoon Seok Kim, Sai T Reddy, Aly A Khan, K Christopher Garcia
Deploying synthetic coevolution and machine learning to engineer protein-protein interactions. Science (New York, N.Y.) 381 (6656) (2023)
Naotaka Tsutsumi, Sunhee Hwang, Deepa Waghray, Simon Hansen, Kevin M Jude, Nan Wang, Yi Miao, Caleb R Glassman, Nathanael A Caveney, Claudia Y Janda, Rami N Hannoush, K Christopher Garcia
Structure of the Wnt-Frizzled-LRP6 initiation complex reveals the basis for coreceptor discrimination. Proceedings of the National Academy of Sciences of the United States of America 120 (11) (2023)
Naotaka Tsutsumi, Sunhee Hwang, Deepa Waghray, Simon Hansen, Kevin M Jude, Nan Wang, Yi Miao, Caleb R Glassman, Nathanael A Caveney, Claudia Y Janda, Rami N Hannoush, K Christopher Garcia
Structure of the Wnt-Frizzled-LRP6 initiation complex reveals the basis for coreceptor discrimination. Proceedings of the National Academy of Sciences of the United States of America 120 (11) (2023)
Huilin Yang, Umut Y Ulge, Alfredo Quijano-Rubio, Zachary J Bernstein, David R Maestas, Jung-Ho Chun, Wentao Wang, Jian-Xin Lin, Kevin M Jude, Srujan Singh, Brian T Orcutt-Jahns, Peng Li, Jody Mou, Liam Chung, Yun-Huai Kuo, Yasmin H Ali, Aaron S Meyer, Warren L Grayson, Nicola M Heller, K Christopher Garcia, Warren J Leonard, Daniel Adriano Silva, Jennifer H Elisseeff, Julien S Baker, Jamie B Spangler
Design of cell-type-specific hyperstable IL-4 mimetics via modular de novo scaffolds. Nature chemical biology (2023)
Naotaka Tsutsumi, Shoji Maeda, Qianhui Qu, Martin Vögele, Kevin M Jude, Carl-Mikael Suomivuori, Ouliana Panova, Deepa Waghray, Hideaki E Kato, Andrew Velasco, Ron O Dror, Georgios Skiniotis, Brian K Kobilka, K Christopher Garcia
Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins. Science advances 8 (3) (2022)
Caleb R Glassman, Naotaka Tsutsumi, Robert A Saxton, Patrick J Lupardus, Kevin M Jude, K Christopher Garcia
Structure of a Janus kinase cytokine receptor complex reveals the basis for dimeric activation. Science (New York, N.Y.) 376 (6589) (2022)
Junming Ren, Alexander E Chu, Kevin M Jude, Lora K Picton, Aris J Kare, Leon L Su, Alejandra Montano Romero, Po-Ssu Huang, K Christopher Garcia
Interleukin-2 superkines by computational design. Proceedings of the National Academy of Sciences of the United States of America 119 (12) (2022)
Xiang Zhao, Elizabeth Motunrayo Kolawole, Waipan Chan, Yinnian Feng, Xinbo Yang, Marvin H Gee, Kevin M Jude, Leah V Sibener, Polly Morrell Fordyce, Ronald N Germain, Brian D Evavold, K Christopher Garcia
Tuning T cell receptor sensitivity through catch bond engineering. Science (New York, N.Y.) 376 (6589) (2022)
Xinbo Yang, Lee I Garner, Ivan V Zvyagin, Michael A Paley, Ekaterina A Komech, Kevin M Jude, Xiang Zhao, Ricardo A Fernandes, Lynn M Hassman, Grace L Paley, Christina S Savvides, Simon Brackenridge, Max N Quastel, Dmitriy M Chudakov, Paul Bowness, Wayne M Yokoyama, Andrew J McMichael, Geraldine M Gillespie, K Christopher Garcia
Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature (2022)
Steven C Wilson, Nathanael A Caveney, Michelle Yen, Christoph Pollmann, Xinyu Xiang, Kevin M Jude, Maximillian Hafer, Naotaka Tsutsumi, Jacob Piehler, K Christopher Garcia
Organizing structural principles of the IL-17 ligand-receptor axis. Nature 609 (7927) (2022)
Tobias V Lanz, R Camille Brewer, Peggy Pui-Kay Ho, Jae-Seung Moon, Kevin M Jude, Daniel Fernández, Ricardo A Fernandes, Alejandro M Gomez, Gabriel-Stefan Nadj, Christopher M Bartley, Ryan D Schubert, Isobel A Hawes, Sara E Vazquez, Manasi Iyer, J Bradley Zuchero, Bianca Teegen, Jeffrey E Dunn, Christopher B Lock, Lucas B Kipp, Victoria C Cotham, Beatrix M Ueberheide, Blake T Aftab, Mark S Anderson, Joseph L DeRisi, Michael R Wilson, Rachael J M Bashford-Rogers, Michael Platten, K Christopher Garcia, Lawrence Steinman, William H Robinson
Clonally expanded B cells in multiple sclerosis bind EBV EBNA1 and GlialCAM. Nature 603 (7900) (2022)
Nathanael A Caveney, Caleb R Glassman, Kevin M Jude, Naotaka Tsutsumi, K Christopher Garcia
Structure of the IL-27 quaternary receptor signaling complex. eLife 11 (2022)
Longxing Cao, Brian Coventry, Inna Goreshnik, Buwei Huang, William Sheffler, Joon Sung Park, Kevin M Jude, Iva Marković, Rameshwar U Kadam, Koen H G Verschueren, Kenneth Verstraete, Scott Thomas Russell Walsh, Nathaniel Bennett, Ashish Phal, Aerin Yang, Lisa Kozodoy, Michelle DeWitt, Lora K Picton, Lauren Miller, Eva-Maria Strauch, Nicholas D DeBouver, Allison Pires, Asim K Bera, Samer Halabiya, Bradley Hammerson, Wei Yang, Steffen Bernard, Lance J Stewart, Ian A Wilson, Hannele Ruohola-Baker, Joseph Schlessinger, Sangwon Lee, Savvas N Savvides, K Christopher Garcia, Julien S Baker
Design of protein-binding proteins from the target structure alone. Nature 605 (7910) (2022)
Naotaka Tsutsumi, Somnath Mukherjee, Deepa Waghray, Claudia Y Janda, Kevin M Jude, Yi Miao, John S Burg, Nanda Gowtham Aduri, Anthony A Kossiakoff, Cornelius Gati, K Christopher Garcia
Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling. eLife 9 (2020)
Viviane S De Paula, Kevin M Jude, Santrupti Nerli, Caleb R Glassman, K Christopher Garcia, Nikolaos G Sgourakis
Interleukin-2 druggability is modulated by global conformational transitions controlled by a helical capping switch. Proceedings of the National Academy of Sciences of the United States of America 117 (13) (2020)
Luke T Dang, Yi Miao, Andrew Ha, Kanako Yuki, Keunwan Park, Claudia Y Janda, Kevin M Jude, Kritika Mohan, Nhi Ha, Mario Vallon, Jenny Yuan, José G Vilches-Moure, Calvin J Kuo, K Christopher Garcia, Julien S Baker
Receptor subtype discrimination using extensive shape complementary designed interfaces. Nature structural & molecular biology 26 (6) (2019)
Jamie B Spangler, Ignacio Moraga, Kevin M Jude, Christina S Savvides, K Christopher Garcia
A strategy for the selection of monovalent antibodies that span protein dimer interfaces. The Journal of biological chemistry 294 (38) (2019)
Kritika Mohan, George Ueda, Ah Ram Kim, Kevin M Jude, Jorge A Fallas, Yu Guo, Maximillian Hafer, Yi Miao, Robert A Saxton, Jacob Piehler, Vijay G Sankaran, Julien S Baker, K Christopher Garcia
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis. Science (New York, N.Y.) 364 (6442) (2019)
Timothy F Miles, Katja Spiess, Kevin M Jude, Naotaka Tsutsumi, John S Burg, Jessica R Ingram, Deepa Waghray, Gertrud M Hjorto, Olav Larsen, Hidde L Ploegh, Mette M Rosenkilde, K Christopher Garcia
Viral GPCR US28 can signal in response to chemokine agonists of nearly unlimited structural degeneracy. eLife 7 (2018)
Eleonora Trotta, Paul H Bessette, Stephanie L Silveria, Lauren K Ely, Kevin M Jude, Duy T Le, Charles R Holst, Anthony Coyle, Marc Potempa, Lewis L Lanier, K Christopher Garcia, Natasha K Crellin, Isaac J Rondon, Jeffrey A Bluestone
A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism. Nature medicine 24 (7) (2018)
Jonathan T Sockolosky, Eleonora Trotta, Giulia Parisi, Lora K Picton, Leon L Su, Alan C Le, Akanksha Chhabra, Stephanie L Silveria, Benson M George, Indigo C King, Matthew R Tiffany, Kevin M Jude, Leah V Sibener, Julien S Baker, Judith A Shizuru, Antoni Ribas, Jeffrey A Bluestone, K Christopher Garcia
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes. Science (New York, N.Y.) 359 (6379) (2018)

Kevin M Jude.css-eqlu8i{font-size:small;padding-left:4px;} (Kevin Jude)

Publication Activity (10 Years)

Top Topics

Top Venues

Kevin M Jude (Kevin Jude)