Margaret A Brimble (M A Brimble, Margaret Brimble)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 134

Top Venues

Organic & biomolecular chemistry

Organic letters

Angewandte Chemie (International ed. in English)

Journal of natural products

University of Auckland

University of Southampton (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Auckland

New Zealand

Distinguished Professor :: Chemistry

Maurice Wilkins Centre

New Zealand

Principal Investigator; Member Management Committee :: Chemistry

University of Auckland

New Zealand

Professor and Chair of Organic Chemistry; Director of Medicinal Chemistry :: Chemistry

University of Auckland

New Zealand

Medicinal Chemistry Consultant :: Chemistry

University of Sydney

Australia

Reader/Associate Professor Organic Chemistry :: Chemistry

University of Sydney

Australia

Senior Lecturer in Organic Chemistry :: Chemistry

University of Auckland

New Zealand

Senior Lecturer in Chemistry :: Chemistry

University of California Berkeley

United States

Invited Visiting Professor :: Chemistry

Massey University

New Zealand

Lecturer in Chemistry :: Chemistry

Education History

University of Southampton

United Kingdom

PHD :: Chemistry

University of Auckland

New Zealand

BSC :: Chemistry

Publications

Patrick L Cahill, Lindon W K Moodie, Cora Hertzer, Emiliano Pinori, Henrik Pavia, Claire Hellio, Margaret A Brimble, Johan Svenson
Creating New Antifoulants Using the Tools and Tactics of Medicinal Chemistry. Accounts of chemical research 57 (3) (2024)
Patrick L Cahill, Lindon W K Moodie, Cora Hertzer, Emiliano Pinori, Henrik Pavia, Claire Hellio, Margaret A Brimble, Johan Svenson
Creating New Antifoulants Using the Tools and Tactics of Medicinal Chemistry. Accounts of chemical research 57 (3) (2024)
Oscar A Shepperson, Paul W R Harris, Margaret A Brimble, Alan J Cameron
The Antimicrobial Peptide Capitellacin: Chemical Synthesis of Analogues to Probe the Role of Disulphide Bridges and Their Replacement with Vinyl Sulphides. Antibiotics (Basel, Switzerland) 13 (7) (2024)
Grace J Drummond, Phillip S Grant, Alisha M Geurts, Daniel P Furkert, Margaret A Brimble
Synthesis of the bicyclic butenolide core of pallamolide A: a biomimetic approach. Organic & biomolecular chemistry (2024)
Fabio Fusi, Simona Saponara, Margaret A Brimble, David Rennison, Brian Hopkins, Sergio Bova
The Enigma of Norbormide, a Rattus -Selective Toxicant. Cells 13 (9) (2024)
Tae-Ung Na, Veronika Sander, Alan J Davidson, Rolland Lin, Yann O Hermant, Madeleine T Hardie Boys, Daniel Pletzer, Georgia Campbell, Scott A Ferguson, Gregory M Cook, Jane R Allison, Margaret A Brimble, Brian H Northrop, Alan J Cameron
Allenamides as a Powerful Tool to Incorporate Diversity: Thia-Michael Lipidation of Semisynthetic Peptides and Access to β-Keto Amides. Angewandte Chemie (International ed. in English) (2024)
Patrick L Cahill, Lindon W K Moodie, Cora Hertzer, Emiliano Pinori, Henrik Pavia, Claire Hellio, Margaret A Brimble, Johan Svenson
Creating New Antifoulants Using the Tools and Tactics of Medicinal Chemistry. Accounts of chemical research 57 (3) (2024)
Dennise Palpal-Latoc, Aimee J Horsfall, Alan J Cameron, Georgia Campbell, Scott A Ferguson, Gregory M Cook, Veronika Sander, Alan J Davidson, Paul W R Harris, Margaret A Brimble
Synthesis, Structure-Activity Relationship Study, Bioactivity, and Nephrotoxicity Evaluation of the Proposed Structure of the Cyclic Lipodepsipeptide Brevicidine B. Journal of natural products (2024)
Patrick L Cahill, Lindon W K Moodie, Cora Hertzer, Emiliano Pinori, Henrik Pavia, Claire Hellio, Margaret A Brimble, Johan Svenson
Creating New Antifoulants Using the Tools and Tactics of Medicinal Chemistry. Accounts of chemical research (2024)
Dennise Palpal-Latoc, Aimee J Horsfall, Alan J Cameron, Georgia Campbell, Scott A Ferguson, Gregory M Cook, Veronika Sander, Alan J Davidson, Paul W R Harris, Margaret A Brimble
Synthesis, Structure-Activity Relationship Study, Bioactivity, and Nephrotoxicity Evaluation of the Proposed Structure of the Cyclic Lipodepsipeptide Brevicidine B. Journal of natural products 87 (4) (2024)
Fabio Fusi, Simona Saponara, Margaret A Brimble, David Rennison, Brian Hopkins, Sergio Bova
The Enigma of Norbormide, a Rattus -Selective Toxicant. Cells 13 (9) (2024)
Marzieh Ahangarpour, Margaret A Brimble, Iman Kavianinia
Late-Stage Desulfurization Enables Rapid and Efficient Solid-Phase Synthesis of Cathepsin-Cleavable Linkers for Antibody-Drug Conjugates. Bioconjugate chemistry (2024)
Cara Adolph, Kiel Hards, Zoe C Williams, Chen-Yi Cheung, Laura M Keighley, William J Jowsey, Matson Kyte, Daniel Ken Inaoka, Kiyoshi Kita, Jared S Mackenzie, Adrie J C Steyn, Zhengqiu Li, Ming Yan, Guo-Bao Tian, Tian-Yu Zhang, Xiaobo Ding, Daniel P Furkert, Margaret A Brimble, Anthony J R Hickey, Matthew B McNeil, Gregory M Cook
Identification of Chemical Scaffolds That Inhibit the Mycobacterium tuberculosis Respiratory Complex Succinate Dehydrogenase. ACS infectious diseases (2024)
Oscar A Shepperson, Paul W R Harris, Margaret A Brimble, Alan J Cameron
The Antimicrobial Peptide Capitellacin: Chemical Synthesis of Analogues to Probe the Role of Disulphide Bridges and Their Replacement with Vinyl Sulphides. Antibiotics (Basel, Switzerland) 13 (7) (2024)
Marzieh Ahangarpour, Margaret A Brimble, Iman Kavianinia
Late-Stage Desulfurization Enables Rapid and Efficient Solid-Phase Synthesis of Cathepsin-Cleavable Linkers for Antibody-Drug Conjugates. Bioconjugate chemistry 35 (7) (2024)
Dennise Palpal-Latoc, Aimee J Horsfall, Alan J Cameron, Georgia Campbell, Scott A Ferguson, Gregory M Cook, Veronika Sander, Alan J Davidson, Paul W R Harris, Margaret A Brimble
Synthesis, Structure-Activity Relationship Study, Bioactivity, and Nephrotoxicity Evaluation of the Proposed Structure of the Cyclic Lipodepsipeptide Brevicidine B. Journal of natural products 87 (4) (2024)
Oscar A Shepperson, Paul W R Harris, Margaret A Brimble, Alan J Cameron
The Antimicrobial Peptide Capitellacin: Chemical Synthesis of Analogues to Probe the Role of Disulphide Bridges and Their Replacement with Vinyl Sulphides. Antibiotics (Basel, Switzerland) 13 (7) (2024)
Juliana T W Tong, Makhdoom Sarwar, Marzieh Ahangarpour, Paul A Hume, Geoffrey M Williams, Margaret A Brimble, Iman Kavianinia
Use of a Cyclic α-Alkylidene-β-Diketone as a Cleavable Linker Strategy for Antibody-Drug Conjugates. Journal of the American Chemical Society (2024)
Juliana T W Tong, Makhdoom Sarwar, Marzieh Ahangarpour, Paul A Hume, Geoffrey M Williams, Margaret A Brimble, Iman Kavianinia
Use of a Cyclic α-Alkylidene-β-Diketone as a Cleavable Linker Strategy for Antibody-Drug Conjugates. Journal of the American Chemical Society 146 (34) (2024)
Marzieh Ahangarpour, Margaret A Brimble, Iman Kavianinia
Late-Stage Desulfurization Enables Rapid and Efficient Solid-Phase Synthesis of Cathepsin-Cleavable Linkers for Antibody-Drug Conjugates. Bioconjugate chemistry 35 (7) (2024)
Fabio Fusi, Simona Saponara, Margaret A Brimble, David Rennison, Brian Hopkins, Sergio Bova
The Enigma of Norbormide, a Rattus -Selective Toxicant. Cells 13 (9) (2024)
Shengping Zhang, Luis M De Leon Rodriguez, Freda F Li, Margaret A Brimble
Recent developments in the cleavage, functionalization, and conjugation of proteins and peptides at tyrosine residues. Chemical science 14 (29) (2023)
Andrew D W Earl, Freda F Li, Chao Ma, Daniel P Furkert, Margaret A Brimble
Stereoselective synthesis of the spirocyclic core of 13-desmethyl spirolide C using an aza-Claisen rearrangement and an exo -selective Diels-Alder cycloaddition. Organic & biomolecular chemistry 21 (6) (2023)
Andrew D W Earl, Freda F Li, Chao Ma, Daniel P Furkert, Margaret A Brimble
Stereoselective synthesis of the spirocyclic core of 13-desmethyl spirolide C using an aza-Claisen rearrangement and an exo -selective Diels-Alder cycloaddition. Organic & biomolecular chemistry (2023)
Shama Dissanayake, Junming He, Sung H Yang, Margaret A Brimble, Paul W R Harris, Alan J Cameron
Flow-Based Fmoc-SPPS Preparation and SAR Study of Cathelicidin-PY Reveals Selective Antimicrobial Activity. Molecules (Basel, Switzerland) 28 (4) (2023)
Elena Harjes, Patrick J B Edwards, Sean W Bisset, Mark L Patchett, Geoffrey B Jameson, Sung-Hyun Yang, Claudio D Navo, Paul W R Harris, Margaret A Brimble, Gillian E Norris
NMR Shows Why a Small Chemical Change Almost Abolishes the Antimicrobial Activity of Glycocin F. Biochemistry (2023)
Johanes K Kasim, Jiwon Hong, Anthony J R Hickey, Anthony Ronald John Phillips, John A Windsor, Paul W R Harris, Margaret A Brimble, Iman Kavianinia
The Anti-Tubercular Aminolipopeptide Trichoderin A Displays Selective Toxicity against Human Pancreatic Ductal Adenocarcinoma Cells Cultured under Glucose Starvation. Pharmaceutics 15 (1) (2023)
Alexander J Craig, Yuri Ermolovich, Alan Cameron, Agnes Rodler, Helen Wang, Jeffrey A Hawkes, Madlen Hubert, Fredrik Björkling, Natalia Molchanova, Margaret A Brimble, Lindon W K Moodie, Johan Svenson
Antimicrobial Peptides Incorporating Halogenated Marine-Derived Amino Acid Substituents. ACS medicinal chemistry letters 14 (6) (2023)
Patrick L Cahill, Thomas M Grant, David Rennison, Olivier Champeau, Michael J Boundy, Emillie M F Passfield, Mattias Berglin, Margaret A Brimble, Johan Svenson
Nature-Inspired Peptide Antifouling Biocide: Coating Compatibility, Field Validation, and Environmental Stability. ACS applied bio materials (2023)
Shama Dissanayake, Junming He, Sung H Yang, Margaret A Brimble, Paul W R Harris, Alan J Cameron
Flow-Based Fmoc-SPPS Preparation and SAR Study of Cathelicidin-PY Reveals Selective Antimicrobial Activity. Molecules (Basel, Switzerland) 28 (4) (2023)
Shama Dissanayake, Junming He, Sung H Yang, Margaret A Brimble, Paul W R Harris, Alan J Cameron
Flow-Based Fmoc-SPPS Preparation and SAR Study of Cathelicidin-PY Reveals Selective Antimicrobial Activity. Molecules (Basel, Switzerland) 28 (4) (2023)
Louise A Stubbing, Jonathan G Hubert, Joseph Bell-Tyrer, Yann O Hermant, Sung Hyun Yang, Alice M McSweeney, Geena M McKenzie-Goldsmith, Vernon K Ward, Daniel P Furkert, Margaret A Brimble
P 1 Glutamine isosteres in the design of inhibitors of 3C/3CL protease of human viruses of the Pisoniviricetes class. RSC chemical biology 4 (8) (2023)
Andrew D W Earl, Freda F Li, Chao Ma, Daniel P Furkert, Margaret A Brimble
Stereoselective synthesis of the spirocyclic core of 13-desmethyl spirolide C using an aza-Claisen rearrangement and an exo -selective Diels-Alder cycloaddition. Organic & biomolecular chemistry 21 (6) (2023)
Xiao-Bo Ding, Alexander Wung, Daniel P Furkert, Margaret A Brimble
Synthesis of the spiroimine fragment of portimines A and B. Organic & biomolecular chemistry (2023)
Bin Lin, Smitha Nair, Daniel M J Fellner, Noha Ahmed Nasef, Harjinder Singh, Leonardo Negron, David C Goldstone, Margaret A Brimble, Juliet A Gerrard, Laura Domigan, Jackie C Evans, Jonathan M Stephens, Troy L Merry, Kerry M Loomes
The Leptospermum scoparium (Mānuka)-Specific Nectar and Honey Compound 3,6,7-Trimethyllumazine (Lepteridine TM ) That Inhibits Matrix Metalloproteinase 9 (MMP-9) Activity. Foods (Basel, Switzerland) 12 (22) (2023)
Joseph J Bell-Tyrer, Paul A Hume, Phillip S Grant, Margaret A Brimble, Daniel P Furkert
Azide-Enolate Cycloaddition-Rearrangement Enables Direct α-Amination of Amides and Enelactam Synthesis from Esters. Chemistry (Weinheim an der Bergstrasse, Germany) (2023)
Johanes K Kasim, Jiwon Hong, Anthony J R Hickey, Anthony Ronald John Phillips, John A Windsor, Paul W R Harris, Margaret A Brimble, Iman Kavianinia
The Anti-Tubercular Aminolipopeptide Trichoderin A Displays Selective Toxicity against Human Pancreatic Ductal Adenocarcinoma Cells Cultured under Glucose Starvation. Pharmaceutics 15 (1) (2023)
Saawan Kumar, Mie Riisom, Stephen M F Jamieson, Iman Kavianinia, Paul W R Harris, Nils Metzler Nolte, Margaret A Brimble, Christian G Hartinger
On-Resin Conjugation of the Ruthenium Anticancer Agent Plecstatin-1 to Peptide Vectors. Inorganic chemistry (2023)
C H Andy Wong, Jonathan G Hubert, Kevin J Sparrow, Lawrence D Harris, Peter C Tyler, Margaret A Brimble
Expedient synthesis of imino-C-nucleoside fleximers featuring a one-pot procedure to prepare aryl triazoles. Organic & biomolecular chemistry (2023)
Dennise Palpal-Latoc, Margaret A Brimble, Paul W R Harris, Aimee J Horsfall
Factors influencing on-resin depsipeptide bond formation: case studies on daptomycin- and brevicidine-derived sequences. Organic & biomolecular chemistry (2023)
Alice-Roza Eruera, Alice M McSweeney, Geena M McKenzie-Goldsmith, Helen K Opel-Reading, Simone X Thomas, Ashley C Campbell, Louise Stubbing, Andrew Siow, Jonathan G Hubert, Margaret A Brimble, Vernon K Ward, Kurt L Krause
Crystal Structure of Inhibitor-Bound GII.4 Sydney 2012 Norovirus 3C-Like Protease. Viruses 15 (11) (2023)
Johanes K Kasim, Jiwon Hong, Anthony J R Hickey, Anthony Ronald John Phillips, John A Windsor, Paul W R Harris, Margaret A Brimble, Iman Kavianinia
The Anti-Tubercular Aminolipopeptide Trichoderin A Displays Selective Toxicity against Human Pancreatic Ductal Adenocarcinoma Cells Cultured under Glucose Starvation. Pharmaceutics 15 (1) (2023)
Eilidh G Young, Phillip S Grant, Daniel P Furkert, Margaret A Brimble
Total Synthesis of Spiroketal Alkaloids Lycibarbarines A-C. Organic letters (2023)
Johanes K Kasim, Jiwon Hong, Anthony J R Hickey, Anthony Ronald John Phillips, John A Windsor, Paul W R Harris, Margaret A Brimble, Iman Kavianinia
The Anti-Tubercular Aminolipopeptide Trichoderin A Displays Selective Toxicity against Human Pancreatic Ductal Adenocarcinoma Cells Cultured under Glucose Starvation. Pharmaceutics 15 (1) (2023)
Clouie Justin Aguilar, Makhdoom Sarwar, Sujay Prabakar, Wenkai Zhang, Paul W R Harris, Margaret A Brimble, Iman Kavianinia
Harnessing the power of a photoinitiated thiol-ene "click" reaction for the efficient synthesis of S -lipidated collagen model peptide amphiphiles. Organic & biomolecular chemistry (2023)
Marzieh Ahangarpour, Iman Kavianinia, Margaret A Brimble
Thia-Michael addition: the route to promising opportunities for fast and cysteine-specific modification. Organic & biomolecular chemistry (2023)
Margaret A Brimble, Harry L Anderson, Yan-Mei Li, Monika Raj
Chemoselective Methods for Labeling and Modification of Peptides and Proteins. Organic letters 25 (36) (2023)
Andrew D W Earl, Freda F Li, Chao Ma, Daniel P Furkert, Margaret A Brimble
Stereoselective synthesis of the spirocyclic core of 13-desmethyl spirolide C using an aza-Claisen rearrangement and an exo -selective Diels-Alder cycloaddition. Organic & biomolecular chemistry 21 (6) (2023)
Thomas M Grant, David Rennison, Alexandra L Krause, Sonya Mros, Scott A Ferguson, Gregory M Cook, Alan Cameron, Homayon J Arabshahi, Margaret A Brimble, Patrick L Cahill, Johan Svenson
Stereochemical Effects on the Antimicrobial Properties of Tetrasubstituted 2,5-Diketopiperazines. ACS medicinal chemistry letters 13 (4) (2022)
Tyla I Alexander, Zoe Tasma, Andrew Siow, Tayla A Rees, Margaret A Brimble, Paul W R Harris, Debbie L Hay, Christopher S Walker
Novel Fluorescently Labeled PACAP and VIP Highlight Differences between Peptide Internalization and Receptor Pharmacology. ACS pharmacology & translational science 6 (1) (2022)
Aakanksha Rani, Luis M De Leon Rodriguez, Iman Kavianinia, Duncan J McGillivray, David E Williams, Margaret A Brimble
Synthesis and characterization of mono S-lipidated peptide hydrogels: a platform for the preparation of reactive oxygen species responsive materials. Organic & biomolecular chemistry 19 (16) (2022)
Shengping Zhang, Luis M De Leon Rodriguez, Freda F Li, Renjie Huang, Ivanhoe K H Leung, Paul W R Harris, Margaret A Brimble
A novel tyrosine hyperoxidation enables selective peptide cleavage. Chemical science 13 (9) (2022)
Tyla I Alexander, Zoe Tasma, Andrew Siow, Tayla A Rees, Margaret A Brimble, Paul W R Harris, Debbie L Hay, Christopher S Walker
Novel Fluorescently Labeled PACAP and VIP Highlight Differences between Peptide Internalization and Receptor Pharmacology. ACS pharmacology & translational science 6 (1) (2022)
Thomas M Grant, David Rennison, Homayon J Arabshahi, Margaret A Brimble, Patrick Cahill, Johan Svenson
Effect of regio- and stereoisomerism on antifouling 2,5-diketopiperazines. Organic & biomolecular chemistry 20 (47) (2022)
Dianna Truong, Nelson Y S Lam, Meder Kamalov, Mie Riisom, Stephen M F Jamieson, Paul W R Harris, Margaret A Brimble, Nils Metzler Nolte, Christian G Hartinger
A Solid Support-Based Synthetic Strategy for the Site-Selective Functionalization of Peptides with Organometallic Half-Sandwich Moieties. Chemistry (Weinheim an der Bergstrasse, Germany) 28 (12) (2022)
Marzieh Ahangarpour, Iman Kavianinia, Paul A Hume, Paul W R Harris, Margaret A Brimble
N -Vinyl Acrylamides: Versatile Heterobifunctional Electrophiles for Thiol-Thiol Bioconjugations. Journal of the American Chemical Society 144 (30) (2022)
Kuo-Yuan Hung, Renata Kowalczyk, Ami Desai, Margaret A Brimble, John F Marshall, Paul W R Harris
Synthesis and Systematic Study on the Effect of Different PEG Units on Stability of PEGylated, Integrin-αvβ6-Specific A20FMDV2 Analogues in Rat Serum and Human Plasma. Molecules (Basel, Switzerland) 27 (14) (2022)
Zoe Tasma, Andrew Siow, Paul W R Harris, Margaret A Brimble, Simon J O'Carroll, Debbie L Hay, Christopher S Walker
PAC 1 , VPAC 1 , and VPAC 2 Receptor Expression in Rat and Human Trigeminal Ganglia: Characterization of PACAP-Responsive Receptor Antibodies. International journal of molecular sciences 23 (22) (2022)
Paul W R Harris, Andrew Siow, Sung-Hyun Yang, Andrew D Wadsworth, Lyndia Tan, Yann Hermant, Yubing Mao, Chalice An, Cameron C Hanna, Alan J Cameron, Jane R Allison, Aparajita Chakraborty, Scott A Ferguson, Sonya Mros, Kiel Hards, Gregory M Cook, Deborah A Williamson, Glen P Carter, Susanna T S Chan, Gavin A Painter, Veronika Sander, Alan J Davidson, Margaret A Brimble
Synthesis, Antibacterial Activity, and Nephrotoxicity of Polymyxin B Analogues Modified at Leu-7, d-Phe-6, and the N-Terminus Enabled by S-Lipidation. ACS infectious diseases (2022)
Jonathan A Swain, Stephen R Walker, Matthew B Calvert, Margaret A Brimble
The tryptophan connection: cyclic peptide natural products linked via the tryptophan side chain. Natural product reports (2021)
Jonathan S Cebon, Martin Gore, John F Thompson, Ian D Davis, Grant A McArthur, Euan T Walpole, Bernard Mark Smithers, Vincenzo Cerundolo, P Rod Dunbar, Duncan MacGregor, Cyril Fisher, Michael Millward, Paul Nathan, Michael P N Findlay, Peter Hersey, Thomas R Jeffry Evans, Christian Hermann Ottensmeier, Jeremy Marsden, Angus G Dalgleish, Philippa Corrie, Marples Maria, Margaret A Brimble, Geoff Williams, Sintia Winkler, Heather M Jackson, Liliana Endo-Munoz, Candani S A Tutuka, Ralph Venhaus, Lloyd J Old, Dennis Haack, Eugene Maraskovsky, Andreas Behren, Weisan Chen
Results of a randomized, double-blind phase II clinical trial of NY-ESO-1 vaccine with ISCOMATRIX adjuvant versus ISCOMATRIX alone in participants with high-risk resected melanoma. Journal for immunotherapy of cancer 8 (1) (2021)
Michael L Garelja, Rebekah L Bower, Margaret A Brimble, Shanan Chand, Paul W R Harris, Muhammad Aqfan Jamaluddin, Jakeb Petersen, Andrew Siow, Christopher S Walker, Debbie L Hay
Pharmacological characterisation of mouse calcitonin and calcitonin receptor-like receptors reveals differences compared with human receptors. British journal of pharmacology (2021)
Essie M Van Zuylen, Scott A Ferguson, Alan Hughes, David Rennison, Margaret A Brimble, Gregory M Cook
Disruption of Metallostasis in the Anaerobic Human Pathogen Fusobacterium nucleatum by the Zinc Ionophore PBT2. ACS infectious diseases 7 (8) (2021)
Zoe Tasma, Andrew Siow, Paul W R Harris, Margaret A Brimble, Debbie L Hay, Christopher S Walker
Characterisation of agonist signalling profiles and agonist-dependent antagonism at PACAP-responsive receptors: Implications for drug discovery. British journal of pharmacology (2021)
Benjamin L Lu, Geoffrey M Williams, Margaret A Brimble
TLR2 agonists and their structure-activity relationships. Organic & biomolecular chemistry 18 (27) (2021)
Xiao-Bo Ding, Harry R M Aitken, Esperanza S Pearl, Daniel P Furkert, Margaret A Brimble
Synthesis of the C4-C16 Polyketide Fragment of Portimines A and B. The Journal of organic chemistry 86 (18) (2021)
Grace J Drummond, Phillip S Grant, Margaret A Brimble
ent-Atisane diterpenoids: isolation, structure and bioactivity. Natural product reports 38 (2) (2021)
Cameron C Hanna, Yann O Hermant, Paul W R Harris, Margaret A Brimble
Discovery, Synthesis, and Optimization of Peptide-Based Antibiotics. Accounts of chemical research 54 (8) (2021)
Juliana T W Tong, Paul W R Harris, Margaret A Brimble, Iman Kavianinia
An Insight into FDA Approved Antibody-Drug Conjugates for Cancer Therapy. Molecules (Basel, Switzerland) 26 (19) (2021)
Aakanksha Rani, Iman Kavianinia, Paul Hume, Luis M De Leon Rodriguez, Shinji Kihara, David E Williams, Duncan J McGillivray, Natalie O V Plank, Juliet A Gerrard, Justin M Hodgkiss, Margaret A Brimble
Directed self-assembly of peptide-diketopyrrolopyrrole conjugates - a platform for bio-organic thin film preparation. Soft matter 16 (28) (2021)
Phillip S Grant, Margaret A Brimble
seco-Labdanes: A Study of Terpenoid Structural Diversity Resulting from Biosynthetic C-C Bond Cleavage. Chemistry (Weinheim an der Bergstrasse, Germany) 27 (21) (2021)
Emma K Davison, Caitlin E Shepperson, Zoe E Wilson, Margaret A Brimble
Scalable Biomimetic Syntheses of Paeciloketal B, 1-epi-Paeciloketal B, and Bysspectin A. Journal of natural products 84 (8) (2021)
Yann Hermant, Dennise Palpal-Latoc, Nadiia Kovalenko, Alan J Cameron, Margaret A Brimble, Paul W R Harris
The Total Chemical Synthesis and Biological Evaluation of the Cationic Antimicrobial Peptides, Laterocidine and Brevicidine. Journal of natural products 84 (8) (2021)
Scott A Lawrence, Hannah F Robinson, Daniel P Furkert, Margaret A Brimble, Monica L Gerth
Screening a Natural Product-Inspired Library for Anti-Phytophthora Activities. Molecules (Basel, Switzerland) 26 (7) (2021)
Emily S Grant-Mackie, Elyse T Williams, Paul W R Harris, Margaret A Brimble
Aminovinyl Cysteine Containing Peptides: A Unique Motif That Imparts Key Biological Activity. JACS Au 1 (10) (2021)
Kwang-Yoon Ko, Zoe E Wilson, Margaret A Brimble
The Synthesis and Bioactivity of the Marine Macrolide Callyspongiolide. Chemistry (Weinheim an der Bergstrasse, Germany) 27 (8) (2020)
Victor V Yim, Iman Kavianinia, Alan J Cameron, Paul W R Harris, Margaret A Brimble
Direct synthesis of cyclic lipopeptides using intramolecular native chemical ligation and thiol-ene CLipPA chemistry. Organic & biomolecular chemistry 18 (15) (2020)
Emma K Davison, Jared L Freeman, Wanli Zhang, William M Wuest, Daniel P Furkert, Margaret A Brimble
Asymmetric Total Synthesis of the Naturally Occurring Antibiotic Anthracimycin. Organic letters 22 (14) (2020)
Margaret A Brimble
Organic Synthesis: Where to from Now? A Personal Perspective from Down Under. Organic letters 21 (15) (2020)
Phillip S Grant, Daniel P Furkert, Margaret A Brimble
Total Synthesis of (±)-Leonuketal. Organic letters 22 (21) (2020)
Juliana T W Tong, Iman Kavianinia, Scott A Ferguson, Gregory M Cook, Paul W R Harris, Margaret A Brimble
Synthesis of paenipeptin C' analogues employing solution-phase CLipPA chemistry. Organic & biomolecular chemistry (2020)
Hans Choi, Harry J Shirley, Harry R M Aitken, Tim Schulte, Tilo Söhnel, Paul A Hume, Margaret A Brimble, Daniel P Furkert
Intermolecular Diels-Alder Cycloaddition/Cross-Coupling Sequences of 2-Bromo-1,3-butadienes. Organic letters 22 (3) (2020)
Victor V Yim, Iman Kavianinia, Melanie K Knottenbelt, Scott A Ferguson, Gregory M Cook, Simon Swift, Aparajita Chakraborty, Jane R Allison, Alan J Cameron, Paul W R Harris, Margaret A Brimble
"CLipP"ing on lipids to generate antibacterial lipopeptides. Chemical science 11 (22) (2020)
Chloe A Cho, Chao Liang, Janesha Perera, Margaret A Brimble, Simon Swift, Jianyong Jin
Guanidinylated Amphiphilic Polycarbonates with Enhanced Antimicrobial Activity by Extending the Length of the Spacer Arm and Micelle Self-Assembly. Macromolecular bioscience 20 (7) (2020)
Shama S M Dissanayake, Manikandan Ekambaram, Kai Chun Li, Paul W R Harris, Margaret A Brimble
Identification of Key Functional Motifs of Native Amelogenin Protein for Dental Enamel Remineralisation. Molecules (Basel, Switzerland) 25 (18) (2020)
Luis M De Leon Rodriguez, Young-Eun Park, Dorit Naot, David S Musson, Jillian Cornish, Margaret A Brimble
Design, characterization and evaluation of β-hairpin peptide hydrogels as a support for osteoblast cell growth and bovine lactoferrin delivery. RSC advances 10 (31) (2020)
Wanli Zhang, Anna R Kaplan, Emma K Davison, Jared Freeman, Margaret A Brimble, William M Wuest
Building trans-bicyclo[4.4.0]decanes/decenes in complex multifunctional frameworks: the case for antibiotic development. Natural product reports (2020)
Alan J Cameron, Paul W R Harris, Margaret A Brimble
On-Resin Preparation of Allenamidyl Peptides: A Versatile Chemoselective Conjugation and Intramolecular Cyclisation Tool. Angewandte Chemie (International ed. in English) 59 (41) (2020)
Benjamin L Lu, Kerry M Loomes, Debbie L Hay, Paul W R Harris, Margaret A Brimble
Synthesis of isotopically labelled αCGRP8-37 and its lipidated analogue. Journal of labelled compounds & radiopharmaceuticals (2020)
Sung-Hyun Yang, Connor A Clemett, Margaret A Brimble, Simon J O'Carroll, Paul W R Harris
Synthesis and biological evaluation of S-lipidated lipopeptides of a connexin 43 channel inhibitory peptide. RSC medicinal chemistry 11 (9) (2020)
Danielle L Paterson, Jack U Flanagan, Peter R Shepherd, Paul W R Harris, Margaret A Brimble
Variable-Length Ester-Based Staples for α-Helical Peptides by Using A Double Thiol-ene Reaction. Chemistry (Weinheim an der Bergstrasse, Germany) 26 (47) (2020)
Rachel M Gillard, Margaret A Brimble
Benzannulated spiroketal natural products: isolation, biological activity, biosynthesis, and total synthesis. Organic & biomolecular chemistry 17 (36) (2019)
Buzhe Xu, Yann Hermant, Sung-Hyun Yang, Paul W R Harris, Margaret A Brimble
A Versatile Boc Solid Phase Synthesis of Daptomycin and Analogues Using Site Specific, On-Resin Ozonolysis to Install the Kynurenine Residue. Chemistry (Weinheim an der Bergstrasse, Germany) 25 (62) (2019)
Shengping Zhang, Luis M De Leon Rodriguez, Renjie Huang, Ivanhoe K H Leung, Paul W R Harris, Margaret A Brimble
Total synthesis of the proposed structure of talarolide A. Organic & biomolecular chemistry 16 (29) (2019)
Xiao-Bo Ding, Daniel P Furkert, Margaret A Brimble
Highly Diastereoselective Synthesis of Syn-1,3-Dihydroxyketone Motifs from Propargylic Alcohols via Spiroepoxide Intermediates. Angewandte Chemie (International ed. in English) 58 (34) (2019)
Joo Young Jeong, Jonathan Sperry, Margaret A Brimble
Synthesis of the Tetracyclic Cores of the Integrastatins, Epicoccolide A and Epicocconigrone A. The Journal of organic chemistry 84 (18) (2019)
Jin Ng, Harveen Kaur, Thomas Collier, Kevin Chang, Anna E S Brooks, Jane R Allison, Margaret A Brimble, Anthony Hickey, Nigel P Birch
Site-specific glycation of Aβ1-42 affects fibril formation and is neurotoxic. The Journal of biological chemistry 294 (22) (2019)
James M Wood, Daniel P Furkert, Margaret A Brimble
2-Formylpyrrole natural products: origin, structural diversity, bioactivity and synthesis. Natural product reports 36 (2) (2019)
Alan J Cameron, Emma K Davison, Chalice An, Louise A Stubbing, P Rod Dunbar, Paul W R Harris, Margaret A Brimble
Synthesis and SAR Analysis of Lipovelutibols B and D and Their Lipid Analogues. The Journal of organic chemistry 85 (3) (2019)
Johanes K Kasim, Iman Kavianinia, Jin Ng, Paul W R Harris, Nigel P Birch, Margaret A Brimble
Efficient synthesis and characterisation of the amyloid beta peptide, Aβ1-42, using a double linker system. Organic & biomolecular chemistry 17 (1) (2019)

Margaret A Brimble.css-eqlu8i{font-size:small;padding-left:4px;} (M A Brimble, Margaret Brimble)

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Margaret A Brimble (M A Brimble, Margaret Brimble)