James Chen

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 14

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Nature structural & molecular biology

Research square

The EMBO journal

The Rockefeller University

Rockefeller University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

The Rockefeller University Jul 01 2020

United States

Postdoctoral Associate :: Laboratory of Molecular Biophysics

Education History

Rockefeller University Sep 03 2013 - Jun 11 2020

United States

PHD

Publications

Ruth M Saecker, Andreas U Mueller, Brandon Malone, James Chen, William C Budell, Venkata P Dandey, Kashyap Maruthi, Joshua H Mendez, Nina Molina, Edward T Eng, Laura Y Yen, Clinton S Potter, Bridget Carragher, Seth A Darst
Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy. Nature structural & molecular biology (2024)
Ruth M Saecker, Andreas U Mueller, Brandon Malone, James Chen, William C Budell, Venkata P Dandey, Kashyap Maruthi, Joshua H Mendez, Nina Molina, Edward T Eng, Laura Y Yen, Clinton S Potter, Bridget Carragher, Seth A Darst
Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy. Nature structural & molecular biology (2024)
Andreas U Mueller, James Chen, Mengyu Wu, Courtney Chiu, B Tracy Nixon, Elizabeth A Campbell, Seth A Darst
A general mechanism for transcription bubble nucleation in bacteria. Proceedings of the National Academy of Sciences of the United States of America 120 (14) (2023)
James Chen, Alice Fruhauf, Catherine Fan, Jackeline Ponce, Beatrix Ueberheide, Gira Bhabha, Damian C Ekiert
Structure of an endogenous mycobacterial MCE lipid transporter. Research square (2023)
Andreas U Mueller, James Chen, Mengyu Wu, Courtney Chiu, B Tracy Nixon, Elizabeth A Campbell, Seth A Darst
A general mechanism for transcription bubble nucleation in bacteria. Proceedings of the National Academy of Sciences of the United States of America 120 (14) (2023)
Leila Tamara Alexander, Janani Durairaj, Andriy Kryshtafovych, Luciano Andrés Abriata, Yusupha Bayo, Gira Bhabha, Cécile Breyton, Simon G Caulton, James Chen, Séraphine Degroux, Damian C Ekiert, Benedikte S Erlandsen, Peter L Freddolino, Dominic Gilzer, Chris Greening, Jonathan M Grimes, Rhys W Grinter, Manickam Gurusaran, Marcus D Hartmann, Charlie J Hitchman, Jeremy Russell Keown, Ashleigh Kropp, Petri Kursula, Andrew Lee Lovering, Bruno Lemaître, Andrea Lia, Shiheng Liu, Maria Logotheti, Shuze Lu, Sigurbjörn Markússon, Mitchell D Miller, George Minasov, Hartmut H Niemann, Felipe Opazo, George N Philips, Owen Richard Davies, Samuel Rommelaere, Monica Rosas-Lemus, Pietro Roversi, Karla J F Satchell, Nathan Smith, Mark A Wilson, Kuan-Lin Wu, Xian Xia, Han Xiao, Wenhua Zhang, Z Hong Zhou, Krzysztof Fidelis, Andriy Kryshtafovych, John Moult, Torsten Schwede
Protein target highlights in CASP15: Analysis of models by structure providers. Proteins (2023)
James Chen, Damian C Ekiert
A tale of two inhibitors: diarylquinolines and squaramides. The EMBO journal (2023)
James Chen, Alice Fruhauf, Catherine Fan, Jackeline Ponce, Beatrix Ueberheide, Gira Bhabha, Damian C Ekiert
Structure of an endogenous mycobacterial MCE lipid transporter. Research square (2023)
James Chen, Alice Fruhauf, Catherine Fan, Jackeline Ponce, Beatrix Ueberheide, Gira Bhabha, Damian C Ekiert
Structure of an endogenous mycobacterial MCE lipid transporter. Nature (2023)
James Chen, Qi Wang, Brandon F Malone, Eliza Llewellyn, Yakov Pechersky, Kashyap Maruthi, Edward T Eng, Jason K Perry, Elizabeth A Campbell, David E Shaw, Seth A Darst
Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex. Nature structural & molecular biology 29 (3) (2022)
Brandon F Malone, James Chen, Qi Wang, Eliza Llewellyn, Young Joo Choi, Paul Dominic B Olinares, Xinyun Cao, Carolina Hernandez, Edward T Eng, Brian T Chait, David E Shaw, Robert Landick, Seth A Darst, Elizabeth A Campbell
Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex. Proceedings of the National Academy of Sciences of the United States of America 118 (19) (2021)
James Chen, Hande Boyaci, Elizabeth A Campbell
Diverse and unified mechanisms of transcription initiation in bacteria. Nature reviews. Microbiology 19 (2) (2020)
Mirjana Lilic, James Chen, Hande Boyaci, Nathaniel R Braffman, Elizabeth A Hubin, Jennifer Herrmann, Daniel Krug, Rachel Mooney, Robert Landick, Seth A Darst, Elizabeth A Campbell
The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase. Proceedings of the National Academy of Sciences of the United States of America 117 (48) (2020)
James Chen, Saumya Gopalkrishnan, Courtney Chiu, Albert Y Chen, Elizabeth A Campbell, Richard L Gourse, Wilma Ross, Seth A Darst
E. coli TraR allosterically regulates transcription initiation by altering RNA polymerase conformation. eLife 8 (2019)

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Publication Activity (10 Years)

Top Topics

Top Venues

James Chen