Aleksandra Filipovska

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 42

Top Venues

Science advances

Nature cell biology

Nature communications

Science (New York, N.Y.)

University of Western Australia

University of Otago (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Western Australia

Australia

Professor and NHMRC Senior Research Fellow :: Centre for Medical Research

Education History

University of Otago

New Zealand

PHD :: Department of Biochemistry

Publications

Laetitia A Hughes, Oliver Rackham, Aleksandra Filipovska
Illuminating mitochondrial translation through mouse models. Human molecular genetics 33 (R1) (2024)
Laetitia A Hughes, Oliver Rackham, Aleksandra Filipovska
Illuminating mitochondrial translation through mouse models. Human molecular genetics 33 (R1) (2024)
Laetitia A Hughes, Oliver Rackham, Aleksandra Filipovska
Illuminating mitochondrial translation through mouse models. Human molecular genetics 33 (R1) (2024)
Martin Saurer, Marc Leibundgut, Hima Priyanka Nadimpalli, Alain Scaiola, Tanja Schönhut, Richard G Lee, Stefan J Siira, Oliver Rackham, René Dreos, Tea Lenarčič, Eva Kummer, David Gatfield, Aleksandra Filipovska, Nenad Ban
Molecular basis of translation termination at noncanonical stop codons in human mitochondria. Science (New York, N.Y.) 380 (6644) (2023)
Martin Saurer, Marc Leibundgut, Hima Priyanka Nadimpalli, Alain Scaiola, Tanja Schönhut, Richard G Lee, Stefan J Siira, Oliver Rackham, René Dreos, Tea Lenarčič, Eva Kummer, David Gatfield, Aleksandra Filipovska, Nenad Ban
Molecular basis of translation termination at noncanonical stop codons in human mitochondria. Science (New York, N.Y.) 380 (6644) (2023)
Richard G Lee, Danielle L Rudler, Samuel A Raven, Liuyu Peng, Anaëlle Chopin, Edward S X Moh, Tim McCubbin, Stefan J Siira, Samuel V Fagan, Nicholas J DeBono, Maike Stentenbach, Jasmin M Browne, Filip F Rackham, Ji Li, Kaylene J Simpson, Esteban Marcellin, Nicolle H Packer, Gavin E Reid, Benjamin Scott Padman, Oliver Rackham, Aleksandra Filipovska
Quantitative subcellular reconstruction reveals a lipid mediated inter-organelle biogenesis network. Nature cell biology 26 (1) (2023)
Louise Uoselis, Runa S J Lindblom, Wai Kit Lam, Catharina J Küng, Marvin Skulsuppaisarn, Grace Khuu, Thanh Ngoc Nguyen, Danielle L Rudler, Aleksandra Filipovska, Ralf Bernd Schittenhelm, Michael Lazarou
Temporal landscape of mitochondrial proteostasis governed by the UPR mt . Science advances 9 (38) (2023)
Martin Saurer, Marc Leibundgut, Hima Priyanka Nadimpalli, Alain Scaiola, Tanja Schönhut, Richard G Lee, Stefan J Siira, Oliver Rackham, René Dreos, Tea Lenarčič, Eva Kummer, David Gatfield, Aleksandra Filipovska, Nenad Ban
Molecular basis of translation termination at noncanonical stop codons in human mitochondria. Science (New York, N.Y.) 380 (6644) (2023)
Laetitia A Hughes, Danielle L Rudler, Stefan J Siira, Tim McCubbin, Samuel A Raven, Jasmin M Browne, Judith A Ermer, Jeanette Rientjes, Jennifer Rodger, Esteban Marcellin, Oliver Rackham, Aleksandra Filipovska
Copy number variation in tRNA isodecoder genes impairs mammalian development and balanced translation. Nature communications 14 (1) (2023)
Chuan-Yang Dai, Chai Chee Ng, Grace Ching Ching Hung, Ina Kirmes, Laetitia A Hughes, Yunguang Du, Christopher A Brosnan, Arnaud Ahier, Anne Hahn, Cole M Haynes, Oliver Rackham, Aleksandra Filipovska, Steven Zuryn
ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription. Nature cell biology (2023)
Richard G Lee, Danielle L Rudler, Samuel A Raven, Liuyu Peng, Anaëlle Chopin, Edward S X Moh, Tim McCubbin, Stefan J Siira, Samuel V Fagan, Nicholas J DeBono, Maike Stentenbach, Jasmin M Browne, Filip F Rackham, Ji Li, Kaylene J Simpson, Esteban Marcellin, Nicolle H Packer, Gavin E Reid, Benjamin Scott Padman, Oliver Rackham, Aleksandra Filipovska
Quantitative subcellular reconstruction reveals a lipid mediated inter-organelle biogenesis network. Nature cell biology (2023)
Maike Stentenbach, Judith A Ermer, Danielle L Rudler, Kara L Perks, Samuel A Raven, Richard G Lee, Tim McCubbin, Esteban Marcellin, Stefan J Siira, Oliver Rackham, Aleksandra Filipovska
Multi-omic profiling reveals an RNA processing rheostat that predisposes to prostate cancer. EMBO molecular medicine (2023)
Richard G Lee, Danielle L Rudler, Samuel A Raven, Liuyu Peng, Anaëlle Chopin, Edward S X Moh, Tim McCubbin, Stefan J Siira, Samuel V Fagan, Nicholas J DeBono, Maike Stentenbach, Jasmin M Browne, Filip F Rackham, Ji Li, Kaylene J Simpson, Esteban Marcellin, Nicolle H Packer, Gavin E Reid, Benjamin Scott Padman, Oliver Rackham, Aleksandra Filipovska
Quantitative subcellular reconstruction reveals a lipid mediated inter-organelle biogenesis network. Nature cell biology 26 (1) (2023)
Maike Stentenbach, Judith A Ermer, Danielle L Rudler, Kara L Perks, Samuel A Raven, Richard G Lee, Tim McCubbin, Esteban Marcellin, Stefan J Siira, Oliver Rackham, Aleksandra Filipovska
Multi-omic profiling reveals an RNA processing rheostat that predisposes to prostate cancer. EMBO molecular medicine (2023)
Richard G Lee, Danielle L Rudler, Samuel A Raven, Liuyu Peng, Anaëlle Chopin, Edward S X Moh, Tim McCubbin, Stefan J Siira, Samuel V Fagan, Nicholas J DeBono, Maike Stentenbach, Jasmin M Browne, Filip F Rackham, Ji Li, Kaylene J Simpson, Esteban Marcellin, Nicolle H Packer, Gavin E Reid, Benjamin Scott Padman, Oliver Rackham, Aleksandra Filipovska
Quantitative subcellular reconstruction reveals a lipid mediated inter-organelle biogenesis network. Nature cell biology 26 (1) (2023)
Martin Saurer, Marc Leibundgut, Hima Priyanka Nadimpalli, Alain Scaiola, Tanja Schönhut, Richard G Lee, Stefan J Siira, Oliver Rackham, René Dreos, Tea Lenarčič, Eva Kummer, David Gatfield, Aleksandra Filipovska, Nenad Ban
Molecular basis of translation termination at noncanonical stop codons in human mitochondria. Science (New York, N.Y.) 380 (6644) (2023)
Maike Stentenbach, Judith A Ermer, Danielle L Rudler, Kara L Perks, Samuel A Raven, Richard G Lee, Tim McCubbin, Esteban Marcellin, Stefan J Siira, Oliver Rackham, Aleksandra Filipovska
Multi-omic profiling reveals an RNA processing rheostat that predisposes to prostate cancer. EMBO molecular medicine (2023)
Oliver Rackham, Aleksandra Filipovska
Organization and expression of the mammalian mitochondrial genome. Nature reviews. Genetics 23 (10) (2022)
Pascal D Vos, Aleksandra Filipovska, Oliver Rackham
Frankenstein Cas9: engineering improved gene editing systems. Biochemical Society transactions 50 (5) (2022)
Jelena Misic, Dusanka Milenkovic, Ali Al-Behadili, Xie Xie, Min Jiang, Shan Jiang, Roberta Filograna, Camilla Koolmeister, Stefan J Siira, Louise Jenninger, Aleksandra Filipovska, Anders R Clausen, Leonardo Caporali, Maria Lucia Valentino, Chiara La Morgia, Valerio Carelli, Thomas J Nicholls, Anna Wredenberg, Maria Falkenberg, Nils-Göran Larsson
Mammalian RNase H1 directs RNA primer formation for mtDNA replication initiation and is also necessary for mtDNA replication completion. Nucleic acids research 50 (15) (2022)
Pascal D Vos, Giulia Rossetti, Jessica L Mantegna, Stefan J Siira, Andrianto P Gandadireja, Mitchell Bruce, Samuel A Raven, Olga Khersonsky, Sarel J Fleishman, Aleksandra Filipovska, Oliver Rackham
Computationally designed hyperactive Cas9 enzymes. Nature communications 13 (1) (2022)
Paula Clemente, Javier Calvo-Garrido, Sarah F Pearce, Florian A Schober, Megumi Shigematsu, Stefan J Siira, Isabelle Laine, Henrik Spåhr, Christian Steinmetzger, Katja Petzold, Yohei Kirino, Rolf Wibom, Oliver Rackham, Aleksandra Filipovska, Joanna Rorbach, Christoph Freyer, Anna Wredenberg
ANGEL2 phosphatase activity is required for non-canonical mitochondrial RNA processing. Nature communications 13 (1) (2022)
Richard G Lee, Shanti Balasubramaniam, Maike Stentenbach, Tom Kralj, Tim McCubbin, Benjamin Padman, Janine Smith, Lisa G Riley, Archana Priyadarshi, Liuyu Peng, Madison R Nuske, Richard Webster, Ken Peacock, Philip Roberts, Zornitza Stark, Gabrielle Lemire, Yoko A Ito, null null, Kym M Boycott, Michael T Geraghty, Jan Bert van Klinken, Sacha Ferdinandusse, Ying Zhou, Rebecca Walsh, Esteban Marcellin, David R Thorburn, Tony Rosciolli, Janice Fletcher, Oliver Rackham, Frederic M Vaz, Gavin E Reid, Aleksandra Filipovska
Deleterious variants in CRLS1 lead to cardiolipin deficiency and cause an autosomal recessive multi-system mitochondrial disease. Human molecular genetics 31 (21) (2022)
Min Jiang, Xie Xie, Xuefeng Zhu, Shan Jiang, Dusanka Milenkovic, Jelena Misic, Yonghong Shi, Nirwan Tandukar, Xinping Li, Ilian Atanassov, Louise Jenninger, Emily Hoberg, Sara Albarran-Gutierrez, Zsolt Szilagyi, Bertil Macao, Stefan J Siira, Valerio Carelli, Jack D Griffith, Claes M Gustafsson, Thomas J Nicholls, Aleksandra Filipovska, Nils-Göran Larsson, Maria Falkenberg
The mitochondrial single-stranded DNA binding protein is essential for initiation of mtDNA replication. Science advances 7 (27) (2021)
Akira Ohkubo, Lindsey Van Haute, Danielle L Rudler, Maike Stentenbach, Florian A Steiner, Oliver Rackham, Michal Minczuk, Aleksandra Filipovska, Jean-Claude Martinou
The FASTK family proteins fine-tune mitochondrial RNA processing. PLoS genetics 17 (11) (2021)
Giulia Rossetti, Judith A Ermer, Maike Stentenbach, Stefan J Siira, Tara R Richman, Dusanka Milenkovic, Kara L Perks, Laetitia A Hughes, Emma L Jamieson, Gulibaikelamu Xiafukaiti, Natalie C Ward, Satoru Takahashi, Nicola Gray, Helena M Viola, Livia C Hool, Oliver Rackham, Aleksandra Filipovska
A common genetic variant of a mitochondrial RNA processing enzyme predisposes to insulin resistance. Science advances 7 (39) (2021)
Tea Lenarčič, Mateusz Jaskolowski, Marc Leibundgut, Alain Scaiola, Tanja Schönhut, Martin Saurer, Richard G Lee, Oliver Rackham, Aleksandra Filipovska, Nenad Ban
Stepwise maturation of the peptidyl transferase region of human mitoribosomes. Nature communications 12 (1) (2021)
Tara R Richman, Judith A Ermer, Stefan J Siira, Irina Kuznetsova, Christopher A Brosnan, Giulia Rossetti, Jessica Baker, Kara L Perks, Henrietta Cserne Szappanos, Helena M Viola, Nicola Gray, Mark Larance, Livia C Hool, Steven Zuryn, Oliver Rackham, Aleksandra Filipovska
Mitochondrial mistranslation modulated by metabolic stress causes cardiovascular disease and reduced lifespan. Aging cell 20 (7) (2021)
Tanya Solomon, Aleksandra Filipovska, Livia Hool, Helena M Viola
Preventative therapeutic approaches for hypertrophic cardiomyopathy. The Journal of physiology 599 (14) (2020)
Danielle L Rudler, Laetitia A Hughes, Helena M Viola, Livia C Hool, Oliver Rackham, Aleksandra Filipovska
Fidelity and coordination of mitochondrial protein synthesis in health and disease. The Journal of physiology 599 (14) (2020)
Richard G Lee, Junjie Gao, Stefan J Siira, Anne-Marie Shearwood, Judith A Ermer, Vinzenz Hofferek, James C Mathews, Minghao Zheng, Gavin E Reid, Oliver Rackham, Aleksandra Filipovska
Cardiolipin is required for membrane docking of mitochondrial ribosomes and protein synthesis. Journal of cell science 133 (14) (2020)
Nicola Ferreira, Christopher E Andoniou, Kara L Perks, Judith A Ermer, Danielle L Rudler, Giulia Rossetti, Ambika Periyakaruppiah, Jamie K Y Wong, Oliver Rackham, Peter G Noakes, Mariapia A Degli-Esposti, Aleksandra Filipovska
Murine cytomegalovirus infection exacerbates complex IV deficiency in a model of mitochondrial disease. PLoS genetics 16 (3) (2020)
Nicola Ferreira, Kara L Perks, Giulia Rossetti, Danielle L Rudler, Laetitia A Hughes, Judith A Ermer, Louis H Scott, Irina Kuznetsova, Tara R Richman, Vinod K Narayana, Laila N Abudulai, Anne-Marie J Shearwood, Henrietta Cserne Szappanos, Dedreia Tull, George C Yeoh, Livia C Hool, Aleksandra Filipovska, Oliver Rackham
Stress signaling and cellular proliferation reverse the effects of mitochondrial mistranslation. The EMBO journal 38 (24) (2019)
Pascal D Vos, Peter J Leedman, Aleksandra Filipovska, Oliver Rackham
Modulation of miRNA function by natural and synthetic RNA-binding proteins in cancer. Cellular and molecular life sciences : CMLS 76 (19) (2019)
Irina Kuznetsova, Artur Lugmayr, Stefan J Siira, Oliver Rackham, Aleksandra Filipovska
CirGO: an alternative circular way of visualising gene ontology terms. BMC bioinformatics 20 (1) (2019)
Jun-Jie Gao, An Qin, Delin Liu, Rui Ruan, Qiyang Wang, Jun Yuan, Tak Sum Cheng, Aleksandra Filipovska, J M Papadimitriou, Kerong Dai, Qing Jiang, Xiang Gao, Jian Q Feng, Hiroshi Takayanagi, Chang-Qing Zhang, Ming-Hao Zheng
Endoplasmic reticulum mediates mitochondrial transfer within the osteocyte dendritic network. Science advances 5 (11) (2019)
Shan Jiang, Camilla Koolmeister, Jelena Misic, Stefan Siira, Inge Kühl, Eduardo Silva Ramos, Maria Miranda, Min Jiang, Viktor Posse, Oleksandr Lytovchenko, Ilian Atanassov, Florian A Schober, Rolf Wibom, Kjell Hultenby, Dusanka Milenkovic, Claes M Gustafsson, Aleksandra Filipovska, Nils-Göran Larsson
TEFM regulates both transcription elongation and RNA processing in mitochondria. EMBO reports 20 (6) (2019)
Danielle L Rudler, Laetitia A Hughes, Kara L Perks, Tara R Richman, Irina Kuznetsova, Judith A Ermer, Laila N Abudulai, Anne-Marie J Shearwood, Helena M Viola, Livia C Hool, Stefan J Siira, Oliver Rackham, Aleksandra Filipovska
Fidelity of translation initiation is required for coordinated respiratory complex assembly. Science advances 5 (12) (2019)
Richard G Lee, Danielle L Rudler, Oliver Rackham, Aleksandra Filipovska
Is mitochondrial gene expression coordinated or stochastic? Biochemical Society transactions 46 (5) (2018)
Stefan J Siira, Giulia Rossetti, Tara R Richman, Kara Perks, Judith A Ermer, Irina Kuznetsova, Laetitia Hughes, Anne-Marie J Shearwood, Helena M Viola, Livia C Hool, Oliver Rackham, Aleksandra Filipovska
Concerted regulation of mitochondrial and nuclear non-coding RNAs by a dual-targeted RNase Z. EMBO reports 19 (10) (2018)
Inge Kühl, Maria Miranda, Ilian Atanassov, Irina Kuznetsova, Yvonne Hinze, Arnaud Mourier, Aleksandra Filipovska, Nils-Göran Larsson
Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals. eLife 6 (2017)
Kara L Perks, Nicola Ferreira, Tara R Richman, Judith A Ermer, Irina Kuznetsova, Anne-Marie J Shearwood, Richard G Lee, Helena M Viola, Victoria P A Johnstone, Vance Matthews, Livia C Hool, Oliver Rackham, Aleksandra Filipovska
Adult-onset obesity is triggered by impaired mitochondrial gene expression. Science advances 3 (8) (2017)

Aleksandra Filipovska.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Aleksandra Filipovska