Phillip W L Tai (Phillip Wl Tai)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 22

Top Topics

Dna Methylation

Top Venues

EMBO molecular medicine

Nature communications

Human gene therapy

This page only lists publications with an associated author ORCID identifier.

Publications

Qing Xie, Xiupeng Chen, Hong Ma, Yunxiang Zhu, Yijie Ma, Leila Jalinous, Gerald F Cox, Fiona Weaver, Jun Yang, Zachary Kennedy, Alisha Gruntman, Ailing Du, Qin Su, Ran He, Phillip W L Tai, Guangping Gao, Jun Xie
Improved gene therapy for spinal muscular atrophy in mice using codon-optimized hSMN1 transgene and hSMN1 gene-derived promotor. EMBO molecular medicine 16 (4) (2024)
Qing Xie, Xiupeng Chen, Hong Ma, Yunxiang Zhu, Yijie Ma, Leila Jalinous, Gerald F Cox, Fiona Weaver, Jun Yang, Zachary Kennedy, Alisha Gruntman, Ailing Du, Qin Su, Ran He, Phillip W L Tai, Guangping Gao, Jun Xie
Improved gene therapy for spinal muscular atrophy in mice using codon-optimized hSMN1 transgene and hSMN1 gene-derived promotor. EMBO molecular medicine 16 (4) (2024)
Qing Xie, Xiupeng Chen, Hong Ma, Yunxiang Zhu, Yijie Ma, Leila Jalinous, Gerald F Cox, Fiona Weaver, Jun Yang, Zachary Kennedy, Alisha Gruntman, Ailing Du, Qin Su, Ran He, Phillip W L Tai, Guangping Gao, Jun Xie
Improved gene therapy for spinal muscular atrophy in mice using codon-optimized hSMN1 transgene and hSMN1 gene-derived promotor. EMBO molecular medicine 16 (4) (2024)
Qing Xie, Xiupeng Chen, Hong Ma, Yunxiang Zhu, Yijie Ma, Leila Jalinous, Gerald F Cox, Fiona Weaver, Jun Yang, Zachary Kennedy, Alisha Gruntman, Ailing Du, Qin Su, Ran He, Phillip W L Tai, Guangping Gao, Jun Xie
Improved gene therapy for spinal muscular atrophy in mice using codon-optimized hSMN1 transgene and hSMN1 gene-derived promotor. EMBO molecular medicine (2024)
Qing Xie, Xiupeng Chen, Hong Ma, Yunxiang Zhu, Yijie Ma, Leila Jalinous, Gerald F Cox, Fiona Weaver, Jun Yang, Zachary Kennedy, Alisha Gruntman, Ailing Du, Qin Su, Ran He, Phillip W L Tai, Guangping Gao, Jun Xie
Improved gene therapy for spinal muscular atrophy in mice using codon-optimized hSMN1 transgene and hSMN1 gene-derived promotor. EMBO molecular medicine 16 (4) (2024)
Mengtian Cui, Qin Su, Mitchell Yip, Jackson McGowan, Claudio Punzo, Guangping Gao, Phillip W L Tai
The AAV2.7m8 capsid packages a higher degree of heterogeneous vector genomes than AAV2. Gene therapy (2024)
Mitchell Yip, Jing Chen, Yan Zhi, Ngoc Tam Tran, Suk Namkung, Eric Pastor, Guangping Gao, Phillip W L Tai
Querying Recombination Junctions of Replication-Competent Adeno-Associated Viruses in Gene Therapy Vector Preparations with Single Molecule, Real-Time Sequencing. Viruses 15 (6) (2023)
Mitchell Yip, Jing Chen, Yan Zhi, Ngoc Tam Tran, Suk Namkung, Eric Pastor, Guangping Gao, Phillip W L Tai
Querying Recombination Junctions of Replication-Competent Adeno-Associated Viruses in Gene Therapy Vector Preparations with Single Molecule, Real-Time Sequencing. Viruses 15 (6) (2023)
Mitchell Yip, Jing Chen, Yan Zhi, Ngoc Tam Tran, Suk Namkung, Eric Pastor, Guangping Gao, Phillip W L Tai
Querying Recombination Junctions of Replication-Competent Adeno-Associated Viruses in Gene Therapy Vector Preparations with Single Molecule, Real-Time Sequencing. Viruses 15 (6) (2023)
Ngoc Tam Tran, Emilie Lecomte, Sylvie Saleun, Suk Namkung, Cécile Robin, Kristina Weber, Eric Devine, Veronique Blouin, Oumeya Adjali, Eduard Ayuso, Guangping Gao, Magalie Penaud-Budloo, Phillip W L Tai
Human and Insect Cell-Produced Recombinant Adeno-Associated Viruses Show Differences in Genome Heterogeneity. Human gene therapy 33 (7-8) (2022)
Suk Namkung, Ngoc Tam Tran, Sangeetha Manokaran, Ran He, Qin Su, Jun Xie, Guangping Gao, Phillip W L Tai
Direct ITR-to-ITR Nanopore Sequencing of AAV Vector Genomes. Human gene therapy 33 (21-22) (2022)
Terence R Flotte, Oguz Cataltepe, Ajit Puri, Ana Rita Batista, Richard Moser, Diane McKenna-Yasek, Catherine Douthwright, Gwladys Gernoux, Meghan Blackwood, Christian Mueller, Phillip W L Tai, Xuntian Jiang, Scot Bateman, Spiro G Spanakis, Julia Parzych, Allison M Keeler, Aly Abayazeed, Saurabh Rohatgi, Laura Gibson, Robert Finberg, Bruce A Barton, Zeynep Vardar, Mohammed Salman Shazeeb, Matthew J Gounis, Cynthia J Tifft, Florian S Eichler, Robert H Brown, Douglas R Martin, Heather L Gray-Edwards, Miguel Sena-Esteves
AAV gene therapy for Tay-Sachs disease. Nature medicine 28 (2) (2022)
Raed Ibraheim, Phillip W L Tai, Aamir Mir, Nida Javeed, Jiaming Wang, Tomás C Rodríguez, Suk Namkung, Samantha Nelson, Eraj Shafiq Khokhar, Esther Mintzer, Stacy Maitland, Zexiang Chen, Yueying Cao, Emmanouela Tsagkaraki, Scot A Wolfe, Dan Wang, Athma A Pai, Wen Xue, Guangping Gao, Erik J Sontheimer
Self-inactivating, all-in-one AAV vectors for precision Cas9 genome editing via homology-directed repair in vivo. Nature communications 12 (1) (2021)
Ying Kai Chan, Sean K Wang, Colin J Chu, David A Copland, Alexander J Letizia, Helena Costa-Verdera, Jessica J Chiang, Meher Sethi, May K Wang, William J Neidermyer, Yingleong Chan, Elaine T Lim, Amanda R Graveline, Melinda Sanchez, Ryan F Boyd, Thomas S Vihtelic, Rolando Gian Carlo O Inciong, Jared M Slain, Priscilla J Alphonse, Yunlu Xue, Lindsey R Robinson-McCarthy, Jenny M Tam, Maha H Jabbar, Bhubanananda Sahu, Janelle F Adeniran, Manish Muhuri, Phillip W L Tai, Jun Xie, Tyler B Krause, Andyna Vernet, Matthew Pezone, Ru Xiao, Tina Liu, Wei Wang, Henry J Kaplan, Guangping Gao, Andrew D Dick, Federico Mingozzi, Maureen A McCall, Constance L Cepko, George M Church
Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses. Science translational medicine 13 (580) (2021)
Wanru Qin, Guangchao Xu, Phillip W L Tai, Chunmei Wang, Li Luo, Chengjian Li, Xun Hu, Jianxin Xue, You Lu, Qiao Zhou, Qiang Wei, Tianfu Wen, Jiankun Hu, Yuanyuan Xiao, Li Yang, Weimin Li, Terence R Flotte, Yu-Quan Wei, Guangping Gao
Large-scale molecular epidemiological analysis of AAV in a cancer patient population. Oncogene 40 (17) (2021)
Jote T Bulcha, Yi Wang, Hong Ma, Phillip W L Tai, Guangping Gao
Viral vector platforms within the gene therapy landscape. Signal transduction and targeted therapy 6 (1) (2021)
Hung-Lun Hsu, Alexander Brown, Anna B Loveland, Anoushka Lotun, Meiyu Xu, Li Luo, Guangchao Xu, Jia Li, Lingzhi Ren, Qin Su, Dominic J Gessler, Yuquan Wei, Phillip W L Tai, Andrei A Korostelev, Guangping Gao
Structural characterization of a novel human adeno-associated virus capsid with neurotropic properties. Nature communications 11 (1) (2020)
Yeon-Suk Yang, Jun Xie, Dan Wang, Jung-Min Kim, Phillip W L Tai, Ellen Gravallese, Guangping Gao, Jae-Hyuck Shim
Bone-targeting AAV-mediated silencing of Schnurri-3 prevents bone loss in osteoporosis. Nature communications 10 (1) (2019)
Dan Wang, Phillip W L Tai, Guangping Gao
Adeno-associated virus vector as a platform for gene therapy delivery. Nature reviews. Drug discovery 18 (5) (2019)
Yeonsoo Yoon, Dan Wang, Phillip W L Tai, Joy Riley, Guangping Gao, Jaime A Rivera-Pérez
Streamlined ex vivo and in vivo genome editing in mouse embryos using recombinant adeno-associated viruses. Nature communications 9 (1) (2018)
Dan Wang, Jia Li, Chun-Qing Song, Karen Tran, Haiwei Mou, Pei-Hsuan Wu, Phillip W L Tai, Craig A Mendonca, Lingzhi Ren, Blake Y Wang, Qin Su, Dominic J Gessler, Phillip D Zamore, Wen Xue, Guangping Gao
Cas9-mediated allelic exchange repairs compound heterozygous recessive mutations in mice. Nature biotechnology 36 (9) (2018)
Phillip W L Tai, Hai Wu, André J van Wijnen, Gary S Stein, Janet L Stein, Jane B Lian
Genome-wide DNase hypersensitivity, and occupancy of RUNX2 and CTCF reveal a highly dynamic gene regulome during MC3T3 pre-osteoblast differentiation. PloS one 12 (11) (2017)