Wen Xue

ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 19

Top Venues

Nature biotechnology

Nature communications

Genome biology

Nature chemical biology

University of Massachusetts Medical School

Stony Brook University (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Massachusetts Medical School

United States

Assistant Professor :: RNA Therapeutics Institute

Massachusetts Institute of Technology David H Koch Institute for Integrative Cancer Research

United States

Postdoctoral Research :: Dr. Tyler Jacks

Stony Brook University

United States

Graduate Research :: Dr. Scott Lowe

Education History

Stony Brook University

United States

PHD

Nanjing University

China

MSC

Nanjing University

China

BSC

Publications

Bowen Li, Rajith Singh Manan, Shun-Qing Liang, Akiva G R Gordon, Allen Yujie Jiang, Andrew Varley, Guangping Gao, Robert S Langer, Wen Xue, Daniel G Anderson
Combinatorial design of nanoparticles for pulmonary mRNA delivery and genome editing. Nature biotechnology (2023)
Bin Liu, Xiaolong Dong, Chunwei Zheng, David Keener, Zexiang Chen, Haoyang Cheng, Jonathan K Watts, Wen Xue, Erik J Sontheimer
Targeted genome editing with a DNA-dependent DNA polymerase and exogenous DNA-containing templates. Nature biotechnology (2023)
Chunwei Zheng, Bin Liu, Xiaolong Dong, Nicholas Gaston, Erik J Sontheimer, Wen Xue
Template-jumping prime editing enables large insertion and exon rewriting in vivo. Nature communications 14 (1) (2023)
Shun-Qing Liang, Pengpeng Liu, Karthikeyan Ponnienselvan, Sneha Suresh, Zexiang Chen, Christian Kramme, Pranam Chatterjee, Julie Lihua Zhu, Erik J Sontheimer, Wen Xue, Scot A Wolfe
Genome-wide profiling of prime editor off-target sites in vitro and in vivo using PE-tag. Nature methods (2023)
Bin Liu, Xiaolong Dong, Haoyang Cheng, Chunwei Zheng, Zexiang Chen, Tomas C Rodriguez, Shun-Qing Liang, Wen Xue, Erik J Sontheimer
A split prime editor with untethered reverse transcriptase and circular RNA template. Nature biotechnology 40 (9) (2022)
Shun-Qing Liang, Pengpeng Liu, Jordan L Smith, Esther Mintzer, Stacy Maitland, Xiaolong Dong, Qiyuan Yang, Jonathan Lee, Cole M Haynes, Julie Lihua Zhu, Jonathan K Watts, Erik J Sontheimer, Scot A Wolfe, Wen Xue
Genome-wide detection of CRISPR editing in vivo using GUIDE-tag. Nature communications 13 (1) (2022)
Raed Ibraheim, Phillip W L Tai, Aamir Mir, Nida Javeed, Jiaming Wang, Tomás C Rodríguez, Suk Namkung, Samantha Nelson, Eraj Shafiq Khokhar, Esther Mintzer, Stacy Maitland, Zexiang Chen, Yueying Cao, Emmanouela Tsagkaraki, Scot A Wolfe, Dan Wang, Athma A Pai, Wen Xue, Guangping Gao, Erik J Sontheimer
Self-inactivating, all-in-one AAV vectors for precision Cas9 genome editing via homology-directed repair in vivo. Nature communications 12 (1) (2021)
Tingting Jiang, Xiao-Ou Zhang, Zhiping Weng, Wen Xue
Deletion and replacement of long genomic sequences using prime editing. Nature biotechnology (2021)
Pengpeng Liu, Shun-Qing Liang, Chunwei Zheng, Esther Mintzer, Yan G Zhao, Karthikeyan Ponnienselvan, Aamir Mir, Erik J Sontheimer, Guangping Gao, Terence R Flotte, Scot A Wolfe, Wen Xue
Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice. Nature communications 12 (1) (2021)
Tingting Jiang, Jordana M Henderson, Kevin Coote, Yi Cheng, Hillary C Valley, Xiao-Ou Zhang, Qin Wang, Luke H Rhym, Yueying Cao, Gregory A Newby, Hermann Bihler, Martin Mense, Zhiping Weng, Daniel G Anderson, Anton P McCaffrey, David R Liu, Wen Xue
Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope. Nature communications 11 (1) (2020)
Chun-Qing Song, Tingting Jiang, Michelle Richter, Luke H Rhym, Luke W Koblan, Maria Paz Zafra, Emma M Schatoff, Jordan L Doman, Yueying Cao, Lukas E Dow, Julie Lihua Zhu, Daniel G Anderson, David R Liu, Hao Yin, Wen Xue
Adenine base editing in an adult mouse model of tyrosinaemia. Nature biomedical engineering 4 (1) (2019)
Haiwei Mou, Deniz M Ozata, Jordan L Smith, Ankur Sheel, Suet-Yan Kwan, Soren Hough, Alper Kucukural, Zachary Kennedy, Yueying Cao, Wen Xue
CRISPR-SONIC: targeted somatic oncogene knock-in enables rapid in vivo cancer modeling. Genome medicine 11 (1) (2019)
Jooyoung Lee, Haiwei Mou, Raed Ibraheim, Shun-Qing Liang, Pengpeng Liu, Wen Xue, Erik J Sontheimer
Tissue-restricted genome editing in vivo specified by microRNA-repressible anti-CRISPR proteins. RNA (New York, N.Y.) 25 (11) (2019)
Hao Yin, Wen Xue, Daniel G Anderson
CRISPR-Cas: a tool for cancer research and therapeutics. Nature reviews. Clinical oncology 16 (5) (2019)
Jordan L Smith, Haiwei Mou, Wen Xue
Understanding and repurposing CRISPR-mediated alternative splicing. Genome biology 19 (1) (2018)
Dan Wang, Jia Li, Chun-Qing Song, Karen Tran, Haiwei Mou, Pei-Hsuan Wu, Phillip W L Tai, Craig A Mendonca, Lingzhi Ren, Blake Y Wang, Qin Su, Dominic J Gessler, Phillip D Zamore, Wen Xue, Guangping Gao
Cas9-mediated allelic exchange repairs compound heterozygous recessive mutations in mice. Nature biotechnology 36 (9) (2018)
Hao Yin, Chun-Qing Song, Sneha Suresh, Suet-Yan Kwan, Qiongqiong Wu, Stephen Walsh, Junmei Ding, Roman L Bogorad, Lihua Julie Zhu, Scot A Wolfe, Victor Koteliansky, Wen Xue, Robert Langer, Daniel G Anderson
Partial DNA-guided Cas9 enables genome editing with reduced off-target activity. Nature chemical biology 14 (3) (2018)
Haiwei Mou, Jordan L Smith, Lingtao Peng, Hao Yin, Jill Moore, Xiao-Ou Zhang, Chun-Qing Song, Ankur Sheel, Qiongqiong Wu, Deniz M Ozata, Yingxiang Li, Daniel G Anderson, Charles P Emerson, Erik J Sontheimer, Melissa J Moore, Zhiping Weng, Wen Xue
CRISPR/Cas9-mediated genome editing induces exon skipping by alternative splicing or exon deletion. Genome biology 18 (1) (2017)
Hao Yin, Chun-Qing Song, Sneha Suresh, Qiongqiong Wu, Stephen Walsh, Luke Hyunsik Rhym, Esther Mintzer, Mehmet Fatih Bolukbasi, Julie Lihua Zhu, Kevin Kauffman, Haiwei Mou, Alicia Oberholzer, Junmei Ding, Suet-Yan Kwan, Roman L Bogorad, Tatiana A Prikazchikova, Victor Koteliansky, Scot A Wolfe, Wen Xue, Robert Langer, Daniel G Anderson
Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing. Nature biotechnology 35 (12) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Wen Xue