Owen Richard Davies (Owen R Davies)

ORCID

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 46

Top Venues

Nature structural & molecular biology

Nature communications

EMBO reports

eLife

Newcastle University

University of Cambridge (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Newcastle University Sep 01 2013

United Kingdom

University Research Fellow :: Institute for Cell and Molecular Biosciences

University of Cambridge Jan 01 2010 - Aug 31 2013

United Kingdom

Postdoctoral Research Associate :: Department of Biochemistry

University of Edinburgh Oct 01 2007 - Dec 31 2010

United Kingdom

Royal Commission for 1851 Research Fellow :: Institute for Stem Cell Research

Education History

University of Cambridge

United Kingdom

PHD :: Department of Biochemistry

University of St Andrews

United Kingdom

BSC :: School of Biology

Publications

Manickam Gurusaran, Benedikte S Erlandsen, Owen Richard Davies
The crystal structure of SUN1-KASH6 reveals an asymmetric LINC complex architecture compatible with nuclear membrane insertion. Communications biology 7 (1) (2024)
Manickam Gurusaran, Jingjing Zhang, Kexin Zhang, Hiroki Shibuya, Owen Richard Davies
MEILB2-BRME1 forms a V-shaped DNA clamp upon BRCA2-binding in meiotic recombination. Nature communications 15 (1) (2024)
Reshma Thamkachy, Bethan Medina-Pritchard, Sang Ho Park, Carla G Chiodi, Juan Zou, Maria de la Torre-Barranco, Kazuma Shimanaka, Maria Alba Abad, Cristina Gallego Páramo, Regina Feederle, Emilija Ruksenaite, Patrick Heun, Owen Richard Davies, Juri Rappsilber, Dina Schneidman-Duhovny, Uhn-Soo Cho, Jeyaprakash Arulanandam
Structural basis for Mis18 complex assembly and its implications for centromere maintenance. EMBO reports 25 (8) (2024)
Manickam Gurusaran, Benedikte S Erlandsen, Owen Richard Davies
The crystal structure of SUN1-KASH6 reveals an asymmetric LINC complex architecture compatible with nuclear membrane insertion. Communications biology 7 (1) (2024)
Reshma Thamkachy, Bethan Medina-Pritchard, Sang Ho Park, Carla G Chiodi, Juan Zou, Maria de la Torre-Barranco, Kazuma Shimanaka, Maria Alba Abad, Cristina Gallego Páramo, Regina Feederle, Emilija Ruksenaite, Patrick Heun, Owen Richard Davies, Juri Rappsilber, Dina Schneidman-Duhovny, Uhn-Soo Cho, Jeyaprakash Arulanandam
Structural basis for Mis18 complex assembly and its implications for centromere maintenance. EMBO reports 25 (8) (2024)
Manickam Gurusaran, Jingjing Zhang, Kexin Zhang, Hiroki Shibuya, Owen Richard Davies
MEILB2-BRME1 forms a V-shaped DNA clamp upon BRCA2-binding in meiotic recombination. Nature communications 15 (1) (2024)
Reshma Thamkachy, Bethan Medina-Pritchard, Sang Ho Park, Carla G Chiodi, Juan Zou, Maria de la Torre-Barranco, Kazuma Shimanaka, Maria Alba Abad, Cristina Gallego Páramo, Regina Feederle, Emilija Ruksenaite, Patrick Heun, Owen Richard Davies, Juri Rappsilber, Dina Schneidman-Duhovny, Uhn-Soo Cho, Jeyaprakash Arulanandam
Structural basis for Mis18 complex assembly and its implications for centromere maintenance. EMBO reports (2024)
Reshma Thamkachy, Bethan Medina-Pritchard, Sang Ho Park, Carla G Chiodi, Juan Zou, Maria de la Torre-Barranco, Kazuma Shimanaka, Maria Alba Abad, Cristina Gallego Páramo, Regina Feederle, Emilija Ruksenaite, Patrick Heun, Owen Richard Davies, Juri Rappsilber, Dina Schneidman-Duhovny, Uhn-Soo Cho, Jeyaprakash Arulanandam
Structural basis for Mis18 complex assembly and its implications for centromere maintenance. EMBO reports 25 (8) (2024)
Manickam Gurusaran, Benedikte S Erlandsen, Owen Richard Davies
The crystal structure of SUN1-KASH6 reveals an asymmetric LINC complex architecture compatible with nuclear membrane insertion. Communications biology 7 (1) (2024)
Reshma Thamkachy, Bethan Medina-Pritchard, Sang Ho Park, Carla G Chiodi, Juan Zou, Maria de la Torre-Barranco, Kazuma Shimanaka, Maria Alba Abad, Cristina Gallego Páramo, Regina Feederle, Emilija Ruksenaite, Patrick Heun, Owen Richard Davies, Juri Rappsilber, Dina Schneidman-Duhovny, Uhn-Soo Cho, Jeyaprakash Arulanandam
Structural basis for Mis18 complex assembly and its implications for centromere maintenance. EMBO reports 25 (8) (2024)
Manickam Gurusaran, Jingjing Zhang, Kexin Zhang, Hiroki Shibuya, Owen Richard Davies
MEILB2-BRME1 forms a V-shaped DNA clamp upon BRCA2-binding in meiotic recombination. Nature communications 15 (1) (2024)
Kirsten E L Garner, Anna Salter, Clinton K Lau, Manickam Gurusaran, Cécile M Villemant, Elizabeth P Granger, Gavin McNee, Philip G Woodman, Owen Richard Davies, Brian E Burke, Victoria J Allan
The meiotic LINC complex component KASH5 is an activating adaptor for cytoplasmic dynein. The Journal of cell biology 222 (5) (2023)
James H Crichton, James M Dunce, Orla M Dunne, Lucy J Salmon, Paul S Devenney, Jennifer Lawson, Ian R Adams, Owen Richard Davies
Structural maturation of SYCP1-mediated meiotic chromosome synapsis by SYCE3. Nature structural & molecular biology 30 (2) (2023)
James H Crichton, James M Dunce, Orla M Dunne, Lucy J Salmon, Paul S Devenney, Jennifer Lawson, Ian R Adams, Owen Richard Davies
Structural maturation of SYCP1-mediated meiotic chromosome synapsis by SYCE3. Nature structural & molecular biology 30 (2) (2023)
James H Crichton, James M Dunce, Orla M Dunne, Lucy J Salmon, Paul S Devenney, Jennifer Lawson, Ian R Adams, Owen Richard Davies
Structural maturation of SYCP1-mediated meiotic chromosome synapsis by SYCE3. Nature structural & molecular biology 30 (2) (2023)
James H Crichton, James M Dunce, Orla M Dunne, Lucy J Salmon, Paul S Devenney, Jennifer Lawson, Ian R Adams, Owen Richard Davies
Structural maturation of SYCP1-mediated meiotic chromosome synapsis by SYCE3. Nature structural & molecular biology 30 (2) (2023)
Kirsten E L Garner, Anna Salter, Clinton K Lau, Manickam Gurusaran, Cécile M Villemant, Elizabeth P Granger, Gavin McNee, Philip G Woodman, Owen Richard Davies, Brian E Burke, Victoria J Allan
The meiotic LINC complex component KASH5 is an activating adaptor for cytoplasmic dynein. The Journal of cell biology 222 (5) (2023)
James H Crichton, James M Dunce, Orla M Dunne, Lucy J Salmon, Paul S Devenney, Jennifer Lawson, Ian R Adams, Owen Richard Davies
Structural maturation of SYCP1-mediated meiotic chromosome synapsis by SYCE3. Nature structural & molecular biology 30 (2) (2023)
Katherine Kretovich Billmyre, Emily A Kesler, Dai Tsuchiya, Timothy J Corbin, Kyle Weaver, Andrea Moran, Zulin Yu, Lane Adams, Kym Delventhal, Michael Durnin, Owen Richard Davies, R Scott Hawley
SYCP1 head-to-head assembly is required for chromosome synapsis in mouse meiosis. Science advances 9 (42) (2023)
Kirsten E L Garner, Anna Salter, Clinton K Lau, Manickam Gurusaran, Cécile M Villemant, Elizabeth P Granger, Gavin McNee, Philip G Woodman, Owen Richard Davies, Brian E Burke, Victoria J Allan
The meiotic LINC complex component KASH5 is an activating adaptor for cytoplasmic dynein. The Journal of cell biology 222 (5) (2023)
Leila Tamara Alexander, Janani Durairaj, Andriy Kryshtafovych, Luciano Andrés Abriata, Yusupha Bayo, Gira Bhabha, Cécile Breyton, Simon G Caulton, James Chen, Séraphine Degroux, Damian C Ekiert, Benedikte S Erlandsen, Peter L Freddolino, Dominic Gilzer, Chris Greening, Jonathan M Grimes, Rhys W Grinter, Manickam Gurusaran, Marcus D Hartmann, Charlie J Hitchman, Jeremy Russell Keown, Ashleigh Kropp, Petri Kursula, Andrew Lee Lovering, Bruno Lemaître, Andrea Lia, Shiheng Liu, Maria Logotheti, Shuze Lu, Sigurbjörn Markússon, Mitchell D Miller, George Minasov, Hartmut H Niemann, Felipe Opazo, George N Philips, Owen Richard Davies, Samuel Rommelaere, Monica Rosas-Lemus, Pietro Roversi, Karla J F Satchell, Nathan Smith, Mark A Wilson, Kuan-Lin Wu, Xian Xia, Han Xiao, Wenhua Zhang, Z Hong Zhou, Krzysztof Fidelis, Andriy Kryshtafovych, John Moult, Torsten Schwede
Protein target highlights in CASP15: Analysis of models by structure providers. Proteins (2023)
James H Crichton, James M Dunce, Orla M Dunne, Lucy J Salmon, Paul S Devenney, Jennifer Lawson, Ian R Adams, Owen Richard Davies
Structural maturation of SYCP1-mediated meiotic chromosome synapsis by SYCE3. Nature structural & molecular biology 30 (2) (2023)
James H Crichton, James M Dunce, Orla M Dunne, Lucy J Salmon, Paul S Devenney, Jennifer Lawson, Ian R Adams, Owen Richard Davies
Structural maturation of SYCP1-mediated meiotic chromosome synapsis by SYCE3. Nature structural & molecular biology (2023)
James H Crichton, James M Dunce, Orla M Dunne, Lucy J Salmon, Paul S Devenney, Jennifer Lawson, Ian R Adams, Owen Richard Davies
Structural maturation of SYCP1-mediated meiotic chromosome synapsis by SYCE3. Nature structural & molecular biology 30 (2) (2023)
James H Crichton, James M Dunce, Orla M Dunne, Lucy J Salmon, Paul S Devenney, Jennifer Lawson, Ian R Adams, Owen Richard Davies
Structural maturation of SYCP1-mediated meiotic chromosome synapsis by SYCE3. Nature structural & molecular biology (2023)
James H Crichton, James M Dunce, Orla M Dunne, Lucy J Salmon, Paul S Devenney, Jennifer Lawson, Ian R Adams, Owen Richard Davies
Structural maturation of SYCP1-mediated meiotic chromosome synapsis by SYCE3. Nature structural & molecular biology 30 (2) (2023)
James H Crichton, James M Dunce, Orla M Dunne, Lucy J Salmon, Paul S Devenney, Jennifer Lawson, Ian R Adams, Owen Richard Davies
Structural maturation of SYCP1-mediated meiotic chromosome synapsis by SYCE3. Nature structural & molecular biology 30 (2) (2023)
James H Crichton, James M Dunce, Orla M Dunne, Lucy J Salmon, Paul S Devenney, Jennifer Lawson, Ian R Adams, Owen Richard Davies
Structural maturation of SYCP1-mediated meiotic chromosome synapsis by SYCE3. Nature structural & molecular biology 30 (2) (2023)
James M Dunce, Lucy J Salmon, Owen Richard Davies
Coiled-coil structure of meiosis protein TEX12 and conformational regulation by its C-terminal tip. Communications biology 5 (1) (2022)
Sumit Sandhu, Ieng F Sou, Jill E Hunter, Lucy Salmon, Caroline L Wilson, Neil D Perkins, Neil Hunter, Owen Richard Davies, Urszula Lucja McClurg
Centrosome dysfunction associated with somatic expression of the synaptonemal complex protein TEX12. Communications biology 4 (1) (2021)
Nikhil R Bhagwat, Shannon N Owens, Masaru Ito, Jay V Boinapalli, Philip Poa, Alexander Ditzel, Srujan Kopparapu, Meghan Mahalawat, Owen Richard Davies, Sean R Collins, Jeffrey R Johnson, Nevan J Krogan, Neil Hunter
SUMO is a pervasive regulator of meiosis. eLife 10 (2021)
Christopher Thomas, Benjamin Wetherall, Mark D Levasseur, Rebecca J Harris, Scott T Kerridge, Jonathan M G Higgins, Owen Richard Davies, Suzanne Madgwick
A prometaphase mechanism of securin destruction is essential for meiotic progression in mouse oocytes. Nature communications 12 (1) (2021)
James M Dunce, Lucy J Salmon, Owen Richard Davies
Structural basis of meiotic chromosome synaptic elongation through hierarchical fibrous assembly of SYCE2-TEX12. Nature structural & molecular biology 28 (8) (2021)
Manickam Gurusaran, Owen Richard Davies
A molecular mechanism for LINC complex branching by structurally diverse SUN-KASH 6:6 assemblies. eLife 10 (2021)
Jens M H Thomas, Ronan M Keegan, Daniel J Rigden, Owen Richard Davies
Extending the scope of coiled-coil crystal structure solution by AMPLE through improved ab initio modelling. Acta crystallographica. Section D, Structural biology 76 (Pt 3) (2020)
Filomeno Sánchez Rodríguez, Adam J Simpkin, Owen Richard Davies, Ronan M Keegan, Daniel J Rigden
Helical ensembles outperform ideal helices in molecular replacement. Acta crystallographica. Section D, Structural biology 76 (Pt 10) (2020)
Fernando Sánchez-Sáez, Laura Gómez-H, Orla M Dunne, Cristina Gallego-Páramo, Natalia Felipe-Medina, Manuel A Sanchez-Martin, Elena Llano, Alberto M Pendas, Owen Richard Davies
Meiotic chromosome synapsis depends on multivalent SYCE1-SIX6OS1 interactions that are disrupted in cases of human infertility. Science advances 6 (36) (2020)
Jingjing Zhang, Manickam Gurusaran, Yasuhiro Fujiwara, Kexin Zhang, Meriem Echbarthi, Egor Vorontsov, Rui Guo, Devon F Pendlebury, Intekhab Alam, Gabriel Livera, Martini Emmanuelle, P Jeremy Wang, Jayakrishnan Nandakumar, Owen Richard Davies, Hiroki Shibuya
The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells. Nature communications 11 (1) (2020)
Bernadette Carroll, Dorothea Maetzel, Oliver Dk Maddocks, Gisela Otten, Matthew Ratcliff, Graham R Smith, Elaine A Dunlop, João F Passos, Owen Richard Davies, Rudolf Jaenisch, Andrew R Tee, Sovan Sarkar, Viktor I Korolchuk
Correction: Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity. eLife 9 (2020)
Orla M Dunne, Owen Richard Davies
Molecular structure of human synaptonemal complex protein SYCE1. Chromosoma 128 (3) (2019)
Orla M Dunne, Owen Richard Davies
A molecular model for self-assembly of the synaptonemal complex protein SYCE3. The Journal of biological chemistry 294 (23) (2019)
Karen Voelkel-Meiman, Shun-Yun Cheng, Melanie P Parziale, Savannah J Morehouse, Arden Feil, Owen Richard Davies, Arnaud de Muyt, Valérie Borde, Amy J MacQueen
Crossover recombination and synapsis are linked by adjacent regions within the N terminus of the Zip1 synaptonemal complex protein. PLoS genetics 15 (6) (2019)
James M Dunce, Amy E Milburn, Manickam Gurusaran, Irene da Cruz, Lee T Sen, Ricardo Benavente, Owen Richard Davies
Structural basis of meiotic telomere attachment to the nuclear envelope by MAJIN-TERB2-TERB1. Nature communications 9 (1) (2018)
James M Dunce, Orla M Dunne, Matthew Ratcliff, Claudia Millán, Suzanne Madgwick, Isabel Usón, Owen Richard Davies
Structural basis of meiotic chromosome synapsis through SYCP1 self-assembly. Nature structural & molecular biology 25 (7) (2018)
Johanna L Syrjänen, Iddo Heller, Andrea Candelli, Owen Richard Davies, Erwin J G Peterman, Gijs J L Wuite, Luca Pellegrini
Single-molecule observation of DNA compaction by meiotic protein SYCP3. eLife 6 (2017)
Laura Gómez-H, Natalia Felipe-Medina, Manuel Sánchez-Martín, Owen Richard Davies, Isabel Ramos, Ignacio García-Tuñón, Dirk G de Rooij, Ihsan Dereli, Attila Tóth, José Luis Barbero, Ricardo Benavente, Elena Llano, Alberto M Pendas
C14ORF39/SIX6OS1 is a constituent of the synaptonemal complex and is essential for mouse fertility. Nature communications 7 (2016)
Johanna Liinamaria Syrjänen, Luca Pellegrini, Owen Richard Davies
A molecular model for the role of SYCP3 in meiotic chromosome organisation. eLife 3 (2014)

Owen Richard Davies.css-eqlu8i{font-size:small;padding-left:4px;} (Owen R Davies)

Publication Activity (10 Years)

Top Topics

Top Venues

Owen Richard Davies (Owen R Davies)