Po-Ssu Huang

ORCID

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 29

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Nature biotechnology

bioRxiv : the preprint server for biology

Nature

Stanford University

California Institute of Technology (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Stanford University Oct 01 2016

United States

Assistant Professor :: Bioengineering

Education History

California Institute of Technology

United States

PHD :: Biochemistry and Molecular Biophysics

Publications

Haotian Du, Jingjia Liu, Kevin M Jude, Xinbo Yang, Ying Li, Braxton Bell, Hongli Yang, Audrey Kassardjian, Ali Mobedi, Udit Parekh, R Andres Parra Sperberg, Jean-Philippe Julien, Elizabeth D Mellins, K Christopher Garcia, Po-Ssu Huang
A general platform for targeting MHC-II antigens via a single loop. bioRxiv : the preprint server for biology (2024)
Alexander E Chu, Tianyu Lu, Po-Ssu Huang
Sparks of function by de novo protein design. Nature biotechnology 42 (2) (2024)
Alexander E Chu, Tianyu Lu, Po-Ssu Huang
Sparks of function by de novo protein design. Nature biotechnology 42 (2) (2024)
Alexander E Chu, Jinho Kim, Lucy Cheng, Gina El Nesr, Minkai Xu, Richard W Shuai, Po-Ssu Huang
An all-atom protein generative model. Proceedings of the National Academy of Sciences of the United States of America 121 (27) (2024)
Haotian Du, Jingjia Liu, Kevin M Jude, Xinbo Yang, Ying Li, Braxton Bell, Hongli Yang, Audrey Kassardjian, Ali Mobedi, Udit Parekh, R Andres Parra Sperberg, Jean-Philippe Julien, Elizabeth D Mellins, K Christopher Garcia, Po-Ssu Huang
A general platform for targeting MHC-II antigens via a single loop. bioRxiv : the preprint server for biology (2024)
Haotian Du, Jingjia Liu, Kevin M Jude, Xinbo Yang, Ying Li, Braxton Bell, Hongli Yang, Audrey Kassardjian, Ali Mobedi, Udit Parekh, R Andres Parra Sperberg, Jean-Philippe Julien, Elizabeth D Mellins, K Christopher Garcia, Po-Ssu Huang
A general platform for targeting MHC-II antigens via a single loop. bioRxiv : the preprint server for biology (2024)
Alexander E Chu, Tianyu Lu, Po-Ssu Huang
Sparks of function by de novo protein design. Nature biotechnology 42 (2) (2024)
Alexander E Chu, Tianyu Lu, Po-Ssu Huang
Sparks of function by de novo protein design. Nature biotechnology 42 (2) (2024)
Alexander E Chu, Jinho Kim, Lucy Cheng, Gina El Nesr, Minkai Xu, Richard W Shuai, Po-Ssu Huang
An all-atom protein generative model. Proceedings of the National Academy of Sciences of the United States of America 121 (27) (2024)
Haotian Du, Jingjia Liu, Kevin M Jude, Xinbo Yang, Ying Li, Braxton Bell, Hongli Yang, Audrey Kassardjian, Ali Mobedi, Udit Parekh, R Andres Parra Sperberg, Jean-Philippe Julien, Elizabeth D Mellins, K Christopher Garcia, Po-Ssu Huang
A general platform for targeting MHC-II antigens via a single loop. bioRxiv : the preprint server for biology (2024)
Alexander E Chu, Tianyu Lu, Po-Ssu Huang
Sparks of function by de novo protein design. Nature biotechnology 42 (2) (2024)
Alexander E Chu, Jinho Kim, Lucy Cheng, Gina El Nesr, Minkai Xu, Richard W Shuai, Po-Ssu Huang
An all-atom protein generative model. Proceedings of the National Academy of Sciences of the United States of America 121 (27) (2024)
Alexander E Chu, Tianyu Lu, Po-Ssu Huang
Sparks of function by de novo protein design. Nature biotechnology 42 (2) (2024)
Haotian Du, Jingjia Liu, Kevin M Jude, Xinbo Yang, Ying Li, Braxton Bell, Hongli Yang, Audrey Kassardjian, Ali Mobedi, Udit Parekh, R Andres Parra Sperberg, Jean-Philippe Julien, Elizabeth D Mellins, K Christopher Garcia, Po-Ssu Huang
A general platform for targeting MHC-II antigens via a single loop. bioRxiv : the preprint server for biology (2024)
Alexander E Chu, Tianyu Lu, Po-Ssu Huang
Sparks of function by de novo protein design. Nature biotechnology 42 (2) (2024)
Haotian Du, Jingjia Liu, Kevin M Jude, Xinbo Yang, Ying Li, Braxton Bell, Hongli Yang, Audrey Kassardjian, Ali Mobedi, Udit Parekh, R Andres Parra Sperberg, Jean-Philippe Julien, Elizabeth D Mellins, K Christopher Garcia, Po-Ssu Huang
A general platform for targeting MHC-II antigens via a single loop. bioRxiv : the preprint server for biology (2024)
Alexander E Chu, Tianyu Lu, Po-Ssu Huang
Sparks of function by de novo protein design. Nature biotechnology 42 (2) (2024)
Alexander E Chu, Jinho Kim, Lucy Cheng, Gina El Nesr, Minkai Xu, Richard W Shuai, Po-Ssu Huang
An all-atom protein generative model. Proceedings of the National Academy of Sciences of the United States of America 121 (27) (2024)
Laetitia E Misson, Hejun Liu, Gabriel Ozorowski, Quoc Tran, Jordan L Woehl, Irene Khalek, Jessica M Smith, Shawn Barman, Fangzhu Zhao, Celina Keating, Oliver Limbo, Megan Verma, Jingjia Liu, Robyn L Stanfield, Xueyong Zhu, Hannah L Turner, Devin Sok, Po-Ssu Huang, Dennis R Burton, Andrew B Ward, Ian A Wilson, Joseph G Jardine
Fully synthetic platform to rapidly generate tetravalent bispecific nanobody-based immunoglobulins. Proceedings of the National Academy of Sciences of the United States of America 120 (24) (2023)
Michael Westberg, Daesun Song, Vandon Duong, Daniel Fernández, Po-Ssu Huang, Michael Z Lin
Photoswitchable binders enable temporal dissection of endogenous protein function. bioRxiv : the preprint server for biology (2023)
Alexander E Chu, Lucy Cheng, Gina El Nesr, Minkai Xu, Po-Ssu Huang
An all-atom protein generative model. bioRxiv : the preprint server for biology (2023)
Alexander E Chu, Daniel Fernández, Jingjia Liu, Raphael R Eguchi, Po-Ssu Huang
De Novo Design of a Highly Stable Ovoid TIM Barrel: Unlocking Pocket Shape towards Functional Design. Biodesign research 2022 (2022)
Namrata Anand, Raphael R Eguchi, Irimpan I Mathews, Carla P Perez, Alexander Derry, Russ B Altman, Po-Ssu Huang
Protein sequence design with a learned potential. Nature communications 13 (1) (2022)
Junming Ren, Alexander E Chu, Kevin M Jude, Lora K Picton, Aris J Kare, Leon L Su, Alejandra Montano Romero, Po-Ssu Huang, K Christopher Garcia
Interleukin-2 superkines by computational design. Proceedings of the National Academy of Sciences of the United States of America 119 (12) (2022)
Raphael R Eguchi, Christian A Choe, Po-Ssu Huang
Ig-VAE: Generative modeling of protein structure by direct 3D coordinate generation. PLoS computational biology 18 (6) (2022)
Jun W Kim, Cesar P Marquez, R Andres Parra Sperberg, Jiaxiang Wu, Won G Bae, Po-Ssu Huang, E Alejandro Sweet-Cordero, Jennifer R Cochran
Engineering a potent receptor superagonist or antagonist from a novel IL-6 family cytokine ligand. Proceedings of the National Academy of Sciences of the United States of America 117 (25) (2020)
Shane J Caldwell, Ian C Haydon, Nikoletta Piperidou, Po-Ssu Huang, Matthew J Bick, H Sebastian Sjöström, Donald Hilvert, Julien S Baker, Cathleen Zeymer
Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion. Proceedings of the National Academy of Sciences of the United States of America 117 (48) (2020)
Chunfu Xu, Peilong Lu, Tamer M Gamal El-Din, Xue Y Pei, Matthew C Johnson, Atsuko Uyeda, Matthew J Bick, Qi Xu, Daohua Jiang, Hua Bai, Gabriella Reggiano, Yang Hsia, T J Brunette, Jiayi Dou, Dan Ma, Eric M Lynch, Scott E Boyken, Po-Ssu Huang, Lance J Stewart, Frank DiMaio, Justin M Kollman, Ben F Luisi, Tomoaki Matsuura, William A Catterall, Julien S Baker
Computational design of transmembrane pores. Nature 585 (7823) (2020)
Kathy Y Wei, Danai Moschidi, Matthew J Bick, Santrupti Nerli, Andrew C McShan, Lauren P Carter, Po-Ssu Huang, Daniel A Fletcher, Nikolaos G Sgourakis, Scott E Boyken, Julien S Baker
Computational design of closely related proteins that adopt two well-defined but structurally divergent folds. Proceedings of the National Academy of Sciences of the United States of America 117 (13) (2020)

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Publication Activity (10 Years)

Top Topics

Top Venues

Po-Ssu Huang